Flavonoides

<p>5-Hydroxy-7,2',3',4',5'-pentamethoxyflavone is a flavone that can be found in coffee. It has been shown to inhibit the enzyme arabinose isomerase and psiadiarabin, which are involved in the conversion of sugar into energy in plants. 5-Hydroxy-7,2',3',4',5'-pentamethoxyflavone also inhibits the plant enzyme phytase, which breaks down phytic acid. Phytic acid is a naturally occurring substance that binds to minerals such as calcium and zinc, preventing their absorption by the body. This compound has not shown any significant activity against bacterial DNA gyrase or topoisomerase IV or human DNA gyrase or topoisomerase II.</p>

<p>Dihydroisoformononetin is an isoflavonoid compound, which is a type of phytoestrogen derived primarily from plant sources, such as legumes and certain medicinal herbs. This compound is of significant interest due to its structural similarity to estrogen, which allows it to interact with estrogen receptors in the body. Its mode of action involves modulating estrogenic activity by acting either as an agonist or antagonist, depending on the tissue context. Such dual behavior makes it an intriguing subject of study in endocrine research.</p>

Dihydrokaempferol-3-O-arabinoside is a flavonoid compound, which is a type of phenolic product found in plants. These compounds are prevalent in various plant species where they contribute to the pigmentation and play a crucial role in plant defense mechanisms. The compound is derived from natural sources, primarily isolated from plant materials rich in flavonoids, such as certain fruits and medicinal herbs.

<p>Tamarixetin-7-O-rutinoside is a flavonoid glycoside, which is a natural compound derived from the Tamarix plant. In nature, it is typically isolated from species within this genus, known for its phytoactive compounds. Tamarixetin-7-O-rutinoside acts primarily through its antioxidant mechanism, which involves scavenging free radicals and reducing oxidative stress within biological systems. This activity is crucial in minimizing cellular damage and maintaining homeostasis.</p>

<p>7-Hydroxyisoflavone-7-O-glucoside is a glucoside derivative of isoflavone, which is a naturally occurring flavonoid often sourced from plants such as legumes and soy. This compound is known for its biochemical properties, primarily its role as an antioxidant and its capacity to modulate inflammation.</p>

<p>7,8-Dihydroxyflavanone is a naturally occurring flavonoid compound, which is typically sourced from various plant species. This compound is structurally characterized by two hydroxyl groups, which are crucial for its biochemical activity. Its mode of action primarily involves the modulation of cellular signaling pathways, including those related to oxidative stress and enzyme inhibition. By interfering with these pathways, 7,8-Dihydroxyflavanone exerts antioxidant and possibly anti-inflammatory effects.</p>

<p>Puerarin is a bioactive isoflavone, which is extracted from the root of Pueraria lobata, commonly known as kudzu. It functions as a phytoestrogen and exhibits multiple pharmacological activities. The mode of action of puerarin involves interacting with various biological pathways, including antioxidant, anti-inflammatory, and neuroprotective mechanisms. It modulates enzyme activities and influences cell signaling pathways, making it a versatile compound for therapeutic research.</p>

Natural glycoside

<p>Aureusidin is a flavonoid pigment, which is a type of plant-derived compound. It is primarily sourced from various flowering plants, where it contributes to the coloration of petals. Aureusidin is synthesized through the enzymatic oxidation of chalcones, which involves flavonoid oxidase activity.</p>

<p>Applications Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.<br>References Shulan S. et al.: Am. J. Chin. Med., 38, 777 (2010); Huang, X. et al.: J. Chrom. B. Anal. Tech. Biomed. Life Sci., 962, 75 (2014);<br></p>

<p>Applications 5α-Pregnane-3-one-20α-ol, is a steroid metabolome, that can be used for in studies of a possible tool for laboratory diagnosis of schizophrenia. It is also a metabolite of Progesterone (P755900) in adipose cells.<br>References Bicikova, M., et al.: J. Steriod Biochem. Mol. Bio., 77, 133 (2013); Zhang, Y., et al.: Mol. Cell. Endocrinology, 298, 76 (2009);<br></p>

<p>Applications 8,9-Di-O-methyl-urolithin D is a derivative of Urolithin D (U847020) which is used in biological studies to evaluate DNA gyrase inhibitory activity of ellagic acid derivatives.<br>References Weidner-Weels, M. A., et al: Bioorg. Med. Chem. Lett., 8, 97 (1998)<br></p>

<p>Applications O-Methylated metabolite of the flavanoid Quercertin (Q509500) with antioxidant activity.<br>References Soobrattee, M.A. et al.: Mut. Res. Fund. Mol. Mech. Mutagen., 579, 200 (2005); Yamamoto, N. et al.: Arch. Biochem. Biophys., 372, 347 (1999);<br></p>

<p>8-Hydroxygenistein-7,8,4'-trimethyl ether is a phytochemical derivative, which is sourced from plant metabolites, specifically isoflavonoids. This compound is modified through methylation processes to enhance its stability and lipophilicity, making it a subject of interest in various biochemical studies. Its mode of action primarily involves interaction with cellular signaling pathways, influencing antioxidant mechanisms and potentially affecting gene expression related to oxidative stress.</p>

<p>8-Prenylpinocembrin is a specialized flavonoid compound, which is a part of the prenylflavonoid class. It is derived from natural sources, primarily plants within the Fabaceae family and propolis from honeybees. The compound is characterized by its prenyl group attached to the flavonoid pinocembrin, enhancing its biological activity through increased lipophilicity and membrane permeability.</p>

<p>Tricetin 7-O-glucoside is a flavonoid glycoside compound, which is a derivative of the naturally occurring flavonoid tricetin. This compound is sourced primarily from certain plant species, including various herbs and foods, where it is present as a minor constituent. The mode of action of Tricetin 7-O-glucoside involves its ability to scavenge free radicals and modulate inflammatory pathways, showcasing both antioxidant and anti-inflammatory properties.</p>

Isomucronulatol 7-O-glucoside is a flavonoid glucoside compound, which is isolated predominantly from various plant species. This compound is known for its comprehensive role as a secondary metabolite that participates in the plant's defense mechanism. The primary mode of action involves its ability to interact with biological targets at the molecular level, potentially exhibiting antioxidant, anti-inflammatory, or other bioactive properties. Isomucronulatol 7-O-glucoside may influence signaling pathways, which can alter physiological responses within organisms.

<p>Licoflavone C is a bioactive flavonoid compound, which is derived from the roots of Glycyrrhiza species. This particular flavonoid is notable for its complex chemical structure that contributes to its biological activity. The primary mode of action of Licoflavone C involves modulation of various cellular pathways, including antioxidant and anti-inflammatory mechanisms. It also influences cell cycle regulation and apoptosis, which are critical in cancer research. The compound's ability to act as a natural antioxidant makes it a valuable candidate in the formulation of skincare products aimed at protecting against oxidative stress. In scientific studies, Licoflavone C has been investigated for its potential anticancer properties, particularly focusing on its effects in inhibiting the proliferation of cancer cells. Furthermore, its role in skin health is under exploration, where its antioxidant capacity and potential to stimulate collagen production may offer benefits in anti-aging products. Such applications make Licoflavone C an intriguing subject for research in natural product chemistry and therapeutic development.</p>

<p>R,S equol 4'-sulfate sodium salt is a synthetic derivative of equol, which is a type of flavonoid metabolite. This compound is primarily sourced from the biotransformation of the isoflavone daidzein through gut microbiota activity. As a sulfate salt, it is more soluble in aqueous environments, which may facilitate its use in various biological contexts.</p>

<p>Isowighteone is a naturally occurring flavonoid, which is derived from various plant sources, particularly in traditional medicinal herbs. Its biological activity stems from its structure, characterized by phenolic hydroxyl groups that enable it to participate in redox reactions, highlighting its antioxidant properties.</p>