Nucleótidos
Los nucleótidos son compuestos orgánicos que sirven como building blocks de los ácidos nucleicos, esenciales para la formación del ADN y ARN. Cada nucleótido está compuesto por una base nitrogenada, una molécula de azúcar y uno o más grupos fosfato. Estos nucleótidos se unen para formar largas cadenas, creando el material genético que lleva y transmite la información genética en todos los organismos vivos. En esta sección, encontrará una amplia variedad de nucleótidos cruciales para la investigación en genética, biología molecular y bioquímica. Son fundamentales para estudiar los procesos genéticos, sintetizar ácidos nucleicos y desarrollar herramientas diagnósticas y terapéuticas. En CymitQuimica, ofrecemos nucleótidos de alta calidad para apoyar su investigación científica y aplicaciones, asegurando precisión y fiabilidad en sus experimentos.
Subcategorías de "Nucleótidos"
Se han encontrado 2636 productos de "Nucleótidos"
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2-Aminoadenosine
CAS:2-Aminoadenosine is a synthetic nucleoside analog of adenosine in which the purine base is 2,6-diaminopurine, featuring an additional amino group at the C2 position. This modification enhances hydrogen bonding potential and alters base-pairing specificity, allowing it to form three hydrogen bonds with uracil or thymine, in contrast to adenine's two. As a result, 2-aminoadenosine has been studied for its impact on nucleic acid stability, replication fidelity, and enzymatic recognition. It has also shown potential in antiviral and anticancer research due to its ability to disrupt normal RNA and DNA metabolism.Fórmula:C10H14N6O4Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:282.26 g/mol5-Chloro-2-iodopyrimidine
CAS:5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It was discovered by a team of chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry. END>Fórmula:C4H2ClIN2Pureza:Min. 95%Forma y color:PowderPeso molecular:240.43 g/mol2,8-Dimethyladenosine
CAS:2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.Fórmula:C12H17N5O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:295.29 g/mol3'-Deoxythymidine
CAS:3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Fórmula:C10H14N2O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:226.23 g/mol2’-Deoxyisoguanosine
CAS:Incorporated in DNA/RNA hybrids and mismatch pairs to analyse helix stabilityFórmula:C10H13N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:267.24 g/mol3'-Deoxycytidine
CAS:3'-Deoxycytidine is a nucleoside analog used to treat hepatitis. It is an inhibitor of the viral enzyme reverse transcriptase and prevents the synthesis of viral DNA by blocking the formation of low-energy hydrogen bonds between the 3'-hydroxyl group and the 5'-phosphate group of deoxyribonucleotide triphosphates. 3'-Deoxycytidine can be synthesized using solid-phase methods, and has been shown to inhibit human immunodeficiency virus (HIV) in control experiments. This drug also has been shown to have anti-inflammatory effects in experimental bladder inflammation models.Fórmula:C9H13N3O4Pureza:Min. 95%Forma y color:White PowderPeso molecular:227.22 g/mol7-Deaza-2',3'-dideoxyguanosine
CAS:7-Deaza-2',3'-dideoxyguanosine is a nucleoside analogue that is silylated on the 2' and 3' hydroxyl groups. It is also substituted with a deoxygenated 7-deaza-2',3'-dideoxyribose moiety. The substitution of the ribose sugar with deoxygenated 7-deaza-2',3'-dideoxyribose prevents the formation of hydrogen bonds between the sugar and phosphate backbones, which inhibits the enzyme ribonucleotide reductase from catalyzing the conversion of ribonucleotides to deoxynucleotides. This in turn blocks DNA synthesis, leading to cell death.br>
7-Deaza-2',3'-dideoxyguanosine has been shown to be effective against Mycobacterium tuberculosis and Mycobacterium avium complex.Fórmula:C11H14N4O3Pureza:Min. 95%Forma y color:PowderPeso molecular:250.26 g/mol2,2'-Anhydrocytidine HCl
CAS:2,2'-Anhydrocytidine HCl is a nucleoside for use as a DNA synthesis inhibitor
Fórmula:C9H11N3O4·HClPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:261.66 g/molN-Phenylpyridin-4-amine
CAS:N-Phenylpyridin-4-amine is a tautomeric compound that has been shown to inhibit the growth of cancer cells. It is able to bind to tyrosine kinase and inhibit its activity, which affects the proliferation of cancer cells. N-Phenylpyridin-4-amine also inhibits mitochondrial functions by inhibiting cytochrome c oxidase. This drug also has an anti-inflammatory effect, inhibiting the production of cytokines such as IL1β, IL6, and TNFα. The biological function of N-Phenylpyridin-4-amine is not yet fully understood. It may be due to the inhibition of protein tyrosine phosphatases (such as PTP1B), which are involved in insulin signalling pathways.Fórmula:C11H10N2Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:170.21 g/mol2,3,5-Tri-O-acetyl α-adenosine
CAS:2,3,5-Tri-O-acetyl α-adenosine is a nucleoside analog of adenosine that has been tri-acetylated. This molecule can be used in research.Fórmula:C16H19N5O7Pureza:Min. 95%Forma y color:PowderPeso molecular:393.35 g/mol2'-O-Propargylcytidine
CAS:2'-O-Propargylcytidine is a novel nucleoside that has been modified from cytidine. It is designed to inhibit the activity of RNA polymerase and to be used in anticancer therapy. The synthesis of 2'-O-propargylcytidine has been achieved by modifying the nucleotide with propargylic chloride, which is then reacted with sodium cyanide. The resulting product is purified by column chromatography and recrystallization.
2'-O-Propargylcytidine is a phosphoramidite that can be used for DNA synthesis or as a monophosphate in RNA synthesis. This high purity product has a CAS number of 206552-85-4 and it can be used as an activator for ribonucleosides, such as adenosine, guanosine, uridine, cytidine, and thymidine.Fórmula:C12H15N3O5Pureza:Min. 95%Forma y color:PowderPeso molecular:281.26 g/mol4-Thiothymidine
CAS:4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.Fórmula:C10H14N2O4SPureza:Min. 98 Area-%Forma y color:Yellow PowderPeso molecular:258.3 g/molN6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine is a nucleoside that is found in DNA. In some cases, the methyl group in this molecule can be modified, which can change its biological activity. N6-Methyl-2'-O-methyladenosine has been shown to reduce the severity of bowel disease and myocardial infarcts in experimental models. The structural analysis of vessels from patients with atherosclerosis revealed that this molecule inhibits vascular calcification. It also decreases expression of MMP-9, a protein involved in nephropathy and diabetic kidney disease. N6-Methyl-2'-O-methyladenosine is able to inhibit the development of vascular injury by blocking the activation of cells and reducing inflammation through pharmacological agents that are used in experimental models for blood vessel injury.Fórmula:C12H17N5O4Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:295.29 g/molCytidine 5'-monophosphate free acid
CAS:Cytidine 5'-monophosphate is a nucleotide that is important in the synthesis of DNA and RNA. It is a precursor to uridine monophosphate (UMP) and uridylic acid (UDP). Cytidine 5'-monophosphate has been found to inhibit the growth of antibiotic-resistant strains of bacteria, such as those resistant to ampicillin, chloramphenicol, tetracycline, kanamycin, and streptomycin. Cytidine 5'-monophosphate also has inhibitory properties against energy metabolism and protein oxidation in bowel disease. This nucleotide has been shown to increase the rate constant for polymerase chain reaction (PCR) by up to 10-fold.Fórmula:C9H14N3O8PPureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:323.2 g/molN2,2'-O-Dimethylguanosine
CAS:N2,2'-O-Dimethylguanosine is a nucleoside that belongs to the category of modified bases. It is synthesized from adenosine and a methyl group by a mutant strain of Escherichia coli. N2,2'-O-Dimethylguanosine can be identified by its characteristic UV-visible spectrum and high retention time on chromatographic columns. It has been shown to inhibit translation in E. coli at concentrations as low as 1 mM and also inhibits growth rate at concentrations as low as 2 mM. The chemical structure of this compound is similar to that of guanosine, but it contains an extra methyl group on its 2' carbon atom. This chemical modification may result in changes in the way the molecule interacts with other molecules or how it functions in the cell. N2,2'-O-Dimethylguanosine was first identified from a mutant strain of Escherichia coli that had been subjected to mutagenesisFórmula:C12H17N5O5Pureza:Min. 95%Peso molecular:311.29 g/mol3-Methylpseudouridine
CAS:3-Methylpseudouridine is a uridine analog that inhibits the enzyme RNA polymerase. It has been shown to inhibit protein synthesis and can be used in the treatment of bacterial infections. 3-Methylpseudouridine is synthesized by solid-phase chemistry on a polymeric support and purified by high-performance liquid chromatography. It has been shown to inhibit the growth of bacteria in cell culture, but its effects on human cells are not known. 3-Methylpseudouridine also binds with high affinity to calf thymus DNA and it can be used as a substrate for aminoglycoside modification studies.Fórmula:C10H14N2O6Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:258.23 g/molN6,N6,2'-O-Trimethyladenosine
CAS:N6,N6,2'-O-Trimethyladenosine is a nucleoside that is found in small quantities in human tissues. It is synthesized by the enzyme polymerase from adenosine and S-adenosyl-L-methionine. N6,N6,2'-O-Trimethyladenosine is structurally similar to guanosine and cytidine and can be modified by nature or synthetic strategies. N6,N6,2'-O-Trimethyladenosine has been shown to have effects on fertility and may be involved in epigenetics as well as tuberculosis. Its role as an epigenetic marker for gene regulation has not been fully determined.Fórmula:C13H19N5O4Pureza:Min. 88 Area-%Forma y color:White PowderPeso molecular:309.32 g/mol1', 2', 3', 4', 5'- ¹³C5-Adenosine
CAS:1', 2', 3', 4', 5'- ¹³C5-Adenosine is adenosine which has all five carbon atoms of the ribose sugar replaced with the stable isotope carbon-13 (^13C). Possible applications are in proteomics studies.Fórmula:C5C5H13N5O4Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:272.2 g/molPseudouridine
CAS:Uridine isomer; found in tRNAFórmula:C9H12N2O6Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:244.2 g/molCytidine
CAS:Cytidine is a nucleoside that belongs to the group of pyrimidine nucleosides. It can be absorbed from the intestine and hydrolyzed to uridine by intestinal enzymes. Cytidine has been shown to inhibit angiogenesis in animal model systems and transfection experiments, as well as being genotoxic in vitro. Cytidine has also been shown to inhibit polymerase chain reactions (PCR) and enzyme activities, such as cytidine deaminase, which converts cytidine into uracil.
Fórmula:C9H13N3O5Pureza:Min. 99 Area-%Forma y color:White Off-White PowderPeso molecular:243.22 g/mol
