Nucleótidos
Subcategorías de "Nucleótidos"
Se han encontrado 2635 productos de "Nucleótidos"
3'-O-Propargyluridine
CAS:3'-O-Propargyluridine is a synthetic nucleoside with an alkyne functional handle on the 3'-position of the sugarFórmula:C12H14N2O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:282.25 g/mol5-(Methylaminomethyl)-2-thiouridine
CAS:5-(Methylaminomethyl)-2-thiouridine is a nucleotide that is important for both DNA and RNA synthesis. It is the methyl donor in the formation of dTMP, an essential component of DNA. 5-(Methylaminomethyl)-2-thiouridine is synthesized by the enzyme thioredoxin reductase using NADPH and glutathione as cofactors. The synthesis of this nucleotide is regulated by hydrogen bonding, which may be due to its ability to form a cationic surfactant with a molecule such as typhimurium. This activity may be due to the presence of a disulfide bond that can react with other molecules such as guanine nucleotides.
5-(Methylaminomethyl)-2-thiouridine has been shown to have structural analysis and chemical biology applications when used in conjunction with E. coli K-12 cells, MethanobrevibFórmula:C11H17N3O5SPureza:(¹H-Nmr) Min. 95 Area-%Forma y color:PowderPeso molecular:303.34 g/mol2-Chloro-2',3'-O-isopropylideneadenosine
CAS:2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.Fórmula:C13H16ClN5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:341.75 g/molN4-Acetyl-2'-deoxy-2'-fluorocytidine
CAS:N4-Acetyl-2'-deoxy-2'-fluorocytidine is a chemical compound that has been the subject of recent research in the field of complex system. It is an aromatic compound that is found in β-pinene, monoterpenes, and other plant products. N4-Acetyl-2'-deoxy-2'-fluorocytidine has not been shown to have any significant biological activity.Fórmula:C11H14FN3O5Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:287.24 g/molCaged GTP
CAS:Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.Fórmula:C18H23N6O16P3Pureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:672.33 g/mol2',3'-Dideoxyadenosine
CAS:2',3'-Dideoxyadenosine is a nucleoside analog that inhibits HIV replication and is a competitive inhibitor of adenylyl cyclase. This latter action reduces levels of cyclic adenosine monophosphate (cAMP)
Fórmula:C10H13N5O2Pureza:Min. 95%Forma y color:PowderPeso molecular:235.25 g/mol5'-Deoxy-5'-iodoguanosine
CAS:5'-Deoxy-5'-iodoguanosine is a synthetic nucleoside that is used as a molecular probe to study the biochemical and physiological effects of UV irradiation. It has been shown to be reactive under in vitro conditions, and to have functionalities in vivo. 5'-Deoxy-5'-iodoguanosine has been used as a polymerase inhibitor, and it can also be used for the synthesis of oligonucleotides.Fórmula:C10H12IN5O4Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:393.14 g/mol2'-Deoxy-5'-O-DMT-N6-methyladenosine
CAS:2'-Deoxy-5'-O-DMT-N6-methyladenosine is a mutant of the natural nucleoside adenosine which has been synthesized as a model for the study of the enzyme ribonucleotide reductase. The mutant has a frameshift mutation, and the resulting protein is unable to catalyze DNA synthesis. It can be complemented by adding wild type nucleotides to regenerate the original sequence. 2'-Deoxy-5'-O-DMT-N6-methyladenosine inhibits the synthetase activity of ribonucleotide reductase and also inhibits polymerization of erythromycin B and styrene. 2'-Deoxy-5'-O-DMT-N6-methyladenosine has been shown to inhibit dehydrogenase activity in auxotrophs of Escherichia coli.Fórmula:C32H33N5O5Pureza:Min. 98 Area-%Forma y color:Off-White PowderPeso molecular:567.64 g/mol5-Chloro-5'-deoxyuridine
5-Chloro-5'-deoxyuridine is a nucleoside that is used as an antiviral agent and anticancer drug. It inhibits the viral DNA polymerase by acting as a phosphoramidite in the synthesis of viral DNA. 5-Chloro-5'-deoxyuridine is also used in the treatment of leukemia cells, which are resistant to other anticancer drugs. The high purity and modified nucleosides make this product highly desirable for research purposes. The novel syntheses of this product make it a desirable choice for many researchers.Fórmula:C9H11ClN2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:262.65 g/mol2'-Deoxy-N2-DMF-guanosine
CAS:2'-Deoxy-N2-DMF-guanosine is a synthetic nucleoside that is used as a primer in DNA sequencing and hybridization experiments. It binds to the 5' end of single-stranded DNA and is complementary to guanosine. The 2'-deoxy group on the sugar moiety prevents the formation of hydrogen bonds with other bases, which increases stability. In addition, it has a high affinity for dna binding proteins. This synthetic nucleoside has been shown to be useful in clinical diagnostics and can be used as a probe for detecting diazirine residues in DNA sequences.Fórmula:C13H18N6O4Pureza:Min. 97 Area-%Forma y color:White Off-White PowderPeso molecular:322.33 g/mol2'-Deoxyuridine
CAS:2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.
Fórmula:C9H12N2O5Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:228.21 g/mol3'-Amino-2',3'-dideoxyguanosine
CAS:3'-Amino-2',3'-dideoxyguanosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.Fórmula:C10H14N6O3Pureza:(%) Min. 95%Forma y color:Off-White PowderPeso molecular:266.26 g/mol2-Thiouridine
CAS:2-Thiouridine is a uridine derivative that acts as a precursor for protein synthesis. It is synthesized from 2-amino-5-thiazole carboxylic acid and uracil in two steps, first with the formation of 2-thiouridine monophosphate and then with the conversion to 2-thiouridine diphosphate. The synthesis of 2-thiouridine is catalyzed by the enzyme uridine phosphorylase, which converts it to uridine monophosphate. 2-Thiouridine has been shown to have immunomodulatory effects in cell culture systems and animal models. These effects are believed to be due to its ability to act as an inhibitor of fatty acid synthase, which generates fatty acids from acetyl CoA. This process prevents the production of prostaglandins and leukotrienes, thereby reducing inflammation.Fórmula:C9H12N2O5SPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:260.27 g/molXanthosine 5'-monophosphate disodium salt
CAS:Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Fórmula:C10H11N4Na2O9PPureza:Min. 95%Forma y color:White Slightly Yellow PowderPeso molecular:408.17 g/mol2'-Deoxy-N3-methyluridine
CAS:2'-Deoxy-N3-methyluridine is a nucleoside analog that is used as a substrate in the synthesis of DNA. It can be incorporated into the DNA strand by enzymes called thymidylate synthases. 2'-Deoxy-N3-methyluridine has been shown to inhibit bacterial growth in cell cultures, and it is also active against marine sponges. The protonation state of the molecule determines its hydrophobicity and can be altered by adding a test compound to the solution. Hydrophobic molecules are more likely to bind with water molecules than hydrophilic molecules, which are more soluble in water.Fórmula:C10H14N2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:242.23 g/mol2',3'-Dideoxyuridine
CAS:Research tool for anti-viral and anti-cancer studies
Fórmula:C9H12N2O4Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:212.21 g/molN4,N4-Dimethylcytidine
CAS:N4,N4-Dimethylcytidine is a nucleoside that is an analog of cytidine. It has antiviral potency against influenza virus and inhibits the RNA-dependent DNA polymerase. N4,N4-Dimethylcytidine can be used to treat influenza and other viruses that are resistant to other antiviral drugs. This drug can be used in cell culture to inhibit the production of mismatched DNA strands, which is important for the replication of RNA viruses such as influenza. N4,N4-Dimethylcytidine also has been shown to be an inhibitor of miRNA activity in mammalian cells.
Fórmula:C11H17N3O5Pureza:(%) Min. 95%Forma y color:White PowderPeso molecular:271.27 g/molN4-Benzoyl-2'-O-methylcytidine
CAS:N4-Benzoyl-2'-O-methylcytidine is a triester of cytidine that is used in various biochemical research applications. It is enzymatically synthesized from cytidine and benzoyl chloride. N4-Benzoyl-2'-O-methylcytidine has been shown to have the same electrophoretic mobility as 5-hydroxyl cytidine, but it does not react with hydroxylamine to produce the corresponding hydroxylated product. This compound has also been used to study nucleic acid structure and function.
Fórmula:C17H19N3O6Pureza:Min. 95%Forma y color:PowderPeso molecular:361.35 g/mol6-Methylpurine-2'-deoxyriboside
CAS:6-Methylpurine-2'-deoxyriboside (6MPdR) is a nucleoside analog that inhibits viral polymerase activity. It is used in the treatment of bowel diseases, such as inflammatory bowel disease and hepatitis C. 6MPdR can be used to treat cancer by inhibiting cellular proliferation and inducing apoptosis. This drug has been shown to inhibit leishmania growth in cell culture. 6MPdR can be administered orally or intravenously, and is pegylated for greater stability in the blood stream.
Fórmula:C11H14N4O3Pureza:Min. 95%Forma y color:PowderPeso molecular:250.25 g/molCoenzyme A hydrate
CAS:Coenzyme A hydrate is essential in the metabolism of fatty acids and the synthesis of acetyl-CoA. It is also employed in pharmaceutical applications, especially in drug development and formulation. Its distinctive properties improve drug solubility and bioavailability, making it an essential component in the creation of therapeutic agents.Fórmula:C21H36N7O16P3S·xH2OPureza:(Enzymatic) Min. 75%Forma y color:White Off-White Slightly Yellow PowderPeso molecular:767.54 g/mol
