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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3569 productos de "Nucleósidos"

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  • N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester

    CAS:

    N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester, also known as Acelarin, is primarily used in cancer treatment, including leukemia and solid tumors.

    Fórmula:C25H27F2N4O8P
    Pureza:Min. 98 Area-%
    Forma y color:Powder
    Peso molecular:580.47 g/mol

    Ref: 3D-ND158438

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  • 3',5'-Bis-O-(t-butyldimethylsilyl)thymidine

    CAS:

    3',5'-Bis-O-(t-butyldimethylsilyl)thymidine is a novel nucleoside phosphoramidite that can be used in the synthesis of oligonucleotides. This compound has antiviral and anticancer activities and is an excellent building block for the synthesis of modified nucleosides. 3',5'-Bis-O-(t-butyldimethylsilyl)thymidine is a high quality, high purity chemical with a CAS number of 40733-26-4.

    Fórmula:C22H42N2O5Si2
    Pureza:Min. 95%
    Peso molecular:470.7 g/mol

    Ref: 3D-QBA73326

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  • 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine

    CAS:

    3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.

    Fórmula:C23H17Cl2FN2O7
    Pureza:Min. 95%
    Peso molecular:523.29 g/mol

    Ref: 3D-ND22464

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  • N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine

    CAS:

    N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.

    Fórmula:C24H23N5O5
    Pureza:Min. 95%
    Peso molecular:461.5 g/mol

    Ref: 3D-SFA97940

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  • 6-Amino-1-methyluracil

    CAS:

    6-Amino-1-methyluracil is a synthetic drug that is used in the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. It is also used to treat cancer, such as leukemia and in the treatment of bacterial infections. 6-Amino-1-methyluracil inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase. This inhibition prevents DNA replication and transcription, which leads to cell death. 6-Amino-1-methyluracil binds to cellular proteins through its amino group and hydroxyl group, which are not involved in its chemical reactions. 6-Amino-1-methyluracil has shown great promise as a template molecule for the synthesis of new drugs.

    Pureza:Min. 95%

    Ref: 3D-NA03107

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  • 3-Benzoylpyridine

    CAS:

    3-Benzoylpyridine is a natural product that has been isolated from the plant Plectranthus fruticosus. It is an aromatic compound, with a trifluoromethyl group and a hydroxy group. 3-Benzoylpyridine has been shown to react with amines in the presence of hydrogen gas to form 1H-1,2,3-triazole derivatives. This reaction is catalyzed by light or UV irradiation. The absorption maxima for 3-benzoylpyridine are at 270 nm and 330 nm in water and ethanol, respectively. In addition, 3-benzoylpyridine is able to combine with hydroxide ions to form the corresponding salt, which can be reduced to yield the nitrogen containing heterocyclic ring (3-benzo[b]pyridin).

    Fórmula:C12H9NO
    Pureza:Min. 95%
    Peso molecular:183.21 g/mol

    Ref: 3D-NB70237

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  • 2',3'-Dideoxy-2',2'-difluorocytidine

    CAS:

    2',3'-Dideoxy-2',2'-difluorocytidine is a monophosphate derivative of the antiviral and anticancer drug 2',3'-dideoxycytidine. It is an activator of DNA synthesis, nucleosides, and nucleotides. It is also a phosphoramidite for the synthesis of oligonucleotides and modified ribonucleosides. 2',3'-Dideoxy-2',2'-difluorocytidine has CAS number 124708-94-7. It is available in high purity and quality, which makes this product suitable for research purposes.

    Pureza:Min. 95%

    Ref: 3D-ND158370

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  • 3',5'-Di-O-acetyl-2'-deoxyguanosine

    CAS:

    3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.

    Fórmula:C14H17N5O6
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:351.32 g/mol

    Ref: 3D-ND04500

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  • 8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.
    Fórmula:C10H17N6O13P3·xNa
    Pureza:Min. 95%
    Peso molecular:522.2 g/mol

    Ref: 3D-NA12011

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  • Cytidine 5'-monophosphate sodium salt

    CAS:

    Cytidine 5'-monophosphate sodium salt is a nucleotide that is found in RNA and DNA. Cytidine 5'-monophosphate sodium salt is an intermediate in the biosynthesis of uridine, choline, and saccharose. It also plays an important role in the immune system as it can be a precursor for immunoglobulins. The reaction rate of cytidine 5'-monophosphate sodium salt with lipase has been shown to be constant at pH 7.5-8.0 and 37°C. This product has been shown to have emulsifying properties by forming micelles with water-immiscible solvents such as hexane or heptane, which may be due to its ability to form hydrogen bonds with other molecules such as saccharose or guanosine. Cytidine 5'-monophosphate sodium salt can also be used as a chromatographic material for separating saccharose from other sugars

    Fórmula:C9H14N3O8P·xNa
    Pureza:Min. 95 Area-%
    Forma y color:White Off-White Powder
    Peso molecular:323.2 g/mol

    Ref: 3D-NC00007

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  • 5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole

    CAS:
    5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as an
    Fórmula:C18H18Cl2N2O7
    Pureza:Min. 95%
    Peso molecular:445.25 g/mol

    Ref: 3D-ND16534

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  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG


    N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG is a nucleotide analog with antiviral and anticancer activity. It is considered to be a novel nucleoside analogue. It is synthesized by attaching an acetyl group to the 2' position of the adenosine moiety, which prevents phosphorylation by kinase enzymes. This inhibits DNA synthesis and induces apoptosis in cancer cells.

    Pureza:Min. 95%
    Forma y color:Powder

    Ref: 3D-ND57353

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  • 5'-O-DMT-N2-phenylacetylguanosine

    CAS:

    5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.

    Fórmula:C39H37N5O8
    Pureza:Min. 95%
    Peso molecular:703.76 g/mol

    Ref: 3D-ND08925

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  • 2’-Deoxy-2-methyladenosine

    CAS:

    2’-Deoxy-2-methyladenosine is a nucleoside that is chemically synthesized by the phosphorylation of 2,6-diaminopurine. It has been shown to be an effective activator of RNA polymerase and it also has anticancer properties. 2’-Deoxy-2-methyladenosine can be used as a substitute for thymidine in DNA synthesis. This nucleoside has also been shown to inhibit bacterial growth in culture by inhibiting DNA synthesis and protein synthesis. It is a modified nucleoside that can be used for the synthesis of DNA, RNA, or ribonucleic acids. The CAS number for this compound is 110952-90-4.

    Pureza:Min. 95%

    Ref: 3D-ND163169

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  • Uridylyl-3'-5'-cytidine ammonium salt


    Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.

    Fórmula:C18H27N6O13P
    Pureza:Min. 95%
    Peso molecular:566.41 g/mol

    Ref: 3D-NU46048

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  • N6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution

    CAS:

    Modulator of P2Y receptors

    Fórmula:C11H18N5O13P3
    Pureza:Min. 95%
    Peso molecular:521.21 g/mol

    Ref: 3D-NM71656

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  • 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt


    Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Fórmula:C13H22N3O14P3•(C6H15N)x
    Pureza:Min. 99 Area-%
    Forma y color:Powder
    Peso molecular:537.25 g/mol

    Ref: 3D-NA180287

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  • 3'-epi-5-chloro-2'-deoxyuridine

    CAS:

    3'-epi-5-chloro-2'-deoxyuridine is a nucleotide analog that has been shown to inhibit the growth of cells in tissue culture. It is not active against bacteria, but can be used as an antineoplastic agent for the treatment of cancer. 3'-epi-5-chloro-2'-deoxyuridine is metabolized by a number of enzymes, including mononucleotide reductase, thymidylate synthase, and cytosine deaminase. The reaction mechanism for this drug has been studied using nuclear dna polymerases and proteases. The metabolism of 3'-epi-5-chloro-2'-deoxyuridine results in its incorporation into DNA by means of an enzymatic reaction with DNA polymerase. The incorporation of the analog into DNA leads to cell death due to lysis or inhibition of protein synthesis.

    Fórmula:C9H11ClN2O5
    Pureza:Min. 95%
    Peso molecular:262.65 g/mol

    Ref: 3D-NE16712

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  • 5-Aminoallyl-2'-deoxyuridine

    CAS:

    5-Aminoallyl-2'-deoxyuridine is a bifunctional alkylating agent that has low affinity for DNA. It is used in the laboratory to measure the rate of synthesis of thymidylate, which is one of the four deoxythymidylate needed for DNA synthesis. 5-Aminoallyl-2'-deoxyuridine has been shown to be a stable complex with sulfoxide, which can be used as an alkylation agent in the laboratory. 5-Aminoallyl-2'-deoxyuridine has also been shown to have high affinity for cellular nucleic acids in l1210 cells and have a high uptake. The sequence of 5-aminoallyl-2'-deoxyuridine is: 5-(N-(2-(5-aminoallylamino)ethyl)-N-(carboxyethyl)glycine)-2',3',5'-triiod

    Fórmula:C12H18N4O4
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:282.3 g/mol

    Ref: 3D-NA02924

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  • 3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt

    Producto controlado

    3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt is a novel antiviral nucleoside phosphoramidite that has been shown to be an effective activator in the synthesis of diphosphate and triphosphate analogs. The novel antiviral nucleoside phosphoramidite was synthesized from 3'-azido-3'-deoxythymidine, methyl bromoacetate and sodium hydroxide in methanol at room temperature. It is structurally similar to the natural nucleosides, deoxyribonucleosides and ribonucleosides with modifications on the sugar moiety and phosphate group. This compound is a high quality synthetic material for use in pharmaceutical research, as an anticancer agent and as a potential antiviral drug.
    Fórmula:C16H17D3N5NaO10
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:468.36 g/mol

    Ref: 3D-NA04586

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  • 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid

    CAS:
    5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is a pyrimidine derivative that inhibits protein kinases. The compound has been shown to inhibit the activity of protein kinase C, which is involved in mediating inflammatory responses, and phosphorylation of the insulin receptor substrate 1. 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is an efficient inhibitor of kinases and can be used as a lead compound for the development of new compounds with therapeutic potential.
    Fórmula:C6H5BrN2O2S
    Pureza:Min. 95%
    Peso molecular:249.09 g/mol

    Ref: 3D-NB44268

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  • 2'-TFA-NH-dG

    CAS:

    2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.

    Fórmula:C12H13F3N6O5
    Pureza:Min. 95%
    Peso molecular:378.26 g/mol

    Ref: 3D-NT57541

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  • 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole

    CAS:
    1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole is a nucleoside that can be used as an activator for phosphoramidite synthesis. It is also known to have antiviral, anticancer, and antimalarial properties. 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole has been shown to inhibit the proliferation of human leukemia cells in culture. It has also been shown to suppress HIV replication in vitro by inhibiting viral RNA synthesis.
    Fórmula:C14H17NO3
    Pureza:Min. 95%
    Peso molecular:247.3 g/mol

    Ref: 3D-ND06396

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  • 2',3',5'-Tri-O-benzoyl-2-thiouridine

    CAS:

    2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).

    Fórmula:C30H24N2O8S
    Pureza:Min. 95%
    Peso molecular:572.59 g/mol

    Ref: 3D-NT16569

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  • Ammonium 4-nitrobenzoate dihydrate

    CAS:

    Ammonium 4-nitrobenzoate dihydrate is a corrosion inhibitor that prevents the corrosion of metal parts and other materials. It is used in the production of plastics, coatings, adhesives, and lubricants. The corrosion inhibition activity of aminobenzoates can be attributed to their ability to form hydrogen phosphate (HPO) anions as well as their ability to complex with metal ions. The hydration process is also important for the corrosion inhibition activity of ammonium 4-nitrobenzoate dihydrate. This process involves the release of water molecules from the ammonium salt, which provide a protective coating around the metal surface. Ammonium 4-nitrobenzoate dihydrate also has additive properties that are beneficial for other industrial applications such as antistatic agents, surfactants, and stabilizers.

    Pureza:Min. 95%

    Ref: 3D-NA30959

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  • 8-Aza-2'-deoxyadenosine


    8-Aza-2'-deoxyadenosine is an anion that is cytotoxic to cells and can be activated to form a phosphate ester. It has been shown to have a higher cytotoxicity than adenosine in cell cultures, but is less effective in animal studies. 8-Aza-2'-deoxyadenosine has been shown to have a significant toxicity in rats and mice when administered at doses greater than 500 mg/kg body weight. The activation of 8-aza-2'-deoxyadenosine into the phosphate ester can be stereoselective. This activation has also been shown to cause enhancement of tumor growth inhibition.

    Pureza:Min. 95%

    Ref: 3D-NA141794

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  • 3'-O-Methyl-5'-guanylic acid

    CAS:

    3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.

    Fórmula:C11H16N5O8P
    Pureza:Min. 95%
    Peso molecular:377.25 g/mol

    Ref: 3D-NM165059

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  • 8-(p-Chlorophenylthio)-cGMP

    CAS:

    8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.

    Fórmula:C16H15ClN5O7PS
    Pureza:Min. 95%
    Peso molecular:487.81 g/mol

    Ref: 3D-NC182802

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  • 5'-O-DMT-3'-O-hexylphthalimidouridine


    5'-O-DMT-3'-O-hexylphthalimidouridine is an antiviral and anticancer agent that is a nucleoside analog. It inhibits viral replication by preventing the production of RNA, which is necessary for the synthesis of DNA. It also prevents the proliferation of cancer cells and induces apoptosis by inhibiting DNA synthesis. 5'-O-DMT-3'-O-hexylphthalimidouridine is a monophosphate that has been modified to form a phosphoramidite. The synthesized product was purified to high purity and quality with a novel structure.

    Fórmula:C44H45N3O10
    Pureza:Min. 95%
    Peso molecular:775.86 g/mol

    Ref: 3D-ND08518

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  • 2-(2-Cyclohexylethoxy)adenosine

    CAS:

    2-(2-Cyclohexylethoxy)adenosine (CX-5461) is a new chemical entity that has been shown to have an incremental effect on muscle contraction. The mechanism of action of CX-5461 is not fully understood, but it has been shown to be nonselective and to bind to adenosine receptors. This binding produces a response in the cell similar to that of adenosine, which is a small molecule involved in the regulation of blood pressure and heart rate. CX-5461 also binds with platelet membranes at the site of inflammation and causes vasodilation. It has been shown to be effective in animal models of pertussis, where it reduces the severity of muscle spasms and increases the duration before death. These effects are due to CX-5461's ability to lower intracellular calcium concentrations by preventing calcium release from internal stores or from outside sources such as muscle cells or platelets.

    Fórmula:C18H27N5O5
    Pureza:Min. 95%
    Peso molecular:393.44 g/mol

    Ref: 3D-NC16523

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  • 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:

    2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation into

    Fórmula:C10H12N5O11P3·4Li
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:498.91 g/mol

    Ref: 3D-ND32077

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  • 5'-O-tert-Butyldimethylsilylthymidine

    CAS:
    5'-O-tert-Butyldimethylsilylthymidine is a nucleoside that is used for the synthesis of oligoribonucleotides. It can be prepared by treating 5'-O-tert-butyldimethylsilylthymidine with alkyl bromides in the presence of microwaves and catalytic amounts of a base such as sodium methoxide. The product is purified by vacuum distillation or column chromatography and can be hydrolyzed to uridine, which has been shown to have anti-inflammatory properties. 5'-O-tert-Butyldimethylsilylthymidine can also be converted into deoxyribose through the use of ultrasound.
    Fórmula:C16H28N2O5Si
    Pureza:Min. 95%
    Peso molecular:356.5 g/mol

    Ref: 3D-NB08945

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  • 2'-Deoxy-5'-O-DMT-adenosine

    CAS:

    2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.

    Fórmula:C31H31N5O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:553.61 g/mol

    Ref: 3D-ND57357

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  • 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

    CAS:
    5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.
    Fórmula:C41H49N4O9P
    Pureza:Min. 95%
    Peso molecular:772.82 g/mol

    Ref: 3D-ND163164

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  • Nonadecanoyl coenzyme A

    CAS:

    Nonadecanoyl coenzyme A is a fatty acid that is produced by the bovine liver and has been shown to have anabolic effects. Nonadecanoyl CoA is involved in the synthesis of various lipids, such as phospholipids, cholesterol, and glycolipids. It also plays a role in biosynthesis of fatty acids and in regulating ATP production. Nonadecanoyl CoA is synthesized from acetate by the enzyme acetyl-CoA carboxylase (ACC). ACC catalyzes the conversion of acetyl-CoA to malonyl-CoA, which can then be used for fatty acid synthesis. Nonadecanoyl CoA has been found to play an important role in regulating mitochondrial function through its ability to activate long-chain acyl-CoAs desaturase (LCAD). LCAD converts long-chain acyl-CoAs into their corresponding dicarboxylic acids.

    Fórmula:C40H72N7O17P3S
    Pureza:Min. 95%
    Peso molecular:1,048.02 g/mol

    Ref: 3D-NN47201

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  • 2'-Deoxycytidine-5'-carboxylic acid

    CAS:

    2'-Deoxycytidine-5'-carboxylic acid (2'-DC) is a modified nucleoside that has been used as an anticancer, antiviral, and synthetic agent. 2'-DC inhibits the synthesis of DNA by binding to the enzyme DNA polymerase. It also inhibits viral replication by inhibiting the activity of reverse transcriptase and can be used as a potential anti-HIV drug. In addition, 2'-DC has been shown to have cytotoxic effects against cancer cells in vitro. This compound is synthesized from cytidine 5-monophosphate and phosphoramidite reagents in high purity and quantity. The CAS number for this compound is 4603-72-9.

    Fórmula:C9H11N3O5
    Pureza:Min. 95%
    Peso molecular:241.2 g/mol

    Ref: 3D-ND158446

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  • 5’-O-DMT cET-N2-isopropylguanosine 3’-OCE amidite

    CAS:

    Please enquire for more information about 5'-ODMT cEt G Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Fórmula:C46H56N7O9P
    Peso molecular:881.95 g/mol

    Ref: 3D-PO184478

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  • rac-Lamivudine acid

    CAS:

    Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.

    Fórmula:C8H9N3O4S
    Pureza:Min. 95%
    Peso molecular:243.24 g/mol

    Ref: 3D-NL27534

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  • 5'-O-DMT-2'-O-propylphthalimidouridine


    5'-O-DMT-2'-O-propylphthalimidouridine is a synthetic nucleoside that has antiviral and anticancer properties. It is used as a precursor for the synthesis of other nucleosides, including uridine and cytidine. 5'-O-DMT-2'-O-propylphthalimidouridine can be modified with phosphoramidites to create novel modified nucleosides. The chemical name is 1-(5'-O-dimethoxytrityl)-2-[(2' -propyl)thio]uracil. This drug has CAS number 61381-14-4 and molecular weight of 271.11 g/mol.

    Fórmula:C41H39N3O10
    Pureza:Min. 95%
    Peso molecular:733.78 g/mol

    Ref: 3D-ND08421

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  • 3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine


    3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.

    Fórmula:C32H31FN2O8
    Pureza:Min. 95%
    Peso molecular:590.6 g/mol

    Ref: 3D-NA08460

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  • 2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å


    2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.

    Pureza:Min. 95%

    Ref: 3D-ND11609

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  • Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate

    CAS:

    Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.

    Fórmula:C8H8F3N3O2
    Pureza:Min. 95%
    Peso molecular:235.16 g/mol

    Ref: 3D-NE57446

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  • 2-Methylthio-6-chloropurine

    CAS:

    2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.

    Fórmula:C6H5CIN4S
    Pureza:Min. 95%
    Peso molecular:304.11 g/mol

    Ref: 3D-NM29024

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  • 5-Fluorouridine

    CAS:

    5-Fluorouridine is an anticancer drug that belongs to the group of modified nucleosides. It is a synthetic nucleoside analogue that inhibits viral and DNA synthesis and can be used as antiviral agents. 5-Fluorouridine has also been shown to inhibit RNA synthesis in vitro. This compound is converted to uracil by deoxyribonucleotide reductase, which results in the formation of 5-fluoro-2'-deoxyuridine monophosphate (5FdUMP) and 5-fluoro-2'-deoxyuridine diphosphate (5FdUDP). The latter has been shown to inhibit DNA synthesis in vitro.

    Fórmula:C9H11FN2O6
    Pureza:Min. 95%
    Peso molecular:262.19 g/mol

    Ref: 3D-CDA18080

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  • 2'-Deoxy-5'-O-DMT-5-iodocytidine


    2'-Deoxy-5'-O-DMT-5-iodocytidine is a modified nucleoside that has antiviral and anticancer properties. 2'-deoxy-5'-O-DMT-5-iodocytidine is able to activate the DNA polymerase, ribonucleotide reductase, and deoxyribonucleotide reductase enzymes. This product can be used as a monophosphate or diphosphate. The CAS number for this compound is 141475-07-4.

    Pureza:Min. 95%

    Ref: 3D-ND158763

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  • 3'-deoxy-3',4'-didehydrouridine

    CAS:

    3'-deoxy-3',4'-didehydrouridine is a synthetic nucleoside that inhibits viral replication. It is an antiviral agent that has been shown to be effective against DNA and RNA viruses. The synthesis of this compound has been described in the literature. This product is available in high purity and high quality, and CAS No. 2166167-51-5. 3'-deoxy-3',4'-didehydrouridine has also been shown to have anticancer activity, and is a novel synthetic nucleoside.

    Fórmula:C9H10N2O5
    Pureza:Min. 95%
    Peso molecular:226.19 g/mol

    Ref: 3D-ND32094

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  • 2',5'-Dideoxyinosine

    CAS:

    2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.

    Fórmula:C10H12N4O3
    Pureza:Min. 95%
    Peso molecular:236.23 g/mol

    Ref: 3D-ND08407

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  • 5'-O-Tosylthymidine

    CAS:

    5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.

    Fórmula:C17H20N2O7S
    Pureza:Min. 95%
    Peso molecular:396.42 g/mol

    Ref: 3D-NT10016

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  • 2',3'-O-Isopropylideneinosine

    CAS:

    2',3'-O-Isopropylideneinosineis a nucleoside for use in research applications

    Fórmula:C13H16N4O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:308.3 g/mol

    Ref: 3D-NI03500

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  • Guanylyl-3',5'-guanosine ammonium salt

    CAS:

    Guanylyl-3',5'-guanosine ammonium salt is a novel antiviral agent that has high antiviral activity against influenza A virus. It is a guanine derivative which has been modified to include an aminopropyl group and an ammonium cation. This compound also acts as an activator for deoxyribonucleosides, nucleotides, and ribonucleosides. Guanylyl-3',5'-guanosine ammonium salt may be used in the manufacture of DNA, RNA, and phosphoramidites. This compound also has anticancer effects by inhibiting the proliferation of tumor cells and inducing apoptosis.

    Fórmula:C20H25N10O12P·H3N
    Pureza:Min. 95%
    Peso molecular:645.48 g/mol

    Ref: 3D-NG11482

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  • N2-Benzoylguanosine

    CAS:

    N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.

    Fórmula:C17H17N5O6
    Pureza:Min. 95%
    Forma y color:White to beige solid.
    Peso molecular:387.35 g/mol

    Ref: 3D-NB06331

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  • N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite

    CAS:

    A 5'-3’ “reverse” (or “inverse”) amidites

    Fórmula:C47H52N7O7P
    Pureza:Min. 95%
    Peso molecular:857.93 g/mol

    Ref: 3D-PB08532

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  • 2',3',5'-Tri-O-acetylinosine

    CAS:

    2′,3′,5′-Tri-O-acetylinosine is a protected form of the nucleoside inosine, with potential for use in the preparation of modified nucleotides and nucleoside analogs.

    Fórmula:C16H18N4O8
    Pureza:Min. 95%
    Forma y color:White To Off-White Solid
    Peso molecular:394.34 g/mol

    Ref: 3D-NT06708

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  • 5′-O-DMT-LNA N-Bz adenosine

    CAS:

    5′-O-DMT-LNA N-Bz adenosine is a novel nucleoside that has been modified with an aminooxy group. The compound is synthesized by the phosphoramidite method and it is designed for use in antiviral and anticancer research. 5′-O-DMT-LNA N-Bz adenosine can be used as a substrate for DNA polymerases and other enzymes to produce nucleic acid strands. This product is CAS No. 206055-74-5, monophosphate, Phosphoramidites, Synthetic, Deoxyribonucleosides, Anticancer, Ribonuclesides, High purity.

    Fórmula:C39H35N5O7
    Pureza:Min. 95%
    Peso molecular:685.73 g/mol

    Ref: 3D-ND182842

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  • Spacer-c3 cep

    CAS:

    Spacer-C3 Cep is a novel modified nucleoside phosphoramidite. It has been chemically modified with a spacer arm and 3-Cep (1,2-diaminoethane). Spacer-C3 Cep is an activator for DNA polymerases, which are enzymes that synthesize DNA from deoxyribonucleosides. The modified nucleoside phosphoramidite has antiviral and anticancer activities. It can be used in the synthesis of oligodeoxyribonucleotides for gene therapy or as a monophosphate for the preparation of DNA probes. Spacer-C3 Cep can also be used to synthesize ribonucleotide analogs that inhibit viral replication by inhibiting RNA synthesis.

    Fórmula:C33H43N2O5P
    Pureza:Min. 95%
    Peso molecular:578.7 g/mol

    Ref: 3D-KEA89423

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  • 3′-Guanylic acid disodium

    CAS:

    3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.

    Fórmula:C10H14N5O8P•Na2
    Pureza:Min. 95%
    Peso molecular:409.2 g/mol

    Ref: 3D-NG182606

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  • 2'-Deoxy-a-adenosine

    CAS:

    2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.

    Fórmula:C10H13N5O3
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:251.25 g/mol

    Ref: 3D-ND08541

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  • 5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine

    CAS:

    5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine is a nucleoside that is used as an antiviral and anticancer agent. It is a novel compound that has not been previously described in the literature. 5’-O-DMT-2’-O,4’-C methylene 5 methyluridine has been shown to inhibit the replication of the herpes virus in vitro (in cell culture) and in vivo (in animals). This compound also inhibits the proliferation of cancer cells by inhibiting DNA synthesis. It may be used as an anticancer agent or an antiviral agent.

    Pureza:Min. 95%

    Ref: 3D-ND163159

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  • 5-Methyl-L-uridine

    CAS:

    5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.

    Fórmula:C10H14N2O6
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:258.23 g/mol

    Ref: 3D-NM06240

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  • Ribavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution

    CAS:

    Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.

    Fórmula:C8H15N4O14P3•(C6H15N)x
    Pureza:Min. 95 Area-%
    Forma y color:Clear Liquid
    Peso molecular:789.73

    Ref: 3D-NR12804

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  • Adenosine 5'-monophosphate sodium

    CAS:

    Adenosine 5'-monophosphate sodium is a nucleotide that is involved in the energy metabolism of cells. It has been shown to inhibit oxidative injury and to activate signal pathways in response to external stimuli, such as glucose deprivation. Adenosine 5'-monophosphate sodium can be synthesized from ATP by the enzyme adenosine kinase.

    Fórmula:C10H13N5O7P·Na
    Pureza:Min. 98 Area-%
    Forma y color:White Powder
    Peso molecular:369.2 g/mol

    Ref: 3D-NA10369

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  • 2'-Deoxy-4'-ethynyl-2-fluoroadenosine

    CAS:

    2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long

    Fórmula:C12H12FN5O3
    Pureza:Min. 95%
    Peso molecular:293.25 g/mol

    Ref: 3D-ND45638

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  • DMTr-TNA-C(Bz)-amidite

    CAS:

    Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Fórmula:C45H50N5O8P
    Peso molecular:819.9 g/mol

    Ref: 3D-PD184482

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  • 2'-O-Methyluridine-5'-monophosphate triethylammonium

    CAS:

    2'-O-Methyluridine-5'-monophosphate triethylammonium salt is a modified nucleoside analogue that is an antiviral agent. It inhibits viral replication by acting as an inhibitor of RNA synthesis and DNA polymerase, which are necessary for the virus to replicate. This compound also has anticancer activity and can be used as a chemotherapeutic agent. 2'-O-Methyluridine-5'-monophosphate triethylammonium salt is synthesized from uracil, phosphoramidite, and triethylamine. It has high purity and high quality with a CAS number of 67624-43-5.

    Fórmula:C10H15N2O9P•(C6H15N)2
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:439.21 g/mol

    Ref: 3D-NM167710

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  • 2-Chloroadenosine 5'-monophosphate triethylamine salt

    CAS:

    2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.

    Fórmula:C10H13ClN5O7P·C12H30N2
    Pureza:Min. 95%
    Peso molecular:584.05 g/mol

    Ref: 3D-NC10383

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  • 2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate

    CAS:

    10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position

    Pureza:Min. 95%

    Ref: 3D-NM71847

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  • 2',3'-Dideoxy-3',5-difluorocytidine

    CAS:

    2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.

    Pureza:Min. 95%

    Ref: 3D-ND144806

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    100mg
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  • dNaM

    CAS:

    dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.

    Fórmula:C16H18O4
    Pureza:Min. 95%
    Peso molecular:274.31 g/mol

    Ref: 3D-SUB89319

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  • Archaeosine

    CAS:

    Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.

    Fórmula:C12H16N6O5
    Pureza:Min. 95%
    Peso molecular:324.29 g/mol

    Ref: 3D-NA159487

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