Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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N6-Succinyl adenosine
CAS:N6-Succinyl adenosine is a biochemical that is involved in the transfer of fatty acids across membranes. It has been shown to be effective in transfection experiments, where it can be used to increase the expression of genes. N6-Succinyl adenosine has also been shown to be an important substrate for various dehydrogenases. Deficiency of these enzymes leads to orotic aciduria, which is characterized by elevated levels of orotic acid in blood and urine and may lead to mental retardation. A linear calibration curve was generated for diagnosis purposes, with the enzyme activities being determined using a logistic regression model.Fórmula:C14H17N5O8Pureza:Min. 95%Forma y color:White PowderPeso molecular:383.31 g/mol5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine
CAS:5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is a nucleoside that can be used as an activator for ribonucleosides. It has been shown to have anticancer, antiviral and antiviral activities. 5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is synthesized by the reaction of 2'-deoxycytidine with tertbutyldimethylchlorosilane in the presence of triethylamine. The product may be purified by crystallization or chromatography.Fórmula:C15H26IN3O4SiPureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:467.38 g/mol1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine
CAS:1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine is a cytosine analog that is structurally similar to the antiviral drug tenofovir. It has been shown to be active against human serum and logarithmic growth phase cells, as well as cancer cell lines. 1-(2,3-Dideoxy-2-fluoropentofuranosyl)cytosine inhibits HIV infection in vitro by binding to the viral reverse transcriptase enzyme, blocking its activity and preventing DNA synthesis. This drug also inhibits the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in cell culture.Fórmula:C9H12FN3O3Pureza:Min. 95%Peso molecular:229.21 g/mol4-Thiothymidine
CAS:4-Thiothymidine is a nucleoside analog that is converted to thymidine by the enzyme thymidine kinase. It has been shown to inhibit the growth of human skin cancer cells by binding to DNA duplexes and inhibiting the synthesis of new DNA strands. 4-Thiothymidine has also been shown to be effective against radiation-induced damage in cultured human cells and inhibits tumor growth in mice bearing a transplantable mouse skin cancer. 4-Thiothymidine can be used as an inhibitor for chemotherapy or radiation therapy for cancer patients. It is active on both site-specific and cell-specific gene targets, with a reactive hydrogen bond that helps stabilize its formation.Fórmula:C10H14N2O4SPureza:Min. 98 Area-%Forma y color:Yellow PowderPeso molecular:258.3 g/mol3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine
CAS:3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine (3DFT) is a nucleoside analogue of thymidine. It has been shown to be an efficient inhibitor of HIV replication in vitro and in vivo. 3DFT is able to inhibit virus production by blocking the viral reverse transcriptase enzyme, which is responsible for copying the viral genomic RNA into DNA. This drug also inhibits the activity of human immunodeficiency virus type 1 integrase, which is an enzyme that catalyses the integration of proviral DNA into host cell chromosomes. 3DFT is a potent inhibitor of HIV infection in vitro and in vivo and has also been shown to inhibit other viruses such as cytomegalovirus, herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, coxsackie B4 virus, echovirus 7, and erythrovirus 9.Fórmula:C10H11FN2O4Pureza:Min. 95%Peso molecular:242.2 g/mol5-Methoxy-2-thiouridine
CAS:5-Methoxy-2-thiouridine is the peracylated form of thiouracil. It is a reactive oxygen species, which can cause primary site lesions in cells. 5-Methoxy-2-thiouridine is a posttranscriptional modification that leads to conformational changes in the anticodon loop of tRNA molecules. This modification prevents the anticodon from pairing with its corresponding codon during translation, thereby inhibiting protein synthesis. The modifications also affect RNA processing and stability and lead to changes in gene expression.Pureza:Min. 95%2’-C-Methylisocytidine
CAS:2’-C-Methylisocytidine is a novel antiviral drug that is a deoxyribonucleoside. It is synthesized by the reaction of cytidine with 2’-chloroethylisocyanate to form a methylated derivative, which is converted to 2’-C-methylisocytidine via phosphorylation. This nucleoside has been shown to have anticancer properties and may be used as an activator for the synthesis of DNA or RNA.
Pureza:Min. 95%Flavin adenine dinucleotide
CAS:Flavin adenine dinucleotide, also known as FAD, plays a crucial role in several enzymatic reactions involved in metabolism. It is essential for the function of flavoproteins, which are involved in processes such as the electron transport chain and the citric acid cycle.Fórmula:C27H33N9O15P2Pureza:Min. 95%Forma y color:PowderPeso molecular:785.5 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.Fórmula:C9H11FN6O4Pureza:Min. 95%Forma y color:Off-White PowderPeso molecular:286.22 g/molN2-Benzyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:N2-Benzyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-guanosine 3'-CE phosphoramidite is a nucleoside which is the phosphate ester of guanosine. It is synthesized from N4-benzoylcytidine 5'-O-DMT phosphoramidite and 2'O,N-bis(tertiarybutyl)dimethylsilylguanosine 3'-Ce phosphoramidite. The product is used in the synthesis of deoxyribonucleosides and as an activator for ribonucleosides. It has anticancer, antiviral, and antimalarial activities.
Pureza:Min. 95%Adenosine 5'-monophosphate disodium salt
CAS:Adenosine 5'-monophosphate disodium salt (AMP-Na2) is a chemical compound that has been used in the study of metabolic disorders. It belongs to the class of ethylene diamines and has been shown to increase the glomerular filtration rate. Ammonium adenosine 5'-monophosphate disodium salt has also been shown to increase the activity of glutamate decarboxylase, which converts glutamate into GABA, an inhibitory neurotransmitter. The neutral pH optimum for AMP-Na2 is 6.5-7.5, which may be due to its lysine residues. AMP-Na2 has a carbonyl group that can be oxidized by reactive oxygen species and cause oxidative injury to cells in vivo and in vitro. This damage was found mainly in microglia cells, which are responsible for removing dead or damaged neurons from the central nervous system (CNS). AMP-Na2 also activates adFórmula:C10H12N5Na2O7PPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:391.19 g/mol2'-Deoxy-6-thioguanosine - Bio-X ™
CAS:This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C10H13N5O3SPureza:Min. 95%Forma y color:PowderPeso molecular:283.31 g/mol3’-Azido-3’-deoxy-5-fluoro-b-L-uridine
CAS:3’-Azido-3’-deoxy-5-fluoro-b-L-uridine is a novel, activator ribonucleoside that is an analog of the natural nucleoside uridine. It has high quality and purity. This compound is used to synthesize deoxyribonucleosides, diphosphate, phosphoramidites, modified, anticancer and antiviral agents.Pureza:Min. 95%5-Methyl-2-thiouridine
CAS:5-Methyl-2-thiouridine is a nucleotide that is found in the type strain of Escherichia coli. It has been shown to be an effective inhibitor of protein synthesis, with optimum concentration at 0.1 mM. 5-Methyl-2-thiouridine binds to the ribosome and inhibits its activity. 5-Methyl-2-thiouridine also interacts with human mitochondrial RNA and alters its structure, leading to an antibody response that protects against infection by the bacteria in question. This nucleotide has also been shown to inhibit bacterial growth in wastewater treatment plants. The chemical structures of 5-methyluridine are similar to those of uridine except for a methyl group on the second carbon atom (5 position). The presence of this methyl group confers increased water permeability and decreased kinetic energy on the molecule, which can be detected using nuclear magnetic resonance spectroscopy.
Fórmula:C10H14N2O5SPureza:Min. 95%Forma y color:White PowderPeso molecular:274.29 g/mol9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine
CAS:9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is a modified nucleoside with anticancer activity. It has been shown to be an effective activator of DNA, RNA, and protein synthesis in vitro. This drug has also been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and influenza A virus. 9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is an analog of the natural purine metabolite hypoxanthine that can be synthesized in high purity.Pureza:Min. 95%3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone
CAS:3,5-Bis-O-(4-methylbenzoyl)-2-C-methyl-D-ribonic acid gama-lactone is a novel synthetic nucleoside. It is an activation agent that releases 2'-deoxyuridine 5'-triphosphate from ribonucleotides. This nucleoside has been shown to have antiviral and anticancer properties, as well as the ability to inhibit HIV replication in vitro. It is also used for the preparation of oligonucleotide analogs for use in molecular biology research and molecular medicine.Pureza:Min. 95%5'-O-DMT-N2-DMF-guanosine
CAS:5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.Fórmula:C34H36N6O7Pureza:(%) Min. 85%Peso molecular:640.69 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-CE phosphoramidite
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a chemical compound used in the synthesis of oligonucleotides. It is a building block for the construction of nucleic acid chains, specifically designed for postsynthetic modification strategies. The compound contains a thymine base, a 2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl sugar moiety, and a 3'-CE phosphoramidite group.Fórmula:C40H48FN4O8PPureza:Min. 95%Forma y color:White To Off-White SolidPeso molecular:762.82 g/mol5'-O-(4,4'-Dimethoxytrityl)adenosine
CAS:5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.
Fórmula:C31H31N5O6Pureza:Min. 95 Area-%Forma y color:White Off-White PowderPeso molecular:569.61 g/mol2'-Deoxy-5-iodouridine - EP
CAS:2'-Deoxy-5-iodouridine is a nucleoside analog that inhibits the replication of viruses and other DNA-containing organisms. 2'-Deoxy-5-iodouridine also has inhibitory properties on cell nuclei, which may be due to its ability to bind with DNA and prevent the synthesis of RNA or protein. 2'-Deoxy-5-iodouridine has been shown to inhibit the growth of human HL60 cells in vitro at an optimum concentration of 20 μM. It also inhibits the replication of murine sarcoma virus at an optimum concentration of 16 μM. 2'-Deoxy-5-iodouridine has significant cytotoxicity against solid tumours in mice, which may be due to its ability to inhibit hydrogen fluoride (HF) induced lipid peroxidation and reduce glutathione levels.Fórmula:C9H11IN2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:354.1 g/mol
