Nucleósidos
Se han encontrado 3570 productos de "Nucleósidos"
2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate
CAS:2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a nucleoside that is used as an antiviral agent in the treatment of herpes zoster and varicella zoster. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis. 2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a novel nucleotide analogue that has been modified to improve its stability, solubility and bioavailability. It can be used as a starting material for the synthesis of phosphoramidites by reacting with phosphorous pentoxide at elevated temperatures and pH. CAS No. 151151-32-5Fórmula:C9H12N3O10P2·Na3Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:453.12 g/mol5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite
CAS:5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite is a labile, thermally sensitive chemical compound. It is used as a building block for the synthesis of oligonucleotides.
Fórmula:C45H56N7O9PPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:869.96 g/mol5-Bromo-5'-O-tert-butyldimethylsilyl-2',3'-O-isopropylideneuridine
CAS:5-Bromo-5'-O-tert-butyldimethylsilyl-2',3'-O-isopropylideneuridine is a novel nucleoside analog that has been synthesized to inhibit the synthesis of RNA. The 5-Bromo-5'-O-tert-butyldimethylsilyl-2',3'-O-isopropylideneuridine is an Activator, which inhibits the activity of ribonucleotide reductase. It also exhibits antiviral and anticancer activities.Fórmula:C18H29BrN2O6SiPureza:Min. 95%Forma y color:PowderPeso molecular:477.42 g/mol5’-ODMT cET-uridine 3’-OCE amidite
CAS:5’-ODMT cET-uridine 3’-OCE amidite is a bicyclic nucleoside that is commonly known as BNA for bicyclic nucleic acid or LNA for locked nucleic acid. It comprises a bridge between the 4' and 2' carbon atoms to lock the ribose ring into a fixed configuration. The BNA or LNA incorporated oligonucleotides are useful to regulate gene expression via antisense mechanisms.Fórmula:C41H49N4O9PPeso molecular:772.82 g/mol2',3'-Di-O-benzoyluridine
CAS:2',3'-Di-O-benzoyluridine is a nucleoside for use in research applications
Fórmula:C23H20N2O8Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:452.41 g/mol5’-ODMT-cET-5-methyluridine 3’-OCE amidite
CAS:5’-ODMT-cET-5-methyluridine 3’-OCE amidite is a bicyclic nucleoside that is commonly known as BNA for bicyclic nucleic acid or LNA for locked nucleic acid. It comprises a bridge between the 4' and 2' carbon atoms to lock the ribose ring into a fixed configuration. The BNA or LNA incorporated oligonucleotides are useful to regulate gene expression via antisense mechanisms.Fórmula:C42H51N4O9PPeso molecular:786.86 g/moldNTP pre-mixes, 10 mM aqueous solution
CAS:dATP, dTTP, dCTP and dGTP pre-mixed in a single vialFórmula:C10H16N5O12P3Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:491.18 g/mol2'-Deoxyxanthosine
CAS:Producto controlado2'-Deoxyxanthosine is a chemical compound with biochemical properties that can be used as a pharmaceutical drug. It is a nucleoside analogue that interferes with DNA synthesis. 2'-Deoxyxanthosine inhibits the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides, and prevents the formation of DNA in cells. This drug is also known to have anti-tumor effects, including angiogenesis inhibition and cytostatic activity. The reaction mechanism of 2'-deoxyxanthosine involves nitrous acid, which reacts with the 2' hydroxyl group of xanthosine to form the nitroso intermediate and then reacts with oxygen to produce nitrite and hydrogen peroxide. The final step in this process is the cleavage of xanthosine by nitrite into xanthine and oxalate. This drug has been shown to be reactive at neutral pH conditionsFórmula:C10H12N4O5Pureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:268.23 g/molAdenosine 5'-diphosphate disodium salt
CAS:Adenosine 5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. It is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
Fórmula:C10H13N5Na2O10P2Pureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:471.16 g/mol4-Bromo-3,5-dichloropyridine
CAS:4-Bromo-3,5-dichloropyridine is a reactive intermediate that is used as a reagent in organic synthesis. It has low basicity and reacts with lithium to form the lithium salt. The salt can be deprotonated to form the bromide anion, which is more reactive than the chloride anion. 4-Bromo-3,5-dichloropyridine can also be used for the selective isomerization of ketones and related compounds. Bromine is added to prevent side reactions with oxygen. The intermediates are generated at the site of reaction by using an excess of diisopropylamide over bromination agent.
Fórmula:C5H2BrCl2NPureza:Min. 95%Peso molecular:226.89 g/mol2'-O-(2-Methoxyethyl)cytidine
CAS:2'-O-(2-Methoxyethyl)cytidine is a nutrient that is used to maintain the dry weight of Lactobacillus acidophilus cultures. It is also used as a texturizing agent in food products. 2'-O-(2-Methoxyethyl)cytidine has been shown to increase the rate of lactose hydrolysis and reduce the viscosity of yogurt by activating L. acidophilus. 2'-O-(2-Methoxyethyl)cytidine is also used as a dietary supplement for people with intestinal disorders, such as irritable bowel syndrome. It can be found in sodium salts and n-methyl-d-glucamine.Fórmula:C12H19N3O6Pureza:Min. 95%Forma y color:PowderPeso molecular:301.3 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite is a novel, high quality, high purity, and deoxyribonucleoside. It is a phosphoramidite that is used in the synthesis of oligodeoxyribonucleotides and has antiviral, anticancer, and anti-inflammatory activities. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudouridine 3'-CE phosphoramidite inhibits the replication of DNA by inhibiting the synthesis of RNA from DNA. This deoxynucleoside also activates nucleases to degrade proteins that are involved in cancer cell proliferation.Fórmula:C45H61N4O9PSiPureza:Min. 95%Forma y color:PowderPeso molecular:861.05 g/molCytidine 5'-triphosphate disodium dihydrate
CAS:Cytidine 5'-triphosphate (CTP) disodium dihydrate prevents the action of aspartate carbamoyltransferase, an enzyme involved in pyrimidine biosynthesis. CTP serves as a molecule of high energy and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.Fórmula:C9H16N3O14P3•(H2O)2•Na2Pureza:Min. 95%Forma y color:PowderPeso molecular:565.17 g/mol5'-O-DMT-N2-isobutyrylguanosine
CAS:5'-O-DMT-N2-isobutyrylguanosine is a novel phosphoramidite monophosphate, which has been modified with an isobutyryl group. This compound was synthesized in order to be used as a nucleoside analogue and antimetabolite for the treatment of cancer. It also has antiviral properties and inhibits the replication of DNA by inhibiting transcription. 5'-O-DMT-N2-isobutyrylguanosine is an anticancer agent that can be used to treat tumors that are resistant to other chemotherapy drugs. It also inhibits the growth of cells by preventing the synthesis of proteins needed for cell division.
Fórmula:C35H37N5O8Pureza:Min. 95%Forma y color:White PowderPeso molecular:655.7 g/mol2'-O-Methyluridine
CAS:2'-O-Methyluridine is a chemical compound that is used in the synthesis of RNA. It is an analog of uridine and has been shown to have antiviral and anticancer properties. 2'-O-Methyluridine inhibits protein synthesis by competing with uridine for the active site of the enzyme ribonucleotide reductase, which converts ribonucleotides to dNMPs. This compound also inhibits RNA synthesis by disrupting the pairing of adenine and cytosine residues in RNA strands. 2'-O-Methyluridine has been shown to inhibit growth in some types of cancer cells, including colorectal adenocarcinoma cells. It may also be useful as a chemotherapeutic agent against HIV, as it inhibits virus replication by inhibiting reverse transcription and DNA synthesis.
Fórmula:C10H14N2O6Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:258.23 g/mol2'-Deoxy-4-thiouridine
CAS:2'-Deoxy-4-thiouridine is a pyrimidine nucleoside for a range of applications
Fórmula:C9H12N2O4SPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:244.27 g/molGuanosine 3',5'-bisdiphosphate lithium salt - 100mM aqueous solution
CAS:Regulates gene transcription; inhibits the synthesis of tRNA and rRNAFórmula:C10H17N5O17P4·xLiPureza:Min. 85 Area-%Forma y color:Colorless PowderPeso molecular:602.16 g/molN3-Methylthymidine
CAS:N3-Methylthymidine is a metalloprotease inhibitor that has been shown to inhibit the activity of epidermal growth factor (EGF). N3-Methylthymidine is also an effective inhibitor of HIV infection. The inhibitory effect on HIV infection is due to the competitive inhibition of viral protease and subsequent degradation of viral proteins. N3-Methylthymidine inhibits the synthesis and release of infectious herpes simplex virus particles. This drug also inhibits the growth of human tumor cells in culture by inhibiting cell proliferation, most likely due to its ability to inhibit EGF. An analytical method for determining the concentration of this drug in plasma using chemical ligation has been developed.Fórmula:C11H16N2O5Pureza:Min. 95%Forma y color:White PowderPeso molecular:256.26 g/mol5-Aza-7-deazaguanosine
CAS:5-Aza-7-deazaguanosine is a nucleoside analogue that has antiviral activity against herpes simplex virus, influenza, and other DNA viruses. 5-Aza-7-deazaguanosine is an analog of guanosine with the addition of a 7-deaza group on the nitrogen atom. This drug inhibits viral replication by inhibiting the polymerase function of the viral NS5B protein, which is essential for DNA synthesis. The structure activity relationship studies have shown that this compound has anti-hepatitis B virus activity, but not against hepatitis C virus. 5-Aza-7-deazaguanosine has been shown to be effective in animal models as well as in humans without any significant toxicity issues.Fórmula:C10H13N5O5Pureza:Min. 95%Forma y color:PowderPeso molecular:283.24 g/mol2'-Deoxyadenosine 5'-O-thiophosphate sodium salt
CAS:2'-Deoxyadenosine 5'-O-thiophosphate sodium salt is a synthetic nucleotide that has antiviral, anticancer and antitumor properties. It is a modified deoxyribonucleoside and it activates the synthesis of DNA by acting as an activator. This drug is not found in nature and it has shown to inhibit the growth of human breast cancer cells in cell culture.Fórmula:C10H14N5O5PSPureza:Min. 95%Peso molecular:347.29 g/mol
