Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
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2',3',5'-Tri-O-benzoyl-2-thiouridine
CAS:<p>2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).</p>Fórmula:C30H24N2O8SPureza:Min. 95%Peso molecular:572.59 g/mol2',3'-Didehydro-2',3'-dideoxyuridine
CAS:<p>2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.</p>Fórmula:C9H10N2O4Pureza:Min. 95%Peso molecular:210.19 g/mol6-Aminothymine
CAS:<p>6-Aminothymine is a polyamine that exerts its inhibitory activity by hydrogen bonding to the enzyme's active site. It has been shown to inhibit protein synthesis and growth factor synthesis in HL-60 cells. 6-Aminothymine also has cancer inhibiting properties, which may be due to its ability to bind DNA and interfere with replication or transcription.</p>Fórmula:C5H7N3O2Pureza:Min. 95%Peso molecular:141.13 g/molGuanosine-5'-carboxylic acid
CAS:Guanosine-5'-carboxylic acid (GCA) is a nucleotide that interacts with mammalian cells. It reacts in a vessel to form the antigen, which can then be detected using an antibody. The conformational properties of this molecule are important for its function, and it has been shown to be effective against cancer cells in vivo. GCA has also been shown to interact with toll-like receptor 2 and induce an antibody response.Fórmula:C10H11N5O6Pureza:Min. 95%Peso molecular:297.22 g/molN2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS:N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.Fórmula:C43H53N8O6PPureza:Min. 95%Forma y color:Off white solid.Peso molecular:808.93 g/mol3'-Deoxy-3'-fluorocytidine
CAS:<p>3'-Deoxy-3'-fluorocytidine is an activating agent that has been shown to inhibit coxsackie virus and other single-stranded RNA viruses. It is a nucleoside analogue that binds to the enzyme ribofuranoside, preventing the formation of the active site. 3'-Deoxy-3'-fluorocytidine has also been shown to inhibit the biochemical reactions involving S-adenosylhomocysteine hydrolase, which catalyzes the conversion of S-adenosylhomocysteine into adenosine, a precursor for DNA synthesis. Mechanistic studies have indicated that 3'-deoxy-3'-fluorocytidine inhibits enzymatic activity through stereochemical interactions with S-adenosylhomocysteine hydrolase.</p>Fórmula:C9H12FN3O4Pureza:Min. 95%Peso molecular:245.21 g/mol2’-Deoxy-N2-dimethylguanosine
CAS:<p>2’-Deoxy-N2-dimethylguanosine is a novel antiviral agent that inhibits the replication of human DNA viruses by binding to their diphosphate or monophosphate regions and inhibiting ribonucleotide reductase. It has also been shown to have anticancer properties in vitro.</p>Pureza:Min. 95%6-(Trifluoromethyl)uracil
CAS:6-(Trifluoromethyl)uracil is a synthetic analog of uracil, which is a nucleobase that is found in RNA. It can be synthesized by reacting phosphorus oxychloride and trifluoromethyl chloride to form the corresponding chloroformate ester, followed by hydrolysis with anhydrous potassium carbonate. The compound has been shown to inhibit bacterial growth in bioassays and also has the ability to react with amines. 6-Trifluoromethyluracil has a constant chlorine atom that forms hydrogen bonds with other molecules, such as ammonia or amines, which may have antibacterial properties.Fórmula:C5H3F3N2O2Pureza:Min. 95%Peso molecular:180.08 g/mol2-Iodo-2’-deoxyadenosine
CAS:2-Iodo-2’-deoxyadenosine is a novel nucleoside that is a modified adenosine. It has been shown to possess anticancer activity. 2-Iodo-2’-deoxyadenosine has a high degree of cytotoxicity and can induce apoptosis in cancer cells. This drug also inhibits the growth of herpes simplex virus type 1 (HSV) and HIV, which are both types of viruses that infect humans. The antiviral activity may be due to the inhibition of viral DNA synthesis or RNA transcription. 2-Iodo-2’-deoxyadenosine is synthesized from adenine, iodine, and sulfuric acid with high purity and quality. It is not active against bacteria because it does not inhibit bacterial DNA gyrase or topoisomerase IV enzymes.Pureza:Min. 95%8-(p-Chlorophenylthio)-cGMP
CAS:<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Fórmula:C16H15ClN5O7PSPureza:Min. 95%Peso molecular:487.81 g/mol5'-O-tert-Butyldimethylsilyluridine
CAS:5'-O-tert-Butyldimethylsilyluridine (5'-O-TBDMSU) is a nucleoside that is used in the synthesis of nucleic acid probes. It is selective for the uridine residues in RNA and DNA, which are found at the 5' position. Sodium hydride reacts with this compound to form the corresponding hydroxyl group. This allows for further nucleobase additions or halogen substitutions to be made to the molecule, as well as desilylation reactions. 5'-O-TBDMSU can also be used to synthesize heteroaromatic nucleic acids and nucleotide derivatives.Fórmula:C15H26N2O6SiPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:358.46 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine
CAS:<p>4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine is a novel nucleoside analog that can be activated to the monophosphate form for incorporation into DNA. It has antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine has been shown to inhibit the proliferation of cultured tumor cells, suggesting a potential use in cancer chemotherapy.</p>Fórmula:C9H10FN5O5Pureza:Min. 95%Peso molecular:287.2 g/mol2'-Deoxy-N4,5-dimethylcytidine
CAS:<p>2'-Deoxy-N4,5-dimethylcytidine is an activator that has the ability to activate a variety of nucleoside analogs. The compound is synthetically derived and used as an antiviral agent. It can be modified at the 5' position with phosphate groups or ribonucleosides. 2'-Deoxy-N4,5-dimethylcytidine is also a novel monophosphate nucleoside that has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug inhibits DNA synthesis by preventing the incorporation of diphosphate nucleotides into DNA during DNA replication. 2'-Deoxy-N4,5-dimethylcytidine is not active against RNA synthesis because it does not have any activity at this site.</p>Fórmula:C11H17N3O4Pureza:Min. 95%Peso molecular:255.27 g/mol2-Deoxycytidine 3',5'-diphosphate
CAS:<p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>Fórmula:C9H15N3O10P2Pureza:Min. 95%Peso molecular:387.18 g/molFialuridine 5'-monophosphate
CAS:Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.Fórmula:C9H11FIN2O8PPureza:Min. 95%Peso molecular:452.07 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG
<p>2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG is a modified nucleoside, which is synthetically prepared. It is an activator of DNA polymerase and has been shown to be active against human leukemia cells. 2'-Deoxy-5'-O-DMT-N2-isobutyryl Guanosine 3'-lcaa CPG has also been shown to inhibit the replication of the herpes simplex virus type 1 in vitro. The compound is a novel high quality nucleoside phosphoramidite that can be used as a building block in the synthesis of deoxyribonucleosides and modified nucleosides with novel chemical structures.</p>Pureza:Min. 95%Tert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate
CAS:Tert-Butyl 2-Phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is an antiviral agent that inhibits the replication of DNA and RNA. It is a phosphoramidate nucleoside analog and a novel compound that has been modified to improve its stability. Tert-butyl 2-phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is currently being investigated for use as a drug to treat HIV/AIDS. This compound has been shown to inhibit HIV protease by binding to the active site of the enzyme and preventing it from cutting the polypeptide chain into smaller pieces. Tert butyl 2 phenyl 4Fórmula:C25H27N3O5SPureza:Min. 95%Peso molecular:481.57 g/molCytidine hemisulfate salt
CAS:Cytidine hemisulfate salt is a postulated inhibitor of the blood group antigen. It inhibits the phosphatase activity of blood group-specific phosphatases, which may be caused by its specific inhibition of α-tocopherol and phenolphthalein. Cytidine hemisulfate salt has been shown to inhibit both adenylic and uridylic phosphatases, but does not inhibit other phosphatases. This drug is also an antigen that can stimulate B cells, which produce antibodies against it. Cytidine hemisulfate salt is found in DNA and RNA.Fórmula:C9H13N3O5H2SO4Pureza:Min. 95%Peso molecular:292.26 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å
<p>2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å is an anticancer drug that is used in the treatment of acute myeloid leukemia. This compound is a modified nucleoside. It has been shown to inhibit the growth of cultured cells and induce apoptosis by causing DNA damage. The anticancer properties of 2'-deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å are mediated by its inhibition of DNA synthesis, RNA synthesis, and protein synthesis.</p>Pureza:Min. 95%5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine
<p>5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine is a novel anticancer agent that has been shown to be active against leukemia, lymphoma and myeloma. The compound is a nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have antiviral activity in vitro against herpes simplex virus type 1 and type 2, influenza A virus and HIV. 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine can also inhibit protein synthesis by blocking the incorporation of amino acids into protein. This drug is synthesized from 3',5'-dideoxyuridine (dU) and fluoroacetyl chloride to produce 5'-O-p-anisoyl-3',5'-difluoroacetyl dU (ADUF). ADUF is then reacted with anisole to produce 5</p>Fórmula:C18H19FN2O6Pureza:Min. 95%Peso molecular:378.4 g/mol
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