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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3569 productos de "Nucleósidos"

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  • 2’-Deoxy-N2-DMF-2’-fluoroguanosine


    <p>Please enquire for more information about 2’-Deoxy-N2-DMF-2’-fluoroguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C13H17FN6O4
    Pureza:Min. 95%
    Peso molecular:340.31 g/mol

    Ref: 3D-NF183589

    50g
    2.324,00€
    100g
    4.330,00€
  • dG-MGO

    CAS:
    <p>Methylglyoxal (MGO) is a reactive byproduct formed by several metabolic precursors notably glycolysis. dG-MGO is therefore a useful marker to in monitoring various glycation pathways</p>
    Fórmula:C13H17N5O7
    Peso molecular:355.3 g/mol

    Ref: 3D-ND01157

    10mg
    2.640,00€
  • 3'-O-Methylcytidine 5'-triphosphate lithium salt

    CAS:
    <p>3'-O-Methylcytidine 5'-triphosphate lithium salt is an antiviral agent that inhibits the synthesis of RNA by inactivating the enzyme ribonuclease. The compound has been shown to be effective against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 3'-O-Methylcytidine 5'-triphosphate lithium salt is a novel nucleoside analogue that can be used as a phosphoramidite building block for DNA synthesis. It is also a high quality synthetic product with high purity and high purity.</p>
    Fórmula:C10H14N3O14P3·Li4
    Pureza:Min. 95%
    Peso molecular:520.92 g/mol

    Ref: 3D-NM46051

    1mg
    1.234,00€
    2mg
    2.005,00€
    5mg
    4.172,00€
    10mg
    6.953,00€
  • 2'-Amino-2'-deoxycytidine-5'-triphosphate

    CAS:
    <p>2'-Amino-2'-deoxycytidine-5'-triphosphate is an inhibitor of viral RNA polymerase. It is a nucleoside analogue that mimics the natural substrate for the enzyme, 2'-deoxycytidine-5'-triphosphate. This compound binds to the active site of viral RNA polymerases and blocks their ability to synthesize RNA. The compound has been shown to inhibit the replication of norovirus and HIV in cell culture. 2'-Amino-2'-deoxycytidine-5'-triphosphate binds to metal ions in the active site of the enzyme, which prevents its binding with the template strand and prevents elongation of RNA synthesis.</p>
    Fórmula:C9H17N4O13P3
    Pureza:Min. 95%
    Peso molecular:482.17 g/mol

    Ref: 3D-NA09399

    10mg
    668,00€
    25mg
    1.085,00€
    50mg
    1.627,00€
    100mg
    2.535,00€
  • Guanosine-2'(&3')-monophosphate disodium (mixed isomers)

    CAS:
    Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is a synthetic nucleoside with antiviral and anticancer properties. It has been shown to activate the transcription of DNA in vitro by binding to the promoter region, resulting in higher levels of RNA synthesis. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) has been shown to inhibit the replication of viruses, such as herpes simplex virus type 1 (HSV-1), and it may have potential use in cancer therapy. The drug is also used as a precursor for other antiviral drugs and antibiotics. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is available in high purity, high quality, and at low cost.
    Fórmula:C10H14N5O8P•2Na
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:407.18 g/mol

    Ref: 3D-NG57356

    25mg
    360,00€
    50mg
    475,00€
    100mg
    703,00€
    250mg
    1.163,00€
    500mg
    1.723,00€
  • 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    <p>7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and</p>
    Fórmula:C11H17N4O13P3·xNa
    Pureza:Min. 95%
    Peso molecular:506.19 g/mol

    Ref: 3D-ND157324

    1mg
    1.157,00€
    2mg
    1.960,00€
    5mg
    4.453,00€
    500µg
    745,00€
  • 5-Fluorouridine-5'-diphosphate sodium

    CAS:
    <p>5-Fluorouridine-5'-diphosphate sodium salt is a nucleoside analog that inhibits the synthesis of RNA and DNA. It is used to treat cancer, as well as opportunistic infections, such as cryptococcal disease. 5-Fluorouridine-5'-diphosphate sodium salt binds to the enzyme thymidylate synthase and prevents it from synthesizing dTMP, which is needed for DNA synthesis. This drug also has been shown to be effective against monoclonal antibodies in mice with cancer. 5-Fluorouridine-5'-diphosphate sodium salt may also be useful in gene therapy for cancer treatment. This drug can be taken up by cells where it is converted into uracil, which inhibits protein synthesis by competing with the natural substrate tRNA for binding sites on ribosomes.</p>
    Fórmula:C9H13FN2O12P2•Nax
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:423.16 g/mol

    Ref: 3D-NF31489

    100mg
    8.448,00€
  • 2'-O-Methylguanosine 5'-monophosphate sodium

    CAS:
    <p>2'-O-Methylguanosine 5'-monophosphate sodium is a nucleoside analog that has been shown to inhibit the growth of human cancer cells. It is a modified monophosphate nucleotide, which is synthesized by the chemical modification of guanosine with 2'-O-methylation at the 5' position and phosphorylation at the 3' position. This drug is not active against viruses and may be used as an anticancer agent. 2'-O-Methylguanosine 5'-monophosphate sodium has also been shown to be effective in treating hepatitis B virus infection. The drug may act as an antiviral agent by interfering with viral DNA synthesis, causing viral particles to aggregate, or by inhibiting viral DNA polymerase activity.</p>
    Pureza:Min. 95%

    Ref: 3D-NM182233

    1g
    1.987,00€
  • 3'-O-Methyladenosine 5'-triphosphate lithium salt

    CAS:
    <p>3'-O-Methyladenosine 5'-triphosphate lithium salt is a phosphoramidite that is used in the synthesis of DNA and RNA. This product has antiviral and anticancer properties. 3'-O-Methyladenosine 5'-triphosphate lithium salt is a novel nucleoside that is synthesized by modifying the phosphate group with a methyl group at the 3' position. It also has high purity, as well as high quality and modified nucleosides.</p>
    Fórmula:C11H14N5O13P3·Li4
    Pureza:Min. 95%
    Peso molecular:544.94 g/mol

    Ref: 3D-NM46050

    5mg
    853,00€
    10mg
    1.340,00€
    25mg
    2.719,00€
  • 5-Cyano-2'-deoxycytidine

    CAS:
    Nucleobase functionalised deoxynucleoside
    Fórmula:C10H12N4O4
    Pureza:Min. 95%
    Peso molecular:252.23 g/mol

    Ref: 3D-NC167225

    1g
    1.193,00€
    2g
    1.844,00€
    5g
    3.696,00€
  • 4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    <p>4-Thiothymidine-5'-triphosphate lithium salt - 100mM aqueous solution is thio-base modified thymidine nucleotide</p>
    Fórmula:C10H17N2O13P3S·xLi
    Pureza:Min. 95%
    Peso molecular:498.23 g/mol

    Ref: 3D-NT158272

    2mg
    944,00€
    5mg
    1.844,00€
    10mg
    2.867,00€
  • Lauroyl coenzyme A potassium salt

    CAS:
    <p>Lauroyl coenzyme A potassium salt is a potent inhibitor of fatty acid synthase. It has the ability to inhibit the enzyme activity of fatty acid synthase in vitro, which belongs to the class of irreversible inhibitors. Lauroyl coenzyme A potassium salt inhibits the synthesis of fatty acids by inhibiting the enzyme activity of fatty acid synthase. This inhibitor also reversibly inhibits other enzymes with a similar mechanism, such as acetyl-coenzyme A carboxylase and phosphatidate phosphohydrolase. The reaction mechanism can be understood through titration calorimetry studies, demonstrating that lauroyl coenzyme A potassium salt binds to the active site of these enzymes and blocks access to substrates. The binding affinity is higher for wild type strains than for mutant strains, which may be due to differences in protein structure or other factors. Lauroyl coenzyme A potassium salt has been shown to have no effect on wild-type strains but inhibits polymer</p>
    Fórmula:C33H55N7O17P3SK3
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:1,064.11 g/mol

    Ref: 3D-NL161093

    50mg
    1.952,00€
  • Thymidine 3'-monophosphate sodium salt

    CAS:
    <p>Thymidine 3'-monophosphate sodium salt (TMP) is a nucleoside that is involved in the synthesis of DNA. TMP has been shown to have minimal carcinogenic effects on the liver, with no effect on the rate of DNA synthesis or cell proliferation in vivo. It has been shown to be hepatotoxic and genotoxic in animal studies and can cause DNA strand breaks and chromosomal aberrations in liver cells. TMP also causes a specific adduct, crotonaldehyde, which is considered to be an indicator of hepatic injury. The detection method for this adduct uses gas chromatography-mass spectrometry, which identifies the presence of TMP by detecting its unique mass spectrum.</p>
    Fórmula:C10H15N2O8P•xNa
    Pureza:Min. 95%
    Forma y color:Powder

    Ref: 3D-NT156795

    1g
    4.697,00€
    50mg
    731,00€
    100mg
    1.065,00€
    250mg
    1.982,00€
    500mg
    3.112,00€
  • 2',3'-Dideoxy-3',5-difluorocytidine

    CAS:
    <p>2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.</p>
    Pureza:Min. 95%

    Ref: 3D-ND144806

    100mg
    10.033,00€
  • 2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite

    CAS:
    2'-O-tert-Butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-DMT-guanosine 3'-CE phosphoramidite is a synthetic nucleoside analog. The chemical name for this product is 2'-O-tert-butyldimethylsilyl-N-(tert-butylphenoxyacetyl)-5'-O-dimethoxytritylguanosine 3'-cyanoethylphosphoramidite. The molecular formula is C28H34N2O8PSi, and the molecular weight is 812.59 g/mol. This product has an EC Number of 61317 - CAS Number of 149989 - 68 - 4 and a melting point of 232°C (238°F). This compound can be used in the synthesis of oligonucleotides that are used to bind to RNA and
    Fórmula:C58H76N7O10PSi
    Pureza:Min. 95%
    Peso molecular:1,090.32 g/mol

    Ref: 3D-PB63474

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    208,00€
  • 2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite

    CAS:
    <p>2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It is synthesized from 2'-deoxy-5'-O-DMT-5-acetoxymethyluridine and 3'-chloroethyl phosphate. The compound has been shown to inhibit DNA, RNA, and protein synthesis in vitro, as well as to induce apoptosis in human cancer cell lines. 2'-Deoxy-5'-O-DMT-5-acetoxymethyluridine 3'-CE phosphoramidite is a modified nucleoside that can be used in the production of oligonucleotides for use in gene therapy.</p>
    Fórmula:C42H51N4O10P
    Pureza:Min. 95%
    Peso molecular:802.85 g/mol

    Ref: 3D-PD09125

    1g
    738,00€
    2g
    1.098,00€
    5g
    2.228,00€
    10g
    3.712,00€
  • 2'-Deoxy-5-methyl-isocytidine

    CAS:
    <p>2'-Deoxy-5-methyl-isocytidine is an analog of cytidine that is used in the synthesis of oligodeoxynucleotides. It has shown to be complementary to dsDNA and to inhibit hepatitis B virus replication in cell culture. 2'-Deoxy-5-methyl-isocytidine is synthesized by solid phase chemistry on a polystyrene support with monomers, depyrimidination, and purification by column chromatography. The chemical stability of this compound has been shown by its ability to withstand heating at 100°C for 10 minutes without decomposition.</p>
    Fórmula:C10H15N3O4
    Pureza:Min. 95%
    Peso molecular:241.26 g/mol

    Ref: 3D-ND76392

    1g
    1.952,00€
  • 2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-N4-(tert-butylphenoxyacetyl)-5'-O-DMT-cytidine 3'-CE phosphoramidite is a DNA synthesis reagent that is used in the preparation of oligonucleotides, in particular for the synthesis of 2'-deoxyribonucleosides. It has been shown to be an activator and to have anticancer, antiviral, and antimalarial properties. This compound is synthesized by reacting 5'-O-DMT cytidine with 2',3' epoxypropyltrichlorophosphite. The product is purified by silica gel column chromatography and recrystallization from ethanol followed by vacuum drying. CAS No. 149989-66-2</p>
    Fórmula:C57H76N5O10PSi
    Pureza:Min. 95%
    Peso molecular:1,050.3 g/mol

    Ref: 3D-PB63473

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    208,00€
  • 2,2'-Anhydro-L-thymidine

    CAS:
    <p>2,2'-Anhydro-L-thymidine is an antiviral, anticancer agent and a synthetic nucleoside. It is a monophosphate that was first synthesized in 1967 and has been used as a potential antiviral agent. 2,2'-Anhydro-L-thymidine has been shown to be effective against the herpes simplex virus type 1 (HSV1). However, it does not inhibit viral nucleic acid synthesis or viral protein synthesis. It also does not inhibit the growth of tumor cells in culture.</p>
    Fórmula:C10H12N2O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:240.21 g/mol

    Ref: 3D-NA07017

    50mg
    2.364,00€
    100mg
    3.940,00€
    250mg
    8.208,00€
  • 7-Deaza-2'-deoxy-7-ethynyladenosine

    CAS:
    <p>7-Deaza-2'-deoxy-7-ethynyladenosine is a fluorescent analog of adenosine that has been synthesized to be used as an antimicrobial agent. This compound has shown to be effective against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus and Escherichia coli. 7DDAE is also able to inhibit the growth of fungus and yeast, such as Candida albicans. This drug has been shown to have no cytotoxic effects on mammalian cells at concentrations up to 50 μM. 7DDAE has been found to be very photostable in solution, which means it does not degrade when exposed to light.</p>
    Fórmula:C13H14N4O3
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:274.28 g/mol

    Ref: 3D-ND44812

    10mg
    6.838,00€