Nucleósidos
Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.
Se han encontrado 3569 productos de "Nucleósidos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
5-Chloro-2'-deoxycytidine
CAS:5-Chloro-2'-deoxycytidine (5-Cl-dC) is a nucleoside analog that inhibits DNA synthesis by blocking the action of thymidylate synthase. It can be used in animal models to study bowel diseases, such as ulcerative colitis and Crohn's disease. 5-Cl-dC has been shown to be effective in treating the effects of radiation and chemical toxicity in HL60 cells, a type of human leukemia cell line. 5-Cl-dC has also been shown to enhance the cytotoxicity of eosinophil peroxidase, which is an enzyme that may be involved in the pathogenesis of asthma. This drug is currently being evaluated for its safety and efficacy in clinical trials involving patients with myelodysplastic syndrome or acute myeloid leukemia who are at risk for developing leukemia.
Fórmula:C9H12CIN3O4Pureza:Min. 95%Forma y color:PowderPeso molecular:261.67 g/molb-Nicotinamide mononucleotide
CAS:b-Nicotinamide mononucleotide, or NMN, is a precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all living cells that is essential for various metabolic processes. NAD+ is involved in critical functions such as DNA repair, gene expression, and cellular stress responses.Fórmula:C11H15N2O8PPureza:Min. 95 Area-%Forma y color:PowderPeso molecular:334.22 g/mol2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
CAS:Amidite designed to withstand prolonged exposure to strongly alkaline conditions during heating with ammonium hydroxide solution.Fórmula:C48H54N7O8PPureza:Min. 95%Forma y color:PowderPeso molecular:887.98 g/molAdenosine 5'-diphosphate monosodium salt
CAS:Used for energy storage and in nucleic acid metabolismFórmula:C10H14N5NaO10P2Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:449.18 g/mol1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a chemically modified nucleoside that contains a fluorinated sugar moiety and a thymine base, with a dimethoxytrityl (DMT) protecting group on the 5'-hydroxyl of the sugar.Fórmula:C31H31FN2O7Pureza:Min. 95%Peso molecular:562.6 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an antiviral agent that belongs to the class of monophosphate deoxyribonucleosides. It is a novel compound that has been shown to be an activator of high purity and quality. 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is synthesized from modified ribonucleosides and phosphoramidites. The antiviral activity of this drug against DNA viruses (e.g., herpes, adenovirus) and RNA viruses (e.g., influenza virus) has been shown in vitro and in vivo. In addition, 1-(2-C-Methyl-b--D--ribofuranosyl)-5--nitropyridine--2(1H)--Pureza:Min. 95%1-Methylpseudouridine
CAS:1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).Fórmula:C10H14N2O6Pureza:Min. 98.0 Area-%Peso molecular:258.23 g/molRef: 3D-M-4320
1gA consultar5gA consultar250mgA consultar500mgA consultar2500mgA consultar-Unit-ggA consultar2-Methylthio-N6-isopentenyladenosine
CAS:A nucleoside analogue of adenosine that arises from post-transcriptional modification. In humans, this is mediated by the enzyme CDK5RAP1 in mitochondrial transfer RNA (tRNA) at amino acid 37. Deficiency for this modification, for example due to CDK5RAP1 deficiency, leads to impaired mitochondrial protein synthesis. This has implications for mitochondrial diseases, as well as cancer, type II diabetes and vitiligo. Synthetic ms2i6A can be used to raise monoclonal antibodies against this nucleotide in vivo.Fórmula:C16H23N5O4SPureza:Min. 95%Forma y color:White PowderPeso molecular:381.45 g/molTricyclic nucleoside phosphate
CAS:Akt activation inhibitor
Fórmula:C13H17N6O7PPureza:Min. 95%Peso molecular:400.28 g/molBucladesine calcium salt
CAS:Protein kinase A inhibitor; cAMP agonistFórmula:C18H24N5O8PCaPureza:Min. 95%Forma y color:PowderPeso molecular:489.42 g/mol5'-Deoxy-5'-fluorothymidine
CAS:5'-Deoxy-5'-fluorothymidine is a cytotoxic agent that inhibits the synthesis of DNA by binding to the enzyme thymidylate synthase and preventing the formation of thymine nucleotide. 5'-Deoxy-5'-fluorothymidine has shown to be effective against herpes simplex virus, murine bone, and tissue culture cells. This drug also inhibits cellular proliferation in vitro and can be used in chemotherapy treatment. 5'-Deoxy-5'-fluorothymidine is synthesized from guanine by an enzyme called deoxyguanosine kinase. The biosynthesis of this drug involves two steps: conversion of guanine to xanthosine monophosphate (XMP) and conversion of XMP to 5'-deoxy-5'-fluorothymidine (dFTP).Fórmula:C10H13FN2O4Pureza:Min. 95%Peso molecular:244.22 g/molN2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine
N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a modified nucleotide that has been shown to be an activator of the protein kinase C and may have anticancer and antiviral properties. N2-Isobutyryl-2'-deoxy-5'-O-pixylguanosine is a synthetic nucleoside that is structurally similar to ribonucleosides and deoxyribonucleosides, but contains a modified base. The nucleotide is activated by phosphorylation and then undergoes hydrolysis in the cell to form diphosphate. This product has CAS No. 125965-04-3, purity at 99%, and high quality.Fórmula:C33H31N5O6Pureza:Min. 95%Peso molecular:593.64 g/mol3’-Deoxy-3’C-methyl-5-methyluridine
CAS:3’-Deoxy-3’C-methyl-5-methyluridine is a novel and efficient phosphoramidite monophosphate, which can be used in the synthesis of DNA. This product has antiviral activity against HIV and some other viruses. The phosphoramidite is modified with a diphosphate group, which increases the efficiency of DNA synthesis. 3’-Deoxy-3’C-methyl-5-methyluridine is synthesized by modifying 5′ position with a C6 methylaminomethyl group and coupling with the 3′ deoxynucleoside.Pureza:Min. 95%2',3'-Di-O-acetyladenoside
CAS:2',3'-Di-O-acetyladenoside is a nucleoside for use in research applicationsFórmula:C14H17N5O6Pureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:351.31 g/mol3-Methyl-2-nitropyridine
CAS:3-Methyl-2-nitropyridine is a high yield byproduct of formamide, which can be activated to form an intermediate for the synthesis of nucleosides. The kinetics and labeling of this intermediate were studied using a transfer experiment. 3-Methyl-2-nitropyridine is acidic, with a pKa value of 3.6, and is reactive towards nucleophiles. It is also catalytic, yielding methyl groups and dioxane as products when heated at temperatures between 180°C and 220°C. In addition, it undergoes nucleophilic substitutions at methoxy groups.
Fórmula:C6H6N2O2Pureza:Min. 95%Forma y color:PowderPeso molecular:138.12 g/mol2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt
CAS:2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt is a novel antiviral and anticancer compound. It is an analogue of adenosine, which inhibits the synthesis of viral RNA and DNA. This compound can also be used to treat certain types of cancer. 2'-O-(N-Methylanthraniloyl)-3'-deoxy-adenosine-5'-triphosphate triethylammonium salt is chemically synthesized by reacting anthranilic acid with 3',5'-dideoxyadenosine 5' triphosphoric acid.Fórmula:C18H23N6O13P3Pureza:Min. 95%Peso molecular:624.33 g/molN4-Benzoyl-2'-deoxy-5'-O-tritylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine is a nucleoside analog that is used as an antiviral agent. It inhibits DNA synthesis by inhibiting the enzyme DNA polymerase, which is essential for the replication of viral and cellular DNA. N4-Benzoyl-2'-deoxy-5'-O-tritylcytidine also has anticancer activity, which may be due to its ability to inhibit ribonucleotide reductase and thereby block the production of RNA.Fórmula:C35H31N3O5Pureza:Min. 95%Peso molecular:573.65 g/molN4-Benzoyl-2'-deoxy-5'-O-pixylcytidine
CAS:N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine is a novel nucleoside that is structurally related to cytidine. It is synthesized from 2'-deoxycytidine monophosphate and 4-benzoylpixyl chloride. N4-Benzoyl-2'-deoxy-5'-O-pixylcytidine has antiviral, antiangiogenic and anticancer properties, as well as the ability to inhibit the replication of DNA in cells. This compound can be used for synthesis of phosphoramidites, which are used in the production of oligonucleotides.Fórmula:C35H29N3O6Pureza:Min. 95%Peso molecular:587.64 g/mol4’,5’-Didehydro-5’-deoxy-5-methyluridine
CAS:4’,5’-Didehydro-5’-deoxy-5-methyluridine is a monophosphate nucleoside that is used as an antiviral agent. It has been shown to be active in the treatment of HIV and hepatitis B. 4’,5’-Didehydro-5’-deoxy-5-methyluridine also has anticancer properties and has been shown to inhibit cell proliferation in vitro by interfering with DNA synthesis. This product is an intermediate for the synthesis of other nucleosides and phosphoramidites.Pureza:Min. 95%N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.Fórmula:C53H66N7O8PSiPureza:Min. 95%Forma y color:PowderPeso molecular:988.19 g/mol
