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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3569 productos de "Nucleósidos"

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  • 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine


    6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydroxyamino-1H pyrazolo[3,4 d]pyrimidine can be used in the synthesis of phosphoramidites for DNA synthesis and for the production of monophosphate nucleotides. The compound has been shown to inhibit the growth of cells in culture that are resistant to other antiinfectives such as erythromycin and chloramphenicol.
    Pureza:Min. 95%

    Ref: 3D-NA162941

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  • N4-Acetylcytidine

    CAS:
    N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.
    Fórmula:C11H15N3O6
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:285.25 g/mol

    Ref: 3D-NA05753

    1kg
    4.665,00€
    50g
    485,00€
    100g
    738,00€
    250g
    1.622,00€
    500g
    2.686,00€
  • 3’-Deoxy-3’-fluoro-N6-hydroxyadenosine

    CAS:
    3’-Deoxy-3’-fluoro-N6-hydroxyadenosine (3'-DF) is an antiviral nucleoside that inhibits viral DNA synthesis and has shown cytotoxic effects in human cancer cells. 3'-DF is a novel chemical compound that was first synthesized in 1994. It is a nucleotide analog that is structurally related to adenosine, with the exception of the fluoro atom at position 6 on the ribose sugar. 3'-DF inhibits DNA polymerase and RNA polymerase by competitively binding to the ribonucleotide reductase enzyme, inhibiting the production of new RNA and DNA molecules. This compound also has been shown to inhibit protein synthesis in cancer cells without affecting normal cells.
    Pureza:Min. 95%

    Ref: 3D-ND162841

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  • 5-Fluoro-4’-C-methyluridine

    CAS:
    5-Fluoro-4’-C-methyluridine is a novel antiviral agent that is structurally related to the nucleoside analogue cytidine. It has been shown to be an activator of DNA polymerase, which may contribute to its antiviral activity. 5-Fluoro-4’-C-methyluridine has been shown to inhibit the growth of cancer cells by modifying the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Fluoro-4’-C-methyluridine has also been shown to have anticancer effects, as it inhibits cell proliferation and induces apoptosis.
    Pureza:Min. 95%

    Ref: 3D-NF163130

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  • Isocytidine triphosphate triethylamine

    CAS:
    Isocytidine triphosphate triethylamine salt is a nucleoside that has been modified to include an amino group. It is a monophosphate, which means it contains one phosphate group. Isocytidine triphosphate triethylamine salt has shown anticancer properties as it inhibits the synthesis of DNA and RNA. This compound also prevents the activation of transcription factors, such as NF-κB, that are important in cancer cell proliferation.
    Fórmula:C9H16N3O14P3•(C6H15N)x
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:483.15 g/mol

    Ref: 3D-NI61633

    1mg
    258,00€
    2mg
    378,00€
    5mg
    673,00€
    10mg
    1.011,00€
    25mg
    1.764,00€
  • 2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine

    CAS:
    Intermediate in the synthesis of nelarabine
    Fórmula:C10H12ClN5O4
    Pureza:Min. 97 Area-%
    Forma y color:Off-White Powder
    Peso molecular:301.69 g/mol

    Ref: 3D-NA04201

    10g
    236,00€
    25g
    370,00€
    50g
    518,00€
    100g
    756,00€
    250g
    1.259,00€
  • 5'-O-MMT-thymidine 3'-CE phosphoramidite

    CAS:

    5'-O-MMT-thymidine 3'-CE phosphoramidite is a novel anticancer drug that is modified from the natural nucleoside thymidine. It has been shown to inhibit the activity of DNA polymerase, preventing DNA synthesis and replication. It also inhibits viral DNA replication, including HIV and herpes simplex virus type-1 (HSV-1). 5'-O-MMT-thymidine 3'-CE phosphoramidite has antiviral properties against HIV and HSV-1. This nucleoside is synthesized by reacting 5'-O-methyl cytidylic acid with an activated phosphite in the presence of triethylamine in dichloromethane. The product is purified by column chromatography on silica gel and recrystallization from acetonitrile.

    Fórmula:C39H47N4O7P
    Pureza:Min. 95%
    Peso molecular:714.81 g/mol

    Ref: 3D-PM09155

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  • 5'-O-DMT-thymidine 3'-succinyl CPG 500 Å


    5'-O-DMT-thymidine 3'-succinyl CPG 500 Å is a high purity, novel nucleoside analog. It is a modified nucleoside that has been synthesized by using a diphosphate and monophosphate to replace the phosphate triester on the 5' position of the sugar moiety. This product can be used as an anticancer or antiviral agent.

    Pureza:Min. 95%
    Forma y color:White Powder

    Ref: 3D-ND11614

    1g
    258,00€
    2g
    376,00€
    5g
    598,00€
    10g
    1.019,00€
  • N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite


    N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel ribonucleotide with high purity and high quality. It is an activator of DNA synthesis and can be used in the synthesis of DNA, monophosphate, and diphosphate. N2-DMF-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is used for the preparation of anticancer drugs, antiviral agents, and other nucleosides.
    Fórmula:C44H55N8O8P
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:854.95 g/mol

    Ref: 3D-PD09181

    1g
    483,00€
    250mg
    200,00€
    500mg
    336,00€
  • 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one

    CAS:
    6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a novel nucleoside that has been shown to have anticancer and antiviral properties. In vitro studies have shown the compound to activate both DNA and RNA synthesis in cells. The compound also inhibits the replication of HIV viruses. 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is synthesized from ribonucleosides or deoxyribonucleosides through phosphoramidite chemistry. This product is available in high purity and high quality.
    Fórmula:C11H15N3O5
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:269.25 g/mol

    Ref: 3D-ND145587

    10mg
    307,00€
    20mg
    461,00€
    50mg
    713,00€
    100mg
    1.068,00€
    250mg
    2.232,00€
  • 2'-Deoxy-5'-DMT-5-(prop-2-yn-1-ylcarbamoyl)uridine 3'-CE phosphoramidite


    2'-Deoxy-5'-DMT-5-(prop-2-yn-1-ylcarbamoyl)uridine 3'-CE phosphoramidite is a diphosphate nucleoside that is used in the synthesis of DNA. It has been modified with an acetyl group at the 2' position and a propargylamine group at the 5' position. This modification improves its stability to hydrolysis by esterases and also increases binding affinity for cationic lipids. The purified material is suitable for use in a variety of DNA syntheses, including PCR amplification, gene cloning, and site-directed mutagenesis.
    Pureza:Min. 95%

    Ref: 3D-PD138058

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  • N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine

    CAS:

    N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.

    Fórmula:C44H49N5O7Si
    Pureza:Min. 97 Area-%
    Forma y color:Powder
    Peso molecular:787.97 g/mol

    Ref: 3D-NB15297

    5g
    338,00€
    10g
    499,00€
    25g
    829,00€
    50g
    1.202,00€
    100g
    1.802,00€
  • 3’-b-Amino-2’,3-dideoxy uridine

    CAS:
    3’-b-Amino-2’,3-dideoxy uridine is an activator nucleoside that is a novel therapeutic agent for viral infections and cancer. It has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), as well as anticancer activity against human breast adenocarcinoma cells. 3’-b-Amino-2’,3-dideoxy uridine is a modified nucleoside with antiviral and anticancer properties. This drug has been shown to inhibit HSV-1 replication by interfering with the synthesis of viral DNA. 3’-b-Amino-2’,3-dideoxy uridine also inhibits the proliferation of human breast adenocarcinoma cells by inhibiting ribonucleotide reductase.
    Fórmula:C9H13N3O4
    Pureza:Min. 95%
    Peso molecular:227.22 g/mol

    Ref: 3D-NA144655

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  • Uridine-5'-triphosphate trisodium salt

    CAS:
    P2Y receptor agonist; precursor in RNA biosynthesisÂ
    Fórmula:C9H12N2Na3O15P3
    Pureza:(31P Nmr) Min. 95 Area-%
    Forma y color:White Powder
    Peso molecular:550.09 g/mol

    Ref: 3D-NU03863

    2g
    343,00€
    5g
    528,00€
    10g
    738,00€
    25g
    1.285,00€
    50g
    1.901,00€
  • N6-Benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine


    The N6-benzoyl-2'-chloro-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that is a potent inhibitor of the human immunodeficiency virus type 1 (HIV-1) and has been shown to be effective against cancer. It is a phosphoramidite nucleoside with high purity and high quality, which can be used as an antiviral agent or an anticancer agent. The chemical name for this compound is 2'-(N6-Benzoyl)-2'-deoxyadenosine 5'-O-(DMT). This product is also known as NBDT, and it has been modified by changing the ribose sugar to DMT. NBDT inhibits viral replication by preventing the formation of DNA from RNA in the reverse transcription process. This process requires two enzymes: HIV reverse transcriptase and DNA polymerase α. The first enzyme, HIV reverse transcriptase,
    Pureza:Min. 95%

    Ref: 3D-NB144454

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  • 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine

    CAS:
    Please enquire for more information about 3’,5’-Di-O-benzoyl-2’-deoxy-2’-fluoro-5-trifluoromethyl-arabinouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Pureza:Min. 95%

    Ref: 3D-FD144797

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  • 1-(Arabinofuranosyl)-5-azidomethyluracil

    CAS:
    1-(Arabinofuranosyl)-5-azidomethyluracil (AFAU) is a novel nucleoside that is synthesized by the reaction of 5-azido-1-(2'-deoxyribofuranosyl) uracil with phosphoramidite. The synthesis of this nucleoside has been used as a model for the synthesis of other deoxyribonucleosides. AFAU is an activator of ribonucleotide reductase and has shown activity against DNA and RNA viruses, such as influenza virus, herpes simplex virus type 1, and human immunodeficiency virus type 1.
    Pureza:Min. 95%

    Ref: 3D-NA162994

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  • 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine


    9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is a novel nucleoside that has been synthesized by the phosphoramidite method. It is a monophosphate, which can be activated to yield an anticancer agent. 9-(5'-tert-Butyldiphenylsilyl-2'-deoxy-b-D-xylofuranosyl)guanine is chemically modified with a silyl group at the 5' position of the sugar moiety and a tertiary butyldiphenylsilyl group at the 2' position of the sugar moiety. It has been shown to inhibit DNA synthesis and viral replication, as well as to have antiangiogenic activity.
    Pureza:Min. 95%

    Ref: 3D-NB145599

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  • S-Adenosylmethione-1,4-butanedisulfonate

    CAS:
    S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.
    Fórmula:C42H74N12O28S8
    Pureza:Min. 95 Area-%
    Forma y color:White Powder
    Peso molecular:1,451.63 g/mol

    Ref: 3D-NA58198

    10g
    275,00€
    25g
    459,00€
    50g
    616,00€
    100g
    896,00€
    250g
    1.516,00€
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite


    2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.
    Pureza:Min. 95%

    Ref: 3D-PB170565

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