Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 191 productos para "Sistema complementario".
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Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Forma y color:SolidPeso molecular:2593.02C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Fórmula:C37H62F3N13O12Pureza:99.92%Forma y color:White SolidPeso molecular:937.96C5a Anaphylatoxin (human)
CAS:C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFórmula:C350H578N108O107S8Pureza:98%Forma y color:SolidPeso molecular:8267.51Factor B-IN-5
CAS:Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Fórmula:C27H32N2O4Pureza:99.71%Forma y color:White SolidPeso molecular:448.55PMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Fórmula:C45H62N10O6Pureza:98%Forma y color:SolidPeso molecular:839.04ATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Fórmula:C42H62F3N11O11Pureza:98%Forma y color:SolidPeso molecular:954PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Fórmula:C71H123N19O21S2Forma y color:SolidPeso molecular:1642.98Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Fórmula:(C2H4O)nC170H248N50O47S4·xC2H4O2Pureza:97.10%Forma y color:Odour SolidPeso molecular:1501.7tLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Fórmula:C31H59N15O10SForma y color:SolidPeso molecular:833.96Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Fórmula:C68H100F3N23O19S2Forma y color:SolidPeso molecular:1664.79C5a Receptor agonist, mouse, human
CAS:C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as anFórmula:C44H72N10O7Pureza:98%Forma y color:SolidPeso molecular:853.11ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Forma y color:SolidPeso molecular:120702.76Omoprubart
CAS:Omoprubart is an anti-C5 humanized monoclonal antibody blocking C5 cleavage and MAC formation (EC50 = 3.473 ng/mL) for PNH and complement research.Peso molecular:~148 kDaJPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Fórmula:C49H63FN10O9Forma y color:SolidPeso molecular:955.0845PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Fórmula:C71H123N19O21S2·xC2HF3O2Forma y color:SolidFactor B-IN-1
CAS:Factor B-IN-1 is a Factor B inhibitor.Fórmula:C19H16N4O2Forma y color:SolidPeso molecular:332.3559Certepetide
CAS:Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Fórmula:C37H60N14O14S2Forma y color:SolidPeso molecular:989.088PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Forma y color:SolidPeso molecular:896.09TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Fórmula:C107H170N40O26Pureza:98%Forma y color:SolidPeso molecular:2432.75BM213
CAS:BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Fórmula:C43H70N12O10Pureza:98%Forma y color:SolidPeso molecular:915.0903
