Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 178 productos para "Sistema complementario".
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tLyP-1 peptide
CAS:tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Fórmula:C31H59N15O10SForma y color:SolidPeso molecular:833.96C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Fórmula:C37H62F3N13O12Pureza:99.92%Forma y color:White SolidPeso molecular:937.96TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Fórmula:C107H170N40O26Pureza:98%Forma y color:SolidPeso molecular:2432.75Anti-GC1q R/C1QBP Antibody (60.11)
Anti-GC1q R/C1QBP Antibody (60.11) is a mouse IgG1, κ chimeric antibody designed to target human GC1q R/C1QBP. The recommended isotype control for this antibody is Mouse IgG1 kappa, Isotype Control.Forma y color:Odour LiquidComplement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFórmula:C22H20F2N6OPureza:97.77%Forma y color:Yellow SolidPeso molecular:422.43ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Forma y color:SolidPeso molecular:120702.76Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Forma y color:SolidPeso molecular:2593.02Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Forma y color:Odour SolidPMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Fórmula:C45H62N10O6Pureza:98%Forma y color:SolidPeso molecular:839.04L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Fórmula:C38H64N8O13Forma y color:SolidPeso molecular:840.973ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Forma y color:Odour LiquidATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Fórmula:C42H62F3N11O11Pureza:98%Forma y color:SolidPeso molecular:954PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.Fórmula:C47H63F3N10O8Forma y color:SolidPeso molecular:953.06POT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Fórmula:C74H103F3N22O20S2Forma y color:SolidPeso molecular:1741.87Campneoside II
CAS:Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Fórmula:C29H36O16Forma y color:SolidPeso molecular:640.59Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Fórmula:C29H28BrN7O3Forma y color:SolidPeso molecular:602.493PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Forma y color:SolidPeso molecular:896.09JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Fórmula:C49H63FN10O9Forma y color:SolidPeso molecular:955.08AMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Fórmula:C83H117N23O18S2Pureza:98%Forma y color:SolidPeso molecular:1789.11Certepetide
CAS:Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Fórmula:C37H60N14O14S2Forma y color:SolidPeso molecular:989.09
