Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 191 productos para "Sistema complementario".
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L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Fórmula:C38H64N8O13Forma y color:SolidPeso molecular:840.973C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Fórmula:C37H62F3N13O12Pureza:99.92%Forma y color:White SolidPeso molecular:937.96Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Fórmula:C128H190N24O33Forma y color:SolidPeso molecular:2593.02PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Forma y color:SolidPeso molecular:896.09PIC1 PA
CAS:PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Fórmula:C71H123N19O21S2Forma y color:SolidPeso molecular:1642.98TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Fórmula:C107H170N40O26Pureza:98%Forma y color:SolidPeso molecular:2432.75AMY-101 TFA
CAS:AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9Fórmula:C85H118F3N23O20S2Pureza:98.79% - 99.99%Forma y color:SolidPeso molecular:1903.11Izastobart
CAS:Izastobart is a monoclonal antibody of the HumanIgG1λ2 type, targeting C5AR1. The isotype control for Izastobart is HumanIgG1lambda2, Isotype Control.Pureza:95%Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Fórmula:(C2H4O)nC170H248N50O47S4·xC2H4O2Pureza:97.10%Forma y color:Odour SolidPeso molecular:1501.7Complement C1s-IN-1
CAS:Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFórmula:C22H20F2N6OPureza:97.77% - >99.99%Forma y color:Yellow SolidPeso molecular:422.43Complement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Forma y color:Lyophilized PowderPeso molecular:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Forma y color:Lyophilized PowderPeso molecular:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.MASP2 Protein, Human, Recombinant (His)
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.Forma y color:Lyophilized PowderPeso molecular:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.Complement C3a Protein, Mouse, Recombinant
Complement C3a Protein, Mouse, Recombinant is expressed in E.Pureza:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)Forma y color:Lyophilized PowderPeso molecular:9 KDa (reducing condition)Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Forma y color:Lyophilized PowderPeso molecular:31.10 kDa (predicted); 43-53 kDa (due to glycosylation)Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.Forma y color:Lyophilized PowderPeso molecular:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.C1QBP Protein, Mouse, Recombinant (His)
C1QBP Protein, Mouse, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:24.7 kDa (predicted); 32 kDa (reducing conditions)MASP2 Protein, Rat, Recombinant (E. coli, His)
MASP2 Protein, Rat, Recombinant (E.Pureza:> 95% as determined by Tris-Bis PAGE - > 95% as determined by Tris-Bis PAGEForma y color:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.C1s Protein, Human, Recombinant (His)
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.Forma y color:Lyophilized PowderPeso molecular:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His) is expressed in HEK293 Cells. The accession number is P01027-1.Forma y color:Lyophilized PowderPeso molecular:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)
