Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 178 productos para "Sistema complementario".
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C3a 70-77 2TFA(63555-63-5(free base))
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.Fórmula:C39H63N13O14Pureza:>99.99%Forma y color:SolidPeso molecular:1052.00Compstatin control peptide acetate
CAS:Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.Fórmula:C68H105N23O19Pureza:99.96%Forma y color:Odour SolidPeso molecular:1548.70TLQP 21 acetate
TLQP 21 acetate: Agonist for C3aR1, EC50 - 10.3 μM (mouse), 68.8 μM (human); VGF-derived with endo/extraendocrine traits.Fórmula:C109H174N40O28Pureza:99.99%Forma y color:SolidPeso molecular:2492.8LEP(116-130)(mouse)TFA(258276-95-8 free base)
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.Fórmula:C66H110F3N19O26SPureza:99.93%Forma y color:SolidPeso molecular:1674.77Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Forma y color:White SolidPeso molecular:421.49Eculizumab
CAS:Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Pureza:98.20%Forma y color:LiquidPeso molecular:145.74 kDaADH-503
CAS:ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.Fórmula:C27H28N2O5S2Pureza:99.03% - >99.99%Forma y color:SolidPeso molecular:524.7Ref: TM-T7776
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg75,00€25mg120,00€50mg178,00€100mg259,00€200mg384,00€BCX 1470 methanesulfonate
CAS:BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).Fórmula:C15H14N2O5S3Forma y color:SolidPeso molecular:398.48Danicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Fórmula:C26H23BrFN7O3Pureza:99.94%Forma y color:SolidPeso molecular:580.41Ref: TM-T8509
1mg90,00€2mg129,00€5mg203,00€1mL*10mM (DMSO)260,00€10mg310,00€25mg527,00€50mg755,00€100mg1.044,00€Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Fórmula:C27H24BrN7O3Pureza:99.53%Forma y color:SolidPeso molecular:574.43Ref: TM-T38332
1mg105,00€5mg241,00€1mL*10mM (DMSO)299,00€10mg360,00€25mg637,00€50mg900,00€100mg1.170,00€200mg1.584,00€JR14a
CAS:JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Fórmula:C25H26Cl2N4O3SPureza:99.76% - 99.96%Forma y color:SolidPeso molecular:533.47Compstatin
CAS:Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.Fórmula:C66H99N23O17S2Pureza:>99.99%Forma y color:SolidPeso molecular:1550.77Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Fórmula:C25H31ClN2O4Pureza:98.89% - 99.89%Forma y color:Gray SolidPeso molecular:458.98Ref: TM-T9189
1mg54,00€2mg77,00€5mg114,00€1mL*10mM (DMSO)114,00€10mg185,00€25mg334,00€50mg558,00€100mg928,00€200mg1.251,00€PMX 53 acetate(219639-75-5 free base)
CAS:PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50Fórmula:C49H69N11O9Pureza:99.91%Forma y color:SolidPeso molecular:956.16Ref: TM-TP2334
1mg105,00€5mg233,00€10mg344,00€1mL*10mM (DMSO)359,00€25mg532,00€50mg735,00€100mg982,00€200mg1.333,00€Complement C5a Protein, Human, Recombinant
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E.Pureza:SDS-PAGE: 94.9%; SEC-HPLC: 93.5%Forma y color:Lyophilized PowderPeso molecular:8.3 kDa (predicted); 8.3 kDa (reducing conditions)AMY-101 acetate
AMY-101 acetate (Cp40 acetate) is a peptide, an inhibitor of C3 Complement in gingivitis and periodontitis, reduces inflammation and lowers MMP-8 and MMP-9.Fórmula:C85H121N23O20S2Pureza:98.80% - 99.98%Forma y color:SolidPeso molecular:1849.14C1QA Protein, Mouse, Recombinant (E. coli, His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Pureza:98% - > 85% as determined by SDS-PAGEForma y color:Lyophilized PowderPeso molecular:29.1 kDa (predicted)Complement factor B Protein, Mouse, Recombinant (His)
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.Forma y color:Lyophilized PowderPeso molecular:87.0 kDa (predicted)Ref: TM-TMPH-02607
5µg106,00€10µg171,00€20µg276,00€50µg418,00€100µg566,00€200µg875,00€500µg1.554,00€1mg2.350,00€Complement C8a Protein, Human, Recombinant (His)
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli.Forma y color:Lyophilized PowderPeso molecular:65.8 kDa (predicted)Ref: TM-TMPH-01132
5µg93,00€10µg133,00€20µg213,00€50µg323,00€100µg442,00€200µg680,00€500µg1.198,00€1mg1.873,00€Complement C8b Protein, Human, Recombinant (His)
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane ofForma y color:Lyophilized PowderPeso molecular:67.0 kDa (predicted)Ref: TM-TMPH-01133
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€
