Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 156 productos de "Sistema complementario"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
C1QA Protein, Human, Recombinant (His & Myc)
<p>C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.</p>Forma y color:Lyophilized PowderPeso molecular:30.7 kDa (predicted)C5AR1 Protein-VLP, Human, Recombinant (His)
<p>Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.</p>Forma y color:Lyophilized PowderPeso molecular:41.1 kDa (predicted)Properdin Protein, Mouse, Recombinant (His)
<p>A positive regulator of the alternate pathway of complement.</p>Forma y color:Lyophilized PowderPeso molecular:51.9 kDa (predicted)C5AR1 Protein, Mouse, Recombinant (MBP & His-Avi), Biotinylated
<p>Expression system: E. coli<br>Length: 306-351, Partial<br>Activity: Not Tested</p>Forma y color:Lyophilized PowderPeso molecular:52.8 kDa (Predicted)Complement C8g Protein, Human, Recombinant (His)
<p>C8 is a constituent of the membrane attack complex.</p>Pureza:95%Forma y color:Lyophilized PowderPeso molecular:26.4 kDa (predicted)CR1 Protein, Human, Recombinant
<p>Expression system: E. coli<br>Length: 41-234, Partial<br>Activity: Not Tested</p>Forma y color:Lyophilized PowderPeso molecular:21.6 kDa (Predicted)C1SB Protein, Mouse, Recombinant (His & Myc)
<p>C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system.</p>Forma y color:Lyophilized PowderPeso molecular:82.4 kDa (predicted)C1QA Protein, Mouse, Recombinant (His)
<p>C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.</p>Pureza:90% - 92%Forma y color:Lyophilized PowderPeso molecular:25.6 kDa (predicted)Complement C3 Protein, Bovine, Recombinant (His & SUMO)
<p>Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:39.5 kDa (predicted)Complement factor D Protein, Rat, Recombinant (His)
<p>Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate</p>Forma y color:Lyophilized PowderPeso molecular:27.8 kDa (predicted)Empasiprubart
CAS:<p>Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.</p>Pureza:95%Forma y color:LiquidCrovalimab
CAS:<p>Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).</p>Pureza:95%Forma y color:LiquidGefurulimab
CAS:<p>Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.</p>Forma y color:LiquidRiliprubart
CAS:<p>Riliprubart (SAR445088) is a humanized monoclonal antibody that acts as an anti-C1s inhibitor in the proximal part of the classical complement system. It selectively targets activated C1s, inhibiting its enzymatic activity on substrates C4 and C2, thereby preventing the formation of the classical pathway C3 convertase, C4b2a [1].</p>Pureza:95% - 95%Forma y color:LiquidIsocyclosporin A
CAS:<p>Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.</p>Fórmula:C62H111N11O12Forma y color:SolidPeso molecular:1202.61C5aR-IN-2
CAS:<p>C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.</p>Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73BCX 1470
CAS:<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Fórmula:C14H10N2O2S2Pureza:98%Forma y color:SolidPeso molecular:302.37NRP1 antagonist 2
CAS:<p>NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.</p>Fórmula:C20H17ClN6OS2Forma y color:SolidPeso molecular:456.97FD-IN-1
CAS:<p>FD-IN-1: Factor D inhibitor, IC50=12 nM; blocks FXIa, Tryptase β2 (IC50s: 7.7 μM, 6.5 μM); key in innate immunity.</p>Fórmula:C23H23NO4Forma y color:SolidPeso molecular:377.43EG00229
CAS:<p>EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.</p>Fórmula:C19H20F3N7O7S3Pureza:98.23%Forma y color:SolidPeso molecular:611.6
