Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 191 productos para "Sistema complementario".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
C5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Fórmula:C14H10N2O2S2Pureza:98%Forma y color:SolidPeso molecular:302.37Anti-Human Complement Factor B Antibody
Anti-Complement Factor B Antibody is a potent inhibitory antibody targeting complement factor B. Anti-Complement Factor B Antibody demonstrates the capacity to suppress complement-mediated inflammatory responses and provides essential utility for researching alternative pathway-driven immune disorders.Peso molecular:145.59 kDa (Predicted)Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Fórmula:C62H111N11O12Forma y color:SolidPeso molecular:1202.6112NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Fórmula:C20H17ClN6OS2Forma y color:SolidPeso molecular:456.97FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Fórmula:C23H23NO4Pureza:98.85%Forma y color:White SolidPeso molecular:377.433Anti-Human CD88/C5AR1 Antibody (G2_anti-C5aR)
Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.Forma y color:Odour LiquidASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Forma y color:Odour LiquidC1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Fórmula:C16H22Cl3N5Forma y color:SolidPeso molecular:390.738MEDI7814
MEDI7814 is a humanized monoclonal antibody inhibitor targeting C5a and C5adesArg. It has binding affinities of 14 pM for recombinant human C5a and 8 pM for serum-purified human C5a. MEDI7814 shows potential for treating acute inflammatory conditions, including sepsis and renal ischemia-reperfusion injury.C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.Fórmula:C27H35N3O2Pureza:99.76%Forma y color:SolidPeso molecular:433.5857Complement C5-IN-1
CAS:Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).Fórmula:C24H32N2O6Pureza:98.27%Forma y color:White SolidPeso molecular:444.5207Ref: TM-T10863
1mg75,00€5mg145,00€1mL*10mM (DMSO)159,00€10mg195,00€25mg312,00€50mg439,00€100mg628,00€NDT 9513727
CAS:NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.Fórmula:C36H35N3O4Pureza:99.16%Forma y color:SolidPeso molecular:573.68EG00229
CAS:EG00229 blocks VEGF-A/NRP1 binding, IC50 of 3 μM; doesn't affect VEGFR-1/2. It's an NRP1 antagonist.Fórmula:C19H20F3N7O7S3Pureza:98.23%Forma y color:SolidPeso molecular:611.595Ref: TM-T11153
1mg45,00€5mg103,00€1mL*10mM (DMSO)133,00€10mg148,00€25mg238,00€50mg352,00€100mg524,00€200mg749,00€C5aR-IN-1
CAS:C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.Fórmula:C36H39F4N3O2Forma y color:SolidPeso molecular:621.71Factor D inhibitor 6
CAS:Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.Fórmula:C23H22ClFN6O3Forma y color:SolidPeso molecular:484.911Factor B-IN-2
CAS:Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.Fórmula:C25H32N2O4Forma y color:SolidPeso molecular:424.53Vemircopan
CAS:Vemircopan is a complement factor D inhibitor.Fórmula:C29H28BrN7O3Forma y color:SolidPeso molecular:602.482EG01377
CAS:EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.Fórmula:C26H30N6O6S2Pureza:98%Forma y color:SolidPeso molecular:586.68W-54011
CAS:W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).Fórmula:C30H37ClN2O2Pureza:96.8%Forma y color:White SolidPeso molecular:493.08Ref: TM-T17250
1mg79,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg184,00€25mg304,00€50mg491,00€100mg708,00€200mg963,00€
