Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 178 productos para "Sistema complementario".
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C1QA Protein, Human, Recombinant (His & Myc)
C1QA Protein, Human, Recombinant (His & Myc) is expressed in E. coli.Forma y color:Lyophilized PowderPeso molecular:30.7 kDa (predicted)Ref: TM-TMPH-01128
5µg78,00€10µg111,00€20µg178,00€50µg268,00€100µg384,00€200µg592,00€500µg1.054,00€1mg1.648,00€C5AR1 Protein-VLP, Human, Recombinant (His)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.Forma y color:Lyophilized PowderPeso molecular:41.1 kDa (predicted)Ref: TM-TMPH-01022
5µg248,00€10µg414,00€20µg698,00€50µg1.144,00€100µg1.684,00€200µg2.835,00€500µg5.653,00€C1QA Protein, Mouse, Recombinant (His)
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system.Pureza:90% - 92%Forma y color:Lyophilized PowderPeso molecular:25.6 kDa (predicted)Anti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Pureza:95% - 95%Forma y color:Transparent LiquidPeso molecular:150 kDaEmpasiprubart
CAS:Empasiprubart (anti-C2 mAb) inhibits classical & lectin complement pathways upstream of C3, showing efficacy in autoimmune models.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaMBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Pureza:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:31 KDa (reducing condition)Ref: TM-TMPJ-00136
5µg63,00€10µg90,00€20µg138,00€50µg245,00€100µg437,00€200µg782,00€500µg1.710,00€1mg2.457,00€Avacincaptad pegol sodium
CAS:Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Forma y color:SolidPeso molecular:53500Riliprubart
CAS:Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Pureza:95% - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.52 kDaCrovalimab
CAS:Crovalimab (SKY59; RO7112689) is an humanised monoclonal antibody that binds to complement C5 , paroxysmal nocturnal haemoglobinuria (PNH).Pureza:95%Forma y color:Transparent LiquidPeso molecular:~150 kDaRovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Pureza:95% - 95%Forma y color:Transparent LiquidTanruprubart
CAS:Tanruprubart, Humanized anti-C1q mAb, classical complement pathway target, prevents neuroinflammation, for Guillain-Barré syndrome (GBS) studies.Pureza:95% - 95%Forma y color:Transparent LiquidGefurulimab
CAS:Gefurulimab (ALXN-1720) is a bispecific antibody derived from humans, targeting complement C5 and albumin.Forma y color:LiquidComplement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Forma y color:Lyophilized PowderPeso molecular:22 KDa (reducing condition)Ref: TM-TMPJ-00585
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€Anti-Mouse CD11b Antibody (5C6)
Anti-Mouse CD11b Antibody (5C6) inhibits myelomonocytic cell adhesion and inflammatory cell recruitment.Pureza:95%Forma y color:LiquidPeso molecular:150 kDaC5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73FD-IN-1
CAS:FD-IN-1 is an orally active Factor D (FD) inhibitor (IC50=12 nM), inhibits Factor XIa and Tryptase β2 with IC50 values of 7.7 and 6.5 μM, respectively.Fórmula:C23H23NO4Pureza:98.85%Forma y color:White SolidPeso molecular:377.43Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Fórmula:C62H111N11O12Forma y color:SolidPeso molecular:1202.61NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Fórmula:C20H17ClN6OS2Forma y color:SolidPeso molecular:456.97BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Fórmula:C14H10N2O2S2Pureza:98%Forma y color:SolidPeso molecular:302.37C3a Receptor Agonist
CAS:C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.
Fórmula:C27H35N3O2Pureza:99.76%Forma y color:SolidPeso molecular:433.59
