Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 187 productos para "Sistema complementario".
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Tanruprubart
CAS:Tanruprubart, Humanized anti-C1q mAb, classical complement pathway target, prevents neuroinflammation, for Guillain-Barré syndrome (GBS) studies.Pureza:95% - 95%Forma y color:Transparent LiquidAnti-Human/Mouse CD11c Antibody (N418)
Anti-Human/Mouse CD11c Antibody (N418) specifically recognizes mouse CD11c. CD11c forms a heterodimer with CD18 and plays a key role in leukocyte adhesion.Pureza:95%Peso molecular:146.92 kDaAvacincaptad pegol sodium
CAS:Avacincaptad pegol (ARC1905) is an anti-C5 aptamer for AMD study, inhibiting C5 cleavage.Forma y color:SolidPeso molecular:53500Riliprubart
CAS:Riliprubart (SAR445088) is a humanised monoclonal antibody targeting C1s, applicable for neurological disorders such as CIDP, which inhibits activated C1s in the classical complement pathway.Pureza:98.0% (SDS-PAGE); 99.0% (SEC-HPLC) - 98.0% (SDS-PAGE); 99.0% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.52 kDaNGM-621
NGM-621 is a CHO-expressed fully human monoclonal antibody targeting Complement C3, composed of a huIgG1 heavy chain and huκ light chain with a predicted molecular weight of 149.04 kDa. NGM-621 is used as a precise biological reagent for investigating complement-mediated inflammation and immune regulation mechanisms.Pureza:95% - 98.1% (SDS-PAGE); 96.4% (SEC-HPLC)Peso molecular:144.78 kDaAnti-Human CD11a Antibody (MHM24)
Anti-Human CD11a Antibody (MHM24), inhibitory antibody， recognizes both high-affinity and low-affinity conformational forms of the antigen.Pureza:95%Peso molecular:150 kDaAnti-Mouse CD11b Antibody (M1/70)
Anti-Mouse CD11b Antibody (M1/70) inhibits cell adhesion, kills cancer cells and alleviates fibrosis and inflammation.Pureza:95% - 98.1% (SDS-PAGE); 99.8% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:147.31 kDaVensobafusp alfa
CAS:Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Forma y color:LiquidComplement C8 γ Protein, Human, Recombinant (His)
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.Forma y color:Lyophilized PowderPeso molecular:22 KDa (reducing condition)Ref: TM-TMPJ-00585
10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€MBL2 Protein, Human, Recombinant (His)
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.Pureza:> 99.9% - Greater than 95% as determined by reducing SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:31 KDa (reducing condition)Anti-Mouse CD11b Antibody (5C6)
Anti-Mouse CD11b Antibody (5C6) inhibits myelomonocytic cell adhesion and inflammatory cell recruitment.Pureza:95% - 97.7% (SDS-PAGE); 99.4% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.68 kDaErlizumab
CAS:Erlizumab is a humanized anti-CD18 mAb that reduces inflammation and reperfusion injury by blocking leukocyte adhesion.Pureza:95%Peso molecular:98.57 kDaClaseprubart
CAS:Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Pureza:95%Forma y color:LiquidGreziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Forma y color:Odour LiquidC1s-IN-1 trihydrochloride
CAS:C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.Fórmula:C16H22Cl3N5Forma y color:SolidPeso molecular:390.74Anti-Complement Factor B Antibody
Anti-Complement Factor B Antibody is a potent inhibitory antibody targeting complement factor B. Anti-Complement Factor B Antibody demonstrates the capacity to suppress complement-mediated inflammatory responses and provides essential utility for researching alternative pathway-driven immune disorders.C5aR-IN-2
CAS:C5aR-IN-2, a potent C5aR inhibitor, shows promise for researching inflammatory diseases.Fórmula:C36H40FN5O2Forma y color:SolidPeso molecular:593.73Isocyclosporin A
CAS:Isocyclosporin A is a rearranged degradation product. It is formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.Fórmula:C62H111N11O12Forma y color:SolidPeso molecular:1202.61BCX 1470
CAS:BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.Fórmula:C14H10N2O2S2Pureza:98%Forma y color:SolidPeso molecular:302.37NRP1 antagonist 2
CAS:NRP1 antagonist 2 (Compound 1) is an NRP1 antagonist.Fórmula:C20H17ClN6OS2Forma y color:SolidPeso molecular:456.97
