Otros

<p>Chromogenic substrate targeting lipase, C8 esterase</p>

<p>4-Nitrophenyl 5-O-trans-feruloyl-alpha-L-arabinofuranoside is a chromogenic substrate for alpha-L-arabinofuranosidase. Upon hydrolysis, para-nitrophenol is released yielding a yellowish colour. 4-Nitrophenyl 5-O-trans-feruloyl-alpha-L-arabinofuranoside is used in different applications such as the Plant cell wall degradation assays, bacterial enzyme profiling</p>

<p>Crimson-Gal (Crimson-beta-D-galactopyranoside) is a chromogenic indicator for beta-galactosidase activity. The colorless product is cleaved by lactose-utilizing bacteria in liquid media or on agar plates and yields a crimson colored precipitate. Crimson-Gal can also be used as detecting agent for beta-galactosidase activity in reporter gene assays or for identification of positive transformants on agar plates when using the α-complementation approach. Read more in the Application Notes.</p>

<p>Impurity Atenolol EP Impurity H<br>Applications 2-[4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]acetonitrile is an impurity of Atenolol (A790075), a cardioselective β-adrenergic blocker. Atenolol EP Impurity H<br>References Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984);<br></p>

<p>Applications Fulvestrant (F862500) impurity C.<br></p>

<p>Applications Zafirlukast p-Tolyl Isomer is a positional isomer and impurity of the cysteinyl leukotriene type 1 receptor antagonist, Zafirlukast (D226955).<br>References Krishnaiah, C. et al.: Anal. Chem. Ind. J., 8, 471 (2009); Madhavi, A. et al.: Chromatographia, 70, 233 (2009); Goverdhan, G. et al.: J. Pharmac. Biomed. Anal., 49, 895 (2009);<br></p>

<p>Applications Deschloro-Zopiclone is a metabolite of Zopiclone (Z700500) which is a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.<br>References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),<br></p>

<p>Applications Nintedanib Demethyl-O-glucuronic Acid-d3 is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>

<p>Applications Α labelled metabolite of Tamoxifen (T006000).<br>References Sun, D., et al.: Breast Cancer Res., 8(4), (2006), Zheng, Y., et al.: Drug Metab. Dispos., 35, 1942 (2007),<br></p>

<p>Applications 2-((4S,7S,10S,13S,15R)-10-Benzyl-15-hydroxy-7,13-diisobutyl-15-methyl-1-morpholino-2,5,8,11,14,18-hexaoxo-4-phenethyl-17-oxa-3,6,9,12-tetraazanonadecan-19-yl)-2-hydroxysuccinic Acid is an impurity of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>

<p>Applications OR 486 is an anti-inflammatory agent used in the treatment of rheumatoid arthritis and osteoarthritis. Entacapone (E588500) impurity.<br>References Jenei-Lanzl, Z. et al.: Annal Rheum. Dis., 74, 444 (2015); Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),<br></p>

<p>Impurity Atenolol EP Impurity A<br>Applications 4-(Hydroxyphenyl)acetamide (Atenolol EP Impurity A) is used as an intermediate for the synthesis of Atenolol (A790075) and various other organic compounds and pharmaceuticals. It is a process impurity for Atenolol (A790075)<br>References Inkum, R., et al.: Maejo Int. J. Sci. Tech., 6, 372 (2012); Pai, N.R., et al.: J. Chem. Pharma. Rsch., 4, 375 (2012); Moon, J.T., et al.: Bio-org. Medn. Chem., 20, 734 (2012);<br></p>

<p>Applications 1,3-Propanediol is a common organic reagent used in the synthesis of polymers and used in industrial organic chemistry for the synthesis of lubricants, foods, medicines and cosmetics.<br>References Sun, Y. et al.: Bioproc. Renew. Res. Commod. Bioprod., 289 (2014);<br></p>

<p>Applications: Labelled Almotriptan (A575200). Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.<br>References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)<br></p>

<p>Applications Desmethyl Nintedanib Carboxylic Acid is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>

<p>Applications Methyl 4-Hydroxyphenylacetate has been shown to have potent inhibitory activity against tobacco mosaic virus (TMV).<br>References Shen, S., Li, W., Wang, J.: Nat. Prod. Res., 27, 2286 (2013); Golovleva, L.A., et. al.:<br></p>

<p>Applications N-(5-Chloro-2-pyridinyl)-2-pyrazinecarboxamide is an impurity of Zopiclone (Z700500) which is a nonbenzodiazepine hypnotic agent used in the treatment of insomnia.<br>References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990),<br></p>

<p>Applications 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (cas# 1289942-66-0) is a useful research chemical.<br></p>

<p>Applications N-Desmethyl Zopiclone-d8 is a labelled metabolite of Zopiclone (Z700500), which is Cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists. This is a controlled substance (depressant) in the US but not in Canada. Sedative, hypnotic.<br>References Fernandez, C., et al.: Clin. Pharmacokinet., 29, 431 (1995), Nordgren, H., et al.: Ther. Drug Monit., 24, 410 (2002)<br></p>

<p>Applications Oxo-MDV 3100 (Oxo-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011); Ma, X., et al.: J. Pharm. Biomed. Anal., 131, 436 (2016);<br></p>

<p>Applications (2E)-2-Cyano-3-(3-ethoxy-4-hydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.<br>References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),<br></p>

<p>Applications An impurity of Nintedanib, which is an antifibrotic drug.<br>References Holdsworth, G.; et al.: Scientific Reports, 7, 1 (2017)<br></p>

<p>Applications Labelled analogue of cis-Entacapone, the (Z)-Isomer of Entacapone (E558500) polymorphic form B. Antiparkinsonian.<br>References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),<br></p>

<p>Applications Zafirlukast m-Tolyl Isomer is a positional isomer and impurity of the cysteinyl leukotriene type 1 receptor antagonist, Zafirlukast (D226955).<br>References Krishnaiah, C. et al.: Anal. Chem. Ind. J., 8, 471 (2009); Madhavi, A. et al.: Chromatographia, 70, 233 (2009); Goverdhan, G. et al.: J. Pharmac. Biomed. Anal., 49, 895 (2009);<br></p>

<p>Applications A labelled metabolite of the anti-cancer drug Tamoxifen (T006000).<br>References Heiman, D., et al.: J. Med. Chem., 23, 994 (1980), Kier, L., et al.: Pharm. Res., 7, 801 (1990),<br></p>

<p>Stability Hygroscopic<br>Applications (S)-4-Oxo-homophenylalanine Hydrochloride is a derivative of L-Homophenylalanine (H600500); an antitumor agent.<br>References Brunner, Henri., et al.: Eur. J. Med. Chem., 25, 35 (1990)<br></p>

<p>Applications N-Nitroso-1-(2-methoxyphenyl)piperazine is a reagent used in the preparation of 9-aminoacridine-based agents that impair bovine viral diarrhea virus replication.<br>References Loddo, R. et al.: Bio. &amp; Med. Chem., 26(4), 855-868, (2018)<br></p>

<p>Applications Defluoro-MDV 3100 (Defluoro-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011); Ma, X., et al.: J. Pharm. Biomed. Anal., 131, 436 (2016);<br></p>

<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>

<p>Applications Fulvestrant 17-Ketone, is an impurity of Fulvestrant (F862500), a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).<br>References Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-​Amino-​2-​fluoro-​N-​methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors<br>References Ivachtchenko, A. V., et al.: Eur. J. Med. Chem., 99, 51 (2015); Zhang, D., et al.: Bioorg. Med. Chem. Lett., 23, 2408 (2013)<br></p>

<p>Applications It has been used to promote wound healing. Biological stain. Dyes and metabolites, Environmental Testing.<br>References Findlay, J., et al.: J. Pharm. Biomed., Anal., 21, 1249 (2000), Han, D., et al.: J. Agric. Food Chem., 55, 6424 (2007), Jiang, Z;., et al.: J. Environ. Anal. Chem., 88, 649 (2008),<br></p>

<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>

<p>Applications (αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.<br>References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),<br></p>

<p>Stability Hygroscopic<br>Applications A novel active metabolite of the anti-cancer drug Tamoxifen (T006000).<br>References Furr, B., et al.: Pharmacol. Ther., 25, 127 (1984), Leonessa, F., et al.: Cancer Res., 54, 441 (1994), Stearns, V., et al.: Lancet, 360, 1851 (2002), Rae, J., et al.: Pharmacogenetics, 13, 501 (2003), Zheng, Y., et al.: Drug Metab. Dispos., 35, 1942 (2007),<br></p>

<p>Applications Desmethyl 7-Methoxycarbonyl Nintedanib is an impurity of Intedanib (I666650), which is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases. it is an indolinone as triple angiokinase inhibitors and an antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>

<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>

<p>Applications (Z)-4-Hydroxy Tamoxifen O-β-D-Glucuronide is an active metabolite of Tamoxifen (T006000).<br>References Ogura, K. et al.: Biochem. Pharmacol., 71, 1358 (2006); Nishiyama, T. et al.: Biochem. Pharmacol., 63, 1817 (2002); McCague, R. et al.: Biochem. Pharmacol., 39, 1459 (1990);<br></p>

<p>Applications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.<br>References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>

<p>Applications Hydroxyatenolol-d7 is the isotope labelled analog of Hydroxyatenolol (H802480); a metabolite of Atenolol (A790075) which is a cardioselective β-adrenergic blocker, antihypertensive, antianginal, and antiarrhythmic (class II).<br>References Escher, B., et al.: Environ. Sci. Technol., 40, 7402 (2006); Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984)<br></p>

<p>Applications 2,2,4,4-Tetramethyloctane is a volatile compound of vegetarian soybean kapi, a fermented Thai food condiment.<br>References Allagheny, N., et al.: Int. J. Food Microbiol., 29, 321 (1996); Han, B., et al.: Food Control., 15, 265 (2004); Ouoba, L., et al.: J .Appl. Microbiol., 99, 1413 (2005); Zhang, J., et al.: Inter. J. Food Sci. Technol., 42, 263 (2007);<br></p>

<p>Impurity Leuprolide Acetate EP Impurity B TFA salt<br>Applications Synthetic nonapeptide agonist analog of LH-RH. Antineoplastic (hormonal).<br>References Vilchez-Martinez, J.A., et al.: Biochem. Biophys. Res. Commun., 59, 1226 (1974), Sennello, L.T., et al.: J. Pharm. Sci., et al.: 75, 158 (1986), Wheeler, J.M., et al.: Am.J. Obstet. Gynecol., 167, 1367 (1992), Eri, L.M., et al.: J. Urol., 150, 359 (1993),<br></p>

<p>Applications Substrate specificity of haloalkane dehalogenases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),<br></p>

<p>Applications Palbociclib (also known as compound number PD-0332991) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);<br></p>

<p>6-Bromo-2-naphthalenyl-b-D-mannopyranoside is a boronic acid that is used as a universal substrate for the detection of peroxidase activity. This product has been shown to be stable in most culture media and can be used to detect peroxidase activity in food, environmental, and other biological samples. 6-Bromo-2-naphthalenyl-b-D-mannopyranoside also has high purity and is conjugated with various fluorophores for use in chemiluminescence and bioluminescence assays.</p>

<p>Aldol® 470 L-pyroglutamic acid amide is a chromogenic and fluorogenic enzyme substrate used for detection of pyrrolidonyl peptidase (PYRase) activity. The colorless enzyme substrate is cleaved by PYRase-producing bacteria grown in liquid or solid media, yielding orange color. In addition, green fluorescence is generated when a suitable matrix is present, such as, the surface of cellulose acetate filters, polypropylene tubes or microplates, and polyethylene vials. Aldol® 470 L-pyroglutamic acid amide is suitable for use under aerobic and anaerobic conditions.</p>

<p>This compound inhibits the enzyme protein kinase. It has been shown to inhibit the activity of a number of protein kinases including those that are involved in cell proliferation, differentiation and apoptosis. This drug is also known to be a potent inhibitor of human c-Jun N-terminal kinase (JNK) and other types of kinases such as cyclin-dependent protein kinases. The inhibition of these enzymes results in the prevention of tumorigenesis, inflammation and immunological responses.</p>

<p>4-Nitrophenyl 2-O-(b-L-fucopyranosyl)-b-D-galactopyranoside is a high-quality chromogenic substrate with excellent sensitivity specifically designed for enzymes' activity detection. This pNP substrate enables rapid, accurate, and measurable colorimetric visualization of enzymatic hydrolysis reactions. Researchers can easily and effectively monitor the release of 4-nitrophenol as a yellow product under laboratory conditions, allowing for convenient comparative analysis and identification of enzyme levels in various samples.</p>

<p>4-Nitrophenyl b-laminaritrioside is a chemiluminescent substrate that reacts with hydrogen peroxide to produce light. It is used in the detection of bacteria and other microorganisms in culture media, food testing, and diagnostics. 4-Nitrophenyl b-laminaritrioside is also used as a chromogenic or fluorogenic substrate in enzyme assays.</p>

<p>Aldol® 458 phosphate is a chromogenic and fluorogenic enzyme substrate used for detection of phosphatase activity. The colorless enzyme substrate is cleaved by phosphatases secreted by bacteria grown in liquid media, yielding yellow color and green fluorescence. Aldol® 458 phosphate can also be used in assays involving phosphatase-coupled antibodies in immunoassay applications (ELISA). Aldol® 458 phosphate can be used under aerobic and anaerobic conditions.</p>

<p>3-Indolyl b-D-cellotetraoside is a chemiluminescent substrate that is used as an indicator in the detection of aminoglycosides. The ligand is a cell wall component that has been shown to bind specifically to the active site of bacterial β-lactamases, which are enzymes that catalyze the hydrolysis of β-lactam antibiotics. 3-Indolyl b-D-cellotetraoside can be used for bacterial identification and enumeration, food testing, and enzyme substrate for diagnostics. It fluoresces in response to electron excitation with a wavelength of about 590 nm.</p>

<p>3-Indolyl-b-D-cellobioside is a fluorogenic substrate for alkaline phosphatase. It can be used in food testing, environmental testing, and diagnostics. 3-Indolyl-b-D-cellobioside is a chromogenic substrate for beta-galactosidase. It can be used in staining and enzyme substrates. 3-Indolyl-b-D-cellobioside is also a ligand for alkaline phosphatase. It can be used in conjugates and chemiluminescence or bioluminescence reactions. 3-Indolyl -b -D -cellobioside is a high purity product with high quality standards that are suitable for use in culture media.br&gt;br&gt;<br>3 - Indolyl - b - D - cellobioside <br>CAS No . 914912 - 14 - 4 <br>Food testing <br>St</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-4,6-O-benzylidene-b-D-glucopyranoside is a fluorescent substrate for beta amylase and other glycosidases. It has been used as a fluorogenic substrate for food testing and as a chromogenic substrate for environmental testing. 4NPB has also been used in diagnostic applications such as enzyme substrates, ligands, and chemiluminescent substrates. This product is of high purity and quality with a conjugate that can be used in biotechnology applications.</p>

<p>Neu5Ac(a2-6)Gal(b1-3)GlcNAc-b-pNP is a fluorogenic substrate that can be used for testing the presence of glycoproteins in food samples. It also has been used to detect the presence of enzymes in culture media. Neu5Ac(a2-6)Gal(b1-3)GlcNAc-b-pNP is a high purity product that has a CAS number and is available as a conjugate. This product can be purchased in bulk quantities, with a purity of &gt;90%.</p>

<p>N-Benzoyl-Val-Gly-Arg p-nitroanilide hydrochloride is a fluorogenic substrate that can be used for the detection of β-glucuronidase. It has been shown to have high purity and quality, which makes it an excellent choice for use in food testing and staining.</p>

<p>[2-Methoxy-4-(2-nitrovinyl)phenyl] b-D-galactopyranoside (MNVP-gal) is a chromogenic enzyme substrate that is commonly used to detect the activity of beta-galactosidase in biological samples. MNVP-gal produces a distinctive magenta color when hydrolyzed by beta-galactosidase, making it particularly useful for applications where visual detection is necessary. This substrate is also resistant to endogenous proteases, making it well-suited for use in cellular and tissue preparations.</p>

<p>Aldol® 455 is a substrate for the enzyme beta-galactosidase. It is used in food testing, staining, and environmental testing. Aldol® 455 has been shown to be a good substrate for fluorogenic and chromogenic substrates. It can be conjugated with an antibody or other ligand for use in immunoassays. Aldol® 455 is of high purity and high quality, making it suitable for use in diagnostics and as an enzyme substrate. This product can also be used as a culture media additive.</p>

<p>4-Nitrophenyl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside enzyme substrate is a versatile and reliable reagent for measuring glucosidase activity. It is an ideal substrate for use in assays to detect β-glucosidase activity in a variety of applications, including for in vitro and in vivo studies, and it has been widely used in the pharmaceutical and biotechnology industries. This chromogenic pNP enzyme substrate is designed for effective and precise analysis with good sensitivity and low background signals.</p>

<p>2-Nitrophenyl-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a tri-O-acetylated glucuronide substrate commonly used in chromogenic assays to detect the activity of beta-glucuronidase. Upon hydrolysis by the enzyme, the substrate releases 2-nitrophenol, which can be spectrophotometrically. The substrate is widely used in diagnostic tests to assess bacterial and fungal infections, as well as in drug metabolism studies.</p>

<p>4-Nitrophenyl 2,4,6-tri-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside is an advanced bifunctional chromogenic pNP substrate specifically tailored for the simultaneous detection and quantification of multiple glycosidase enzymes. This dual-action substrate undergoes cleavage by two separate enzymatic reactions, which increases the range and sensitivity of detection. The resulting 4-Nitrophenol release can be easily measured spectrophotometrically, providing rapid and reliable enzyme analysis for advanced enzymology studies, enabling new discoveries in biochemistry and biotechnology.</p>

<p>Aldol 496 acetate is a chromogenic substrate for the enzyme Aldolase. It is also used as a ligand to detect the presence of Aldolase in biological fluids and tissues. This product is designed for Food testing, Diagnostics, Chromogenic substrate, Staining, Enzyme substrate, Bioluminescence, Fluorogenic substrate, Chemiluminescence, and Culture media. Aldol 496 acetate is an organic chemical with high purity and high quality.</p>

<p>2-Bromo-4-nitrophenyl b-D-galactopyranoside is a chemiluminescent substrate that is used for the detection of β-galactosidase activity in the biochemical reaction. It has been shown to be an excellent ligand for metal ions and can be used as a reagent in the determination of metal ions in biological systems. This product is manufactured with high purity and quality, which ensures its suitability for use in culture media, environmental testing, and diagnostics. 2-Bromo-4-nitrophenyl b-D-galactopyranoside has been tested as a fluorogenic substrate for β-galactosidase. It has also been used as a chromogenic substrate for β-galactosidase and an enzyme substrate for β-galactosidase. This product can be conjugated with other molecules such as biotin to enable rapid analysis of proteins or</p>

<p>2-Nitrophenyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside is a fluorescent substrate for β-galactosidase. It is used in food testing, environmental testing and diagnostics. This substrate is also used to detect the presence of β-galactosidase activity in cells and tissues.<br>2NPTABG provides a fluorescence signal that can be detected with an ultraviolet light or a luminometer. The luminescence intensity decreases when it reacts with β-galactosidase enzyme.<br>This product has a CAS number of 3053-17-6 and is available at high purity levels.</p>