Antraquinonas y derivados

<p>Daunorubicin metabolite</p>

<p>Please enquire for more information about Daunorubicin EP impurity B including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Annamycin, a semi-synthetic doxorubicin derivative, binds DNA, blocks topoisomerase II, and evades MDR, inhibiting DNA/RNA/protein synthesis.</p>

<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>

<p>Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>