Carbohidratos y glucoconjugados

<p>3'-Sulfated Lewis X methyl glycoside is a synthetic, fluorinated oligosaccharide that can be used as a sugar or as an intermediate in the synthesis of complex carbohydrates. It is available for custom synthesis and modification to meet your specific needs. 3'-Sulfated Lewis X methyl glycoside is a monosaccharide that has been modified with a click reaction to attach sulfate groups. This modification allows for easier saccharide recognition and binding in the body. The CAS number for 3'-sulfated Lewis X methyl glycoside is 386264-50-2.</p>

<p>The core trisaccharide of the ganglioside GD2,protected with a propargyl glycoside group, is the most prominent alkynyl glycoside used in oligosaccharide synthesis (Das, 2016). The structure (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Sialyl-Lex-hexa-APD-HSA is a high purity synthetic glycosylation that is custom synthesized. It has been modified with fluorination, methylation, and click modification. Sialyl-Lex-hexa-APD-HSA can be used in the synthesis of complex carbohydrates and is available in CAS Number: 75869-57-3.</p>

<p>Ganglioside GM3NeuGc (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with N-glycolyl sialic acid linked α2,3 to the galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM3(NeuGc) ganglioside is of interest due to its restrictive expression in normal human tissues, according to immunohistochemical studies, using either polyclonal or monoclonal antibodies. However, both immunohistochemical and biochemical methods have strongly suggested its over-expression in human breast tumours (Oliva, 2006). It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019).</p>

<p>Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-O-benzylb -D-galactopyranoside is a Fluorination and Glycosylation product. It is a Custom Synthesis of Monosaccharide and Oligosaccharide. The CAS number for this product is 106835-99-8.</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>NGA3F N-Glycan is a custom synthesis product that has been fluorinated, methylated, and modified with a click modification. It is a monosaccharide that can be found in the form of polysaccharides or glycosylations. This product is made of saccharides, which are carbohydrates that have been modified with glycosylation or polysaccharide modifications. NGA3F N-Glycan can be used in a variety of applications such as pharmaceuticals, food additives, and cosmetics.</p>

<p>Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP is a modified oligosaccharide with a carbohydrate backbone of 3 mannose and 1 galactose residues. The saccharide is synthesized from the monosaccharides methylated, glycosylated, and then fluorinated. Gal[2346Ac]b(1-3)GalN3[46Bzd]-b-MP has a CAS number of 71769-77-5.</p>

<p>CAS No. 71208-05-4 is a complex carbohydrate that belongs to the group of oligosaccharides, polysaccharides and modifications of saccharides. This compound was synthesized by methylation, glycosylation, carbamoylation and fluorination. It is available in high purity and with low impurities.</p>

<p>Gala1-3Galb1-3GlcNac</p>

<p>3'-Sialyllactose-APD-HSA is a complex carbohydrate with Oligosaccharide and Polysaccharide. It is a modification of saccharides, which are composed of monosaccharides or simple sugars. 3'-Sialyllactose-APD-HSA is a synthetic compound that has been modified by the addition of fluorine atoms to the sugar molecule. This modification prevents the sugar from being broken down by enzymes in the body and ensures that it remains intact until it reaches its target site. 3'-Sialyllactose-APD-HSA is used as a drug delivery system for cancer drugs, such as doxorubicin and paclitaxel.</p>

<p>Hyaluronate fluorescein is a polymer of hyaluronic acid that has been modified with fluorescein. It is synthesized by the methylation and saccharide coupling of an oligosaccharide, followed by Click modification and the addition of a fluorescent dye. Hyaluronate fluorescein has a molecular weight of 2500kDa. It is highly purified and can be custom-synthesized to suit specific needs.</p>

<p>Methylation, Custom synthesis, Click modification, CAS No., Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity, Modification. Monosaccharide sugar. Synthetic.<br>2-Anhydro-4-O-(a-L-idopyranosyluronic acid 2-sulfate)-D-mannofuranose 6-sulfate trisodium salt is a methylated and modified form of D-mannose. It is a monosaccharide with a molecular weight of 376.34 and a CAS number of 64459-77-5. This product can be used in the synthesis of oligosaccharides or polysaccharides as well as in the production of high purity mannose derivatives with modified linkages.</p>

<p>NA3 N-glycan is a base that forms glycosidic bonds with other molecules. It has been shown to be pharmacologically active in tissues and has a safety profile. NA3 N-glycan is metabolized by the serine protease, which cleaves it from its glycosylated protein. The resulting molecule lacks a reactive group, which prevents it from forming toxic reactions with other molecules. NA3 N-glycan has been used for pharmacokinetic modeling and for mass spectrometric measurements of proteins in human serum and plasma.</p>

<p>Hyaluronate biotin (HB) is a modified form of hyaluronic acid. It is produced by the methylation and glycosylation of hyaluronic acid and it has an average molecular weight of 250 kDa. HB is used in tissue engineering, cell culture, and as a contrast agent for magnetic resonance imaging. The modification of hyaluronate with biotin allows for the visualization of HB using immunofluorescence microscopy. Hyaluronate biotin is a synthetic product that can be custom-synthesized to customer specifications, such as purity level, oligosaccharide content, and monosaccharide content.</p>

<p>Difucosyl-para-lacto-N-hexaose I is a synthetic oligosaccharide that is used as a model for the longum subsp. of human milk oligosaccharides. The Difucosyl-para-lacto-N-hexaose I oligosaccharide was synthesized from sucrose and alpha-(1,2)-fucopyranosyl chloride, which were then reacted with para-nitrophenyl bromide (PNP). This product has been shown to inhibit the growth of respiratory pathogens in vitro by binding to c-reactive protein. It also binds to the Fc region of immunoglobulins and can act as an adjuvant for vaccines.</p>

<p>Decasaccharide dp10 is a complex carbohydrate that is made up of ten monosaccharides. It is a synthetic oligosaccharide that has been fluorinated and glycosylated. The decasaccharide has been synthesized using click chemistry and methylation, before being purified to produce a high-purity product. Decasaccharide dp10 can be used in the modification of complex carbohydrates, as well as for the synthesis of glycans with customized structures.</p>

<p>Octyl 2-acetamido-2-deoxy-b-D-glucopyranosyl-(1-2)-a-D-mannopyranosyl-(1-2)-b-D-glucopyranoside is a custom synthetic sugar that is used in the synthesis of complex carbohydrates. This product has been fluorinated to give it a high level of purity and is available for purchase at CAS No. 1268248-67-4. Octyl 2 acetamido 2 deoxy b D glucopyranosyl (1 2) a D mannopyranosyl (1 2) b D glucopyranoside has been modified with methylation, Click modification, and glycosylation. It can be used in polysaccharide synthesis or glycosylation reactions to produce polysaccharides with different properties.</p>

<p>α-1,4-glucododecasaccharide derived from starch by hydrolysis and chromatography</p>

<p>NA2B N-Glycan is a custom synthesis of a polysaccharide, glycosylation sugar that contains an oligosaccharide chain. The NA2B N-Glycan is modified with fluorination, methylation, and click modification. It has no CAS number, but it is available for purchase from various suppliers. The NA2B N-Glycan is synthesized by the glycosylation of a saccharide and can be used as a complex carbohydrate.</p>

<p>2,3,1',3',4',6'-Hexa-O-acetyl-sucrose is a custom synthesis carbohydrate with a complex structure. The chemical name for this compound is 2,3,1',3',4',6'-hexahydroxy-α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside. It has the CAS number 52706-47-5 and the molecular weight of 593.54 g/mol. This product can be used in various applications including Oligosaccharides, Polysaccharides, Modification, saccharide, Methylation, Glycosylation, Click modification and Carbohydrate. 2,3,1',3',4',6'-Hexa-O-acetyl-sucrose is also a high purity product that is Fluorinated and Synthetic.</p>

<p>1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] is a complex carbohydrate that contains a fluorinated sugar. It is synthesized from a monosaccharide and an oligosaccharide and glycosylated with a polysaccharide. The compound has been modified to include methylation and click modification. 1-D-a-Galactopyranosyl-4-O-[1-(2-octadecylthioethyl)-(b-D-galactopyranoside)] can be purchased in high purity from the CAS registry number of 538570–75–6.</p>

<p>8-Methoxycarbonyl-3-benzyl-3',4',6',6-tetra-O-acetyl-N,N'-diacetyl b-chitobioside is a synthetic product that belongs to the class of glycosides. This compound has been modified by the incorporation of methyl and fluorine atoms. It is used as an intermediate in the synthesis of oligosaccharides and saccharides for use in biotechnology research.</p>

<p>Glycyl-3'-fucosyllactose is a synthetic, fluorinated polysaccharide that can be modified with glycosylation and methylation. It has the CAS No. of 12078-02-9 and is a high purity product.</p>

<p>Man-7D1 N-glycan is a synthetic, fluorinated, monosaccharide oligosaccharide that is custom synthesized for glycosylation. It has been shown to be an effective substrate for glycosylation and can be used in the synthesis of complex carbohydrates. The modification of Man-7D1 N-glycan includes fluorination, methylation, and click chemistry. This product is available in high purity and with a CAS number 83178-05-6.</p>

<p>Man-8 N-glycan is a modification of the carbohydrate Man-8. It is a complex carbohydrate that is synthesized from monosaccharides and polysaccharides. This product has been custom synthesized for high purity and high quality. It has been fluorinated to increase its stability, and it can be used in glycosylation reactions.</p>

<p>Methyl 4-O-(a-D-galactopyranosyl)-b-D-galactopyranoside is a modification of a sugar molecule. It is an oligosaccharide that is a complex carbohydrate. This product can be custom synthesized to order with high purity and CAS number. The chemical name for this product is methyl 4-O-(a-D-galactopyranosyl)-b-D-galactopyranoside, which is a monosaccharide. Methyl 4-O-(a-D-galactopyranosyl)-b-D-galactopyranoside has glycosylation and polysaccharides. This product can be fluorinated or saccharified with methylation.</p>

<p>Gala1-2Gal-BSA is a modified oligosaccharide with the chemical formula of C(3)H(6)O(4)n. It is a carbohydrate that can be synthesized from galactose and alpha-galactosyltransferase. Gala1-2Gal-BSA has been shown to have anti-cancer properties in vitro, but its mechanism of action is not known.</p>

<p>Lacto-N-fucopentaose III-APD-HSA is a custom synthesis, complex carbohydrate that has been modified with methylation and glycosylation. It is an oligosaccharide that is found in human serum albumin. Lacto-N-fucopentaose III-APD-HSA has been shown to have antitumor activity. It also inhibits the growth of bacteria by binding to bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. This compound binds to two sites on the 16S ribosomal RNA of bacteria and can inhibit protein synthesis, leading to cell death by inhibiting production of proteins vital for cell division. Lacto-N-fucopentaose III-APD-HSA has undergone fluorination and click modification.<br>Methylation: A process whereby a methyl group (-CH3) is added to an organic molecule via a chemical</p>

<p>a1,6-Mannobiose-BSA is a fluorinated monosaccharide that has been synthesized from mannose. It is a synthetic oligosaccharide that is used in glycosylation and polysaccharide modification. The compound has been modified with methyl groups and has undergone click chemistry to produce a reactive site on the sugar ring. This product has been synthesized using high purity reagents and has CAS No. 73978-99-2.</p>

<p>Ganglioside GM3 (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked a2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain and melanomas where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganlioside is implicated in various other diseases involving chronic inflammation, such as, insulin resistance, leptin resistance, T-cell function and immune disorders (e.g. allergic asthma). GM3 ganglioside has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>a-Heptasaccharide is a complex carbohydrate that is synthesized from glycerol and seven monosaccharides. It is used in the synthesis of other carbohydrates and as a fluorination reagent.</p>

<p>Man-9-Glc N-Glycan is a synthetic carbohydrate that is a modification of the natural sugar, Man-9-GlcNAc. It can be used as an ingredient in pharmaceutical products, such as vaccines and other therapeutic agents. This product is a custom synthesis that can be produced to order.</p>

<p>Lacto-N-fucopentaose II-APD-KLH is a fluorinated, monosaccharide, synthetic, oligosaccharide, complex carbohydrate. It has CAS No. 21973-23-9 and a custom synthesis. Lacto-N-fucopentaose II-APD-KLH can be used as a glycosylation or polysaccharide with click modification or methylation. The high purity of this product is 99%.</p>

<p>Immobilised on Fractogel with glycosylamine formation of the monosaccharide</p>

<p>Man5GlcNAc is a glycoprotein that is expressed in the Golgi apparatus of mammalian cells. It is cleaved by alpha-mannosidase II and alpha-mannosidase I, which are enzymes located in the golgi apparatus. Man5GlcNAc has been shown to be an effective glp-1 analogue, which is a hormone that stimulates insulin secretion. This protein has also been shown to have structural similarities to high mannose type oligosaccharides, which are found on the surface of some bacteria. The protein may also act as a signal peptide for proteins that are exported from the golgi to the cell membrane.</p>

<p>GQ1b ganglioside (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Anti-GQ1b ganglioside antibody is associated with Miller Fisher syndrome and is also found in patients with related conditions that may share the same pathogenic mechanism, such as, Bickerstaff brainstem encephalitis. Thus, the measurement of anti-GQ1b antibody in suspected cases of Miller Fisher syndrome is a useful diagnostic marker (Paparounas, 2004). It has been found that GQ1b ganglioside contributes to synaptic transmissions and synapse formation. Low concentrations of GQ1b ganglioside, evoked dopamine (DA) release from laboratory tissues (Chen, 2018).</p>

<p>1,6:2,3-Dianhydro-4-O-(methyl 2,3-di-O-benzyl-b-D-glucopyranosyluronate)-b-D-mannopyranose is a sugar that can be synthetically produced from methylated saccharides. The compound is a complex carbohydrate with a number of functional groups including hydroxyl and methyl groups. The compound is also known as Methyl 2,3:di:O:benzyl b(1→4)-D-glucopyranoside (2→3) -4→6)-b(1→4) -mannopyranose. This product has CAS No. 87907-24-2 and can be custom synthesized to order on request.</p>

<p>Man-3b N-Glycan is a glycan with a mannose backbone and an N-acetylglucosamine branch. This glycan can be customized to the user’s specification, including the desired sugar sequence and the length of the oligosaccharide. Man-3b N-Glycans are synthesized by modification of commercially available saccharides or by custom synthesis.</p>

<p>Maltotetraose-APD-HSA is a complex carbohydrate with a high purity. Maltotetraose-APD-HSA is a synthetic oligosaccharide that has been modified by glycosylation, methylation, and fluorination. It is an alpha 1,4 linked maltotetraose that has been conjugated to HSA. Maltotetraose-APD-HSA has the CAS number 113789-04-8 and its molecular weight is 495.7 Da. Maltotetraose-APD-HSA can be found in the monosaccharides saccharide and carbohydrate categories.</p>

<p>1,2,3,4-Tetra-O-acetyl-6-O-(2,3,4,6-tetra-O-acetyl-aD-mannopyranosyl)-D-mannopyrannose is a tetrasaccharide that can be synthesized by modifying the sugar moiety of 1,2,3,4-tetra-O-[(2,3,4)-triacetyl]-6-[(1R)-1-(2,3,4,-triacetyl)glycoloyl]aD mannopyranose. This modified sugar moiety is then reacted with methyl fluoride to produce 1. It has been shown to inhibit the growth of bacteria and fungi.</p>

<p>3'-Sialyllactose-GEL is a custom synthesis of a complex carbohydrate. It has CAS No. and is a polysaccharide that has been modified by methylation, glycosylation, and click modification. 3'-Sialyllactose-GEL is a high purity product with fluorination. It is synthetic and has a molecular weight of 1,000 Daltons.</p>

<p>N-Glycolyl GM1 ganglioside has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with N-glycolyl sialic acid linked α2,3 to the central galactose residu,e and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). SV40, Py, and the human BK viruses are unusual among viruses in that they use glycolipids as their major cell surface receptors. SV40 uses the N-glycolylneuraminic acid (NeuGc) analog of the ganglioside GM1 [GM1(Gc)] as the cell surface receptor and it gave markedly stronger binding signals than the NeuAc analog [GM1(Ac)] (Campanero-Rhodes, 2007).</p>

<p>Maltotriose hydrate is a synthetic glycosylation product that is synthesized by the fluorination of maltotriose. Maltotriose hydrate is a sugar with a 3-D structure that is similar to maltodextrin, but with one less glucose residue. Maltotriose hydrate can be used in the synthesis of oligosaccharides and polysaccharides and has been shown to have high purity. Maltotriose hydrate can be modified by a variety of reactions, such as methylation, monosaccharide modification, or click chemistry. It has an CAS number and can be custom synthesized for clients' needs.</p>

<p>2, 3, 6, 2', 3', 4', 6'-Hepta-O-acetyl-D-maltose is a fluorinated monosaccharide that is used in the synthesis of glycosides. It has a CAS number of 56285-96-2 and can be custom synthesized. This product is an oligosaccharide that can be modified by glycosylation, methylation, or click modification. It is a complex carbohydrate with a high purity and can be used in the modification of sugars.</p>

<p>Man-2a N-glycan is a modification of the oligosaccharide mannose that is an important component of many glycoproteins. This product can be custom synthesized, and has been shown to have high purity. It is a carbohydrate that contains a monosaccharide and a polysaccharide. The glycan may also contain methylation, glycosylation, or fluorination. It has CAS No. 491845-49-9, which is the number assigned by the Chemical Abstracts Service (CAS) division of the American Chemical Society to identify substances.</p>

<p>α-6⁴-6³-Di-galactosyl-mannopentaose is a specialized oligosaccharide, which is a type of complex carbohydrate. This compound is derived from natural plant sources and its structure comprises a mannopentaose core linked with two galactose units. The mode of action involves specific interactions with gut microbiota, where it selectively enriches beneficial bacterial populations, such as Bifidobacteria and Lactobacilli. These interactions occur by serving as a fermentation substrate, promoting the growth of microbes that confer beneficial effects on host health.</p>

<p>Methyl 6-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a white crystalline solid that belongs to the category of carbohydrates. It is a synthetic carbohydrate with a molecular weight of 496.06 and a CAS number of 3489-94-3. This product has been custom synthesized for research purposes, and can be purchased in high purity (&gt;98%) from various suppliers. It is an oligosaccharide that contains a single sugar unit, which is galactose. This product has been modified with fluorination and methylation to prevent hydrolysis by esterases and glucuronidases, respectively. It also has glycosylation sites on the terminal glucose residues that allow for further modification with other carbohydrates or proteins. The methyl 6-O-(b-D-galactopyranosyl)-b-D-galactopyranoside can be used as an affinity ligand</p>

<p>4-O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-1,6-di-O-benzyl-2-deoxy--aDmuramic acid methyl ester is a synthetic carbohydrate. It is a modification of an oligosaccharide and can be used as a starting material in the synthesis of complex carbohydrates. 4ODBGMEM is synthesized by acetylation of 1,6 di O benzyl 2 deoxy a D muramic acid methyl ester with acetic anhydride and triethylamine. The compound has been shown to be effective in fluoroquinolone resistance and methicillin resistance.</p>