Cetonas y Derivados
Las cetonas son compuestos orgánicos que contienen un grupo carbonilo (C=O) unido a dos átomos de carbono, formando una estructura en la que el grupo carbonilo está flanqueado por grupos alquilo o arilo. En farmacología, las cetonas se utilizan en la formulación de APIs debido a su capacidad para mejorar la solubilidad y estabilidad de los principios activos. Algunas cetonas tienen propiedades antiinflamatorias, analgésicas y antimicrobianas. Los derivados de cetonas incluyen compuestos en los que el grupo carbonilo está modificado, como los enoles, que tienen aplicaciones en la síntesis de fármacos y como intermediarios químicos en la fabricación de otros compuestos bioactivos. Los derivados de cetonas se utilizan en el diseño de nuevos medicamentos, incluidos aquellos para tratar enfermedades neurodegenerativas, trastornos metabólicos y ciertos tipos de cáncer, gracias a sus efectos específicos sobre enzimas y procesos celulares.
Se han encontrado 2393 productos de "Cetonas y Derivados"
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Nitrobenzene
CAS:Producto controlado<p>Applications Nitrobenzene is a compound that exhibits chromosomal genotoxicity against hamster lung cells, and has the potential to cause cancer in humans (1,2). Nitrobenzene is also used as a starting material to synthesize 4-Aminophenol (A618920) through catalytic hydrogenation (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Bonacker, D. et al.: Arch. Toxicol. 2004 Jan;78(1):49-57.2. Hsu, C. et al.: J. Environ. Sci. Health. C. Environ. Carcinog. Ecotoxicol. Rev. 2007 Apr-Jun;25(2):155-843. Rode, C. et al.: Org. Proc. Res. Dev. 1999 Nov;3(6), pp 465–470<br></p>Fórmula:C6H5NO2Forma y color:Light YellowPeso molecular:123.113-(1-Cyanoethyl)benzoic Acid
CAS:Producto controlado<p>Applications 3-(1-Cyanoethyl)benzoic Acid is an intermediate for the synthetic preparation of various pharmaceutical compounds. 3-(1-Cyanoethyl)benzoic Acid was used in studies examining the enantioselectivity of nitrile hydratases.<br>References Rzeznicka, K., et al.: App. Microbiol. Biotechnol., 85, 1417 (2010); Van Pelt. S., et al.: Org. Biomole. Chem., 9, 3011 (2011);<br></p>Fórmula:C10H9NO2Forma y color:BeigePeso molecular:175.183,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Fórmula:C10H12O5Forma y color:White To BeigePeso molecular:212.20rac 1-Methoxy Ketorolac
CAS:Producto controlado<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Fórmula:C16H15NO4Forma y color:NeatPeso molecular:285.29Desmethyl Ketoprofen
CAS:Producto controlado<p>Impurity Ketoprofen EP Impurity B<br>Applications Desmethyl Ketoprofen (Ketoprofen EP Impurity B) shows antiinflammatory and analgesic activities. It can be used as neoplasm inhibitors and for treatment of angiogenesis-related disorders.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Fórmula:C15H12O3Forma y color:WhitePeso molecular:240.25Ketoprofen Ethyl Ester
CAS:Producto controlado<p>Applications Ketoprofen ethyl ester is an impurity of Ketoprofen (K200800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Borodkin, S., et al.: J. Pharm. Sci., 59, 481 (1970), Shanbag, V., et al.: J. Pharm. Sci., 81, 149 (1991), Khan, M., et al.: Eur. J. Med. Chem., 40, 371 (2005),<br></p>Fórmula:C18H18O3Forma y color:ColourlessPeso molecular:282.334-Acetylamino-2-chlorophenol
CAS:Producto controlado<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C8H8ClNO2Forma y color:White To Light PurplePeso molecular:185.61(R)-Apomorphine-10-sulfate
CAS:Producto controladoFórmula:C17H17NO5SForma y color:NeatPeso molecular:347.39N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Producto controlado<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C16H16N2O4Forma y color:NeatPeso molecular:300.313-Hydroxy Medetomidine
CAS:Producto controlado<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Fórmula:C13H16N2OForma y color:NeatPeso molecular:216.28Terpinolene (~90%)
CAS:Producto controlado<p>Applications Terpinolene is a chemical constituent of essential oils found in many plant species and exhibits analgesic and anti-inflammatory properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Macedo, E. M., et al.: Braz J Med Biol Res. 49, S0100 (2016); Garcia, G., et al.: Molecules. 22, E921 (2017)<br></p>Fórmula:C10H16Pureza:>85%Forma y color:ColourlessPeso molecular:136.233-Acetylbenzophenone
CAS:<p>Impurity Ketoprofen EP Impurity A; Ketoprofen USP Related Compound D<br>Applications 3-Acetylbenzophenone (Ketoprofen EP Impurity A) is a Ketoprofen intermediate. Ketoprofen USP Related Compound D.<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Zhang, X., et al.: Bioorg. Med. Chem. Lett., 14, 1205 (2004),<br></p>Fórmula:C15H12O2Forma y color:Off-White To Light YellowPeso molecular:224.25Nordihydrocapsaicin
CAS:Producto controlado<p>Applications Nordihydrocapsaicin is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>Fórmula:C17H27NO3Forma y color:Off-WhitePeso molecular:293.402-Butyl-6-methoxynaphthalene
CAS:Producto controlado<p>Applications 2-Butyl-6-methoxynaphthalene is an impurity of Nabumetone (N200500), an anti-inflammatory and antibacterial agent.<br>References Najera, C., et al.: Adv. Syn. Cat., 346, 1798 (2004); Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Fórmula:C15H18OForma y color:White To GreyPeso molecular:214.32′,4′,5′-Trifluoropropiophenone
CAS:Fórmula:C9H7F3OForma y color:Low Melting SolidPeso molecular:188.1496-Methoxy-2-naphthaleneacetic Acid-d3 (Desmethyl Naproxen-d3)
CAS:Producto controlado<p>Applications A labelled metabolite of Nabumetone (N200500). A competitive, non-selective COX inhibitor.<br>References Turpeinen et. al.: Drug Metabolism and Dispositoin, 37: 1017 (2009); Daniels, F., et al.: J. Invest. Dermatol., 44, 259 (1965), Bosca, F., et al.: Photochem. Photobiol., 71, 173 (2000),<br></p>Fórmula:C13H9D3O3Forma y color:White To Off-WhitePeso molecular:219.254'-Isobutylacetophenone
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Fórmula:C12H16OForma y color:Colourless To Light YellowPeso molecular:176.253-Methylbenzophenone
CAS:<p>Applications 3-Methylbenzophenone (cas# 643-65-2) is a useful research chemical.<br></p>Fórmula:C14H12OForma y color:NeatPeso molecular:196.24
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