Cetonas y Derivados
Las cetonas son compuestos orgánicos que contienen un grupo carbonilo (C=O) unido a dos átomos de carbono, formando una estructura en la que el grupo carbonilo está flanqueado por grupos alquilo o arilo. En farmacología, las cetonas se utilizan en la formulación de APIs debido a su capacidad para mejorar la solubilidad y estabilidad de los principios activos. Algunas cetonas tienen propiedades antiinflamatorias, analgésicas y antimicrobianas. Los derivados de cetonas incluyen compuestos en los que el grupo carbonilo está modificado, como los enoles, que tienen aplicaciones en la síntesis de fármacos y como intermediarios químicos en la fabricación de otros compuestos bioactivos. Los derivados de cetonas se utilizan en el diseño de nuevos medicamentos, incluidos aquellos para tratar enfermedades neurodegenerativas, trastornos metabólicos y ciertos tipos de cáncer, gracias a sus efectos específicos sobre enzimas y procesos celulares.
Se han encontrado 2393 productos de "Cetonas y Derivados"
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4'-Methylacetophenone
CAS:Producto controlado<p>Impurity Celecoxib Impurity<br>Applications 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.<br>References Dwivedi, U.N. et al.: Acta Polym., 39, 596 (1988); Opdyke, D.L.J. et al.: Food Cosm. Toxicol., 12, 933 (1974);<br></p>Fórmula:C9H10OForma y color:NeatPeso molecular:134.18rac Ketorolac Acyl-β-D-glucuronide (Mixture of Diastereomers)
CAS:Producto controlado<p>Stability Moisture Sensitive, Light Sensitive<br>Applications A metabolite of Ketorolac.<br>References Mroszczak, E., et al.: Drug Metab. Dispos., 15, 618 (1987), Brocks, D., et al.: Clin. Pharmacokinet., 23, 415 (1992), Vakily, M., et al.: Pharm. Res., 12, 1652 (1995), Gillis, J., et al.: Drugs, 53, 139 (1997),<br></p>Fórmula:C21H21NO9Forma y color:NeatPeso molecular:431.39Phenacetin
CAS:Producto controlado<p>Applications Analgesic, antipyretic. Component of APC tablets, analgesic mixture also containing aspirin and caffeine. Phenacetin is reasonably anticipated to be a human carcinogen; analgesic mixtures containing Phenacetin are listed as known human carcinogens.<br>References Boyd, et al.: Toxicol. Appl. Pharmacol., 1, 240 (1959), Dubach, C.U., et al.: N. Engl. J. Med., 308, 357 (1983),<br></p>Fórmula:C10H13NO2Forma y color:WhitePeso molecular:179.22rac-Ketoprofen Tris Base Amide
CAS:Producto controlado<p>Applications rac-Ketoprofen Tris Base Amide is derived from rac Ketoprofen (K200800), which is an anti-inflammatory and analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990);<br></p>Fórmula:C20H23NO5Forma y color:NeatPeso molecular:357.15762285Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Fórmula:C20H22N2O2Forma y color:White To Light BeigePeso molecular:322.405-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Producto controladoFórmula:C13H14N2Forma y color:NeatPeso molecular:198.26Acetaminophen (1 mg/mL in Methanol)
CAS:Producto controladoFórmula:C8H9NO2Forma y color:Single SolutionPeso molecular:151.16Nabumetone
CAS:Producto controlado<p>Applications Nabumetone is an anti-inflammatory and antibacterial agent (1). A non-steroidal anti-inflammatory prodrug used for treatment of inflammatory and degenerative rheumatic diseases.<br>References (1) Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)<br></p>Fórmula:C15H16O2Forma y color:NeatPeso molecular:228.29Niflumic Acid
CAS:Producto controlado<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>Fórmula:C13H9F3N2O2Forma y color:Light YellowPeso molecular:282.22p-Ethylhydratropic Acid
CAS:<p>Impurity Ibuprofen EP Impurity N<br>Applications p-Ethylhydratropic Acid (Ibuprofen EP Impurity N) is a phenylacetic acid with potential antiinflammatory activities. p-Ethylhydratropic Acid is an impurity of Ibuprofen (I140000).<br></p>Fórmula:C11H14O2Forma y color:WhitePeso molecular:178.233-Hydroxy Medetomidine
CAS:Producto controlado<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Fórmula:C13H16N2OForma y color:NeatPeso molecular:216.28rac Ketorolac
CAS:Producto controlado<p>Applications Ketorolac is an analgesic; anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Fórmula:C15H13NO3Forma y color:Off White SolidPeso molecular:255.27rac-Ibuprofen Amide
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity C<br>Applications An impurity of Ibuprofen (I140000).<br>References Haikala, V., et al.: J. Pharm. Sci., 80, 456 (1991), Sochor, J., et al.: J. Pharm. Biomed. Anal., 13, 899 (1995),<br></p>Fórmula:C13H19NOForma y color:WhitePeso molecular:205.30Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Fórmula:C13H16N2Pureza:99.88%Forma y color:SolidPeso molecular:200.282′,4′,5′-Trifluoropropiophenone
CAS:Fórmula:C9H7F3OForma y color:Low Melting SolidPeso molecular:188.149(S)-Ketorolac
CAS:Producto controlado<p>Applications (S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.<br>References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982), Guzman, A., et al.: J. Med. Chem., 29, 589 (1986), McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986),<br></p>Fórmula:C15H13NO3Forma y color:NeatPeso molecular:255.27Acetaminophen Acetate (Acetaminophen Impurity)
CAS:<p>Impurity Paracetamol EP Impurity H/ Acetaminophen impurity H<br>Applications Acetaminophen Acetate is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C10H11NO3Forma y color:White To Off-WhitePeso molecular:193.20(-)-(3S)-3-Hydroxy Quinine
CAS:Producto controladoFórmula:C20H24N2O3Forma y color:NeatPeso molecular:340.42Desmethyl Ketoprofen
CAS:Producto controlado<p>Impurity Ketoprofen EP Impurity B<br>Applications Desmethyl Ketoprofen (Ketoprofen EP Impurity B) shows antiinflammatory and analgesic activities. It can be used as neoplasm inhibitors and for treatment of angiogenesis-related disorders.<br>References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).<br></p>Fórmula:C15H12O3Forma y color:WhitePeso molecular:240.25
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