Cetonas y Derivados
Las cetonas son compuestos orgánicos que contienen un grupo carbonilo (C=O) unido a dos átomos de carbono, formando una estructura en la que el grupo carbonilo está flanqueado por grupos alquilo o arilo. En farmacología, las cetonas se utilizan en la formulación de APIs debido a su capacidad para mejorar la solubilidad y estabilidad de los principios activos. Algunas cetonas tienen propiedades antiinflamatorias, analgésicas y antimicrobianas. Los derivados de cetonas incluyen compuestos en los que el grupo carbonilo está modificado, como los enoles, que tienen aplicaciones en la síntesis de fármacos y como intermediarios químicos en la fabricación de otros compuestos bioactivos. Los derivados de cetonas se utilizan en el diseño de nuevos medicamentos, incluidos aquellos para tratar enfermedades neurodegenerativas, trastornos metabólicos y ciertos tipos de cáncer, gracias a sus efectos específicos sobre enzimas y procesos celulares.
Se han encontrado 2394 productos de "Cetonas y Derivados"
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3-Methoxy Acetaminophen
CAS:<p>Applications 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C9H11NO3Forma y color:NeatPeso molecular:181.191-(5-Hydroxy-2-methylphenyl)ethanone
CAS:Pureza:95+%Forma y color:SolidPeso molecular:150.177001953125rac Ketoprofen-13C,d3
CAS:Producto controlado<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:CC152H3H11O3Forma y color:NeatPeso molecular:258.293-Acetylbenzophenone
CAS:<p>Impurity Ketoprofen EP Impurity A; Ketoprofen USP Related Compound D<br>Applications 3-Acetylbenzophenone (Ketoprofen EP Impurity A) is a Ketoprofen intermediate. Ketoprofen USP Related Compound D.<br>References Dvorak, J., et al.: J. Pharm. Biomed. Anal., 36, 625 (2004), Zhang, X., et al.: Bioorg. Med. Chem. Lett., 14, 1205 (2004),<br></p>Fórmula:C15H12O2Forma y color:Off-White To Light YellowPeso molecular:224.25rac N-Bisdesmethyl Tramadol, Hydrochloride
CAS:<p>Applications A metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Fórmula:C14H22ClNO2Forma y color:NeatPeso molecular:271.78(R)-(-)-Ketoprofen
CAS:Producto controlado<p>Applications Anti-inflammatory; analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990),<br></p>Fórmula:C16H14O3Forma y color:NeatPeso molecular:254.285'-Acetyl-2'-chloro-3-methyl-[1,1'-biphenyl]-4-carbaldehyde
CAS:Pureza:98%Peso molecular:272.7300109863281N-Benzyl Hydroxymedetomidine
CAS:Producto controlado<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Fórmula:C20H22N2OForma y color:NeatPeso molecular:306.4rac 1-Methoxy Ketorolac
CAS:Producto controlado<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Fórmula:C16H15NO4Forma y color:NeatPeso molecular:285.293-Benzoyl-α-methylbenzeneacetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F<br>Applications 3-Benzoyl-α-methylbenzeneacetonitrile (Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F) was used as a substrate to study the enantioselectivity of nitrile hydratase from Rhodococcus equi A4.<br>References Martinkova, L., et al.: Biotechnol. Lett. 18, 1073 (1996); Layh, N., et al.: Botehcnol. Lett. 17, 187 (1995);<br></p>Fórmula:C16H13NOForma y color:WhitePeso molecular:235.282-Chloronicotinic Acid
CAS:Producto controlado<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Fórmula:C6H4ClNO2Forma y color:NeatPeso molecular:157.55Ref: 10-F506307
1gA consultar2gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultar4-Isobutylbenzoic Acid
CAS:<p>Applications 4-Isobutylbenzoic Acid is used in the studies for the identification of the degradation products and potential impurities in Ibuprofen. 4-Isobutylbenzoic Acid is also applied in the determination of related substances in dexibuprofen using HPLC.<br>References Dondoni, A., et al.: Farmaco, Edizione Pratica, 41, 237 (1986); Xie, L., et al.: Zhongguo Yaoshi, 19, 1088 (2016)<br></p>Fórmula:C11H14O2Forma y color:NeatPeso molecular:178.23L-Lysine Clonixinate
CAS:<p>Applications L-Lysine Clonixinate is a non-morphinic andalgesic.<br>References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),<br></p>Fórmula:C13H11ClN2O2·C6H14N2O2Forma y color:Off WhitePeso molecular:408.88Acetaminophen Dimer-d6
CAS:Producto controlado<p>Applications Acetaminophen Dimer-d6 is deuterium labeled Acetaminophen Dimer (A161235). Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986)(3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H10D6N2O4Forma y color:NeatPeso molecular:306.35N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide
CAS:Producto controlado<p>Impurity Acetaminophen Impurity B<br>Applications N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide is an impurity of Acetaminophen (A161220), which is an analgesic and antipyretic (1,2,3,4). N-[5-(Acetylamino)-2-hydroxyphenyl]-N-(4-hydroxyphenyl)acetamide may be a useful reagent to investigate mechanisms related to liver and kidney damage from acetaminophen. Acetaminophen Impurity B.<br>References (1) Potter, D. W. and Hinson, J. A.: Drug Metab Rev. 20, 341 (1989) (2) Potter, D. W. and Hinson, J. A.: J. Biol. Chem. 260, 12174 (1985) (3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(4) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C16H16N2O4Forma y color:NeatPeso molecular:300.313′,5′-Dimethyl-4′-methoxyacetophenone
CAS:Fórmula:C11H14O2Pureza:97.0%Forma y color:SolidPeso molecular:178.231
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