Cetonas y Derivados
Las cetonas son compuestos orgánicos que contienen un grupo carbonilo (C=O) unido a dos átomos de carbono, formando una estructura en la que el grupo carbonilo está flanqueado por grupos alquilo o arilo. En farmacología, las cetonas se utilizan en la formulación de APIs debido a su capacidad para mejorar la solubilidad y estabilidad de los principios activos. Algunas cetonas tienen propiedades antiinflamatorias, analgésicas y antimicrobianas. Los derivados de cetonas incluyen compuestos en los que el grupo carbonilo está modificado, como los enoles, que tienen aplicaciones en la síntesis de fármacos y como intermediarios químicos en la fabricación de otros compuestos bioactivos. Los derivados de cetonas se utilizan en el diseño de nuevos medicamentos, incluidos aquellos para tratar enfermedades neurodegenerativas, trastornos metabólicos y ciertos tipos de cáncer, gracias a sus efectos específicos sobre enzimas y procesos celulares.
Se han encontrado 2394 productos de "Cetonas y Derivados"
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1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one
CAS:Pureza:97.0%Peso molecular:426.48800659179695'-Acetyl-2'-chloro-3-methyl-[1,1'-biphenyl]-4-carbaldehyde
CAS:Pureza:98%Peso molecular:272.73001098632813-Benzoyl-α-methylbenzeneacetonitrile
CAS:<p>Impurity Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F<br>Applications 3-Benzoyl-α-methylbenzeneacetonitrile (Ketoprofen EP Impurity F; Ketoprofen USP Related Compound F) was used as a substrate to study the enantioselectivity of nitrile hydratase from Rhodococcus equi A4.<br>References Martinkova, L., et al.: Biotechnol. Lett. 18, 1073 (1996); Layh, N., et al.: Botehcnol. Lett. 17, 187 (1995);<br></p>Fórmula:C16H13NOForma y color:WhitePeso molecular:235.284-Hydroxydiphenylamine
CAS:Producto controladoFórmula:C12H11NOForma y color:NeatPeso molecular:185.22rac-2’,4’,5’-Trimethyl Ketoprofen
CAS:Producto controlado<p>Applications rac-2,4’,5’-Trimethyl Ketoprofen is an impurity of Ketoprofen (K200800), an anti-inflammatory and analgesic agent.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976); Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981); Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990)<br></p>Fórmula:C19H20O3Forma y color:NeatPeso molecular:296.36Acetaminophen Dimer
CAS:<p>Applications Acetaminophen Dimer is an oxidatively couple dimer of Acetaminaphen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1). Acetaminophen Dimer along with other p-acetamidophenol analogs were used to determine peroxidase activities (2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Potter, D.W. et al.: Mol. Pharmacol., 29, 155 (1986) (3) Shiga, M. et al.: Anal. Sci., 11, 195 (1995)<br></p>Fórmula:C16H16N2O4Forma y color:NeatPeso molecular:300.31rac-Ketoprofen Tris Base Amide
CAS:Producto controlado<p>Applications rac-Ketoprofen Tris Base Amide is derived from rac Ketoprofen (K200800), which is an anti-inflammatory and analgesic.<br>References Ueno, K., et al.: J. Med. Chem., 19, 941 (1976), Liversidge, G.G., Anal. Profiles Drug Subs., 10, 443 (1981), Jamali, F., et al.: Clin. Pharmacokinet., 19, 197 (1990);<br></p>Fórmula:C20H23NO5Forma y color:NeatPeso molecular:357.15762285Quininone
CAS:<p>Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.<br>References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)<br></p>Fórmula:C20H22N2O2Forma y color:White To Light BeigePeso molecular:322.405-[1-(2,3-Dimethylphenyl)ethenyl]-1H-imidazole
CAS:Producto controladoFórmula:C13H14N2Forma y color:NeatPeso molecular:198.264'-Methylacetophenone
CAS:Producto controlado<p>Impurity Celecoxib Impurity<br>Applications 4'-Methylacetophenone is a methylated acteophenone used in cosmetics and perfumery. The presence of 4'-Methylacetophenone has been shown to accelerate the photopolymerization of Methyl methacrylate.<br>References Dwivedi, U.N. et al.: Acta Polym., 39, 596 (1988); Opdyke, D.L.J. et al.: Food Cosm. Toxicol., 12, 933 (1974);<br></p>Fórmula:C9H10OForma y color:NeatPeso molecular:134.184,5-Dimethyl-2-methoxyacetophenone
CAS:Fórmula:C11H14O2Pureza:95.0Forma y color:SolidPeso molecular:178.231(-)-Tramadol Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Fórmula:C16H25NO2·ClHForma y color:NeatPeso molecular:299.84Flufenamic Acid-d4
CAS:Producto controladoFórmula:C14H6D4F3NO2Forma y color:NeatPeso molecular:285.25N-(1-Phenylethyl) Ibuprofen Amide(Mixture of 4 Diastereomers)
CAS:Producto controlado<p>Applications Ibuprofen (I140000) impurity, an anti-inflammatory compound.<br>References Rubin, A., et al.: J. Pharm. Sci., 74, 82 (1985), Tracy, T., et al.: Drug Metab. Dispos., 20, 322 (1992),<br></p>Fórmula:C21H27NOForma y color:WhitePeso molecular:309.456-Methoxy-2-naphthaleneacetic Acid-d3 (Desmethyl Naproxen-d3)
CAS:Producto controlado<p>Applications A labelled metabolite of Nabumetone (N200500). A competitive, non-selective COX inhibitor.<br>References Turpeinen et. al.: Drug Metabolism and Dispositoin, 37: 1017 (2009); Daniels, F., et al.: J. Invest. Dermatol., 44, 259 (1965), Bosca, F., et al.: Photochem. Photobiol., 71, 173 (2000),<br></p>Fórmula:C13H9D3O3Forma y color:White To Off-WhitePeso molecular:219.25Acetaminophen-cysteine
CAS:Producto controladoFórmula:C11H14N2O3SForma y color:NeatPeso molecular:254.315-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide, racemic
CAS:<p>5-Benzoyl-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-2,3-dihydro-1H-pyrrolizine-1-carboxamide is a drug product that is used in research and development. It is a synthetic compound with niche applications. It has been shown to be metabolized in animal studies and the metabolism pathways have been elucidated. The analytical impurity standard for this drug product is 5-(benzoylamino)-N-[2-(hydroxymethyl)propanoyl]-2,3,-dihydro-1H-pyrrolizine-1 -carboxamide. This compound can be custom synthesized and also has an HPLC standard available.</p>Fórmula:C19H22N2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:358.39 g/molParacetamol Impurity L
<p>Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.</p>Fórmula:C16H16N2O4Pureza:Min. 95%Peso molecular:300.31 g/mol5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic
CAS:<p>5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic is a drug product that is used for the research and development of drugs. It is manufactured synthetically. This compound has been shown to be metabolized in rats and humans. Studies have also shown that this compound may be an impurity in other drugs. The use of 5-Benzoyl-7-bromo-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic can be found in the USP/NF as a HPLC standard or as an analytical reference standard.</p>Fórmula:C15H12BrO3NPureza:Min. 95%Peso molecular:334.16 g/mol
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