
Derivados de Benzimidazol e Imidazol
El benzimidazol es un compuesto que consta de un anillo bencénico fusionado a un anillo imidazol, una estructura de cinco miembros que contiene dos átomos de nitrógeno. Los derivados de benzimidazol, como el albendazol, son conocidos por su actividad antiparasitaria y antifúngica, utilizados en el tratamiento de infecciones parasitarias y en algunas enfermedades parasitarias en animales y humanos. El imidazol, por su parte, es una estructura de cinco miembros con dos átomos de nitrógeno, que se encuentra en diversos compuestos biológicamente activos. Los derivados de imidazol, como el metronidazol, tienen propiedades antimicrobianas y antiparasitarias. Estos compuestos también se usan en la industria farmacéutica para tratar infecciones bacterianas, enfermedades parasitarias y algunas infecciones fúngicas, además de tener aplicaciones en la química orgánica como catalizadores.
En CymitQuimica ofrecemos benzimidazoles e imidazoles de alta pureza para investigación en química medicinal, farmacología y biotecnología.
Se han encontrado 10337 productos de "Derivados de Benzimidazol e Imidazol"
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2-Deschlorothien-3-yl Tioconazole Hydrochloride
CAS:Producto controlado<p>Applications 2-Deschloro Tioconazole Hydrochloride is an analog of Tioconazole (T444680), an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).<br>References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),<br></p>Fórmula:C16H14Cl2N2OS·ClHForma y color:NeatPeso molecular:389.73Metopimazine
CAS:<p>Applications Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Fórmula:C22H27N3O3S2Forma y color:Off White SolidPeso molecular:445.60(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Producto controladoFórmula:C13H15F2N3O4SForma y color:NeatPeso molecular:347.34(Chloromethyl)cyclohexane
CAS:Producto controlado<p>Applications (Chloromethyl)cyclohexane is a common chemical reagent used in the synthesis of imidazole inhibitors of cytokine release which suppresses the response to tumor necrosis factor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laufer, S. et al., J. Med. Chem., 45, 1695 (2002); Rabinowitz, M. et al.: J. Med. Chem., 44, 4252 (2001);<br></p>Fórmula:C7H13ClForma y color:NeatPeso molecular:132.63Triazolam-d3
CAS:Producto controlado<p>Applications Labelled Triazolam (T767380(M)). Triazolam in an hypnotic drug used in the short term treatment of insomnia.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981).<br></p>Fórmula:C17H9D3Cl2N4Forma y color:NeatPeso molecular:346.231,3-Diethyl 2-(1-cyano-3-methylbutyl)propanedioate
CAS:Producto controladoFórmula:C13H21NO4Forma y color:NeatPeso molecular:255.314-Hydroxy Midazolam-d5 Methanoate
CAS:Producto controlado<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Fórmula:C19H12D5ClFN3O2Forma y color:NeatPeso molecular:378.844,4'-(Bromomethylene)dibenzonitrile
CAS:Producto controlado<p>Applications 4,4'-(1-Bromomethyl)bis-benzonitrile (CAS# 69545-39-7) is a useful research chemical compound.<br></p>Fórmula:C15H9BrN2Forma y color:NeatPeso molecular:297.149(S)-Modafinil-d10
CAS:Producto controlado<p>Applications Labelled (S)-Modafinil. Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Fórmula:C15D10H5NO2SForma y color:NeatPeso molecular:283.412-Cyclopropylmethylamino-5-chlorobenzophenone
CAS:Producto controlado<p>Applications: 2-Cyclopropylmethylamino-5-chlorobenzophenone is a benzodiazepine derivative.<br>References Japp, M. et al.: J. Chrom., 439, 317 (1988); Guan, F. et al.: J. Anal Toxicol., 23, 54 (1999);<br></p>Fórmula:C17H16ClNOForma y color:NeatPeso molecular:285.772,5-Dichlorobenzoyl Cyanide
CAS:Producto controlado<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Fórmula:C8H3Cl2NOForma y color:NeatPeso molecular:200.022(2-Chlorophenyl)diphenylmethane
CAS:Producto controlado<p>Applications (2-Chlorophenyl)diphenylmethane is a triarylmethane with antiproliferative activity. (2-Chlorophenyl)diphenylmethane is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Al-Qawasmeh, R.A. et al.: Bioorg. Med. Chem. Lett., 14, 347 (2004);<br></p>Fórmula:C19H15ClForma y color:NeatPeso molecular:278.784,9-Diisobutyl-1,6-diazecane-2,7-dione
CAS:Producto controlado<p>Applications 4,9-Diisobutyl-1,6-diazecane-2,7-dione is in impurity of rac-Pregabalin (P704800) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Fórmula:C16H30N2O2Forma y color:NeatPeso molecular:282.42N-Nitrosoiminodibenzyl
CAS:Producto controladoFórmula:C14H12N2OForma y color:NeatPeso molecular:224.264-Methyl-2-[3-[(1-methylethyl)nitrosoamino]-1-phenylpropyl]phenol
CAS:Producto controladoFórmula:C19H24N2O2Forma y color:NeatPeso molecular:312.418-Demethyl Zolazepam
CAS:Producto controlado<p>Applications N-Demethylated metabolite of the anesthetic agent, Zolazepam (Z613500).<br>References Baukema, J. et al.: Res. Comm. Chem. Pathol. Pharmacol., 10, 227 (1975);<br></p>Fórmula:C14H13FN4OForma y color:NeatPeso molecular:272.282,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Producto controlado<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Fórmula:C11H16N4O2Forma y color:NeatPeso molecular:236.27Metopimazine-d6
CAS:Producto controlado<p>Applications Labelled Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Fórmula:C22H21D6N3O3S2Forma y color:NeatPeso molecular:451.64(3S)-3-(2-Methylpropyl)-pentanedioic Acid 1-Methyl Ester
CAS:Producto controlado<p>Impurity Pregabalin Impurity 17<br>Applications (3S)-3-(2-Methylpropyl)-pentanedioic Acid 1-Methyl Ester (Pregabalin Impurity 17) is an impurity of Pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Fórmula:C10H18O4Forma y color:NeatPeso molecular:202.25(S)-Rivastigmine
CAS:<p>Applications S-Rivastigmine is an isomer of Rivastigmine ( an acetylcholinesterase inhibitor used in the treatment of neurological disorders such as Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Howes, L et al.: Drug. Safe., 37, 391 (2014); Shahar, O. et al.: Nucl. Acids Res., 42, 5869 (2014);<br></p>Fórmula:C14H22N2O2Forma y color:ColourlessPeso molecular:250.34Hydroxy Varenicline N-Trifluoroacetic Acid Salt
CAS:Producto controlado<p>Applications Protected Varenicline metabolite.<br></p>Fórmula:C15H12F3N3O2Forma y color:NeatPeso molecular:323.27Propyl Itraconazole
CAS:Producto controladoFórmula:C34H36Cl2N8O4Forma y color:NeatPeso molecular:691.61Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity
CAS:Producto controlado<p>Applications Itraconazole Desethylene-seco-piperazine Di-N-formyl Impurity is a by-product in the synthesis of Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity (I937520), which is an impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Fórmula:C35H36Cl2N8O6Forma y color:NeatPeso molecular:735.62Prazepam
CAS:Producto controlado<p>Applications Prazepam, is a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Fórmula:C19H17ClN2OForma y color:Off-WhitePeso molecular:324.803,4-Dihydro-1-phenylisoquinoline Hydrochloride
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications 3,4-Dihydro-1-phenylisoquinoline has been shown to have anesthetic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moore, M.B., et. al.: J. Am. Chem. Soc., 76, 3656 (1954)<br></p>Fórmula:C15H13N·ClHForma y color:NeatPeso molecular:243.73Lormetazepam
CAS:Producto controlado<p>Applications An analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant).<br>References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),<br></p>Fórmula:C16H12Cl2N2O2Forma y color:Light Yellow To Light GreenPeso molecular:335.18Nitroguanidine (Wetted with water >20%)
CAS:Producto controlado<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:CH4N4O2Forma y color:White To Off-WhitePeso molecular:104.07Temazepam
CAS:Producto controlado<p>Applications Temazepam is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Fórmula:C16H13ClN2O2Forma y color:Light YellowPeso molecular:300.74Isometronidazole-D4
CAS:Producto controlado<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Fórmula:C6D4H5N3O3Forma y color:NeatPeso molecular:175.18trans-Itraconazole
CAS:Producto controlado<p>Impurity Itraconazole EP Impurity E<br>Applications trans-Itraconazole (Itraconazole EP Impurity E) is a geometrical isomer of Itraconazole (I937500). It is a COVID19-related research product.<br>References Ahn, C., et al.: J. Korean Chem. Soc., 43, 676 (1999),<br></p>Fórmula:C35H38Cl2N8O4Forma y color:NeatPeso molecular:705.63Noratropine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Atropine (A794625). Two metabolites of Atropine (apoatropine and noratropine) were found in rat urine.<br>References Xu, A., et al.: J. Pharm. Biomed. Anal., 14, 33 (1995), Cherkaoui, S., et al.: J. Pharm. Biomed. Anal., 17, 1167 (1998),<br></p>Fórmula:C16H21NO3·HClForma y color:BrownPeso molecular:311.8010-Methoxy-5H-dibenz[b,f]azepine-5-carbonyl chloride
CAS:Producto controladoFórmula:C16H12ClNO2Forma y color:NeatPeso molecular:286.002-(Chloromethyl)-3,5-dimethylpyridine Hydrochloride
CAS:Producto controlado<p>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Fórmula:C8H10ClN·ClHForma y color:NeatPeso molecular:192.092,2'-Ethylenedianiline
CAS:Producto controlado<p>Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.<br>References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)<br></p>Fórmula:C14H16N2Forma y color:NeatPeso molecular:212.291-Chloro-2-(dichlorophenylmethyl)benzene
CAS:Producto controlado<p>Applications 1-Chloro-2-(dichlorophenylmethyl)benzene is an intermediate used in the preparation of 2-chlorotrityl chloride resins. 1-Chloro-2-(dichlorophenylmethyl)benzene is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Li, P. et al.: Guoch. Gong. Xue., 9, 558 (2009);<br></p>Fórmula:C13H9Cl3Forma y color:Light YellowPeso molecular:271.57(S)-Aclidinium Bromide
CAS:Producto controlado<p>Applications (S)-Aclidinium Bromide is an isomer of Aclidinium Bromide (A190180) a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease (1,2).<br>References (1) Gupta, V. and Singh, D.: Expert Rev Respir Med. 6, 581 (2012)(2) De La Motte, S., et al.: Int. J. Clin. Pharmacol. Therap., 50,403 (2012)<br></p>Fórmula:C26H30BrNO4S2Forma y color:Off-WhitePeso molecular:564.551',4-Dihydroxy Midazolam
CAS:Producto controlado<p>Applications A metabolite of Midazolam (M343000).<br>References Soucek, P., et al.: Xenobiotica, 22, 83 (1992), Ghosal, A., et al.: Drug Metab. Dispos., 24, 940 (1996), Kobayashi, K., et al.: Biochem. Pharmacol., 63, 889 (2002),<br></p>Fórmula:C18H13ClFN3O2Forma y color:NeatPeso molecular:357.773-Isobutylglutaric Anhydride
CAS:Producto controladoFórmula:C9H14O3Forma y color:NeatPeso molecular:170.20574-Nitro-5-desnitro Tinidazole
CAS:Producto controlado<p>Impurity Tinidazole EP Impurity B<br>Applications 4-Nitro-5-desnitro Tinidazole (Tinidazole EP Impurity B) is an impurity in the synthesis of Tinidazole (T443900), antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Fórmula:C8H13N3O4SForma y color:NeatPeso molecular:247.27Isopropyl Itraconazole
CAS:Producto controladoFórmula:C34H36Cl2N8O4Forma y color:NeatPeso molecular:691.61ent-Voriconazole
CAS:Producto controlado<p>Impurity Voriconazole EP Impurity D; Voriconazole USP Related Compound B<br>Applications ent-Voriconazole (Voriconazole USP Related Compound B; Voriconazole EP Impurity D) is the (2S,3R) enantiomer in Voriconazole (V760000) drug substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gage, R., et al.: J. Pharm. Biomed. Anal., 17, 1449 (1998), Owens, P., et al.: Enantiomer, 4, 79 (1999), Pehourcq, F., et al.: Biomed. Chromatogr., 18, 719 (2004), Sellers, J., et al.: J. Pharm. Biomed. Anal., 41, 1088 (2006),<br></p>Fórmula:C16H14F3N5OForma y color:NeatPeso molecular:349.314-Chloro-6-ethyl-5-fluoropyrimidine
CAS:Producto controlado<p>Applications A pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Fórmula:C6H6ClFN2Forma y color:NeatPeso molecular:160.58N-Ethylcarbamic Acid 3-[(1S)-1-(Dimethylamino)ethyl]phenyl Ester
CAS:Producto controladoFórmula:C13H20N2O2Forma y color:NeatPeso molecular:236.31Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Producto controlado<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Fórmula:C34H36Cl2N8O5Forma y color:NeatPeso molecular:707.614'-Desmethoxy Omeprazole
CAS:Producto controlado<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Fórmula:C16H17N3O2SForma y color:NeatPeso molecular:315.39Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Fórmula:C28H38N4O3SForma y color:NeatPeso molecular:510.694-Hydroxy Triazolam
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications A metabolite of Triazolam (T767380).<br>References Gall, M., et al.: J. Med. Chem., 21, 1290 (1978), Jones, H., et al.: Drug Metab. Dispos., 32, 973 (2004), Hallifax, D., et al.: Drug Metab. Dispos., 33, 1852 (2005).<br></p>Fórmula:C17H12Cl2N4OForma y color:NeatPeso molecular:359.21cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Producto controlado<p>Applications Solifenacin (S676700) metabolite.<br></p>Fórmula:C23H26N2O4Forma y color:NeatPeso molecular:394.46(S)-5,6-Dehydro Pregabalin
CAS:Producto controlado<p>Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Fórmula:C8H15NO2Forma y color:NeatPeso molecular:157.21Butyl Itraconazole
CAS:Producto controladoFórmula:C35H38Cl2N8O4Forma y color:NeatPeso molecular:705.63Prazepam-d5
CAS:Producto controlado<p>Applications Prazepam-d5, is the labeled analogue of Prazepam (P702250), a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Fórmula:C192H5H12ClN2OForma y color:NeatPeso molecular:329.832-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
CAS:Producto controlado<p>Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.<br>References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);<br></p>Fórmula:C8H10ClNO·ClHForma y color:NeatPeso molecular:208.08Solifenacin EP Impurity A Nitroso Impurity
Producto controladoFórmula:C15H14N2OForma y color:NeatPeso molecular:238.296-Ethyl-5-fluoropyrimidin-4(3H)-one
CAS:Producto controlado<p>Applications A pyrimidine derivative used in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Fórmula:C6H7FN2OForma y color:NeatPeso molecular:142.13β-Ketoglutaric Acid
CAS:<p>Stability Unstable in Solution<br>Applications β-Ketoglutaric Acid is used in the synthesis of benzodiazepine derivatives. Also used in the synthesis of orally available hepatitis C virus polymerase inhibitors.<br>References Jung, D. et al.: Synth. Comm., 29, 1941 (1999); Li, H. et al.: J. Med. Chem., 52, 1255 (2009);<br></p>Fórmula:C5H6O5Forma y color:Off White PowderPeso molecular:146.0981,2-Bismethylenecyclohexane (~75%)
CAS:Producto controladoFórmula:C8H12Pureza:~75%Forma y color:NeatPeso molecular:108.182-Amino-5-benzoyl-1-methylbenzimidazole
CAS:Producto controlado<p>Applications Mebendazole (M200500) thermal decomposition product. Mebendazole impurity.<br>References Himmelreich, M., et al.: Aus. J. Pharmaceut. Sci., 6, 123 (1977),<br></p>Fórmula:C15H13N3OForma y color:NeatPeso molecular:251.28(3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl Acetate
CAS:Producto controlado<p>Impurity Lansoprazole<br>Applications (3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl Acetate is an impurity of Lansoprazole (L175000). Lansoprazole is used as a gastric proton pump inhibitor and an antiulcerative. It May limit the severity of tuberculosis.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000); Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001); Barradell, L.B., et al.: Drugs, 44, 225 (1992); Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002); Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006); Chem. and Eng. News. p. 28 July 20 (2018)<br></p>Fórmula:C11H12F3NO3Forma y color:NeatPeso molecular:263.213(R)-4,5-Dehydro Pregabalin
CAS:Producto controlado<p>Applications (R)-4,5-Dehydro Pregabalin is derived from rac 4,5-Dehydro Pregabalin (D230050), which is an impurity of the anti-convulsnat, Pregabalin.<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Fórmula:C8H15NO2Forma y color:NeatPeso molecular:157.21Tiotropium-d6 Bromide
CAS:Producto controladoFórmula:C19H16D6BrNO4S2Forma y color:White To PurplePeso molecular:478.452-[2-(2-Methyl-4-nitroimidazol-1-yl)ethoxy]ethanol
CAS:Producto controladoFórmula:C8H13N3O4Forma y color:NeatPeso molecular:215.21(alphaS)-N,N,α-Trimethyl-3-(4-nitrophenoxy)benzenemethanamine
CAS:Producto controlado<p>Applications (αS)-N,N,α-Trimethyl-3-(4-nitrophenoxy)benzenemethanamine is an impurity of Rivastigmine Tartrate (R541000). Rivastigmine Tartrate is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999); Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Fórmula:C16H18N2O3Forma y color:OrangePeso molecular:286.33Lansoprazole Sulfone N-Oxide
CAS:Producto controlado<p>Applications An impurity of Lansoprazole.<br>References Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006), El-Sherif, Z., et al.: Chem. Pharm. Bull., 54, 814 (2006),<br></p>Fórmula:C16H14F3N3O4SForma y color:WhitePeso molecular:401.36N-Desmethyl Dextrorphan β-D-O-Glucuronide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A labelled metabolite of Dextromethorphan.<br>References Gonzalez, F., et al.: Nature, 331, 442 (1988), Chen, S., et al.: Clin. Pharmacol. Ther., 60, 522 (1996), Hartter, S., et al.: Ther. Drug Monit., 18, 297 (1996), Garcia-Martin, E., et al.: Clin. Pharmacol. Ther., 71, 196 (2002),<br></p>Fórmula:C22H29NO7Forma y color:NeatPeso molecular:419.47Modafinil-d5 Sulfone
CAS:Producto controlado<p>Applications A labelled metabolite of Modafinil (M482500), a central nervous system vigilance promoting agent, which possesses neuroprotective properties.<br>References Wong, Y., et al.: J. Clin. Pharmacol., 39, 281 (1999), Robertson, P., et al.: Drug Metab. Dispos., 28, 664 (2000), Roth, T., et al.: Clin. Ther., 28, 689 (2006),<br></p>Fórmula:C152H5H10NO3SForma y color:NeatPeso molecular:294.384-Acetoxy Midazolam
CAS:Producto controlado<p>Applications A metabolite of Midazolam (M343000).<br></p>Fórmula:C20H15ClFN3O2Forma y color:NeatPeso molecular:383.801-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid Sodium Salt
CAS:<p>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid is an impurity of Rabeprazole. It is also a degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999); Carswel, C., et al.: Drugs, 61, 2327 (2001); Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008)<br></p>Fórmula:C14H10N3NaO3Forma y color:NeatPeso molecular:291.24α-Methyl-phenothiazine-10-ethanol
CAS:Producto controlado<p>Applications A promethazine (P757000) metabolite.<br>References Clement, B. A. & Beckett, A. H.; Xenobiotica 11, 609 (1981)<br></p>Fórmula:C15H15NOSForma y color:NeatPeso molecular:257.359-Acridinecarboxylic acid
CAS:Producto controlado<p>Applications 9-Acridinecarboxylic acid is used in the synthesis of short DNA-binding peptides.<br></p>Fórmula:C14H9NO2Forma y color:YellowPeso molecular:223.231-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%)
CAS:<p>Impurity Rabeprazole EP Impurity C<br>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%) (Rabeprazole EP Impurity C) is a Rabeprazole (R070500) impurity. A degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999), Carswel, C., et al.: Drugs, 61, 2327 (2001), Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008),<br></p>Fórmula:C14H11N3O3Pureza:>75%Forma y color:NeatPeso molecular:269.26Scopolamine β-D-Glucuronide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Scopolamine.<br>References Shutt, L., et al.: Anaesthesia, 34, 476 (1979), Wada, S., et al.: Xenobiotica, 21, 1289 (1991), Chen, X., et al.: Acta Pharm. Sin., 33, 849(1998),<br></p>Fórmula:C23H29NO10Pureza:>85%Forma y color:NeatPeso molecular:479.484-Fluorobenzonitrile
CAS:Producto controlado<p>Applications 4-Fluorobenzonitrile is used in the synthesis of flurenones, pharmaceutical prerequisites, as well as opiod receptor antagonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wan, J. et al.: Org. Lett., 15, 2742 (2013); Kormos, C. et al.: J. Med. Chem., 56, 4551 (2013);<br></p>Fórmula:C7H4FNForma y color:NeatPeso molecular:121.112-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
CAS:Producto controlado<p>Impurity Itraconazole EP Impurity A<br>Applications 2-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one (Itraconazole EP Impurity A) is an intermediate of Itraconazole.<br></p>Fórmula:C23H29N5O2Forma y color:BeigePeso molecular:407.51Varenicline Carbamoyl β-D-Glucuronide
CAS:Producto controlado<p>Applications A metabolite of Varenicline.<br>References Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005), Obach, R., et al.: Drug Metab. Dispos., 33, 262 (2005),<br></p>Fórmula:C20H21N3O8Forma y color:NeatPeso molecular:431.4N-Desethyl N-Methyl rac-Rivastigmine
CAS:<p>Impurity Rivastigmin USP Related Compound B<br>Applications N-Desethyl N-Methyl rac-Rivastigmine (Rivastigmin USP Related Compound B) is an impurity in the synthesis of Rivastigmine (R541000) a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Fórmula:C13H20N2O2Forma y color:Clear ColourlessPeso molecular:236.312-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride
CAS:Producto controlado<p>Impurity Omeprazole EP Impurity XI<br>Applications 2-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride (Omeprazole EP Impurity XI) is an intermediate in the production of the antiulcer agent Omeprazole.<br>References Roma, G., et al.: J. Med. Chem., 50, 2886 (2007), Hoffmann, S., et al.: Toxicol. Lett., 180, 9 (2008),<br></p>Fórmula:C9H12ClNO·ClHForma y color:WhitePeso molecular:222.116-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS:Producto controlado<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Fórmula:C15H10ClFN2Forma y color:NeatPeso molecular:272.7010-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide
CAS:Producto controlado<p>Impurity Carbamazepine EP Impurity G<br>Applications 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide is a Carbamazepine (C175840(P)) impurity, which has been used in treatment of pain associated with trigeminal neuralgia. It is an anticonvulsant, neuroprotective & neuroresearch product.<br>References Cry, T., et. al.: J. Assoc. Official Anal. Chem., 70, 836 (1987); Stenger, E.G., et al.: Med. Exp., 11, 191 (1964); Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979); Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Fórmula:C15H11BrN2OForma y color:NeatPeso molecular:315.16rac-6-Chloro Voriconazole
CAS:Producto controlado<p>Applications An achiral intermediate of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferretti, R., et al.: Chromatographia, 47, 649 (1998),<br></p>Fórmula:C16H13ClF3N5OForma y color:NeatPeso molecular:383.76Trimebutine-d9 Maleate Salt
CAS:Producto controlado<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Fórmula:C22H20D9NO5·C4H4O4Forma y color:NeatPeso molecular:512.6(E)-Ethyl 2-cyano-5-methylhex-2-enoate
CAS:Producto controladoFórmula:C10H15NO2Forma y color:NeatPeso molecular:335.4294-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
CAS:Producto controlado<p>Applications 4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.<br></p>Fórmula:C19H21N5O2Forma y color:NeatPeso molecular:351.40Metronidazole β-D-Glucuronide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Metronidazole.<br>References Kokwaro, G.O., et al.: Biochem. Pharmacol., 45, 1243 (1993), Sidelmann, U.G. , et al.: Xenobiotica, 26, 709 (1996),<br></p>Fórmula:C12H17N3O9Forma y color:NeatPeso molecular:347.2810-Chloro Carbamazepine
CAS:<p>Applications 10-Chloro Carbamazepine is a derivative of Carbamazepine (C175840) which is used in treatment of pain associated with trigeminal neuralgia.<br>References Stenger, E.G., et al.: Med. Exp., 11, 191 (1964), Pynnonen, S., et al.: Ther. Drug Monit., 1, 409 (1979), Sidebottom, A., et al.: J. Clin. Pharm. Ther., 20, 31 (1995)<br></p>Fórmula:C15H11ClN2OForma y color:White PowderPeso molecular:270.71N-Carbamoyl Carbamazepine
CAS:Producto controlado<p>Impurity Carbamazepine EP Impurity C<br>Applications Carbamazepine (C175840) impurity.<br></p>Fórmula:C16H13N3O2Forma y color:NeatPeso molecular:279.29Midazolam-d6 (1 mg/mL in Acetonitrile)
CAS:Producto controladoFórmula:C18D6H7ClFN3Forma y color:Single SolutionPeso molecular:331.80cis-Hydroxy Solifenacin (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Solifenacin (S676700) metabolite.<br>References Naito, R., et al.: J. Med. Chem., 48, 6597 (2005), Krauwinkel, W., et al.: Int. J. Clin. Pharmacol. Ther., 43, 227 (2005),<br></p>Fórmula:C23H26N2O3Forma y color:NeatPeso molecular:378.46Benzofuran-6-carboxylic Acid
CAS:Producto controlado<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Fórmula:C9H6O3Forma y color:NeatPeso molecular:162.14(2Z)-2-[Cyano(2,3-dichlorophenyl)methylene]hydrazinecarboximidamide
CAS:Producto controladoFórmula:C9H7Cl2N5Forma y color:NeatPeso molecular:256.092-(Ethylthio)ethanol
CAS:Producto controlado<p>Applications 2-(Ethylthio)ethanol is used to prepare aryldihydropyrimidinones as inhibitors of fatty acid transporter FATP4.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Blackburn, C., et al.: Bioorg. Med. Chem. Lett., 16, 3504 (2006)<br></p>Fórmula:C4H10OSForma y color:NeatPeso molecular:106.19Scopolamine Sulfate
CAS:Producto controlado<p>Applications Scopolamine Sulfate is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trendelenburg P., et al.: Archiv fuer Exper. Pathol. Pharmacol., 73, 118 (1914);<br></p>Fórmula:C17H21NO7SForma y color:NeatPeso molecular:383.423-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Producto controlado<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Fórmula:C8H16BrNOForma y color:NeatPeso molecular:222.12N-trifluoroacetyl Varenicline
CAS:Producto controlado<p>Applications 7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine is used to prepare varenicline, which is a smoking cessation. It is a Varenicline protected impurity.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005) ;<br></p>Fórmula:C15H12F3N3OForma y color:NeatPeso molecular:307.2705Propantheline-d3 Iodide
CAS:Producto controlado<p>Applications Labelled Propantheline (P760900). Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Fórmula:C23H27D3INO3Forma y color:NeatPeso molecular:498.412-Chloroacetamide
CAS:Producto controlado<p>Applications A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aptula, A., et al.: Chem. Res. Toxicol., 19, 1097 (2006), Chan, K., et al.: J. Appl. Toxicol., 28, 608 (2008),<br></p>Fórmula:C2H4ClNOForma y color:WhitePeso molecular:93.512-Chlorobenzotrichloride
CAS:Producto controlado<p>Applications 2-Chlorobenzotrichloride is a chlorinated toluene with mutagenicity.<br>References Mineki, S. et al.: Mat. technol., 23, 413 (2005); Matsushita, H. et al.: Indust. Health., 17, 199 (1979);<br></p>Fórmula:C7H4Cl4Forma y color:NeatPeso molecular:229.92
