Derivados de Benzimidazol e Imidazol
El benzimidazol es un compuesto que consta de un anillo bencénico fusionado a un anillo imidazol, una estructura de cinco miembros que contiene dos átomos de nitrógeno. Los derivados de benzimidazol, como el albendazol, son conocidos por su actividad antiparasitaria y antifúngica, utilizados en el tratamiento de infecciones parasitarias y en algunas enfermedades parasitarias en animales y humanos. El imidazol, por su parte, es una estructura de cinco miembros con dos átomos de nitrógeno, que se encuentra en diversos compuestos biológicamente activos. Los derivados de imidazol, como el metronidazol, tienen propiedades antimicrobianas y antiparasitarias. Estos compuestos también se usan en la industria farmacéutica para tratar infecciones bacterianas, enfermedades parasitarias y algunas infecciones fúngicas, además de tener aplicaciones en la química orgánica como catalizadores.
En CymitQuimica ofrecemos benzimidazoles e imidazoles de alta pureza para investigación en química medicinal, farmacología y biotecnología.
Se han encontrado 10345 productos de "Derivados de Benzimidazol e Imidazol"
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4-Desmethoxypropoxyl-4-chloro Rabeprazole
CAS:Producto controlado<p>Impurity Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)<br>Applications 4-Desmethoxypropoxyl-4-chloro Rabeprazole (Rabeprazole EP Impurity H (Lansoprazole EP Impurity F)) is a process impurity of Rabeprazole (R070500).<br></p>Fórmula:C14H12ClN3OSForma y color:NeatPeso molecular:305.782-Methoxy-5-methyl-N,N-bis(1-methylethyl)-γ-phenyl-benzenepropanamine (2E)-2-Butenedioate
CAS:Producto controlado<p>Impurity Tolterodine USP Related Compound A<br>Applications 2-Methoxy-5-methyl-N,N-bis(1-methylethyl)-γ-phenyl-benzenepropanamine (2E)-2-Butenedioate (Tolterodine USP Related Compound A) is a related compound of Tolterodine (T535795), a muscarinic receptor antagonist.<br>References Nilvebrant, L., et al.: Life Sci., 60, 1129 (1997), Nilvebrant, L., et al.: Eur. J. Pharmacol., 327, 195 (1997), Brynne, N., et al.: Int. J. Clin. Pharmacol. Ther., 35, 287 (1997)<br></p>Fórmula:C23H33NO·(C4H4O4)Forma y color:NeatPeso molecular:339.51 + (116.07)1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Fórmula:C26H35NO5Pureza:>90%Forma y color:NeatPeso molecular:441.56Lifitegrast
CAS:Producto controlado<p>Applications Lifitegrast is used for the treatment of signs and symptons of dry eye diseases. It also Inhibites corneal inflammation that is capable of causing pains, blurred vision and ocular discomfort in sufferer.<br>References Holland, E. J., et al.: Curr. Med. Res. Opin., 32, 1759 (2016); Sun, Y., et al.: J. Ocul. Pharmacol. Ther., 29, 395 (2013);<br></p>Fórmula:C29H24Cl2N2O7SForma y color:White To Off-WhitePeso molecular:615.481Tropicamide
CAS:<p>Applications Ophthalmic anticholinergic. Mydriatic.<br>References Blessel, K.W., et al.: Anal. Profiles Drug Subs., 3, 565 (1974), Krapivinsky, G., et al.: J. Biol. Chem., 270, 29059 (1995), Bedingfield, J., et al.: Eur. J. Pharmacol., 309, 71 (1996), Jin, W., et al.: Biochemistry, 38, 14294 (1999), Kew, J., et al.: Pharmacol. Ther., 104, 233 ( 2004), Bertaso, F., et al.: J. Neurochem., 99, 288 (2006),<br></p>Fórmula:C17H20N2O2Forma y color:NeatPeso molecular:284.353-(2-(6-(tert-Butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutanone hydrochloride
CAS:Pureza:97.0%Peso molecular:306.8299865722656Methyl 2-Oxo-1-pyrrolidineacetate
CAS:<p>Applications Methyl 2-Oxo-1-pyrrolidineacetate is used a reagent in the synthesis of benzoquinolizidine and benzoindolizidine derivatives as anti-amnesic agents. It is also used as a a reagent in the synthesis of (acylamino)acridines as choline uptake enhancers.<br>References Zhao, S., et al.: Bioorg. Med. Chem., 7, 1637 (1999); Chaki, H., et al.: Bioorg. Med. Chem. Lett., 5, 1489 (1995)<br></p>Fórmula:C7H11NO3Forma y color:ColourlessPeso molecular:157.17Tinidazole
CAS:Producto controlado<p>Applications Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Fórmula:C8H13N3O4SForma y color:Off-White To Light YellowPeso molecular:247.275-Benzoyl-1,3-dihydro-2H-benzimidazol-2-one
CAS:Producto controlado<p>Applications This compound contains a benzimidazolone moiety which has been seen to inhibit p38 MAP kinase , a crucial protein in the activation of biological factors related to psoriasis, rheumatoid arthritis and other inflammatory diseases.<br>References Hammach, A. et al.: Bioorg. Med. Chem. Lett., 16, 6316 (2006);<br></p>Fórmula:C14H10N2O2Forma y color:NeatPeso molecular:238.2410-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Producto controlado<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Fórmula:C17H14N2O3Forma y color:NeatPeso molecular:294.302-Methyl-5-nitroimidazole
CAS:<p>Impurity Tinidazole EP Impurity A/ Metronidazole EP Impurity A<br>Applications 2-Methyl-5-nitroimidazole (Tinidazole EP Impurity A) is a Floconazole impurity.<br>References Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009), Kumar, L., et al.: Eur. J. Med. Chem., 45, 817 (2010),<br></p>Fórmula:C4H5N3O2Forma y color:Light YellowPeso molecular:127.10Triazolam N-Oxide
CAS:Producto controlado<p>Applications Triazolam N-Oxide is a derivative of Triazolam (T767380), a sedative.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976); Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978); Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Fórmula:C17H12Cl2N4OForma y color:NeatPeso molecular:359.21{[4-(1H-benzimidazol-2-yl)cyclohexyl]methyl}amine dihydrochloride
CAS:Pureza:95.0%Peso molecular:302.239990234375Oxazepam-d5
CAS:Producto controlado<p>Applications Labelled Oxazepam. Anxiolytic; muscle relaxant (skeletal); anticonvulsant; ligand for the GABAA receptor benzodiazepinemodulatory site.Controlled substance (depressant).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Sisenwine, et al.: Arzneim. Forsch., 22, 682 (1972), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 3, 441 (1974), Greenblatt, D.J., et al.: Clin. Pharmacokinet., 6, 89 (1981),<br></p>Fórmula:C152H5H6ClN2O2Forma y color:Off-WhitePeso molecular:291.74(R)-Rivastigmine
CAS:Producto controlado<p>Impurity Rivastigmine EP Impurity D<br>Applications (R)-Rivastigmine (Rivastigmine EP Impurity D) is a carbamate inhibitor of acetylcholinesterase used as a treatment of Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lucangioli, S. E., et al.: J. Chromatogr. A, 1081, 31-35 (2005); Bar-On, P., et al.: Biochem., 41, 3555-3564 (2002);<br></p>Fórmula:C14H22N2O2·C4H6O6Forma y color:NeatPeso molecular:400.42Imidacloprid-d4
CAS:Producto controlado<p>Applications Imidacloprid-d4 is labelled Imidacloprid (I274990) which is a neonicotinoid, the active ingredient in certain neuro-active insecticides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:C92H4H6ClN5O2Forma y color:WhitePeso molecular:259.69Tert-Butyl 6-(benzyloxy)-4-fluoro-1H-indazole-1-carboxylate
CAS:Pureza:95.0%Peso molecular:342.3699951171875Methyl 5-((4-bromo-2-fluorophenyl)amino)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate
Pureza:95%Peso molecular:396.1919860839844SODIUM 5-METHYL-1,3-OXAZOLE-2-CARBOXYLATE
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:149.08099365234375TRAM-34
CAS:Producto controlado<p>Applications TRAM-34 blocks intermediate conductance calcium-activated potassium channel IKCa1 with a Kd of 20nM and exhibits exquisite selectivity for the channel. Clotrimazole impurity.<br>References Wulff, H., et al.: J. of Biological Chemistry, 276, 34, 32040 (2001)<br></p>Fórmula:C22H17ClN2Forma y color:NeatPeso molecular:344.84Thiabendazole-d4 (Major)
CAS:Producto controladoFórmula:C10D4H3N3SForma y color:Off WhitePeso molecular:205.274,4'-Dicyanobenzophenone
CAS:<p>Applications Letrozole intermediate.<br>References Gomez, R., et al.: J. Mat. Chem., 17, 4274 (2007),<br></p>Fórmula:C15H8N2OForma y color:Light BrownPeso molecular:232.24Ref: 10-F538114
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar3-(4,5-Diphenyl-1,3-oxazol-2-yl)propanoic acid
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:293.32199096679691-(2-Trifluoromethylphenyl)imidazole
CAS:Fórmula:C10H7F3N2Pureza:98.0%Forma y color:SolidPeso molecular:212.175N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide
CAS:<p>Applications N-(2-Hydroxyethyl)-5-methyl-1,2,4-oxadiazole-3-carboxamide is a photolysis product of Metronidazole (M338880), an antibiotic.<br>References Moore, Douglas E., et al.: Radiation Phy. and Chem., 36(4), 547-50 (1990)<br></p>Fórmula:C6H9N3O3Forma y color:NeatPeso molecular:171.1542-(benzylthio)-1H-benzimidazole
CAS:Pureza:95.0%Forma y color:Solid, White powderPeso molecular:240.32000732421875Omeprazole-d3 Sulfide
CAS:Producto controladoFórmula:C172H3H16N3O2SForma y color:NeatPeso molecular:332.44Methyl 2-(1H-imidazol-1-yl)acetate
CAS:Fórmula:C6H8N2O2Pureza:95.0%Forma y color:SolidPeso molecular:140.142N-Ethyl-N-(4-picolyl)atropamide (>85%)
CAS:<p>Stability Light Sensitive<br>Applications N-Ethyl-N-(4-picolyl)atropamide is a major impurity of Tropicamide (T892650), a medication used to dilate the pupil.<br>References Stefanowicz, Zdzislawa, et al.: J. of Pharma. and Biomed. Analy., 49(2), 214-220 (2009)<br></p>Fórmula:C17H18N2OPureza:>85%Forma y color:NeatPeso molecular:266.34Triclabendazole
CAS:Producto controlado<p>Applications An anthelmintic (fasciola).<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Fórmula:C14H9Cl3N2OSForma y color:NeatPeso molecular:359.66Mebendazole-d8
CAS:Producto controlado<p>Applications Labelled Mebendazole (M200500). Anthelmintic (Nematodes).<br>References Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 16, 291 (1987)<br></p>Fórmula:C162H3H10N3O3Forma y color:NeatPeso molecular:298.312-Mercapto-4,5,6,7-d4-benzimidazole
CAS:Producto controladoFórmula:C72H4H2N2SForma y color:NeatPeso molecular:154.23Tebuconazole-d9
CAS:Producto controlado<p>Applications Isotope labelled Tebuconazole (T013000), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Grimalt S. et al.: Anal Bioanal Chem. 2015 Apr;407(11):3083-91 2. Gent, D. et al.: Plant Dis. 2003 May:87(5) p591-5973. Wang, C. et al.: Pest. Biochem. Physiol. 2007 Jan:87(1) p1-8<br></p>Fórmula:C16H13D9ClN3OForma y color:White To Light YellowPeso molecular:316.872-Aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1H-1,4-benzodiazepine
CAS:Producto controlado<p>Applications An Intermediate for the synthesis of Midazolam.<br>References Walser, A., J. Org. Chem., 43, 936 (1978).<br></p>Fórmula:C16H15ClFN3Forma y color:NeatPeso molecular:303.765-(S-Methyl) Albendazole
CAS:<p>Impurity Albendazole EP Impurity F<br>Applications 5-(S-Methyl) Albendazole is a metabolite of Albendazole (A511610). Albendazole EP Impurity F<br>References Gyurik, R.J., et al.: Drug Metab. Dispos., 9, 503 (1981),<br></p>Fórmula:C10H11N3O2SForma y color:NeatPeso molecular:237.283-(1H-Imidazol-4-yl)acrylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:138.126007080078123-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Forma y color:NeatPeso molecular:252.27(3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione
CAS:Producto controlado<p>Applications (3aR,7aS)-rel-Hexahydro-1,3-isobenzofurandione is a reagent used in the synthesis of Pregabalin (P704800), a GABA analogue used as an anticonvulsant. Also used to prepare P2X7 receptor antagonists.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999); Eur. J. Org. Chem., 2013, 4495 (2013); Yang, H. et al.: Chinese. Chem. Lett., 24, 553 (2013);<br></p>Fórmula:C8H10O3Forma y color:NeatPeso molecular:154.16(R)-Rabeprazole Sodium Salt
CAS:Producto controlado<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Fórmula:C18H20N3NaO3SForma y color:NeatPeso molecular:381.42(1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide
CAS:Producto controlado<p>Impurity Tiotropium bromide EP impurity C<br>Applications (1R,3S,5S)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium Bromide is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Fórmula:C19H22NO3S2·BrForma y color:NeatPeso molecular:456.42Ravuconazole-d4
CAS:Producto controlado<p>Applications Ergosterol biosynthesis inhibitor. Antifungal.<br>References Fung-Tomc., J.C., et al.: Antimicrob. Agents Chemother., 42, 313 (1988), Tsuruoka, A., et al.: Chem. Pharm. Bull., 46, 623 (1998), Gupta, A.K., et al.: J. Eur. Acad. Dermatol. Venereol., 19, 437 (2005),<br></p>Fórmula:C22H13D4F2N5OSForma y color:NeatPeso molecular:441.49Oxybutynin Chloride
CAS:Producto controlado<p>Applications An inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999), Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Fórmula:C22H31NO3·ClHForma y color:White To Off-WhitePeso molecular:393.95(R)-Modafinil Carboxylate Methyl Ester
CAS:Producto controladoFórmula:C16H16O3SForma y color:NeatPeso molecular:288.365-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O4SForma y color:NeatPeso molecular:361.423-(2,3-Dichlorobenzamido) Lamotrigine
CAS:<p>Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D<br>Stability Light Sensitive<br>Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Fórmula:C16H9Cl4N5OForma y color:NeatPeso molecular:429.094-chloro-N-[3-(1H-imidazol-1-yl)propyl]-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:292.7900085449219Parbendazole
CAS:Producto controlado<p>Applications Parbendazole is a benzimidazole carbamate and a potent inhibitor of microtubule assembly and functions.<br>References Lahon, L.C.. et al.: Ind. J. Pharmacol., 26, 235 (1994); Havercroft, J.C., et al.: J. Cell. Sci., 49, 195 (1981);<br></p>Fórmula:C13H17N3O2Forma y color:NeatPeso molecular:247.29NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Fórmula:C10H15NOForma y color:WhitePeso molecular:165.23Rivastigmine N-Oxide (Technical Grade)
CAS:Producto controlado<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Fórmula:C14H22N2O3Forma y color:Light Yellow LiquidPeso molecular:266.34Temazepam-13C,d3
CAS:Producto controlado<p>Applications Temazepam-13C,d3 is labelled Temazepam (T017200) which is a pharmacologically active metabolite of Diazepam. It is used as a sedative and hypnotic drug.<br>References Sarteschi, P., et al.: Arzneim.-Forsch., 22, 93 (1972), Schwandt, H.J., et al.: Xenobiotica, 4, 733 (1974), Curry, S.H., et al.: Br. J. Pharmacol., 57, 427 (1976), Heel, R.C., et al.: Drugs, 21, 321 (1981),<br></p>Fórmula:C1513CH10D3ClN2O2Forma y color:NeatPeso molecular:304.75Keto Itraconazole
CAS:Producto controladoFórmula:C35H36Cl2N8O5Forma y color:NeatPeso molecular:719.629-Hydroxy Propantheline Bromide
CAS:<p>Applications A major impurity of the antimuscarinic agent Propantheline Bromide (P760900).<br>References Ford, B.L. et al.: J. Assoc. Off. Anal. Chem., 67, 934 (1984); Mourier, P.A.: Analusis, 17, 67 (1989);<br></p>Fórmula:C23H30NO4·BrForma y color:NeatPeso molecular:464.39Lansoprazole N-oxide
CAS:<p>Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).</p>Fórmula:C16H14F3N3O3SPureza:Min. 95%Forma y color:White PowderPeso molecular:385.36 g/mol10,11-Dihydroxy-d10 Carbamazepine
Producto controlado<p>10,11-Dihydroxy-d10 Carbamazepine is a drug product that is used as an analytical reference standard. It is natural and synthetic impurity in the API (active pharmaceutical ingredient) Carbamazepine. The CAS number for 10,11-Dihydroxy-d10 Carbamazepine is 513-81-5. This compound has been synthesized by custom synthesis and is an impurity standard for HPLC analysis of carbamazepine. 10,11-Dihydroxy-d10 Carbamazepine is also a research and development chemical for the drug development industry. It has been classified as a niche chemical due to its high purity and pharmacopoeia grade.</p>Pureza:Min. 95%2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Fórmula:C18H21N3O2SPureza:Min. 95%Forma y color:White PowderPeso molecular:343.44 g/mol1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine
CAS:<p>1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.</p>Fórmula:C24H27NO3Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:377.48 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS:<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>Fórmula:C16H16ClN3O2SPureza:Min. 95%Forma y color:PowderPeso molecular:349.84 g/mol(1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl-2'-hydroxy-2',2'-di(thiophen-2''-yl)acetate
CAS:<p>Tanshinone IIA is an enantioselective hydroxamic acid that inhibits matrix metalloproteinase. It is a structural analogue of the hydroxamic acid Tanshinone I and has been shown to inhibit aggrecanase, which is an enzyme that hydrolyzes the glycosaminoglycan aggrecan. It also has anti-cancer effects due to its inhibition of cell proliferation in cancer cells. Tanshinone IIA can be used as a chiral synthon for polymerase chain reactions (PCR) because it contains a stereogenic centre in its structure.</p>Fórmula:C18H19NO3S2Pureza:Min. 95%Forma y color:PowderPeso molecular:361.48 g/molAlbendazole sulfoxide
CAS:<p>Albendazole sulfoxide is a sulfoxide of albendazole. The molecular docking analysis of the two molecules showed that the sulfoxide group is located in the same position as the hydroxyl group on albendazole. It has been shown that this replacement of hydroxyl with a sulfoxide group increases the solubility and stability of albendazole, which may be due to hydrogen bonding interactions between these groups. Albendazole sulfoxide has been shown to be an effective treatment for infections caused by parasites such as helminths. However, it should not be used in combination with drugs that are metabolized by cytochrome P450 enzymes because it can inhibit their activity.</p>Fórmula:C12H15N3O3SPureza:Min. 97 Area-%Forma y color:White PowderPeso molecular:281.33 g/molPantoprazole sulfide N-oxide
CAS:<p>Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.</p>Fórmula:C16H15F2N3O4SPureza:Min. 95%Forma y color:Off-White To Yellow SolidPeso molecular:383.37 g/mol(R)-5-Hydroxymethyl tolterodine
CAS:<p>(R)-5-Hydroxymethyl tolterodine is a prodrug that is metabolized by cytochrome P450 3A4 (CYP3A4) in the liver to its active form, tolterodine. This drug can be used as an alternative for gabapentin in the treatment of detrusor muscle overactivity associated with neurogenic bladder dysfunction. The pharmacokinetic properties of (R)-5-hydroxymethyl tolterodine are similar to those of gabapentin, including the elimination half-life and volume of distribution. However, unlike gabapentin, which has been shown to increase the glomerular filtration rate (GFR) and renal blood flow, there is no evidence that this drug has any effect on GFR or renal blood flow. There is also no evidence that (R)-5-hydroxymethyl tolterodine causes any symptoms that may be attributed to</p>Fórmula:C22H31NO2Pureza:Min. 98 Area-%Forma y color:Off-White PowderPeso molecular:341.49 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]thio]-1H-benzimidazole
CAS:<p>Omeprazole is a drug that belongs to the class of benzimidazole compounds. It is an inhibitor of gastric acid secretion in the stomach, reducing the production of hydrochloric acid and pepsin. Omeprazole has been shown to have greater chemical stability than other proton pump inhibitors (PPIs), with a higher solubility in water and a longer shelf life. Omeprazole also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Omeprazole also exhibits pharmacokinetic properties that are different from other PPIs. Omeprazole is rapidly absorbed following oral administration and has a high bioavailability, which can be attributed to its hydroxyl group. This hydroxyl group allows for esomeprazole (a prodrug) to be formed by hydrolysis in the gut or liver, increasing omeprazole's absorption and bioavailability.</p>Fórmula:C17H19N3O2SPureza:Min. 95%Forma y color:PowderPeso molecular:329.42 g/mol4-Isobutyl-2-pyrrolidinone
CAS:<p>4-Isobutyl-2-pyrrolidinone is a colorless liquid that belongs to the category of phosphites. It has a high boiling point, which makes it suitable for use in organic solvents and as a heat transfer agent. The thermodynamic properties of 4-Isobutyl-2-pyrrolidinone have been evaluated using the protonation theory. It can be protonated at either the nitrogen or the methyl group, and both forms are present in solution. This means that 4-Isobutyl-2-pyrrolidinone is acidic and can react with other compounds to form salts called lactams. There are two isomers of this compound: cis and trans. Both isomers exist in equilibrium; however, the cis isomer predominates at room temperature. The most common impurities of 4-Isobutyl-2-pyrrolidinone are dehydration products formed during synthesis or</p>Fórmula:C8H15NOPureza:Min. 95%Forma y color:White PowderPeso molecular:141.21 g/mol2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
CAS:<p>2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].</p>Fórmula:C15H15N3OS2Pureza:Min. 95%Peso molecular:317.43 g/molRabeprazole Impurity 2
CAS:<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Fórmula:C18H19N3O4Pureza:Min. 95%Peso molecular:341.36 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.</p>Fórmula:C16H17N3O2SPureza:Min. 95%Forma y color:PowderPeso molecular:315.39 g/mol3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one
CAS:<p>3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one is a triazine derivative that is used as an analytical reagent and intermediate. It has been used as a wastewater analysis method to measure the concentration of carbamazepine. 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one has also been shown to be useful in developing analytical methods for clinical trials. 3DCTKP has also been used to test the matrix effect of carbamazepine by analyzing it in different matrices such as water and human plasma.</p>Fórmula:C9H6Cl2N4OPureza:Min. 95 Area-%Forma y color:PowderPeso molecular:257.08 g/molCarbendazim
CAS:<p>Carbendazim is a fungicide that inhibits the growth of fungi and bacteria. It has been shown to be potent inducers of polymerase chain reaction (PCR) amplification, with a rate constant of 0.0103 per minute. Carbendazim also has a significant effect on electrochemical impedance spectroscopy (EIS). The EIS analysis was used to compare carbendazim-treated cells with untreated cells, which showed that carbendazim causes an increase in the resistance across the cell membrane. This research suggests that carbendazim may be genotoxic, as it increased the amount of DNA damage observed in wild-type strains and altered the optical properties of DNA. Carbendazim is also an effective inhibitor of nitrite ion oxidation and colloidal gold deposition, which has led to its use as a water vapor control agent for plants.</p>Fórmula:C9H9N3O2Pureza:Min. 95%Forma y color:PowderPeso molecular:191.19 g/molOmeprazole impurity F and G
CAS:<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Fórmula:C16H13N3O2SPureza:Min. 95%Forma y color:Red PowderPeso molecular:311.36 g/mol2,3-Dichlorobenzoic acid
CAS:<p>2,3-Dichlorobenzoic acid is an organic compound that belongs to the class of carboxylates. It is used as a drug substance in the treatment of mycobacterial infections. 2,3-Dichlorobenzoic acid has been shown to have antimicrobial activity against Mycobacterium tuberculosis and other mycobacteria. The sensitivity index for this compound was determined using a chromatographic method with human erythrocytes as the test organism. 2,3-Dichlorobenzoic acid displays its antibacterial activity by inhibiting protein synthesis and cell division. This drug also forms crystalline solids that are soluble in organic solvents such as chloroform or benzene.</p>Fórmula:C7H4Cl2O2Pureza:Min. 95%Forma y color:PowderPeso molecular:191.01 g/mol4-Desmethoxy omeprazole sulfide
CAS:<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Fórmula:C16H17N3OSPureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:299.39 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M</p>Fórmula:C17H19N3O4SPureza:Min. 95%Forma y color:White Off-White PowderPeso molecular:361.42 g/mol6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
CAS:<p>6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is a metabolite that can be found in the urine and blood of humans. It has been shown to have cytotoxic effects on human lymphocytes and erythrocytes. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is used as an impurity standard for HPLC analysis and as a reference compound for pharmacopoeia. This chemical is also used in the synthesis of some drugs. 6-(2,4-Dichlorophenyl)-1,2,4-triazine-3,5-diamine is not listed in any pharmacopoeia or natural product database.</p>Fórmula:C9H7Cl2N5Pureza:Min. 95%Forma y color:White PowderPeso molecular:256.09 g/molDi-2-thienylmethanone
CAS:<p>Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.</p>Fórmula:C9H6OS2Pureza:Min. 95%Forma y color:White PowderPeso molecular:194.28 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS:<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Fórmula:C17H17F2N3O4SPureza:Min. 95%Forma y color:Off-white to yellow powder.Peso molecular:397.4 g/molPantoprazole N-oxide sodium
CAS:<p>Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.</p>Fórmula:C16H15F2N3O5S·NaPureza:Min. 95%Forma y color:PowderPeso molecular:422.36 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS:<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Fórmula:C17H19N3O5SPureza:Min. 95%Forma y color:PowderPeso molecular:377.42 g/molDihydroxy diketo atorvastatin impurity
CAS:<p>Dihydroxy diketo atorvastatin impurity is a synthetic impurity that is generated by the metabolism of atorvastatin. This drug product is an analytical standard for the determination of purity, and can also be used to develop high purity drugs.</p>Fórmula:C26H24FNO5Pureza:Min. 95%Peso molecular:449.47 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Fórmula:C15H15NPureza:Min. 95%Forma y color:White PowderPeso molecular:209.29 g/mol
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