Derivados de Benzimidazol e Imidazol
El benzimidazol es un compuesto que consta de un anillo bencénico fusionado a un anillo imidazol, una estructura de cinco miembros que contiene dos átomos de nitrógeno. Los derivados de benzimidazol, como el albendazol, son conocidos por su actividad antiparasitaria y antifúngica, utilizados en el tratamiento de infecciones parasitarias y en algunas enfermedades parasitarias en animales y humanos. El imidazol, por su parte, es una estructura de cinco miembros con dos átomos de nitrógeno, que se encuentra en diversos compuestos biológicamente activos. Los derivados de imidazol, como el metronidazol, tienen propiedades antimicrobianas y antiparasitarias. Estos compuestos también se usan en la industria farmacéutica para tratar infecciones bacterianas, enfermedades parasitarias y algunas infecciones fúngicas, además de tener aplicaciones en la química orgánica como catalizadores.
En CymitQuimica ofrecemos benzimidazoles e imidazoles de alta pureza para investigación en química medicinal, farmacología y biotecnología.
Se han encontrado 10375 productos de "Derivados de Benzimidazol e Imidazol"
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(S)-Modafinil-d10
CAS:Producto controlado<p>Applications Labelled (S)-Modafinil. Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999), Purnell, M., et al.: J. Sleep Res., 11, 219 (2002), Dinges, D., et al.: Curr. Med. Res. Opin., 22, 159 (2006)<br></p>Fórmula:C15D10H5NO2SForma y color:NeatPeso molecular:283.41Varenicline-d2,15N2 Dihydrochloride
CAS:Producto controlado<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Fórmula:C13H13D2Cl2N15N2Forma y color:Light Beige SolidPeso molecular:288.18Lurasidone Opened Imide (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Lurasidone Opened Imide is an impurity in the synthesis of Lurasidone (L474920) which is antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008);<br></p>Fórmula:C28H38N4O3SForma y color:NeatPeso molecular:510.695,6-Dimethoxyindane-1,3-dione
CAS:Producto controladoFórmula:C11H10O4Forma y color:NeatPeso molecular:206.199-Acridinecarboxylic acid
CAS:Producto controlado<p>Applications 9-Acridinecarboxylic acid is used in the synthesis of short DNA-binding peptides.<br></p>Fórmula:C14H9NO2Forma y color:YellowPeso molecular:223.23Butyl Itraconazole
CAS:Producto controladoFórmula:C35H38Cl2N8O4Forma y color:NeatPeso molecular:705.63Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Producto controlado<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Fórmula:C34H36Cl2N8O5Forma y color:NeatPeso molecular:707.61Nitroguanidine (Wetted with water >20%)
CAS:Producto controlado<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:CH4N4O2Forma y color:White To Off-WhitePeso molecular:104.07N-Nitroso Aryl Lurasidone
CAS:Producto controladoFórmula:C11H12N4OSForma y color:NeatPeso molecular:248.31(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS:Producto controladoFórmula:C28H30N2O2Forma y color:NeatPeso molecular:426.55Metopimazine
CAS:<p>Applications Metopimazine (MPZ) is used to prevent emesis during chemotherapies. Antiemetic.<br>References Catz, P., et al.: Int. J. Pharm., 58, 93 (1990), Sato, K., et al.: J. Pharm. Sci., 80, 104 (1991), Herrstedt, J., et al.: Cancer Chemother. Pharmacol., 33, 53 (1996), Sigsgaard, T., et al.: J. Clin. Onc., 19, 2091 (2001),<br></p>Fórmula:C22H27N3O3S2Forma y color:Off White SolidPeso molecular:445.60Isopropyl Itraconazole
CAS:Producto controladoFórmula:C34H36Cl2N8O4Forma y color:NeatPeso molecular:691.61Varenicline Carbamoyl β-D-Glucuronide
CAS:Producto controlado<p>Applications A metabolite of Varenicline.<br>References Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005), Obach, R., et al.: Drug Metab. Dispos., 33, 262 (2005),<br></p>Fórmula:C20H21N3O8Forma y color:NeatPeso molecular:431.4rac N-Demethyl Promethazine-d3 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Promethazine (P757000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keipert, S., et al.: Pharmazie, 31, 296 (1976),<br></p>Fórmula:C16H16D3ClN2SForma y color:NeatPeso molecular:309.871-Chloro-2-(dichlorophenylmethyl)benzene
CAS:Producto controlado<p>Applications 1-Chloro-2-(dichlorophenylmethyl)benzene is an intermediate used in the preparation of 2-chlorotrityl chloride resins. 1-Chloro-2-(dichlorophenylmethyl)benzene is an impurity of the antifungal agent Clotrimazole (C587400).<br>References Li, P. et al.: Guoch. Gong. Xue., 9, 558 (2009);<br></p>Fórmula:C13H9Cl3Forma y color:Light YellowPeso molecular:271.57Isometronidazole-D4
CAS:Producto controlado<p>Applications Isometronidazole-D4 is a labelled analogue of Isometronidazole (I821342). Isometronidazole is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Fórmula:C6D4H5N3O3Forma y color:NeatPeso molecular:175.18Propyl Itraconazole
CAS:Producto controladoFórmula:C34H36Cl2N8O4Forma y color:NeatPeso molecular:691.614'-Desmethoxy Omeprazole
CAS:Producto controlado<p>Applications 4'-Desmethoxy Omeprazole is one of two impurities in the synthesis of Esomeprazole, an anti-ulcerative drug for treatment of acid-related diseases.<br>References Liu, X., et al.: Lat. Am. J. Pharm., 34, 1265-1268 (2015);<br></p>Fórmula:C16H17N3O2SForma y color:NeatPeso molecular:315.393-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Producto controlado<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Fórmula:C8H16BrNOForma y color:NeatPeso molecular:222.122,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Producto controladoFórmula:C16H12Cl4N2OS·ClHForma y color:NeatPeso molecular:458.62
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