Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8896 productos de "Derivados de Purinas y Pirimidinas"
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2-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Fórmula:C10H13N5O4S·x(H2O)Forma y color:Light Yellow PowderPeso molecular:299.316-Mercaptopurine Monohydrate
CAS:Producto controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Fórmula:C5H4N4S·H2OForma y color:YellowPeso molecular:170.19N-Desacetyl 5-Azido Oseltamivir
CAS:Producto controlado<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),<br></p>Fórmula:C14H24N4O3Forma y color:NeatPeso molecular:296.37N4-(3-Aminophenyl)-5-fluoro-N2-(4-(2-methoxyethoxy)phenyl)pyrimidine-2,4-diamine
CAS:Pureza:98.0%Peso molecular:369.3999938964844Nicotinamide-d4 N-Oxide (d4 Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Nicotinamide.<br>References Musfeld, C., et al.: J. Pharm. Biomed. Anal., 24, 391 (2001), Sakakibara, Y., et al.: Brain Res., 931, 68 (2002), Zielonka, J., et al.: Chem. Res. Toxicol., 19, 668 (2006), Wieczorkowska, M., et al.: Pharmacol. Rep., 59, 216 (2007),<br></p>Fórmula:C6H2D4N2O2Forma y color:NeatPeso molecular:142.153-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Impurity Allopurinol EP Impurity E / Allopurinol USP Related Compound E<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975)<br></p>Fórmula:C7H9N3O3Forma y color:WhitePeso molecular:183.16Urea-urethane Compound (~85%)
CAS:Producto controlado<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Fórmula:C42H36N6O8SPureza:~80%Forma y color:NeatPeso molecular:784.84Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor, used for treatment of hyperuricemia and chronic gout.<br>References Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005);<br></p>Fórmula:C18H21NO4SForma y color:NeatPeso molecular:347.43N-Butyldeoxynojirimycin Hydrochloride-d9
CAS:Producto controlado<p>Applications N-Butyldeoxynojirimycin Hydrochloride-d9 is labelled N-Butyldeoxynojirimycin Hydrochloride (B691000) which is an inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity.<br>References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),<br></p>Fórmula:C10H13D9ClNO4Forma y color:NeatPeso molecular:264.791-(5-Bromopyrimidin-2-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS:Pureza:95.0%Peso molecular:291.1080017089844Ioxitalamic Acid-d4
CAS:Producto controlado<p>Applications A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system.<br>References Frocrain, L., et al.: Radiology, 170, 531 (1989), van Waes, P.F., et al.: Eur. J. Radiology, 9,179 (1989)<br></p>Fórmula:C12H7D4I3N2O5Forma y color:White To Light BrownPeso molecular:647.966-Mercaptopurine-13C2,15N (major)
CAS:Producto controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naguib, F., et al.: Biochem. Pharmacol., 50, 1685 (1995), Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004).<br></p>Fórmula:C313C2H4N315NSForma y color:NeatPeso molecular:155.16Mono-POC Tenofovir
CAS:<p>Stability Hygroscopic<br>Applications An impurity of Tenofovir Disoproxil (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. It is used as an anti-HIV agent and an antiviral.<br>References Gan, L., et al.: Drug Metab. Dispos., 24, 344 (1996), Annaert, P., et al.: Pharm. Res., 14, 492 (1997), Naesens, L., et al.: Antimicrob. Agents Chemother., 42, 1568 (1998), Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Fórmula:C14H22N5O7PForma y color:White To Light BeigePeso molecular:403.336-Methyl Nicotinic Acid
CAS:Producto controlado<p>Applications A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.<br>References Ensign, J., et al.: Biol. Chem., 239, 2285 (1964), Houghton, C., et al.: Biochem. J., 130, 879 (1972),<br></p>Fórmula:C7H7NO2Forma y color:NeatPeso molecular:137.14N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
CAS:Producto controlado<p>Applications N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);<br></p>Fórmula:C15H25N6O5PPureza:>85%Forma y color:NeatPeso molecular:400.37Sumatriptan
CAS:Producto controlado<p>Applications Sumatriptan is a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)<br></p>Fórmula:C14H21N3O2SForma y color:White To Light YellowPeso molecular:295.40N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide
CAS:Peso molecular:396.47000122070311-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
CAS:Pureza:95.0%Peso molecular:396.45098876953125
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