Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8902 productos de "Derivados de Purinas y Pirimidinas"
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Rizatriptan EP Impurity H N10-d6 (Rizatriptan N10-Oxide-d6)
CAS:Fórmula:C15H13D6N5OPeso molecular:291.39Pentostatin
CAS:<p>Pentostatin (CI-825) is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM).</p>Fórmula:C11H16N4O4Pureza:99.57% - 99.89%Forma y color:White CrystalsPeso molecular:268.27O6-Benzylguanine
CAS:<p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>Fórmula:C12H11N5OPureza:98.9%Forma y color:Solid CrystallinePeso molecular:241.256-Amino-5-(ethylamino)-1-methyl-2,4(1H,3H)-Pyrimidinedione
CAS:Fórmula:C7H12N4O2Peso molecular:184.20Almotriptan Malate
CAS:<p>Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.</p>Fórmula:C17H25N3O2S·C4H6O5Pureza:99.95%Forma y color:Pale Yellow SolidPeso molecular:469.55Lorlatinib
CAS:<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Fórmula:C21H19FN6O2Pureza:99.77% - 99.95%Forma y color:SolidPeso molecular:406.41Regadenoson
CAS:<p>Regadenoson (CVT-3146) is a selective A2A receptor agonist that increases coronary blood flow with a longer half-life than adenosine.</p>Fórmula:C15H18N8O5Pureza:99.57% - 99.81%Forma y color:Off-White SolidPeso molecular:390.35Methopterine (>90%)
CAS:Producto controlado<p>Impurity Methotrexate EP Impurity C; Methotrexate USP Related Compound C<br>Applications Methopterine (Methotrexate EP Impurity C) is a Folic acid (F680300) analogue. Methopterine is effective in the treatment of ectopic pregnancy. Methotrexate USP Related Compound C<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McNamara, P., et al.: Drug Metab. Dispos., 20, 302 (1992), Soldin, O., et al.: Ther. Drug Monit., 24, 1 (2002), Nicoli, S., et al.: J. Pharm. Biomed. Anal., 41, 994 (2006),<br></p>Fórmula:C20H21N7O6Pureza:>90%Forma y color:NeatPeso molecular:455.42(S)-Tenofovir
CAS:Producto controlado<p>Applications (S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts.<br>References Balzarini, J. et al: Biochem. Biophys. Res. Comm., 219, 337 (1996); Balzarini, J. et al.: Antimicrob. Agents. Ch., 37, 332 (1993); Thormar, H. et al.: Antimicorb. Agents. Ch., 37, 2540 (1993)<br></p>Fórmula:C9H14N5O4PForma y color:NeatPeso molecular:287.21Iopamidol
CAS:<p>Applications Nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).<br>References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),<br></p>Fórmula:C17H22I3N3O8Forma y color:WhitePeso molecular:777.09Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
CAS:<p>Applications Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C18H20N2O3SForma y color:NeatPeso molecular:344.43S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride
CAS:Producto controlado<p>Applications S(+)-N-(2-(2-Thienyl)ethyl)-2-chlorophenyl Glycine Methyl Ester Hydrochloride is an impurity from Clopidogrel (C587250) which acts as an anti-platelet agent.<br>References Zhu, Y. et al.: ACS. Med. Chem. Lett., 4, 349 (2013); Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Fórmula:C15H16ClNO2S·ClHForma y color:NeatPeso molecular:346.27N-Nitroso Desmethyl Rizatriptan
Producto controladoFórmula:C14H16N6OForma y color:NeatPeso molecular:284.316(E/Z)-3-[(2-Cyano-3-ethoxy-3-oxo-1-propenyl)amino]-1H-Pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Applications Impurity of Allopurinol (A547300), an xanthine oxidase inhibitor used in treatment of hyperuricemia and chronic gout. Antiurolithic.<br>References Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978), Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005), Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005),<br></p>Fórmula:C12H14N4O4Forma y color:NeatPeso molecular:278.276-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Fórmula:C18H19N3O2Forma y color:Off-White To Light BrownPeso molecular:309.362Methotrexate Heptaglutamate Trifluoroacetate
CAS:Producto controladoFórmula:C50H64N14O23xC2HF3O2Forma y color:NeatPeso molecular:1229.124-([1,1'-Biphenyl]-4-yl)-6-chloro-2-phenylpyrimidine
CAS:Pureza:95.0%Peso molecular:342.8299865722656Ondansetron
CAS:Producto controlado<p>Applications Ondansetron is a specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Fórmula:C18H19N3OForma y color:White To Light BeigePeso molecular:293.36N10-Methyl Pteroic Acid
CAS:<p>Impurity Methotrexate EP Impurity D<br>Applications N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D.<br>References Cramer, S., et al.: Cancer Res. 1984, 44, 1843 (1984), Hendel, J., et al.: Eur. J. Clin. Pharmacol., 26, 103 (1984),<br></p>Fórmula:C15H14N6O3Forma y color:Orange To Dark RedPeso molecular:326.314-(furan-2-yl)-6-[4-(propan-2-yl)phenyl]pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:279.3429870605469Tenofovir Monohydrate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Fórmula:C9H14N5O4P·H2OForma y color:NeatPeso molecular:305.23Xanthine-13C15N2
CAS:Producto controlado<p>Applications Isotope labelled analog of Xanthine (X499950), a substance that can be found in animal organs, yeast, patatoes, coffee beans, tea. Xanthine can be used to relax and widen certain breathing passages of the lungs. It is also found that a large number of derivatives that exhibits adenoside receptor antagonist properties.<br>References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)<br></p>Fórmula:C413CH4N215N2O2Forma y color:Light Yellow To Light BeigePeso molecular:155.091-Bromo-3-methyladamantane
CAS:Producto controladoFórmula:C11H17BrForma y color:NeatPeso molecular:229.16Paraxanthine-d3
CAS:Producto controlado<p>Applications Paraxanthine-d3, is the labeled analogue of Paraxanthine (P192500), an adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Fórmula:C72H3H5N4O2Forma y color:NeatPeso molecular:183.182,2,2-Trichloro-acetic Acid
CAS:<p>Applications 2,2,2-Trichloro-acetic Acid is an acetic acid analogue used for the precipitation of macromolecules including proteins, DNA and RNA as well as for cosmetic treatments.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wiley D. et al.: Clin. Infect. Dis., 35m S210 (2002);<br></p>Fórmula:C2HCl3O2Forma y color:Colourless To Off-WhitePeso molecular:163.391-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride
Producto controlado<p>Impurity Naratriptan pyridinium Impurity<br>Stability Hygroscopic<br>Applications Naratriptan (N378730) impurity.<br></p>Fórmula:C17H20ClN3O2SForma y color:NeatPeso molecular:365.884-Hydroxy-3-nitrophenylacetic Acid
CAS:Producto controlado<p>Applications A metabolite of Nitrotyrosine (N597000), which is excreted in the urine.<br>References van der Vliet, A., et al.: J. Biol. Chem., 272, 7617 (1997), Tabrizi-Fard, M., et al.: Drug Metab. Dispos., 27, 429 (1999), Souza, J., et al.: Arch. Biochem. Biophys., 380, 360 (2000),<br></p>Fórmula:C8H7NO5Forma y color:NeatPeso molecular:197.14Ethyl 3-Amino-4-pyrazolecarboxylate
CAS:Producto controladoFórmula:C6H9N3O2Forma y color:White To BeigePeso molecular:155.15Caffeine-d3 (1-methyl-d3)
CAS:Producto controlado<p>Applications Caffeine-d3 (1-methyl-d3) (CAS# 26351-03-1) is a useful isotopically labeled research compound.<br></p>Fórmula:C8H7D3N4O2Forma y color:NeatPeso molecular:197.20Methotrexate a-tert-Butyl Ester
CAS:Producto controlado<p>Applications Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Yoshii, T., et al.: J. Am. Chem. Soc., 136, 16635 (2014);<br></p>Fórmula:C24H30N8O5Forma y color:NeatPeso molecular:510.546Methotrexate Diglutamate Trifluoroacetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Methotrexate Diglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C25H29N9O8xC2HF3O2Forma y color:NeatPeso molecular:583.55Methotrexate Dimethyl Ester
CAS:Producto controladoFórmula:C22H26N8O5Forma y color:Light YellowPeso molecular:482.492-Chloro-4-(3-pyridin-4-yl-ureido)benzenesulfonylchloride hydrochloride
CAS:Fórmula:C12H10Cl3N3O3SPureza:98%Forma y color:SolidPeso molecular:382.64Methotrexate (1 mg/mL in Methanol with 0.1N NaOH)
CAS:Fórmula:C20H22N8O5Forma y color:Single SolutionPeso molecular:454.442-Chloro Adenosine
CAS:<p>Applications A selective A1-adenosine receptor agonist. Induces apoptosis.<br>References Evans, et al.: Neurosci. Lett., 83, 287 (1987), Szondy, Z.: Biochem. J., 304, 877 (1994)<br></p>Fórmula:C10H12ClN5O4Forma y color:Off-WhitePeso molecular:301.69Ondansetron Hydrochloride Dihydrate
CAS:Fórmula:C18H19N3O·ClH·2H2OForma y color:Off-WhitePeso molecular:365.85Caffeine-13C
CAS:<p>Applications Caffeine-13C is carbon-13 labeled Caffeine (C080100). Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.A study at Johns Hopkins University indicates that caffeine can improve pattern separation memory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Chem. and Eng. News p.34, Jan. 20, (2014)<br></p>Fórmula:C713CH10N4O2Forma y color:NeatPeso molecular:195.18Isoguanosine Hydrate
CAS:Producto controlado<p>Applications A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5’-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water.<br>References Divakar, K.J., et al.: J. Chem. Soc. Perkin Trans., 1, 771 (1991), Montsch, H.H., et al: Biochemistry, 14, 5593 (1975), Hagen, C.: Biochim. Biophys. Acta., 293, 105 (1973), Huang, M., et al.: J. Med. Chem., 15, 462 (1972)<br></p>Fórmula:C10H13N5O5·H2OForma y color:NeatPeso molecular:301.26Chloromethyl Ethyl Carbonate
CAS:Producto controlado<p>Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.<br>References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);<br></p>Fórmula:C4H7ClO3Forma y color:Colourless OilyPeso molecular:138.552-Isopropyl-pyrimidine-5-carboxylic acid
CAS:Fórmula:C8H10N2O2Pureza:95.0%Forma y color:SolidPeso molecular:166.185-Acetylamino-6-formylamino-3-methyluracil
CAS:Producto controlado<p>Applications Metabolite of Caffeine (C080100).<br>References Grant, D.M., et al.: Clin. Pharm. and Ther., 33, 591 (1983),<br></p>Fórmula:C8H10N4O4Forma y color:Light Yellow SolidPeso molecular:226.19(R)-Methotrexate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H22N8O5Forma y color:Dark YellowPeso molecular:454.54Desisobutyl Febuxostat
CAS:Producto controladoFórmula:C12H8N2O3SForma y color:Light Yellow SolidPeso molecular:260.27Pentostatin
CAS:Producto controlado<p>Applications An adenosine deaminase inhibitor used as an anti-cancer therapeutic drug. Shown to be effective in the treatment of hairy cell leukemia as well as having use in the treatment of other types of cancer such as chronic lymphocytic leukemia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rogler-Brown, T. et al.: Biochem. Pharmacol., 28, 201 (1979); Johnston, J.B. et al.: J. Natl. Canvcer Inst., 80, 765 (1988); Fortune, A.F. et al.: Leuk. and Lymph., 51, 839 (2010); Robak, T. et al.: Drugs, 69, 2415 (2009);<br></p>Fórmula:C11H16N4O4Forma y color:White To Off-WhitePeso molecular:268.273-Descyano-3-((hydroxyimino)methyl) Febuxostat
CAS:Producto controladoFórmula:C16H18N2O4SForma y color:NeatPeso molecular:334.392-Amino-6-(5-methylfuran-2-yl)-5-nitropyrimidin-4-yl 4-methylbenzenesulfonate
CAS:Pureza:97%Peso molecular:390.36999511718751-(3-(2-(Dimethylamino)ethyl-2-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indo-5-yl)-N-methylmethanesulfonamide
Fórmula:C25H33N5O4S2Forma y color:NeatPeso molecular:531.69L-Phenylalanine-13C6
CAS:Producto controlado<p>Applications Labelled analogue of L-Phenylalanine, an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);<br></p>Fórmula:C313C6H11NO2Forma y color:White To Off-WhitePeso molecular:171.15Memantine-Glucose Adduct
Producto controladoFórmula:C18H31NO5Forma y color:NeatPeso molecular:341.4424-(2H-1,3-benzodioxol-5-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:297.32998657226564-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide
CAS:Pureza:95.0%Peso molecular:397.8599853515625Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor, used for treatment of hyperuricemia and chronic gout.<br>References Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005);<br></p>Fórmula:C18H21NO4SForma y color:NeatPeso molecular:347.43(4-N-(Benzhydryloxycarbonyl)cytosine)-1-acetic acid
CAS:Pureza:98.0%Forma y color:SolidPeso molecular:379.372009277343757-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Fórmula:C18H19N3O2Forma y color:NeatPeso molecular:309.362Nicotinamide-d4 N-Oxide (d4 Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Nicotinamide.<br>References Musfeld, C., et al.: J. Pharm. Biomed. Anal., 24, 391 (2001), Sakakibara, Y., et al.: Brain Res., 931, 68 (2002), Zielonka, J., et al.: Chem. Res. Toxicol., 19, 668 (2006), Wieczorkowska, M., et al.: Pharmacol. Rep., 59, 216 (2007),<br></p>Fórmula:C6H2D4N2O2Forma y color:NeatPeso molecular:142.156-Mercaptopurine Monohydrate
CAS:Producto controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Fórmula:C5H4N4S·H2OForma y color:YellowPeso molecular:170.192-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Fórmula:C10H13N5O4S·x(H2O)Forma y color:Light Yellow PowderPeso molecular:299.31N-Desacetyl 5-Azido Oseltamivir
CAS:Producto controlado<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),<br></p>Fórmula:C14H24N4O3Forma y color:NeatPeso molecular:296.374-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide
CAS:Pureza:99.0%Forma y color:SolidPeso molecular:482.82000732421875Ref: 10-F361865
1gA consultar5gA consultar10gA consultar25gA consultar10mgA consultar50mgA consultar100mgA consultar250mgA consultar500mgA consultar(6-Benzhydryloxycarbonylamino-purin-9-yl)-acetic acid
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:403.39801025390625N-[bis(4-methoxyphenyl)methyl]-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide
CAS:Pureza:95%Peso molecular:443.4630126953125N-(3-Chloro-4-(((2-(methylamino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)methyl)phenyl)methanesulfonamide
CAS:Pureza:98.0%Peso molecular:418.89999389648445-Nitro Nicotinic Acid
CAS:Producto controlado<p>Applications An intermediate in the synthesis of nicotinamide with potential anticoccidial activity.<br>References Morisawa, Y. et al.: J. Med. Chem., 20, 129 (1977);<br></p>Fórmula:C6H4N2O4Forma y color:NeatPeso molecular:168.11Memantine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Fórmula:C12H21N·ClHForma y color:White To Off-WhitePeso molecular:215.761-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
CAS:Pureza:95.0%Peso molecular:396.45098876953125Tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
CAS:Pureza:97%Peso molecular:577.71002197265624-(3-Aminophenyl)-2-methylpyrimidine
CAS:Fórmula:C11H11N3Pureza:95.0%Forma y color:SolidPeso molecular:185.234-(3,4-dimethylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:281.38000488281254-(4,6-Dimethoxypyrimidin-2-yl)benzoic acid
CAS:Fórmula:C13H12N2O4Pureza:95.0%Forma y color:SolidPeso molecular:260.249Porphobilinogen
CAS:Producto controlado<p>Applications An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.<br>References Westall, et al.: Nature, 170, 614 (1952), Cookson, R., et al.: Biochem, J., 57, 476 (1954), MacDonald, J., Can. J. Chem., 35, 715 (1957),<br></p>Fórmula:C10H14N2O4Forma y color:NeatPeso molecular:226.234-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester
CAS:Producto controlado<p>Applications Intermediate in the preparation of Pemetrexed.<br></p>Fórmula:C19H17N5O5Forma y color:WhitePeso molecular:395.37Tenofovir Alafenamide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tenofovir Alafenamide is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Fórmula:C21H29N6O5PForma y color:NeatPeso molecular:476.47Theophylline-7-acetic acid
CAS:Fórmula:C9H10N4O4Pureza:98%Forma y color:Solid, White to almost white powderPeso molecular:238.203D-Neopterin-13C5
CAS:<p>Applications Labelled precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees.<br>References Kobashi, I., et al.: Agric. Biol. Chem., 35, 47 (1971), Fukushima, S., et al.: J. Biol. Chem., 247, 4549 (1972),<br></p>Fórmula:C413C5H11N5O4Forma y color:Light Beige To BrownPeso molecular:258.18Methotrexate-d3 Tetraglutamate Trifluoroacetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Methotrexate-d3 Tetraglutamate is the isotope labelled analog of Methotrexate Tetraglutamate (M260730); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C35H40D3N11O14•(C2HF3O2)xForma y color:NeatPeso molecular:844.87-Methyl Xanthine
CAS:Producto controlado<p>Applications Metabolite of Theophylline and Caffeine.<br>References Yu, Ch. et al.: J. Bacteriol. 191, 4624 (2009); Geraets, L. et al.: Biochem. Pharmacol. 72, 902 (2006).<br></p>Fórmula:C6H6N4O2Forma y color:NeatPeso molecular:166.14Methotrexate-Cadaverine-Biotin Conjugate
Producto controlado<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C35H48N12O6SPureza:>85%Forma y color:NeatPeso molecular:764.9Methotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H22N8O5Forma y color:Yellow To Dark YellowPeso molecular:454.441,7-Dimethyluric Acid-d3
CAS:Producto controladoFórmula:C7H5D3N4O3Forma y color:Off-White To Light GreyPeso molecular:199.182-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS:Pureza:98.0%Forma y color:SolidPeso molecular:349.31698608398441-(6-Ethoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-3-ylamine hydrochloride
CAS:Pureza:95.0%Peso molecular:304.8399963378906L-Phenylalanine-d7
CAS:Producto controlado<p>Applications Labelled analogue of L-Phenylalanine, an essential amino acid.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);<br></p>Fórmula:C9H4D7NO2Forma y color:NeatPeso molecular:172.23Pemetrexed Methyl Ester
CAS:Producto controlado<p>Applications Protected Pemetrexed.<br></p>Fórmula:C22H25N5O6Forma y color:NeatPeso molecular:455.4638N-Nitroso Frovatriptan 1
Fórmula:C14H16N4O2Forma y color:Off-White To Light YellowPeso molecular:272.36-Methyl-2-methylsulfanyl-3H-pyrimidin-4-one
CAS:Pureza:98.0%Forma y color:Solid, CrystallinePeso molecular:156.19999694824222-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester
CAS:<p>Applications 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester, can be used for the synthesis of Febuxostat (F229000), an antipodagrics.<br>References Zheng, F., et al.: Zhongguo Yiyao Gongye Zazhi, 40, 726 (2009);<br></p>Fórmula:C14H12N2O3SForma y color:NeatPeso molecular:288.321-(Naphthalen-2-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea
CAS:Pureza:98%Peso molecular:297.3580017089844CAL-101
CAS:Producto controlado<p>Applications CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.<br>References Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);<br></p>Fórmula:C22H18FN7OForma y color:Light BrownPeso molecular:415.402-[4-(3-chlorophenyl)piperazin-1-yl]-6-methyl-3,4-dihydropyrimidin-4-one
CAS:Pureza:98%Peso molecular:304.7799987792969(3R,11bR)-Tetrabenazine
CAS:Producto controladoFórmula:C19H27NO3Forma y color:NeatPeso molecular:317.42N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:277.33099365234375N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide hydrate
CAS:Pureza:98+%Peso molecular:373.3689880371094Pemetrexed Sodium Methyl Ester
Producto controlado<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Fórmula:C21H22N5NaO6Forma y color:NeatPeso molecular:463.419(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone
CAS:Producto controlado<p>Impurity Zolmitriptan USP Related Compound G<br>Applications An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Zolmitriptan USP Related Compound G.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 5, 2789(1995), Ahmed, S., et al.: Drug. Des. Discov., 15, 239 (1998), Brodie, A., et al.: Steroids, 65, 171 (2000),<br></p>Fórmula:C10H12N2O2Forma y color:NeatPeso molecular:192.214-(TERT-BUTYL)-N-(6-(2-HYDROXYETHOXY)-5-(2-METHOXYPHENOXY)-[2,2'-BIPYRIMIDIN]-4-YL)BENZENESULFONAMIDE
CAS:Pureza:95%Peso molecular:551.619995117188Ref: 10-F802473
1gA consultar2gA consultar5gA consultar50mgA consultar100mgA consultar250mgA consultar500mgA consultar5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide
CAS:Producto controlado<p>Applications 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide is a metabolite of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)<br></p>Fórmula:C6H9N5O2Forma y color:Off-WhitePeso molecular:183.174-Hydroxy-3,5-diiodobenzyl Alcohol
CAS:Producto controlado<p>Applications Intermediate in the production of Thyroxine<br></p>Fórmula:C7H6I2O2Forma y color:NeatPeso molecular:375.931,3,7-Trimethyluric Acid-d3
CAS:Producto controlado<p>Stability Store in freezer<br>Applications A caffeine metabolite.<br>References Regal, K.A., et al.: J. of Chromatography B, 708, 75 (1998)<br></p>Fórmula:C82H3H7N4O3Forma y color:NeatPeso molecular:213.217-Methyl Memantine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 7-Methyl Memantine is an impurity of Memantine (HCl salt, M218000) which is used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Fórmula:C13H23N·ClHForma y color:White SolidPeso molecular:229.791,3-Dimethyluric Acid
CAS:Producto controlado<p>Applications 1,3-Dimethyluric Acid, is a metabolite of Caffeine (C080100), that is shown to have some of Its similar effects.<br>References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),<br></p>Fórmula:C7H8N4O3Forma y color:NeatPeso molecular:196.164-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)PYRIMIDIN-2-AMINE
CAS:Pureza:95.0%Peso molecular:290.1239929199219Ref: 10-F531136
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar
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