Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
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Caffeine Citrate
CAS:<p>Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);<br></p>Fórmula:C8H10N4O2·C6H8O7Forma y color:WhitePeso molecular:386.31cis (2,3)-Dihydro Tetrabenazine
CAS:Producto controlado<p>Applications A metabolite of Tetrabenazine in vivo, which is likely the active pharmacological agent. The cis isomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.<br>References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),<br></p>Fórmula:C19H29NO3Forma y color:NeatPeso molecular:319.446-Oxo-(S,S)-Palonosetron (~90%)
CAS:Producto controlado<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Fórmula:C19H22N2O2Pureza:~90%Forma y color:NeatPeso molecular:310.395-[1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]-6,7-dihydrothieno[3,2-c]pyridiniumBromide (~90%)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications One of the unknown impurities generated during the accelerated stability storage of Clopidogrel bisulfate tablets. Clopidogrel impurity.<br>References Gomez, Y., et al.: J. Pharm. Biomed. Anal., 34, 341 (2004), Ksycinska, H., et al.: J. Pharm. Biomed. Anal., 41, 533 (2006),<br></p>Fórmula:C16H15ClNO2S·BrPureza:~90%Forma y color:NeatPeso molecular:400.722-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS:Producto controlado<p>Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.<br></p>Fórmula:C16H18ClN5O7Forma y color:NeatPeso molecular:427.80Methotrexate Hexaglutamate Trifluoroacetate
CAS:<p>Stability Hygroscopic<br>Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C45H57N13O20·x(C2HF3O2)Forma y color:Yellow SolidPeso molecular:1214.031,11b-Dedihydrotetrabenazine
CAS:Producto controlado<p>Applications 1,11b-Dedihydrotetrabenazine is a product of photolytic degradation of Tetrabenazine (T284000) which is a dopamine depleting agent.<br>References Bourezg, Z., et al.: J. Pharmaceut. Biomed., 91, 138 (2014); Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966); Janovic, J., et al.: Ann. Neurol., 11, 41 (1982); Janovic, J., et al.: Neurology, 38, 391 (1988);<br></p>Fórmula:C19H25NO3Forma y color:NeatPeso molecular:315.415-Aminoimidazole-4-carboxamide-13C2,15N Hydrochloride Salt
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Fórmula:C2C2H615NN3O·HClForma y color:BrownPeso molecular:165.556(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole
CAS:Producto controladoFórmula:C14H18N2Forma y color:NeatPeso molecular:214.315-Hydroxymethyl-N,N-dimethyltryptamine
CAS:Producto controlado<p>Applications Degradation product of Sumatriptan Succinate (S810000).<br>References Xu, X. et al.: J. Pharmaceut. Biomed. 367, 26 (2001)<br></p>Fórmula:C13H18N2OForma y color:WhitePeso molecular:218.29Tenofovir Bis(L-alanine Isopropyl Ester) Amide
CAS:Producto controladoFórmula:C21H36N7O6PForma y color:NeatPeso molecular:513.53Methotrexate-d3 Pentaglutamate Trifluoroacetate (>90%)
CAS:Producto controlado<p>Applications Methotrexate-d3 Pentaglutamate is the isotope labelled analog of Methotrexate Pentaglutamate (M260735); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C40H47D3N12O17(C2HF3O2)xForma y color:NeatPeso molecular:973.91Benzofuran-6-carboxylic Acid
CAS:Producto controlado<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Fórmula:C9H6O3Forma y color:NeatPeso molecular:162.14Glycylglycyl-L-tyrosine
CAS:<p>Applications Fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>Fórmula:C13H17N3O5Forma y color:NeatPeso molecular:295.2912Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate
Producto controlado<p>Applications Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate, is an impurity in the synthesis of Febuxostat n-Butyl Isomer (F229035).<br></p>Fórmula:C18H20N2O3SForma y color:NeatPeso molecular:344.43Thiamine Thiocarbamate
CAS:Producto controlado<p>Applications Thiamine (T344185) impurity.<br></p>Fórmula:C14H20N4O3S2Forma y color:NeatPeso molecular:356.46Methotrexate-d3 (Technical Grade) (100ug/mL in Methanol with 1% 0.1N NaOH)
CAS:Producto controladoFórmula:C20H19D3N8O5Forma y color:Single SolutionPeso molecular:457.46(R)-Methotrexate-d3 (Technincal Grade)
CAS:Producto controladoFórmula:C20H19D3N8O5Forma y color:NeatPeso molecular:457.46Tetrabenazine
CAS:Producto controlado<p>Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Fórmula:C19H27NO3Forma y color:NeatPeso molecular:317.421-Bromoethyl Acetate (~90%)
CAS:Producto controlado<p>Applications 1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of antibiotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zakrzewski, J. et al.: Pol. J. Chem. Technol., 8, 83 (2006); Kamachi, H. et al.: J. Antibiot., 41, 1602 (1988);<br></p>Fórmula:C4H7BrO2Pureza:~90%Forma y color:NeatPeso molecular:167.0p-Chlorophenylcyanoguanidine
CAS:Producto controlado<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Fórmula:C8H7ClN4Forma y color:NeatPeso molecular:194.62Tenofovir Dimer Triethylammonium Salt
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications Tenofovir Dimer is a dimer of Tenofovir (T018500). Tenofovir is a reverse transcriptase inhibitor. Used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Fórmula:C30H56N12O7P2Forma y color:NeatPeso molecular:758.79rac-Clopidogrel Hydrogen Sulfate
CAS:Producto controlado<p>Applications rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010); Defreyn, G. et al.: Thromb. Haemo., 65, 186 (1991);<br></p>Fórmula:C16H16ClNO2S·H2O4SForma y color:Off-WhitePeso molecular:419.905-Aminoimidazole-4-carboxamide-15N2 Hydrochloride (>90%)
CAS:Producto controladoFórmula:C4H7ClN215N2OPureza:>90%Forma y color:NeatPeso molecular:164.56[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
CAS:Producto controlado<p>Applications [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C15H18N5O4PForma y color:NeatPeso molecular:363.314-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide
CAS:Producto controlado<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 4-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide is an intermediate in the synthesis of 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) (A609165), which is an antimigraine agent. A Sumatriptan intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H18ClN3O2SForma y color:NeatPeso molecular:303.81(1R,5R,6R)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic Acid Ethyl Ester
CAS:Producto controlado<p>Applications This compound is an isomer of compound (E925685) used in the synthesis of neuraminidase inhibitors.<br>References Jarinrat K. et al.: Bioorg. Med. Chem. Lett., 20, 2152 (2012);<br></p>Fórmula:C14H22O4Forma y color:NeatPeso molecular:254.321-Methyl-1,4-dihydronicotinamide
CAS:Producto controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 1-Methyl-1,4-dihydronicotinamide (cas# 17750-23-1) is a compound useful in organic synthesis.<br></p>Fórmula:C7H10N2OForma y color:NeatPeso molecular:138.172-Hydroxy-N-(pyridin-4-yl)butanamide
CAS:Producto controlado<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>Fórmula:C9H12N2O2Forma y color:NeatPeso molecular:180.2N-(5-Aminopentyl) Methotrexate Amide
CAS:Producto controlado<p>Applications The 5-aminopentyl amide derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Fan, J. et al.: J. Biol. Chem., 266, 14862 (1991);<br></p>Fórmula:C25H34N10O4Forma y color:NeatPeso molecular:538.6D-Alanine Isopropyl Ester Hydrochloride
CAS:Producto controlado<p>Applications D-Alanine Isopropyl Ester Hydrochloride is a chiral reagent used in the synthesis of nucleotide prodrugs such as (PSI-7977) for the treatment of hepatitis C. Also used in the preparation of synthetic sweeteners.<br>References Sofia, M. et al.: J. Med. Chem., 53, 7202 (2010); Mazur, R. et al.: J. Med. Chem., 16, 1284 (1973);<br></p>Fórmula:C6H14ClNO2Pureza:~90%Forma y color:NeatPeso molecular:167.63Methotrexate Tetraglutamate Trifluoroacetate
CAS:Producto controlado<p>Applications Methotrexate Tetraglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C35H43N11O14xC2HF3O2Forma y color:NeatPeso molecular:841.78(S)-Tenofovir
CAS:<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Fórmula:C9H14N5O4PPureza:99.9%Forma y color:SolidPeso molecular:287.214-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C20H27N4O4S2•ClPureza:Min. 95%Peso molecular:487.04 g/molAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Fórmula:C5H4N4NaOPureza:99.93%Forma y color:SolidPeso molecular:159.1Pemetrexed impurity C
CAS:<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Fórmula:C40H40N10O13Pureza:Min. 95%Peso molecular:868.81 g/molMethotrexate-5-monomethyl ester
CAS:<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Fórmula:C21H24N8O5Pureza:Min. 95%Peso molecular:468.47 g/molMercaptopurine impurity standard
CAS:<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>Pureza:Min. 95%2,4-Diamino-7-pteridinemethanol
CAS:<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Fórmula:C7H8N6OPureza:Min. 95%Peso molecular:192.18 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS:<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Fórmula:C14H18I3N3O6Pureza:Min. 95%Peso molecular:705.02 g/molZolmitriptan related compound D
CAS:<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Fórmula:C19H25N3O4Pureza:Min. 95%Peso molecular:359.42 g/molAllopurinol impurity E
CAS:<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Fórmula:C7H9N3O3Pureza:Min. 95%Peso molecular:183.16 g/molMeropenem EP Impurity A
<p>Meropenem EP Impurity A is a synthetic, high purity, drug product that is used as an impurity standard for Meropenem. It has been synthesized from a custom synthesis and is available in both natural and synthetic form. This impurity can be used to investigate the metabolism of Meropenem and to determine its stability in different environments. The HPLC analysis of this impurity is available as a pharmacopoeia standard.</p>Fórmula:C17H27N3O6SPureza:Min. 95%Peso molecular:401.48 g/molLysine-methotrexate
CAS:<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>Fórmula:C21H27N9O3Pureza:Min. 95%Peso molecular:453.5 g/molAllopurinol impurity A
CAS:<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>Pureza:Min. 95%5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS:<p>5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.</p>Fórmula:C16H20I3N3O8Pureza:Min. 95%Peso molecular:763.06 g/mol3,4-Dihydro naratriptan
CAS:<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Fórmula:C17H23N3O2SPureza:Min. 95%Peso molecular:333.45 g/mol1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS:<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Fórmula:C8H9NO2Pureza:Min. 95%Peso molecular:151.16 g/molClopidogrel Impurity A
CAS:<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Fórmula:C15H15Cl2NO2SPureza:Min. 95%Peso molecular:344.26 g/mol
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![(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM326810.webp&w=3840&q=75)
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