Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8901 productos de "Derivados de Purinas y Pirimidinas"
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4-(2-Chloropyrimidin-4-yl)morpholine
CAS:Fórmula:C8H10ClN3OPureza:98%Forma y color:SolidPeso molecular:199.64L-Phenylalanine-d7
CAS:Producto controlado<p>Applications Labelled analogue of L-Phenylalanine, an essential amino acid.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);<br></p>Fórmula:C9H4D7NO2Forma y color:NeatPeso molecular:172.23Pemetrexed Methyl Ester
CAS:Producto controlado<p>Applications Protected Pemetrexed.<br></p>Fórmula:C22H25N5O6Forma y color:NeatPeso molecular:455.4638Urea-13C
CAS:<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986); Aebischer, P., et al.: Nat. Med., 2, 696(1996); Prakash, S., et al.: Biotechnol. Bioeng., 46, 621(1995);<br></p>Fórmula:CH4N2OForma y color:NeatPeso molecular:61.05CAL-101
CAS:Producto controlado<p>Applications CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.<br>References Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);<br></p>Fórmula:C22H18FN7OForma y color:Light BrownPeso molecular:415.40(3R,11bR)-Tetrabenazine
CAS:Producto controladoFórmula:C19H27NO3Forma y color:NeatPeso molecular:317.42Fenclorim
CAS:Producto controlado<p>Applications Herbicide safener.<br>References Lee, H., et al.: Eur. J. Med. Chem., 40, 862 (2005), Wright, S., et al.: Bioorg. Med. Chem. Lett., 17, 5638 (2007), Brazier-Hicks, M., et al.: J. Biol. Chem., 283, 21102 (2008), Vinggaard, A., et al.: Chem. Res. Toxicol., 21, 813 (2008),<br></p>Fórmula:C10H6Cl2N2Forma y color:BeigePeso molecular:225.074-(furan-2-yl)-6-[4-(propan-2-yl)phenyl]pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:279.34298706054691-(1,3-Dioxolan-2-ylmethyl)-N-methyl-4-(methylamino)-1H-imidazole-5-carboxamide
CAS:Producto controladoFórmula:C10H16N4O3Forma y color:NeatPeso molecular:240.26Uric Acid
CAS:<p>Applications Uric Acid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006);<br></p>Fórmula:C5H4N4O3Forma y color:NeatPeso molecular:168.11Febuxostat 2-Butyl Isomer
CAS:Producto controlado<p>Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C16H16N2O3SForma y color:NeatPeso molecular:316.374-(3,4-dimethylphenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:365.4330139160156N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:355.35400390625N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)-3-(trifluoromethyl)pyridine-2-sulfonamide
CAS:Pureza:98%Forma y color:SolidPeso molecular:407.3200073N-(3,4-Dimethoxyphenethyl)formamide
CAS:Producto controlado<p>Applications N-(3,4-Dimethoxyphenethyl)formamide is an impurity of Tetrabenazine (T284000), an antipsychotic.<br>References Schwartz, D., et al.: Biochem. Pharmacol., 15, 645 (1966),<br></p>Fórmula:C11H15NO3Forma y color:NeatPeso molecular:209.242Zebularine
CAS:Producto controlado<p>Applications It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.<br>References Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991), Ueki, T., et al.: Cancer Res., 60, 1835 (2000),Sherr, C., et al.: Cell, 116, 235 (2004), Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),<br></p>Fórmula:C9H12N2O5Forma y color:NeatPeso molecular:228.202,5-Pyridinedicarboxylic Acid
CAS:Producto controlado<p>Applications Used in the preparation of new 2,5-pyridinedicarboxylic acids derivatives as antiviral agents.<br>References Pocker, Y., et al.: Biochemistry, 19, 2045 (1980), Flint, D., et al.: J. Biol. Chem., 268, 22369 (1993),<br></p>Fórmula:C7H5NO4Forma y color:NeatPeso molecular:167.12[1-(2-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:263.1700134277344Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Fórmula:C15H19N5Pureza:99.74%Forma y color:SolidPeso molecular:269.35(S)-4-(2,4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine
CAS:Pureza:95.0%Peso molecular:320.35998535156252-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:273.309997558593754-(4-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:354.25100708007812-[4-(3-chlorophenyl)piperazin-1-yl]-6-methyl-3,4-dihydropyrimidin-4-one
CAS:Pureza:98%Peso molecular:304.77999877929691-(4-((6-CHLORO-2-METHYLPYRIMIDIN-4-YL)AMINO)-3-FLUOROPHENYL)-3-(4-FLUOROPHENYL)UREA
Pureza:95.0%Peso molecular:389.79000854492192-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-isopropylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:285.3070068359375N-(4,6-Dimethylpyrimidin-2-yl)-N-methylbenzene-1,4-diamine
CAS:Fórmula:C13H16N4Pureza:95.0%Forma y color:SolidPeso molecular:228.2993-Methyl-1H-purine-2,6(3H,7H)-dione
CAS:Fórmula:C6H6N4O2Pureza:95%Forma y color:Solid, Light yellow powderPeso molecular:166.14N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide hydrate
CAS:Pureza:98+%Peso molecular:373.36898803710944-(2,4-dimethoxyphenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:335.40701293945315-Cyclopropyl-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidin-4-amine
CAS:Pureza:95.0%Peso molecular:360.395996093754-(furan-2-yl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:327.33999633789064-(4,6-Dimethoxypyrimidin-2-yl)benzoic acid
CAS:Fórmula:C13H12N2O4Pureza:95.0%Forma y color:SolidPeso molecular:260.249
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