Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8898 productos de "Derivados de Purinas y Pirimidinas"
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6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
CAS:Fórmula:C5H4N2O3SForma y color:No data available.Peso molecular:172.16N2-ISOBUTYRYL-2'-O-METHYL-GUANOSINE
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:367.361999511718754-[6-(3-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.315002441406251-(3-(BENZO[D]THIAZOL-2-YL)-4-HYDROXYPHENYL)-3-PHENYLUREA
CAS:Pureza:95.0%Peso molecular:361.42001342773444-(furan-2-yl)-6-[4-(propan-2-yl)phenyl]pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:279.3429870605469Thyroxine-13C6 4'-O-β-D-Glucuronide Disodium Salt
CAS:Producto controladoFórmula:C1513C6H17I4NNa2O10Forma y color:NeatPeso molecular:1002.91Methotrexate-Cadaverine-Biotin Conjugate
Producto controlado<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C35H48N12O6SPureza:>85%Forma y color:NeatPeso molecular:764.94-(3,4-dimethylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:281.38000488281256-CHLORO-1-(4-METHOXYBENZYL)-3-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
CAS:Pureza:95.0%Peso molecular:280.7099914550781Ref: 10-F506034
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarRef: 10-F344947
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarChloromethyl Isopropyl Carbonate
CAS:Producto controlado<p>Stability Moisture sensitive<br>Applications Chloromethyl Isopropyl Carbonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackman, R., et al.: Bioorg. Med. Chem., 15, 5519 (2007), Baudy, R., et al.: J. Med. Chem., 52, 771 (2009),<br></p>Fórmula:C5H9ClO3Forma y color:NeatPeso molecular:152.58Theophylline-7-acetic acid
CAS:Fórmula:C9H10N4O4Pureza:98%Forma y color:Solid, White to almost white powderPeso molecular:238.203(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate
CAS:Pureza:97%Peso molecular:571.5609741210938Ref: 10-F790039
1gA consultar5gA consultar10gA consultar25gA consultar100gA consultar250mgA consultarMethotrexate γ-Methyl Ester
CAS:Producto controlado<p>Impurity Methotrexate EP Impurity H<br>Applications Methotrexate γ-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C21H24N8O5Forma y color:NeatPeso molecular:468.47Succinimide
CAS:<p>Applications Succinimide is a reagent that is used in the synthesis of Lumiflavin (L473900), which is a toxic photolysis product of vitamin B2 (R415000).<br>References Zhao, X. et al.: Chemosphere, 63, 1116 (2006); Litke, S.V. et al.: Khim. Fiz., 10, 48 (1991); Ye, W. et al.: Guang. Yaox. Xueb., 12, 175 (1996);<br></p>Fórmula:C4H5NO2Forma y color:White To Off-WhitePeso molecular:99.09Regadenoson
CAS:Producto controlado<p>Applications Regadenoson is a selective and potent A2A adenosine receptor agonist (1). The adenosine A2A receptor is a G-protein-coupled receptor and a key therapeutic target for oncologic, inflammatory, Parkinson's and cardiovascular diseases (2). In rodent studies, it has been shown that co-administration of Regadenoson with Temozolomide (T017775) can increase Temozolomide concentration in the brain (3).<br>References (1) Gao, Z., et al.: J Pharmacol Exp Ther. 298, 209 (2001) (2) Yuan, G., et al.: Expert Opin Drug Discov. 10, 63 (2015) (3) Jackson, S., et al.: J Neurooncol. 126, 433 (2016)<br></p>Fórmula:C15H18N8O5Forma y color:Off WhitePeso molecular:390.35Ref: 10-F719483
1gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarRef: 10-F527886
1gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultarMethotrexate (1 mg/mL in Methanol with 0.1N NaOH)
CAS:Fórmula:C20H22N8O5Forma y color:Single SolutionPeso molecular:454.44Dihydro Caffeic Acid 3-O-β-D-Glucuronide Diammonium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Dihydro Caffeic Acid 3-O-β-D-Glucuronide is a glucuronide metabolite of Caffeic Acid (C080000).<br>References Clifford, M., et al.: J .Agric. Food Chem., 53, 3821 (2005), Lafay, S., et al.: J. Nutr., 136, 1192 (2006), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008)<br></p>Fórmula:C15H18O10•2NH3Forma y color:NeatPeso molecular:358.30217034-(3-fluorophenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:271.30999755859375Memantine-Glucose Adduct
Producto controladoFórmula:C18H31NO5Forma y color:NeatPeso molecular:341.442N-[2-[[[[1-Methyl-5-[(triphenylmethyl)amino]-1H-pyrazol-4-yl]amino]carbonyl]amino]ethyl]carbamic acid tert-butyl ester
CAS:Pureza:97%Peso molecular:540.6680297851562Ref: 10-F863727
1g16,00€5g45,00€10g87,00€1kg2.694,00€25g196,00€50g287,00€100g507,00€250g994,00€500g1.580,00€250mgA consultar2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid
CAS:Producto controlado<p>Applications 2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), an xanthine oxidase/ xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.<br>References Kadivar, M.H.,e t al.: J. Pharm. Biomed. Anal., 56, 749 (2011);<br></p>Fórmula:C16H17NO5SForma y color:White SolidPeso molecular:335.377-Hydroxy Methotrexate Ammonium
CAS:Producto controlado<p>Applications 7-Hydroxy Methotrexate Ammonium Salt is a metabolite of Methotrexate (M260675), which is used as an antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H22N8O6·NH3Forma y color:Yellow To BrownPeso molecular:487.47N2-Methylpyrimidine-2,5-diamine
CAS:Forma y color:Solid, Brown solidPeso molecular:124.147003173828126-METHYL-N1-(3-METHYL-1-(6-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-PYRAZOL-5-YL)BENZENE-1,3-DIAMINE
CAS:Pureza:95.0%Peso molecular:309.37701416015625N-Butyldeoxynojirimycin Hydrochloride
CAS:Producto controlado<p>Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.<br>References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),<br></p>Fórmula:C10H21NO4·ClHForma y color:NeatPeso molecular:255.746-Chloro-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
CAS:Pureza:97%Peso molecular:199.58999633789062Ref: 10-F657715
1gA consultar5gA consultar10gA consultar2.5gA consultar100mgA consultar250mgA consultar5-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS:Pureza:95.0%Peso molecular:347.067465668Tert-Butyl (6-(hydroxymethyl)pyrimidin-4-yl)carbamate
CAS:Pureza:95.0%Peso molecular:225.24800109863286-Amino-1,3-dipropyl-5-nitrosouracil
CAS:Producto controlado<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>Fórmula:C10H16N4O3Forma y color:NeatPeso molecular:240.261,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Producto controlado<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Fórmula:C14H13NOForma y color:WhitePeso molecular:211.26(R)-9-[2-(Hydroxypropyl] Adenine(Desphosphoryl Tenofovir)
CAS:Producto controlado<p>Applications (R)-9-[2-(Hydroxypropyl] Adenine (Desphosphoryl Tenofovir) (cas# 14047-28-0) is a useful reagent for preparing the antiviral drug tenofovir.<br>References Dietz, J.-P., et al.: ChemRxiv, 1 (2020)<br></p>Fórmula:C8H11N5OForma y color:NeatPeso molecular:193.219-(2-Propenyl)adenine
CAS:Producto controlado<p>Applications 9-(2-Propenyl)adenine is an N-substituted purine used in the preparation of mesityl dihydroisoxazolyl homo-N-nucleosides.<br>References Thalassitis, A. et al.: Bioorg. Med. Chem. Lett., 19, 6433 (2009); Chiacchio, U. et al.: Tetrahedron, 60, 441 (2004)<br></p>Fórmula:C8H9N5Forma y color:NeatPeso molecular:175.19
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