Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8898 productos de "Derivados de Purinas y Pirimidinas"
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4-Chloro Kynurenine-13C2,15N
CAS:Producto controlado<p>Applications 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.<br>References Leeson, P., et al.: J. Med. Chem., 37, 4053 (1994), Hilmas, C., et al.: J. Neurosci., 2001, 21, 7463 (2001), Palmer, G., et al.: Curr. Drug Targets, 2, 241 (2001), Wu, H., et al.: Exp. Neurol., 177, 222 (2002),<br></p>Fórmula:C813C2H11ClN15NO3Forma y color:NeatPeso molecular:245.643-Nitro-L-tyrosine-d3
CAS:Producto controlado<p>Applications A labelled marker for peroxynitrite. Oxidant and cytotoxic agent.<br>References Sekiguchi, M., et al.: Brain Res., 978, 228 (2003), van den Tweel, E., et al.: J. Neurobiol., 167, 64 (2005), Shirakura, T., et al.: Biol. Pharm. Bull., 28, 1658 (2005),<br></p>Fórmula:C9D3H7N2O5Forma y color:NeatPeso molecular:229.2N-(9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide hydrate
CAS:Pureza:98+%Peso molecular:373.36898803710946-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
CAS:Fórmula:C5H4N2O3SForma y color:No data available.Peso molecular:172.162-Oxo Clopidogrel Hydrochloride(Mixture of Diastereomers)
CAS:Producto controlado<p>Applications The essential intermediate metabolite from which the active metabolite of Clopidogel is formed.<br>References Feliste, R., et al.: Thromb. Res., 48, 403 (1987), Savi, P., et al.: Biochem. Pharmacol., 44, 527 (1992), Herbert, J., et al.: Cardiovasc Drug. Rev., 11, 180 (1993), Sugidachi, A., et al.: B. J. Pharmacol., 132, 47 (2001)<br></p>Fórmula:C16H17Cl2NO3SForma y color:NeatPeso molecular:374.28(S)-Tenofovir Disoproxil Fumarate
CAS:Producto controlado<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Fórmula:C19H30N5O10P·C4H4O4Forma y color:White SolidPeso molecular:635.52Chloromethyl Ethyl Carbonate
CAS:Producto controlado<p>Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.<br>References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);<br></p>Fórmula:C4H7ClO3Forma y color:Colourless OilyPeso molecular:138.555-(4-Fluorophenyl)-2-methyl-4-(4-pyridyl)-1h-pyrimidin-6-one
CAS:Pureza:98%Peso molecular:281.2900085449219N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine
CAS:Pureza:95.0%Peso molecular:350.37799072265625Ref: 10-F431587
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultarFebuxostat 2-Butyl Isomer
CAS:Producto controlado<p>Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C16H16N2O3SForma y color:NeatPeso molecular:316.374-(3,4-dimethylphenyl)-6-(3-methoxyphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:305.38101196289061-[3'-(Trifluoromethyl)phenyl]-3-[5''-(5'''-(trifluoromethypyridin-2'''-yl)-[1",2",4"]oxadiazol-3''-ylmethyl]urea
CAS:Pureza:95.0%Peso molecular:431.2982-((Bis(dimethylamino)methylene)amino)-1,3-dimethyl-4,5-dihydro-1H-imidazol-3-ium chloride
CAS:Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:247.770004272460947-Hydroxy Memantine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Memantine (M218000), used for the treatment of neurological disorders.<br>References Eiichi, K., et al.: Chem. Pharm. Bull., 33, 4680 (1985),<br></p>Fórmula:C12H21NO·ClHForma y color:NeatPeso molecular:231.766-Methylpurine
CAS:Pureza:95.0%Forma y color:Solid, Light yellow solidPeso molecular:134.141998291015624-(2-fluorophenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:271.30999755859375Methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
CAS:Pureza:95+%Peso molecular:320.351989746093754-(2,3-dimethoxyphenyl)-6-(5-methylfuran-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:311.341003417968756-(4-Methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS:Fórmula:C11H10N2O2SPureza:95.0%Peso molecular:234.27Thyroxine-13C6 4'-O-β-D-Glucuronide Disodium Salt
CAS:Producto controladoFórmula:C1513C6H17I4NNa2O10Forma y color:NeatPeso molecular:1002.91N4-(3-Aminophenyl)-5-fluoro-N2-(4-(2-methoxyethoxy)phenyl)pyrimidine-2,4-diamine
CAS:Pureza:98.0%Peso molecular:369.3999938964844Methyl 4-(((4-(pyridin-3-yl)pyrimidin-2-yl)amino)methyl)benzoate
CAS:Pureza:95+%Peso molecular:320.351989746093752-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Fórmula:C10H13N5O4S·x(H2O)Forma y color:Light Yellow PowderPeso molecular:299.31Acetal
CAS:<p>Stability Volatile<br>Applications Acetal is a flavouring component of Baiju and Rum. It is also a useful reactant in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Franitza, Laura, et al.: J. of Agric. and Food Chem., 64(47), 9041-9053 (2016);<br></p>Fórmula:C6H14O2Forma y color:ColourlessPeso molecular:118.17Sumatriptan
CAS:Producto controlado<p>Applications Sumatriptan is a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)<br></p>Fórmula:C14H21N3O2SForma y color:White To Light YellowPeso molecular:295.404-(2H-1,3-benzodioxol-5-yl)-6-(5-methylfuran-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:295.29800415039064-(2H-1,3-benzodioxol-5-yl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:281.27099609375[6-(3-Aminomethyl-piperidin-1-yl)-pyrimidin-4-yl]-cyclopropyl-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:283.79998779296875N-(4-((4-Chloro-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide
CAS:Pureza:95.0%Peso molecular:400.89001464843754-(2H-1,3-benzodioxol-5-yl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:319.3640136718756-Mercaptopurine Monohydrate
CAS:Producto controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Fórmula:C5H4N4S·H2OForma y color:YellowPeso molecular:170.19N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
CAS:Producto controlado<p>Applications N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);<br></p>Fórmula:C15H25N6O5PPureza:>85%Forma y color:NeatPeso molecular:400.373-Des[2-(Dimethylamino)ethyl] Zolmitriptan 3-Acetic Acid
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications The indole acetic acid metabolite of Zolmitriptan (Z639000) formed by human hepatocytes.<br>References Wild, M.J. et al.: Xenobiotica, 29, 847 (1999);<br></p>Fórmula:C14H14N2O4Forma y color:NeatPeso molecular:274.272-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:301.3699951171875
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![2-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-5-ethyl-6-methylpyrimidin-4(3H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF495922.webp&w=3840&q=75)