Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65924 productos de "Derivados de Quinazolina y Quinolina"
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3-Amino-5-(4-methoxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS:Fórmula:C13H13NO3SPureza:95.0%Peso molecular:263.313-Phenyl-1-propanol
CAS:Producto controlado<p>Impurity Alverine EP Impurity B<br>Applications 3-Phenyl-1-propanol is used as a reagent in the synthesis of Dihydrocinnamyl Cilnidipine (D448605) and is a potent aroma biotransformation product.<br>References Bosse, A.K., et al.: Food Chem., 141, 2952 (2013)<br></p>Fórmula:C9H12OForma y color:ColourlessPeso molecular:136.19Dehydronitroso Nifedipine
CAS:Producto controlado<p>Impurity Nifedipine EP Impurity B<br>Applications A photodegradation product of Nifedipine (N457000). Shown to relax contractions of the rat aortic strip induced by norepinephrine and other agonists.<br>References Hayase, N. et at.: J. Pharmac. Exp. Ther., 275, 813 (1995); De Vries, H. et al.: Photochem. Photobio., 62, 959 (1995);<br></p>Fórmula:C17H16N2O5Forma y color:NeatPeso molecular:328.32Hexametazidine
CAS:Producto controlado<p>Impurity Trimetazidine dihydrochloride EP impurity B<br>Applications Hexametazidine is an impurity of Trimetazidine (T795610). Trimetazidine impurity B. Hexametazidine can protect the myocardium from injury by ischemia and reperfusion.<br></p>Fórmula:C24H34N2O6Forma y color:NeatPeso molecular:446.54Pomalidomide
CAS:<p>Applications Pomalidomide is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Fórmula:C13H11N3O4Forma y color:YellowPeso molecular:273.24De-4-fluoro 5-Fluoro Chidamide
CAS:<p>Applications De-5-fluoro 4-Fluorochidamide is an analogue of Chidamide (CAS 743420-02-0), a hitsone deacetylase inhibitor (HDACI) that enhances gemcitabine (G305000) cytotoxicity in pancreatic cancer cells.<br>References Qiao, Z., et. al.: Biochem. Bioph. Res. Co., 434, 95 (2013)<br></p>Fórmula:C22H19FN4O2Forma y color:Off White PowderPeso molecular:390.413-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE
CAS:Pureza:97.0%Peso molecular:380.44699096679691-(1,3-Dimethyl-1H-pyrazol-4-yl)-4,4,4-trifluoro-butane-1,3-dione
CAS:Fórmula:C9H9F3N2O2Pureza:98%Forma y color:SolidPeso molecular:234.178Ticagrelor
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H28F2N6O4SForma y color:WhitePeso molecular:522.571,1'-[(1-Methylethyl)imino]bis[3-(1-naphthalenyloxy)-2-propanol
CAS:<p>Applications 1,1'-[(1-Methylethyl)imino]bis[3-(1-naphthalenyloxy)-2-propanol is an impurity of Propranolol (P831800), an β−Adrenergic blocker used as a antihypertensive and antilanginal agent.<br>References Helboe, P., et al.: J. Chromatography., 245, 229 (1982); Helboe, P., et al.: J. Chromatography., 245, 229 (1982);<br></p>Fórmula:C29H33NO4Forma y color:Off-White To BeigePeso molecular:459.58N-Nitroso Propafenone (2,2,3,3,3-Propyl-D5)
Producto controladoFórmula:C21D5H21N2O4Forma y color:NeatPeso molecular:375.473Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid
CAS:Producto controlado<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>Fórmula:C15H18F3NO4Forma y color:NeatPeso molecular:333.3cis Lacidipine
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications Z-Isomer of Lacidipine; a dihydropyridine calcium channel blocker. Antihypertensive.<br>References Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989), Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002), McCormack, A.J., et al.: Drugs, 63, 2327 (2003),<br></p>Fórmula:C26H33NO6Forma y color:NeatPeso molecular:455.54N-Nitrosomorpholine-d8
CAS:Producto controlado<p>Applications N-Nitrosomorpholine-d8 (CAS# 1219805-76-1) is a useful isotopically labeled research compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C42H8N2O2Forma y color:Light YellowPeso molecular:124.17Risperidone N-Oxide
CAS:Producto controlado<p>Applications Risperidone (R525000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References El-Sherif, Z., et al.: J. Pharm. Biomed. Anal., 36, 975 (2005), Sattanathan, P., et al.: J. Pharm. Biomed. Anal., 40, 598 (2006),<br></p>Fórmula:C23H27FN4O3Forma y color:WhitePeso molecular:426.485-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O4SForma y color:NeatPeso molecular:361.42Retigabine N-β-D-Glucuronide Sodium Salt
CAS:Producto controlado<p>Applications Sodium salt of Retigabine N-β-D-Glucuronide is the major metabolite of the antiepileptic drug Retigabine (R189050) that is produced via N-glucuronidation in humans.<br>References Hiller, A. et al.: Drug Metab. Dispos., 27, 605 (1999); Borlak, J. et al.: Metab. Clin. Exp., 55, 711 (2006); McNeilly, P.P. et al.: Zenobiotica, 27, 431 (1997);<br></p>Fórmula:C22H25FN3NaO8Forma y color:NeatPeso molecular:501.44Ezetimibe Diol Impurity
CAS:Producto controladoFórmula:C24H25F2NO3Forma y color:NeatPeso molecular:413.46Deshydroxyethoxy Ticagrelor
CAS:<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Fórmula:C21H24F2N6O3SForma y color:White To Off-WhitePeso molecular:478.52Ioversol
CAS:Producto controlado<p>Applications Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium).<br>References Wilkins, R.A., et al.: Invest. Radiol., 24, 781 (1989), Kaufman, A.J., et al.: Urol. Radiol., 12, 56 (1990),<br></p>Fórmula:C18H24I3N3O9Forma y color:Off-WhitePeso molecular:807.115-(4-CYCLOPROPYL-4H-1,2,4-TRIAZOL-3-YL)THIOPHEN-3-AMINE
CAS:Pureza:95.0%Peso molecular:206.27000427246094Acetamiprid
CAS:Producto controlado<p>Applications A novel neonicotinid insecticide against Holotrichia consanguinea in sugarcane. Reports show that when exposed to neonicotinid pesticides honeybees have problems returnibg home after foraging and bumblebee colonies grow poorly and produce fewer queens. Used in Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srivastava, A., et al.: Indian Sugar, 32, 673 (1983), Fleming, R., et al.: J. Econ. Entomol., 78, 1179 (1985), Rao, Ch.V., et al.: Pestology, 35, 47 (2011), Chem. and Eng. News 90: 10 (2012)<br></p>Fórmula:C10H11ClN4Forma y color:Colourless To WhitePeso molecular:222.674,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxylic Acid Methyl Ester
CAS:Producto controladoFórmula:C26H26N4O5Forma y color:NeatPeso molecular:474.508(R)-4-Hydroxy Propranolol Hydrobromide
CAS:Producto controlado<p>Applications The main metabolite of (R)-Propranolol.<br>References Shwed, J., et al.: Xenobiotica, 22, 973 (1992), Fujita, K., et al.: Biol. Pharm. Bull., 22, 446 (1999), Walle, U., et al.: Drug Metab. Dispos., 30, 564 (2002),<br></p>Fórmula:C16H21NO3·HBrForma y color:NeatPeso molecular:356.25(3S,3'S)-4,4'-(7-Chloropyrido[2,3-d]pyrimidine-2,4-diyl)bis(3-methylmorpholine)
CAS:Pureza:95.0%Peso molecular:363.85000610351565-Chloro-3-(4-chloro-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS:Pureza:95.0%Peso molecular:317.1700134277344(S)-9-Hydroxy Risperidone
CAS:Producto controlado<p>Applications The S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Fórmula:C23H27FN4O3Forma y color:NeatPeso molecular:426.48(2S,3S,5S)-5-Amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride
CAS:Producto controlado<p>Applications (2S,3S,5S)-5-amino-1,6-diphenyl-2-([[thiazol-5-ylmethoxy)carbonyl]amino]hexan-3-yl 2-(3-((2-isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate Hydrochloride, is a prodrug of Ritonavir (R535000), which is a selective HIV protease inhibitor.<br>References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006);<br></p>Fórmula:C37H48N6O5S2•xHClForma y color:NeatPeso molecular:720.94Sitagliptin
CAS:Producto controlado<p>Applications Sitagliptin (cas# 486460-32-6) is a useful research chemical.<br></p>Fórmula:C16H15F6N5OForma y color:Off-WhitePeso molecular:407.31Levetiracetam
CAS:<p>Applications The (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992); Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996); Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000)<br></p>Fórmula:C8H14N2O2Forma y color:NeatPeso molecular:170.21Levetiracetam-d3
CAS:Producto controladoFórmula:C8H11D3N2O2Forma y color:White To Off-WhitePeso molecular:173.23Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:95.0%Peso molecular:367.3999938964844Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Producto controlado<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Fórmula:C31H28N2OForma y color:NeatPeso molecular:444.574-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride
CAS:Pureza:98%Peso molecular:400.63000488281252,6-Dimethyl-quinoline-3-carboxylic acid
CAS:Fórmula:C12H11NO2Pureza:95.0%Forma y color:SolidPeso molecular:201.225Cabozantinib L-Malate Salt
CAS:Producto controlado<p>Applications Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.<br>References Camp, R., et al.: Cancer, 86, 2259 (1999), Morello, S., et al.: J. Cell Physiol., 189, 285 (2001), Zhang, Y., et al.: Oncogene, 21, 217 (2002), Wells, S., et al.: J. Clin. Oncol., 28, 767 (2010),<br></p>Fórmula:C28H24FN3O5·C4H6O5Forma y color:NeatPeso molecular:635.59Olanzapine-d3
CAS:Producto controlado<p>Applications Deuterated Olanzapine, a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C172H3H17N4SForma y color:Yellow To BrownPeso molecular:315.45(2S,2'S)-1,1'-[[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)imino]bis(1-oxo-2,1-ethanediyl)]bis-2-pyrrolidinecarbonitrile
CAS:Fórmula:C24H33N5O3Forma y color:Off-WhitePeso molecular:439.55Blonanserin-d5
CAS:Producto controlado<p>Applications Labelled Blonanserin (B595850). A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.<br>References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),<br></p>Fórmula:C23H25D5FN3Forma y color:NeatPeso molecular:372.53N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Producto controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Forma y color:NeatPeso molecular:425.43Safinamide Mesylate
CAS:Producto controlado<p>Applications Safinamide mesylate is a potent and selective MAO-B inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C17H19FN2O2·CH4O3SForma y color:White To Off-WhitePeso molecular:398.45(3-Cyclohexyl)propyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone
CAS:Pureza:97.0%Peso molecular:308.440002441406252-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Fórmula:C13H11NOSForma y color:Grey To BrownPeso molecular:229.30Dehydro Nimodipine
CAS:Producto controlado<p>Impurity Nimodipine EP Impurity A; Nimodipine USP Related Compound A<br>Stability Light Sensitive<br>Applications Dehydro Nimodipine (Nimodipine EP Impurity A; Nimodipine USP Related Compound A) is the dehydrogenated analogue and the major metabolite of the calcium channel blocker Nimodipine (N478200).<br>References Scherling, D. et al.: Arzneim.-Forsch., 41, 392 (1991); Liu, X. et al.: Yaox. Xueb., 35, 257 (2000); Eicher, H. et al.: Arch. Gerontol. Geriat., 14, 309 (1992);<br></p>Fórmula:C21H24N2O7Forma y color:Light YellowPeso molecular:416.42Everolimus
CAS:Producto controlado<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C53H83NO14Pureza:~90%Forma y color:NeatPeso molecular:958.22(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS:Producto controladoFórmula:C18H15NO4Forma y color:Light YellowPeso molecular:309.323-Amino-5-biphenyl-4-yl-thiophene-2-carboxylic acid methyl ester
CAS:Forma y color:SolidPeso molecular:309.3800048828125Leflunomide-d4
CAS:Producto controlado<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Fórmula:C12D4H5F3N2O2Forma y color:NeatPeso molecular:274.23Chlorpromazine N-Oxide Maleic Acid Salt
CAS:Producto controlado<p>Applications Chlorpromazine N-Oxide Maleic Acid Salt is an impurity of Chlorpromazine (C424750) which has antiemetic; antipsychotic properties.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)<br></p>Fórmula:C21H23ClN2O5SForma y color:NeatPeso molecular:450.94Olanzapine
CAS:Producto controlado<p>Applications Olanzapine is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Neuroprotective product.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H20N4SForma y color:Light Yellow CrystallinePeso molecular:312.43Desisopropyl Atrazine
CAS:Producto controlado<p>Applications A metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Fórmula:C5H8ClN5Forma y color:Off-WhitePeso molecular:173.604-[6-(4-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.31500244140625(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
CAS:Producto controladoFórmula:C22H20OForma y color:NeatPeso molecular:300.394Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
CAS:Producto controlado<p>Applications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>Fórmula:C292H8H23N7O·CH4O3SForma y color:NeatPeso molecular:597.762-(2-Ethoxyphenyl)quinoline-4-carboxylic acid
CAS:Forma y color:SolidPeso molecular:293.32199096679698-Hydroxy Amoxapine
CAS:<p>Applications A metabolite of Amoxapine.<br>References Hansen, E., et al.: Drug Metab. Dispos.,15, 97 (1987), Hansen, E., et al.: Xenobiotica, 25, 1081 (1995), Moody, J., et al.: Drug Metab. Dispos., 27, 1157 (1999),<br></p>Fórmula:C17H16ClN3O2·ClHForma y color:NeatPeso molecular:366.24(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methanol
CAS:Fórmula:C12H18BNO3Pureza:96.0%Forma y color:SolidPeso molecular:235.09Pamabrom
CAS:Producto controlado<p>Applications A diuretic used to reduce menstrual pains.<br>References Varga, J., et al.: Mol. Immunol., 28, 641 (1991), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Ibrahim, H., et al.: Drug Discov. Ther., 3, 168 (2009),<br></p>Fórmula:C7H7BrN4O2·C4H11NOForma y color:NeatPeso molecular:348.20Tetramethylurea
CAS:<p>Applications Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds.<br>References Lüttringhaus, A., et al.: Angew. Chem. Int. Ed. Engl., 3, 260 (1964)<br></p>Fórmula:C5H12N2OForma y color:NeatPeso molecular:116.162-(6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid
CAS:Pureza:97%Peso molecular:313.7399902343755-(p-Methylphenyl)-5-phenylhydantoin
CAS:<p>Applications An antibody agent.<br>References Rowell, F. J., et al.: Immunochemistry, 13, 891 (1976),<br></p>Fórmula:C16H14N2O2Forma y color:NeatPeso molecular:266.291,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine
CAS:Producto controlado<p>Impurity Ranitidine EP Impurity J<br>Applications 1,1’-N-[Methylenebis(sulphanediylethylene)]bis(N’-methyl-2-nitroethene-1,1-diamine (Ranitidine EP Impurity J) is a Ranitidine (R120000) impurity.<br></p>Fórmula:C11H22N6O4S2Forma y color:Off-White To BeigePeso molecular:366.46Nilotinib Regio Isomer
CAS:Producto controlado<p>Applications Nilotinib Regio Isomer is a more potent Bcr-Abl tyrosine kinase inhibitor for the treatment of patients with myelogenous leukemia. It is a COVID19-related research product.<br>References Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Bilbe, G.,et al.: From PCT Int. Appl. (2005), WO 2005039586 A1 20050506<br></p>Fórmula:C28H22F3N7OForma y color:NeatPeso molecular:529.52N-Desmethyl Sildenafil Hemicitrate
CAS:Producto controlado<p>Applications N-Desmethyl Sildenafil Hemicitrate is an impurity of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.<br>References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)<br></p>Fórmula:C48H64N12O15S2Forma y color:NeatPeso molecular:1113.22Ref: 10-F469193
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarSulindac Sulfone-d6
CAS:Producto controlado<p>Applications Labelled analogue of Sulindac Sulfone, an active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.<br>References Piazza, G.A. et al.: Cancer Res., 55, 3310 (1995);<br></p>Fórmula:C20H11D6FO4SForma y color:NeatPeso molecular:378.45N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-carbamimidic Acid Methyl Ester
CAS:Producto controlado<p>Impurity Cimetidine EP Impurity B<br>Applications N-Cyano-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-carbamimidic Acid Methyl Ester which is an impurity of Cimetidine (C441650), which acts as a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output (1).<br>References 1. Brimblecombe, R. et al.: J. Int. Med. Res. 1975 Mar:3(2) 86-92<br></p>Fórmula:C10H15N5OSForma y color:White To Off-WhitePeso molecular:253.322-(1-Amino-2-methylpropyl)-3-benzyl-7-chloroquinazolin-4(3H)-one
CAS:Pureza:98%Peso molecular:341.8399963378906Hydroxy Flutamide
CAS:Producto controlado<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Fórmula:C11H11F3N2O4Forma y color:Off White SolidPeso molecular:292.21Ramifenazone
CAS:<p>Applications Analgesic, antipyretic, anti-inflammatory.<br>References Tubaro, E., et al.: Arzneim.-Forsch., 20, 1024 (1970),<br></p>Fórmula:C14H19N3OForma y color:NeatPeso molecular:245.32Aripiprazole
CAS:Producto controlado<p>Applications Aripiprazole is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.<br>References (1) Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998)(2) Shiokawa, M., et al.: Eur.J.Pharmacol. 570, 108 (2007)(3) Oshiro, Y., et al.: J. Med. Chem. 41, 658 (1998)(4) Ozdemir, V., et al.: Curr Opin Investig Drugs. 3, 113 (2002)<br></p>Fórmula:C23H27Cl2N3O2Forma y color:NeatPeso molecular:448.39Vildagliptin Carboxylic Acid Lithium Salt Hydrate
CAS:Producto controlado<p>Applications The major metabolite of Vildagliptin (V305000).<br>References Reimer, M.K., et al.: Eur. J. Endocrinol., 146, 717 (2002), Villhauer, E.B., et al.: J. Med. Chem., 46, 2774 (2003), Ahren, B., et al.: J. Clin. Endocrinol. Metab., 85, 2078 (2004), He, H., et al.: Drug Metab. Dispos., 37, 545 (2009),<br></p>Fórmula:C17H25LiN2O4Forma y color:NeatPeso molecular:328.33Risperidone Z-Oxime Impurity
CAS:Producto controlado<p>Impurity Risperidone EP Impurity B<br>Applications Risperidone Z-Oxime (Risperidone EP Impurity B) is an impurity of Risperidone (R525000). Risperidone impurity per USP.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C23H28F2N4O2Forma y color:NeatPeso molecular:430.49Prochlorperazine
CAS:Producto controlado<p>Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.<br>References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),<br></p>Fórmula:C20H24ClN3SForma y color:YellowPeso molecular:373.94Propylthiouracil
CAS:Producto controlado<p>Applications Antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Fórmula:C7H10N2OSForma y color:White To Off-WhitePeso molecular:170.237-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone is used in the synthesis of aripiprazole, an antipsychotic oral drug used in the treatment of Schizophrenia.<br>References Bonacorsi, S. et al.: J. Label. Comp. Radiopharm., 49, 1 (2006); Morita, Seiji; K. et al.: Tetrahedron, 54, 4811 (1998);<br></p>Fórmula:C13H16ClNO2Forma y color:Off-WhitePeso molecular:253.725-Chloro-Vortioxetine Hydrobromide
CAS:Producto controlado<p>Applications 5-Chloro-Vortioxetine is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.<br>References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Fórmula:C18H22BrClN2SForma y color:NeatPeso molecular:413.81,2,3,4-Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol
CAS:Producto controladoFórmula:C18H21NO4Forma y color:NeatPeso molecular:315.36Norfloxacin-d5
CAS:Producto controlado<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Fórmula:C162H5H13FN3O3Forma y color:NeatPeso molecular:324.36
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