Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65580 productos de "Derivados de Quinazolina y Quinolina"
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Valsartan Benzyl Ester
CAS:<p>Impurity Valsartan USP Related Compound C<br>Applications Valsartan (V095750) intermediate. Valsartan USP Related Compound C.<br>References Cramer., et al.: J. Med. Chem., 42, 3919 (1999),<br></p>Fórmula:C31H35N5O3Forma y color:NeatPeso molecular:525.64Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Producto controlado<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Fórmula:C11H13N2O3ClForma y color:NeatPeso molecular:256.68(S) FTY720 Phosphate
CAS:<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005<br></p>Fórmula:C19H34NO5PForma y color:WhitePeso molecular:387.45Aripiprazole-d8
CAS:Producto controlado<p>Applications Aripiprazole-d8 is a deuterated version of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Fórmula:C232H8H19Cl2N3O2Forma y color:Off White SolidPeso molecular:456.43Rebamipide 3-Chloro Impurity (>80%)
CAS:Producto controlado<p>Applications Rebamipide 3-Chloro Impurity (CAS# 90098-05-8) is a useful research chemical compound.<br></p>Fórmula:C19H15ClN2O4Pureza:>80%Forma y color:White To Off-WhitePeso molecular:370.7864N-Methylnitroacetamide
CAS:Producto controlado<p>Impurity Ranitidine EP Impurity H<br>Applications N-Methylnitroacetamide (Ranitidine EP Impurity H) is a degradation product of Ranitidine (R120000).<br>References Sharma, N. et al.: Sci. Pharmac., 79, 309 (2011); Haywood, P.A. et al.: J. Chem. Soc., 5, 951 (1987);<br></p>Fórmula:C3H6N2O3Forma y color:NeatPeso molecular:118.09Maropitant Citrate Salt
CAS:<p>Applications Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.<br>References Boscan, P. et al.: Am. J. Vet. Res., 72, 1576 (2011);<br></p>Fórmula:C32H40N2O·C6H8O7Forma y color:Off White SolidPeso molecular:660.8Cinnarizine
CAS:<p>Applications Calcium channel blocker with antiallergic and anti-vasoconstricting activity. Antihistaminic.<br>References Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)<br></p>Fórmula:C26H28N2Forma y color:NeatPeso molecular:368.512,2,2-Trifluoroethyl 2,5-Bis(2,2,2-trifluoroethoxy)benzoate
CAS:Producto controlado<p>Applications Intermediate in the production of antiarrhythmic N-(Piperidylalkyl)trifluoroethoxybenzamides. Possible Flecainide impurity.<br>References Banitt, E., et al.: J. Med. Chem., 20, 821 (1977),<br></p>Fórmula:C13H9F9O4Forma y color:NeatPeso molecular:400.19(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-2-one
CAS:Producto controlado<p>Applications Labelled Ezetimibe (E975000), an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Fórmula:C242H4H17F2NO3Forma y color:NeatPeso molecular:413.457-Hydroxy Risperidone
CAS:Producto controladoFórmula:C23H27FN4O3Forma y color:NeatPeso molecular:426.481-CYCLOPROPYL-6,7,8-TRIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:283.20599365234375Aripiprazole-d8 (Butyl-d8)
CAS:Producto controladoFórmula:C232H8H19Cl2N3O2Forma y color:White To Off-WhitePeso molecular:456.432-(3-hydroxyphenyl)-6-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:279.2950134277344rac-trans-Ambroxol-d5
CAS:Producto controlado<p>Applications A labelled metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C13H13D5Br2N2OForma y color:NeatPeso molecular:383.133-(4-Fluoro-phenyl)-1-methyl-1H-pyrazole-4-carbaldehyde
CAS:Fórmula:C11H9FN2OPureza:95.0%Forma y color:Solid, Light yellow powderPeso molecular:204.2043-[6-(Trifluoromethyl)pyridin-3-yl]propanoic acid
CAS:Fórmula:C9H8F3NO2Pureza:95.0%Forma y color:SolidPeso molecular:219.163Meloxicam
CAS:<p>Applications Preferential cyclooxygenase (COX-2) inhibitor. Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Fórmula:C14H13N3O4S2Forma y color:Light YellowPeso molecular:351.40Carboxymefloquine-d3
CAS:Producto controlado<p>Applications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050).<br>References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),<br></p>Fórmula:C12H2D3F6NO2Forma y color:NeatPeso molecular:312.18Alogliptin Benzoate
CAS:<p>Applications Alogliptin Benzoate is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Alogliptin Benzoate is used in the treatment of type 2 diabetes.<br>References Wang, Y., et. al.: Drugs Future, 33, 7 (2008); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)<br></p>Fórmula:C18H21N5O2·C7H6O2Forma y color:NeatPeso molecular:461.51N-Nitroso Desmethyl Olopatadine
Producto controladoFórmula:C20H20N2O4Forma y color:NeatPeso molecular:352.384Ethyl 5-{[1,1'-biphenyl]-4-yl}-1H-pyrazole-3-carboxylate
CAS:Pureza:95.0%Peso molecular:292.3380126953125N,N'-Methylene Ambroxol Hydrochloride
CAS:Producto controlado<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Fórmula:C14H18Br2N2O·ClHForma y color:White To Off-WhitePeso molecular:426.57N-Benzyl Hydroxymedetomidine
CAS:Producto controlado<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Fórmula:C20H22N2OForma y color:NeatPeso molecular:306.41-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Fórmula:C17H18N4Forma y color:Light Yellow To BrownPeso molecular:278.35Benzhydrol
CAS:<p>Impurity Diphenhydramine EP Impurity D<br>Applications Intermediate in the preparation of Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Fórmula:C13H12OForma y color:WhitePeso molecular:184.23DL-threo-Ritalinic Acid-d10 (Major)
CAS:Producto controladoFórmula:C13H7D10NO2Forma y color:NeatPeso molecular:229.34(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);<br></p>Fórmula:C7H9ClN2OForma y color:NeatPeso molecular:172.614-Amino-2,6-dichloro-α-(4-chlorophenyl)benzeneacetonitrile
CAS:Producto controlado<p>Applications This compound is used in the synthesis of Diclazuril (D436200) and diclazuril derivatives.<br></p>Fórmula:C14H9Cl3N2Forma y color:NeatPeso molecular:311.592-(3,5-Dimethoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:320.35998535156252-Pyridin-2-yl-benzofuran-5-carboxylic acid methyl ester
Pureza:95.0%Peso molecular:253.25700378417972-Cyclopropyl-quinoline-4-carboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:213.235992431640622-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide
CAS:Producto controladoFórmula:C11H10ClN3OSForma y color:NeatPeso molecular:267.73Risperidone E-Oxime
CAS:Producto controladoFórmula:C23H28F2N4O2Forma y color:NeatPeso molecular:430.49Minoxidil Sulfate-d10
CAS:Producto controlado<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Fórmula:C9H5D10N5O4SForma y color:NeatPeso molecular:299.37[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
CAS:Producto controladoFórmula:C15H20O3Forma y color:NeatPeso molecular:248.322-METHOXY-5-(5-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOL-1-YL)PHENOL
CAS:Pureza:95.0%Peso molecular:317.34799194335944-Chloro-1H -pyrazol-3-ylamine hydrochloride
CAS:Fórmula:C3H5Cl2N3Pureza:95.0%Forma y color:SolidPeso molecular:153.993,4-Dimethoxybenzoic Acid (Veratric Acid)
CAS:Producto controlado<p>Applications Veratric Acid is a derivative of Protocatechuic Acid. Veratric Acid is a reagent used in the production of antimicrobial agents, antifeedants, and a variety of other biologically active compounds.<br>References Alissandrakis, E., et al.: Eur. Food Res. Technol., 229, 365 (2009), Spaccini, R., et al.: Soil Biol. Biochem., 41, 1164 (2009), Narasimhan, B., et al.: Eur. J. Med. Chem., 44, 689 (2009), Pereira, L., et al.: J. Biotechnol., 139, 68 (2009),<br></p>Fórmula:C9H10O4Forma y color:NeatPeso molecular:182.172-(Aminomethyl)-1-ethylpyrrolidine
CAS:Producto controladoFórmula:C7H16N2Forma y color:Colourless To Light YellowPeso molecular:128.222-Nitrobenzaldehyde
CAS:<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Fórmula:C7H5NO3Forma y color:NeatPeso molecular:151.123-Methyl-1-{4-[4-(propan-2-yl)benzenesulfonyl]phenyl}-1H-pyrazol-5-amine
CAS:Pureza:97%Peso molecular:355.45999145507819-Piperazino Levofloxacin Impurity
CAS:Producto controlado<p>Applications A degradation product of Levofloxacin (L360000). Levofloxacin impurity.<br>References ierens, C., et al.: J. Pharm. Biomed. Anal., 22, 763 (2000), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003), Liang, Y., et al.: Anal. Chim. Acta, 510, 21 (2004),<br></p>Fórmula:C18H20FN3O4Forma y color:NeatPeso molecular:361.3683-acetyl-6-chloro-4-(4-fluorophenyl)quinolin-2(1H)-one
CAS:Pureza:95.0%Peso molecular:315.7300109863281Glycopyrrolate Bromide-d3 (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications Labelled analogue of Glycopyrrolate Bromide, a novel pharmaceutical compound based on PDE IV inhibitors. Glycopyrrolate Bromide is used in the treatment of respiratory complaints.<br>References Gomez, et al.: Br. J. Anaesth., 74, 549 (1995);<br></p>Fórmula:C19H25D3NO3·BrForma y color:NeatPeso molecular:401.35Thiophene, 2,2′,2′′,2′′′-(1,2-ethenediylidene)tetrakis-
CAS:Pureza:98%Peso molecular:356.535-Hydroxy Omeprazole-d3 Sodium Salt
CAS:Producto controladoFórmula:C17H15D3N3NaO4SForma y color:White To Light YellowPeso molecular:386.425’-Hydroxymethyl 5’-Desmethyl Meloxicam
CAS:Fórmula:C14H13N3O5S2Forma y color:NeatPeso molecular:367.40Gabapentin-d4
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9D4H13NO2Forma y color:Off-WhitePeso molecular:175.26Celecoxib
CAS:Producto controlado<p>Applications Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C17H14F3N3O2SForma y color:NeatPeso molecular:381.37Dolutegravir O-b-D-Glucuronide Sodium salt
Fórmula:C26H26F2N3NaO11Forma y color:White To Off-WhitePeso molecular:617.49rac-Mephenytoin
CAS:Producto controlado<p>Applications rac-Mephenytoin is an anticonvulsant agent.<br>References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),<br></p>Fórmula:C12H14N2O2Forma y color:White SolidPeso molecular:218.25(S)-Naproxen
CAS:<p>Applications (S)-Naproxen is a a nonsteroidal anti-inflammatory compound with analgesic and antipyretic properties (1,2). (S)-Naproxen is also a potent COX1 inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)(2) Scott, W. W., et al.: World Neurosurg. 82, e633 (2014)<br></p>Fórmula:C14H14O3Forma y color:Off-WhitePeso molecular:230.266-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
CAS:Producto controlado<p>Applications An Intermediate in the synthesis of risperidone and iloperidone.<br></p>Fórmula:C12H13FN2OForma y color:NeatPeso molecular:220.24Ketanserin Tartrate
CAS:Producto controlado<p>Applications Ketanserin Tartrate is used in nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis for preventing a variety of diseases ranging from cancer to ischemic injury.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gohil, V. M., et al.: Nat. Biotechnol, 28, 249 (2010)<br></p>Fórmula:C22H22FN3O3·C4H6O6Forma y color:Off-WhitePeso molecular:545.518-propyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:333.388000488281255-Aminoimidazole-4-carboxamide
CAS:<p>Applications A metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Fórmula:C4H6N4OForma y color:White To Off-WhitePeso molecular:126.125-CYCLOPROPYL-1-(3,5-DICHLORO-PYRIDIN-4-YL)-1H-[1,2,3]TRIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER
CAS:Pureza:90.0%Peso molecular:327.17001342773442,2'-Dithiobis[N-methyl-benzamide]
CAS:<p>Applications Benzamide, 2,2'-dithiobis[N-methyl- (cas# 2527-58-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C16H16N2O2S2Forma y color:Light Yellow To Light BeigePeso molecular:332.44Levetiracetam-d3
CAS:Producto controladoFórmula:C8H11D3N2O2Forma y color:White To Off-WhitePeso molecular:173.234-CHLORO-1-(3-METHYLPYRIDIN-4-YL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE
CAS:Pureza:97.0%Peso molecular:245.66999816894538-(4-Isopropylpyridin-2-yl)-2-methylbenzofuro[2,3-b]pyridine
CAS:Pureza:97%Peso molecular:302.37701416015625Dehydro Nimodipine
CAS:Producto controlado<p>Impurity Nimodipine EP Impurity A; Nimodipine USP Related Compound A<br>Stability Light Sensitive<br>Applications Dehydro Nimodipine (Nimodipine EP Impurity A; Nimodipine USP Related Compound A) is the dehydrogenated analogue and the major metabolite of the calcium channel blocker Nimodipine (N478200).<br>References Scherling, D. et al.: Arzneim.-Forsch., 41, 392 (1991); Liu, X. et al.: Yaox. Xueb., 35, 257 (2000); Eicher, H. et al.: Arch. Gerontol. Geriat., 14, 309 (1992);<br></p>Fórmula:C21H24N2O7Forma y color:Light YellowPeso molecular:416.42L-Aminobutyric Acid
CAS:<p>Applications Receptor antagonist.<br>References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995),<br></p>Fórmula:C4H9NO2Forma y color:NeatPeso molecular:103.122-[2-(pyridin-4-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:273.760009765625Stiripentol-d9
CAS:Producto controlado<p>Applications An labelled epilepsy drug. It has been used as co-therapy for treatment of epilepsy. It inhibits the enzymes responsible for metabolism of other anti-convulsant agents.<br>References Laurie, D., et al.: J. Neurosci., 12, 4151 (1992), Smith, A., et al.: J. Pharmacol. Exp. Therap., 311, 601 (2004), Trojnar, M., et al.: Pharm. Rep., 57, 154 (2005), Drafts, B., et al.: J. Pharm. Exp. Ther., 318, 1094 (2006), Picton, A., et al.: Brain Res., 1165, 40 (2007),<br></p>Fórmula:C14H9D9O3Forma y color:White SolidPeso molecular:243.355-chloro-2-(1H-pyrazol-5-yl)aniline
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:193.6300048828125Macitentan
CAS:Producto controlado<p>Applications Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Fórmula:C19H20Br2N6O4SForma y color:White To Off-WhitePeso molecular:588.278-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide
CAS:Producto controlado<p>Impurity Aripiprazole Impurity 12<br>Applications 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide is an intermediate used in the preparation of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Antipsychotic. Aripiprazole Impurity 12<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Fórmula:C14H19Cl2N2·BrForma y color:NeatPeso molecular:366.122-Amino-2-[2-(4-hexylphenyl)ethyl]-1,3-propanediol
CAS:Producto controladoFórmula:C17H29NO2Forma y color:NeatPeso molecular:279.422-Descyano-2-ethyl Formyl-tofacitinib
CAS:Producto controlado<p>Applications 2-Descyano-2-ethyl Formyl-tofacitinib is an impurity compound of Tofacitinib(C781351). Tofacitinib is a Janus kinase inhibitor for the treatment of rheumatoid arthritis.<br>References Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979), Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993), Changelian, P., et al.: Science, 302, 875 (2003), Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003), Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007),<br></p>Fórmula:C18H25N5O3Forma y color:NeatPeso molecular:359.423(R)-N-Desacryloyl N-3-Chloropropionyl Ibrutinib
CAS:<p>Applications (R)-N-Desacryloyl N-3-Propionyl Ibrutinib is an impurity of Ibrutinib (I124970), which is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)<br></p>Fórmula:C25H25ClN6O2Forma y color:NeatPeso molecular:476.958N’-Cyano-N,N-dimethylguanidine
CAS:Producto controlado<p>Impurity Cimetidine EP Impurity G<br>Applications N-Cyano-N',N''-dimethylguanidine (Cimetidine EP Impurity G) is an impurity of Cimetidine (C441650), which acts as a competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output (1).<br>References 1. Brimblecombe, R. et al.: J. Int. Med. Res. 1975 Mar:3(2) 86-92<br></p>Fórmula:C4H8N4Forma y color:NeatPeso molecular:112.13Brivaracetam-d7
CAS:Producto controlado<p>Applications Brivaracetam-d7, is the labeled analogue of Brivaracetam (B677645), which is a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.<br>References Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007);<br></p>Fórmula:C11H13D7N2O2Forma y color:Off White SolidPeso molecular:219.331-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:309.32101440429695-Hydroxy Dantrolene
CAS:Producto controladoFórmula:C14H10N4O6Forma y color:YellowPeso molecular:330.254,5-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718758-Chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]-diazepin-11-one
CAS:Producto controlado<p>Impurity CLOZAPINE EP IMPURITY A<br>Stability Store in Freezer<br>Applications A useful intermediate for the preparation of pharmaceutical actives and fine chemicals. Antipsychotic drug.<br>References Venkat Rao, S., Arab. J. Chem., 13, 6040 (2020)<br></p>Fórmula:C13H9ClN2OForma y color:NeatPeso molecular:244.684'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic Acid
CAS:Producto controlado<p>Impurity Telmisartan Bromo Acid Impurity<br>Applications An impurity of Telmisartan (D294250). An intermediate in the preparation of antihypertensive agents.<br>References Sharma, M.C. et al.: Adv. Appl. Sci, Res., 1, 120 (2010); Sharma, M.C. et al.: Int. J. Adv. Pharmac. Sci., 1, 249 (2010);<br></p>Fórmula:C14H11BrO2Forma y color:NeatPeso molecular:291.14O3-Desethyl Apremilast
CAS:Producto controladoFórmula:C20H20N2O7SForma y color:NeatPeso molecular:432.45
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