Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65578 productos de "Derivados de Quinazolina y Quinolina"
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Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Fórmula:C9H15NO3SForma y color:White To Off-WhitePeso molecular:217.28N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester
CAS:Producto controlado<p>Applications N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester is an impurity of the drug Valsartan (V095750), which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C25H30N2O3Forma y color:Colourless OilyPeso molecular:406.52L-Aminobutyric Acid
CAS:<p>Applications Receptor antagonist.<br>References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995),<br></p>Fórmula:C4H9NO2Forma y color:NeatPeso molecular:103.12Ketanserin Tartrate
CAS:Producto controlado<p>Applications Ketanserin Tartrate is used in nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis for preventing a variety of diseases ranging from cancer to ischemic injury.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gohil, V. M., et al.: Nat. Biotechnol, 28, 249 (2010)<br></p>Fórmula:C22H22FN3O3·C4H6O6Forma y color:Off-WhitePeso molecular:545.51Norfloxacin-d5
CAS:Producto controlado<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Fórmula:C162H5H13FN3O3Forma y color:NeatPeso molecular:324.363,3'-(5'-(3-(Pyridin-3-yl)phenyl)-[1,1':3',1''-terphenyl]-3,3''-diyl)dipyridine
CAS:Pureza:97%Peso molecular:537.6660156253-[(pyridin-3-ylamino)carbonyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid
CAS:Pureza:95.0%Peso molecular:258.2770080566406Prochlorperazine
CAS:Producto controlado<p>Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.<br>References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),<br></p>Fórmula:C20H24ClN3SForma y color:YellowPeso molecular:373.943-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:318.85998535156254-Phenyl-2-(4-pyridyl)thiazole-5-carboxylic acid
CAS:Forma y color:SolidPeso molecular:282.320007324218752,6-Dichloro-4-phenyl-quinazoline
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:275.1300048828125Benzyl (3-fluoro-4-morpholinophenyl)carbamate
CAS:Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:330.35900878906254-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C15H17N3O2SForma y color:White To Light YellowPeso molecular:303.38Sibutramine, Hydrochloride Monohydrate
CAS:Producto controladoFórmula:C17H26ClN·ClH·H2OForma y color:Off White SolidPeso molecular:334.32(Quinolin-2-ylsulfanyl)-acetic acid
CAS:Fórmula:C11H9NO2SPureza:97%Forma y color:SolidPeso molecular:219.263-(4-Bromophenyl)-1-phenyl-1H-pyrazole-4-carboxaldehyde
CAS:Pureza:95.0%Peso molecular:327.18099975585944-ethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.3699951171875PD 169,316
CAS:<p>M02298 - PD 169,316</p>Fórmula:C20H13FN4O2Pureza:>98%Forma y color:SolidPeso molecular:360.34799194335945-Imino-N,4-bis(4-phenyl)-4,5-dihydro Riluzole
Producto controladoFórmula:C16H10F6N4O2SForma y color:NeatPeso molecular:436.333-(2,6-Dimethylmorpholino)-1,1,1-trifluoro-2-propanol
CAS:Fórmula:C9H16F3NO2Forma y color:SolidPeso molecular:227.227(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
CAS:Pureza:97%Forma y color:SolidPeso molecular:428.513-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Forma y color:NeatPeso molecular:252.276-nitro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:286.309997558593753-(2-Methoxyphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS:Pureza:98%Peso molecular:294.30999755859375Everolimus
CAS:Producto controlado<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C53H83NO14Pureza:~90%Forma y color:NeatPeso molecular:958.222-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Fórmula:C13H11NOSForma y color:Grey To BrownPeso molecular:229.30N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Producto controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Forma y color:NeatPeso molecular:425.433-(4-((1H-IMIDAZOL-1-YL)METHYL)PHENYL)-N-(TERT-BUTYL)THIOPHENE-2-SULFONAMIDE
CAS:Pureza:95.0%Peso molecular:375.510009765625Blonanserin-d5
CAS:Producto controlado<p>Applications Labelled Blonanserin (B595850). A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.<br>References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),<br></p>Fórmula:C23H25D5FN3Forma y color:NeatPeso molecular:372.53(S)-3-((tert-Butoxycarbonyl)amino)-4-(thiophen-2-yl)butanoic acid
CAS:Pureza:96%Peso molecular:285.3599853515625TERT-BUTYL 3-(THIOPHEN-2-YL)PYRROLIDINE-1-CARBOXYLATE
CAS:Pureza:95.0%Peso molecular:253.36000061035156Ref: 10-F530586
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar(5-amino-1-phenyl-1H-pyrazol-4-yl)(1H-indol-3-yl)methanone
CAS:Pureza:95.0%Peso molecular:302.33700561523442-(1-Methyl-1H-pyrazol-3-yl)-quinoline-4-carboxylic acid
CAS:Forma y color:SolidPeso molecular:253.261001586914065-(4-METHYLPYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE
CAS:Pureza:90.0%Peso molecular:210.240005493164062,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Producto controlado<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Fórmula:C13H14F3N3OForma y color:NeatPeso molecular:285.264,6-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.3699951171875N4-(4-Fluorophenyl)-7-methoxyquinazoline-4,6-diamine (Dacomitinib Impurity)
CAS:Pureza:97%Forma y color:SolidPeso molecular:284.2941,5-Dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:167.16400146484375Lansoprazole Sulfone
CAS:<p>Impurity Lansoprazole USP Related Compound A<br>Applications A metabolite of Lansoprazole, as gastric pump inhibitor. Lansoprazole USP Related Compound A.<br>References De Morais, S., et al.: Mol. Pharmacol., 46, 594 (1994), Spencer, C., et al.: Drugs, 48, 404 (1994), Pearce, R., et al.: J. Pharmacol. Exp. Ther., 277, 805 (1996), Tassaneeyakul, W., et al.: Br. J. Clin. Pharmacol., 49, 139 (2000),<br></p>Fórmula:C16H14F3N3O3SForma y color:NeatPeso molecular:385.36Diminazene-13C2,15N4 Dihydrochloride (major)
CAS:<p>Applications Labelled Diminazene (D479550). Antiprotozoal (Trypanosoma, Babesia).<br>References Braithwaite, A.W.<br></p>Fórmula:C1213C2H17Cl2N315N4Forma y color:Yellow To Dark YellowPeso molecular:360.2Dolutegravir Sodium
CAS:<p>Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)<br></p>Fórmula:C20H18F2N3O5·NaForma y color:NeatPeso molecular:441.36Levofloxacin-d3 Sodium Salt
CAS:Producto controlado<p>Applications Levofloxacin-d3 Sodium Salt, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Fórmula:C18H16D3FN3NaO4Forma y color:NeatPeso molecular:386.374-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:<p>Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C21H16Cl2N2O3Forma y color:NeatPeso molecular:415.272-(2-Chloro-phenoxymethyl)-2 H -pyrazole-3-carboxylic acid
CAS:Fórmula:C11H9ClN2O3Forma y color:SolidPeso molecular:252.655-(2,6-Dichloropyridin-4-yl)-4-methyl-4H-1,2,4-triazole-3-thiol
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:259.969022552Argatroban
CAS:<p>Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.</p>Fórmula:C23H36N6O5SPureza:99.77% - >99.99%Forma y color:White To Off-White Crystalline SolidPeso molecular:508.631,3-Bis[(3-(3-methyl-2-pyridin-2-yl)-1,2,4-oxadiazol)-5-yl]benzene
CAS:Pureza:97%Peso molecular:396.41000366210942-(2,5-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:288.3599853515625N-Mesyldronedarone
CAS:Producto controlado<p>Applications N-Mesyldronedarone is an impurity of Dronedarone (D679445, HCl); a drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009); Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009); Mahender, M., et al.: Org. Process Res. Dev., 18, 157 (2014)<br></p>Fórmula:C32H46N2O7S2Forma y color:NeatPeso molecular:634.854-(Benzo[d]thiazol-2-ylthio)morpholine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:252.350006103515623,5-Dimethyl-1H-pyrazole-4-sulfonyl chloride hydrochloride
CAS:Fórmula:C5H8Cl2N2O2SPureza:97%Forma y color:SolidPeso molecular:231.09Picloram
CAS:<p>Picloram (Tordon) is an auxin-type herbicide with carcinogenic properties, controlling herbaceous weeds and woody plants.</p>Fórmula:C6H3Cl3N2O2Pureza:99.74%Forma y color:White Powder Physical Description Fine Beige Crystals Or White Powder Odor Of Chlorine (Ntp 1992)Peso molecular:241.46(S)-(-)-Pantoprazole Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications The S-enantiomer of Pantoprazole (P183000).<br>References Simon, W.A., et al.: Biochem. Pharmacol., 39, 1799 (1990),<br></p>Fórmula:C16H14F2N3O4S·NaForma y color:NeatPeso molecular:405.35(2E)-3-[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]-N-(pyridin-3-ylmethyl)prop-2-enamide
CAS:Peso molecular:398.44100952148442-(thiophen-2-yl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
CAS:Pureza:95.0%Peso molecular:230.3300018310547Cimetidine Amide Dihydrochloride
CAS:Producto controlado<p>Impurity Cimetidine EP Impurity C<br>Applications Cimetidine Amide Dihydrochloride (Cimetidine EP Impurity C) is an impurity of Cimetidine.<br>References Durant, G.J., et al.: J. Med. Chem., 18, 830 (1975), Pounder, R.E., et al.: Br. Med. J., 2, 307 (1975),<br></p>Fórmula:C10H18N6OS·2ClHForma y color:White To Off-WhitePeso molecular:343.281-Phenyl-3-(5,6,7,8-tetrahydronaphthalen-2-yl)-1h-pyrazol-5-amine
CAS:Pureza:97%Peso molecular:289.38198852539065-(1,3-Dioxolan-2-yl)-2-(4-isopropylbenzoyl)thiophene
CAS:Pureza:97.0%Peso molecular:302.39001464843753-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS:Fórmula:C11H15BClNO2Pureza:98%Peso molecular:239.512-(4-aminophenyl)-3-pyridinol dihydrochloride
CAS:Fórmula:C11H12Cl2N2OPureza:95.0%Forma y color:SolidPeso molecular:259.131-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:309.32101440429694-(4-Phenylbutoxy)benzoic Acid
CAS:Producto controlado<p>Applications 4-(4-PHENYLBUTOXY)BENZOIC ACID (cas# 30131-16-9) is a useful research chemical.<br></p>Fórmula:C17H18O3Forma y color:NeatPeso molecular:270.322-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
CAS:Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:361.26998901367192-Chloro-4-(dibenzo[b,d]furan-3-yl)-6-phenyl-1,3,5-triazine
CAS:Pureza:98%Peso molecular:357.79998779296875Hydroxy Dehydro Nifedipine Lactone
CAS:Producto controladoFórmula:C16H12N2O6Forma y color:NeatPeso molecular:328.284-Methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS:Fórmula:C7H6N2O2Pureza:97%Forma y color:SolidPeso molecular:150.1371-[3-(Trifluoromethyl)pyrid-2-yl]piperazine
CAS:Fórmula:C10H12F3N3Pureza:98%Forma y color:Solid, Low Melting SolidPeso molecular:231.222(3R,4S)-3-[(3S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-2-one
CAS:Producto controlado<p>Applications Labelled Ezetimibe (E975000), an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Fórmula:C242H4H17F2NO3Forma y color:NeatPeso molecular:413.45
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