Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65624 productos de "Derivados de Quinazolina y Quinolina"
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(E)-Naftifine
CAS:<p>Applications (E)-Naftifine is an intermediate in synthesizing Naftifine N-Oxide (N213110), which is an impurity or metabolite of Naftifine Hydrochloride (N213100), an allylamine antifungal agent.<br>References Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004)<br></p>Fórmula:C21H21NForma y color:NeatPeso molecular:287.406-Oxo-(S,S)-Palonosetron (~90%)
CAS:Producto controlado<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Fórmula:C19H22N2O2Pureza:~90%Forma y color:NeatPeso molecular:310.393-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine
CAS:Producto controlado<p>Impurity Nimodipine EP Impurity B<br>Applications 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).<br>References Avalani, J. R., et al.: J. Chem. Sci., 124, 1091-1096 (2012); Barmpalexis, P., et al.: J. Pharmaceut. Biomed., 49, 1192-1202 (2009)<br></p>Fórmula:C21H26N2O6Forma y color:NeatPeso molecular:402.444’-Bromomethylbiphenyl-2-carboxylic Acid, Methyl Ester
CAS:Producto controladoFórmula:C15H13BrO2Forma y color:NeatPeso molecular:305.173-Methylxanthine
CAS:Producto controlado<p>Impurity Pentoxifylline EP Impurity B<br>Applications 3-Methylxanthine (Pentoxifylline EP Impurity B) is a metabolite of Theophylline (58-55-9), which is a Xanthine (X499950) derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine.They can also act as Bronchodilator.<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975); Svedmyr, K., et al.: Allergy, 37, 111 (1982);<br></p>Fórmula:C6H6N4O2Forma y color:BeigePeso molecular:166.14Tavaborole (>90%)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tavaborole is a topical treatment of toenail onychomycosis.<br>References Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)<br></p>Fórmula:C7H6BFO2Pureza:>90%Forma y color:NeatPeso molecular:151.93Ambrisentan-d10
CAS:Producto controlado<p>Applications Ambrisentan-d10, is the labeled analogue of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H12D10N2O4Forma y color:NeatPeso molecular:388.483-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CAS:Producto controlado<p>Stability Air Sensitive<br>Applications 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine is used in the preparation of c-Src and Abl inhibitors based on the scaffold present in Imatinib (G407000), used in the treatment of myelogenic leukemia. It is a COVID19-related research product.<br>References Seeliger, M. et al.: Canc. Res., 69, 2384 (2009); Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)<br></p>Fórmula:C11H10N3F3Forma y color:NeatPeso molecular:241.21Cinitapride
CAS:<p>Applications A novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors (1,2,3).<br>References (1) Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997)(2) Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007)(3) Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Fórmula:C21H30N4O4Forma y color:NeatPeso molecular:402.49Nilotinib 3-Imidazolyl N-oxide
CAS:Producto controlado<p>Applications 4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Fórmula:C28H22F3N7O2Forma y color:NeatPeso molecular:545.52Benzo[b]thien-2-yl Ketone (Zileuton Impurity)
CAS:Producto controlado<p>Applications Benzo[b]thien-2-yl ketone is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs).<br>References Israel, E., et al.: JAMA, 275, 931 (1996); Mahboobi, S., et al.: J. Med. Chem., 45, 1002 (2002); Mitschke, U. & Bäuerle, P.: J. Chem. Soc. Perk. Trans., 1, 740 (2001); Nenajdenko, V., et al.: Russ. Chem. Bull., 61, 1456 (2012)<br></p>Fórmula:C17H10OS2Forma y color:NeatPeso molecular:294.39Gabapentin Ethyl Ester Hydrochloride
CAS:Producto controlado<p>Applications Protected Gabapentin (G117250). Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C11H21NO2·ClHForma y color:NeatPeso molecular:235.75DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate
CAS:Producto controlado<p>Applications DL-threo-Droxidopa-d3 Hydrochloride Salt Hydrate is an isotope labeled compound of DL-threo-Droxidopa (D689950), a synthetic amino acid precursor of Norepinephrine. An Antiparkinson.<br>References Bartholini, J., et al.: J. Pharmacol. Exp. Ther ., 193, 523 (1975), Kato, T., et al.: Biochem. Pharmacol., 36, 3051 (1987), Kawabata, A., et al.: Br J. Pharmacol., 111, 503 (1994)<br></p>Fórmula:C9H8D3NO5•HCl•x(H2O)Forma y color:NeatPeso molecular:216.2136461802(Z)-4-(2,4-Difluorobenzoyl)piperidine Oxime
CAS:Producto controlado<p>Applications Intermediate in the preparation of Risperidone (R525000) and it’s derivatives.<br></p>Fórmula:C12H14F2N2OForma y color:NeatPeso molecular:240.2492N,N-Bis[2-(2-hydroxyethoxy)ethyl] Quetiapine Chloride
Producto controladoFórmula:C25H34ClN3O4SForma y color:NeatPeso molecular:508.073-Ethynylaniline
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications Reagent in the preparation of a metabolite of Erlotinib (E625000).<br></p>Fórmula:C8H7NForma y color:Colourless To Dark RedPeso molecular:117.15S-(+)-Atomoxetine Hydrochloride
CAS:Producto controlado<p>Impurity Atomoxetine EP Impurity B<br>Applications ent S-(+)-Atomoxetine Hydrochloride (Atomoxetine EP Impurity B) is an enatiomer of Atomoxetine, a Norepinephrine uptake blocker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Robertson, D., et al.: J. Med. Chem., 31, 1412 (1988), Hwamg, et al.: Neurosci. Lett., 265, 151 (1999),<br></p>Fórmula:C17H21NO·ClHForma y color:NeatPeso molecular:291.82Ambroxol Cycloimine Impurity
CAS:Producto controlado<p>Applications 4-(6,8-Dibromo-3(4H)-quinazolinyl)-cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C14H16Br2N2OForma y color:NeatPeso molecular:388.09762',6'-Dichloroacetanilide
CAS:Producto controladoFórmula:C8H7Cl2NOForma y color:NeatPeso molecular:204.05Dehydro Silodosin
CAS:Producto controlado<p>Applications Dehydro Silodosin is an impurity of Silodosin (S465000).<br>References Moriyama., et al.: Eur. J. Pharmacol., 331, 39 (1997), Zhu, J., et al.: Br. J. Pharmacol., 131, 546 (2000),<br></p>Fórmula:C25H30F3N3O4Forma y color:NeatPeso molecular:493.522-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
CAS:<p>Applications 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug.<br>References Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006),<br></p>Fórmula:C20H23FN6O6Forma y color:Off-WhitePeso molecular:462.437-Hydroxyquinoline-(1H)-2-one
CAS:Producto controladoFórmula:C9H7NO2Forma y color:NeatPeso molecular:161.16Hydroxymethyl Dasatinib
CAS:Producto controlado<p>Applications An oxidative metabolite of Dasatinib (M24 metabolite); used in the treatment of cancers and immune diseases. It is a COVID19-related research product.<br>References Jaworski, T., et al.: Xenobiotica, 21, 1451 (1991), Shah, N., et al.: Science, 305, 399 (2004), O'Hare, T., et al.: Cancer Res., 65, 4500 (2005), Das, J., et al.: J. Med. Chem., 49, 6819 (2006), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008),<br></p>Fórmula:C22H26ClN7O3SForma y color:NeatPeso molecular:504.005-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS:Producto controlado<p>Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).<br>References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);<br></p>Fórmula:C14H11F3O5Forma y color:NeatPeso molecular:316.23Chlorpromazine-d6 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Chlorpromazine (C424750). Used as an antiemetic; antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990),<br></p>Fórmula:C172H6H13ClN2S·ClHForma y color:White To Light YellowPeso molecular:361.363’-[4-(5-Chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]propyl Domperidine (Domperidine Impurity F)
CAS:Producto controlado<p>Impurity Domperidone EP Impurity F<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100(P)), which is a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Fórmula:C37H42Cl2N8O3Forma y color:NeatPeso molecular:717.69Montelukast Cyclized Ether impurity
CAS:Producto controlado<p>Applications A cyclic ether impurity of antiasthmatic Montelukast (M568000).<br>References Egekeze, J.O. et al.: Anal. Chem., 67, 2292 (1995);<br></p>Fórmula:C29H26ClNOForma y color:NeatPeso molecular:439.98N’-[2-[2,4-(Dimethylphenyl)thio]phenyl] Vortioxetine
Producto controlado<p>Applications N’-[2-[2,4-Dimethylphenyl)thio]phenyl] Vortioxetine is an impurity of Vortioxetine (V766000, HBr salt) which is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.<br>References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Fórmula:C32H34N2S2Forma y color:NeatPeso molecular:510.76Loxapine N-Glucuronide Chloride
CAS:Producto controladoFórmula:C24H27ClN3O7·ClForma y color:NeatPeso molecular:540.3934,6-Dichloro-5-nitro-2-(propylthio)pyrimidine
CAS:<p>Stability Unstable in DMSO Solution<br>Applications 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is used as a reactnat in the synthesis of carba-nucleosides as potent antagonists of ADP purinergic receptor P2Y12 on human platelets.<br>References Ye, H., et al.: ChemMedChem, 3, 732 (2008);<br></p>Fórmula:C7H7Cl2N3O2SForma y color:NeatPeso molecular:268.1203-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione
CAS:<p>3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is a research and development impurity standard. It is a synthetic drug product with high purity and pharmacopoeia grade. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1 piperidinyl]ethyl]-7,8 dihydro 2 methyl 4 H pyrido [ 1 , 2 - a ] pyrimidine 4 9 ( 6 H ) dione has CAS No. 118951665 1 and is an analytical standard for HPLC analysis. 3-[2-[4-(6 Fluoro 1 , 2 benzisox</p>Fórmula:C23H25FN4O3Pureza:Min. 95%Peso molecular:424.47 g/molrac-Norphenylephrine hydrochloride
CAS:Producto controlado<p>Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).</p>Fórmula:C8H12ClNO2Pureza:Min. 95%Peso molecular:189.64 g/molDeiodo amiodarone
CAS:<p>Deiodo amiodarone is a noncompetitive inhibitor that binds to the active site of the enzyme and blocks the binding of substrate, thereby inhibiting the synthesis of catecholamines. Deiodo amiodarone has been shown to inhibit the oxidation of benzofuran derivatives in rat liver microsomes, human liver tissue samples, and chromatographic conditions. The inhibition constant for deiodo amiodarone was determined by liquid chromatography with a homogenizing technique.</p>Fórmula:C25H30INO3Pureza:Min. 95%Peso molecular:519.42 g/mol2-Methyl-3,4-dimethoxy pyridine hydrochloride
CAS:<p>2-Methyl-3,4-dimethoxy pyridine hydrochloride is an analytical standard that is used as a reference compound in the pharmaceutical industry to identify impurities in drug products. It also has a niche use as an API impurity and HPLC standard. 2-Methyl-3,4-dimethoxy pyridine hydrochloride is used as an intermediate for the synthesis of other drugs, including benzodiazepines and beta blockers. It is also used in research and development for its high purity. This chemical is natural or synthetic in origin but can be custom synthesized to meet specific requirements. 2-Methyl-3,4-dimethoxy pyridine hydrochloride also has CAS number 1210824-88-6.</p>Fórmula:C8H11NO2HClPureza:Min. 95%Peso molecular:189.64 g/mol4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid
CAS:<p>4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid is an analytical reagent that is used in research and development as a drug product impurity standard. This compound has been shown to be metabolized by cytochrome P450 1A1 and 2C8 to form 4-hydroxybenzoic acid and 4,4''-[(4'-methyl-2' propyl-[2,6']bi-1H-benzimidazol-1,1' diyl)bis(methylene)]bis[3-(4-hydroxyphenyl)-propionic acid], respectively. 4',4''-[(4'-Methyl-2' propyl-[2,6']bi-1</p>Fórmula:C46H38N4O4Pureza:Min. 95%Peso molecular:710.82 g/mol(R)-Pramipexole 2HCl
CAS:Producto controlado<p>Dopamine (D2 and D3) receptor agonist; has anti-parkinsonian effects</p>Fórmula:C10H19Cl2N3SPureza:Min. 95%Peso molecular:283.06767Alverine EP Impurity C
CAS:<p>Alverine EP Impurity C is a by-product of the synthesis of alverine, which is an ammonium salt. The process involves the use of high yield, high purity triflic acid, and organic solvents. The reaction system is typically carried out in a solvent such as toluene or dichloromethane. The organic solvent is then removed by filtration and the desired product can be obtained by crystallization or recrystallization. Alverine EP Impurity C has been shown to have insecticidal properties when applied externally, due to its interaction with insect stereoisomers. It also has anticancer activity and may be used in cancer therapy treatments that involve decompressing tumours and increasing blood supply to the area. Alverine EP Impurity C also has a citric acid binding property that makes it insoluble in water.</p>Fórmula:C11H17NPureza:Min. 95%Peso molecular:163.26 g/molDasatinib impurity
CAS:<p>Dasatinib is a cancer drug that is used to treat patients with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. It inhibits the activity of tyrosine kinases, in particular Bcr-Abl and Src. Dasatinib is a structural analog of imatinib, which has been shown to be effective against chronic myeloid leukemia by inhibiting the activity of Bcr-Abl. Dasatinib impurity is an unwanted substance found in dasatinib. It can be synthesized from formic acid, chloride and chlorine using a series of industrial processes. The salt form of dasatinib impurity is acidic and synthetic.</p>Fórmula:C22H27N7O2SPureza:Min. 95%Peso molecular:453.56 g/molAlverine EP Impurity D
<p>Alverine EP Impurity D is a synthetic impurity that is the result of the synthesis of Alverine EP. It is a metabolite that can be found in blood plasma and urine. This substance has been shown to have pharmacological activity, but its exact function is unknown. It is not present in natural sources and it does not have pharmacopoeia listing. Alverine EP Impurity D has been detected by HPLC analysis.END></p>Fórmula:C20H33NPureza:Min. 95%Peso molecular:287.48 g/mol4-Hydoxymethyl-5-methylimidazol
CAS:<p>4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.</p>Fórmula:C5H8N2OPureza:Min. 95%Peso molecular:112.13 g/molBrexpiprazole impurity 10
CAS:<p>Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.</p>Fórmula:C16H15NO2Pureza:Min. 95%Peso molecular:253.3 g/mol6-Amino-5-ethyl-5-phenyl-2,4(3H,5H)-pyrimidinedione
CAS:<p>Phenobarbital impurity B is an analytical reference material that is available as a HPLC standard and a CAS No. 58042-96-9. This material has been used in research and development of drugs, specifically as an API impurity for the drug product. Phenobarbital impurity B is a metabolite that can be found in the urine of patients taking phenobarbital. It has shown to have pharmacopoeia standards. Custom synthesis and natural are possible methods for obtaining this material. Synthetic is the most common method for generating this substance.</p>Fórmula:C12H13N3O2Pureza:Min. 95%Peso molecular:231.25 g/molSolifenacin Impurity D
CAS:<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>Fórmula:C31H28N2OPureza:Min. 96 Area-%Forma y color:White PowderPeso molecular:444.57 g/mol3-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>3-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one is a synthetic compound that functions as a drug product. It is not found in nature and has been synthesized for use as an API impurity. The CAS number for this compound is 1005191-81-0. 3-[2-[4-(6-Fluoro-2 -benzoxazolyl)-1 -piperidinyl]ethyl]-6,7,8,9 tetrahydro 2 methyl 4H pyrido 1 2 a pyrimidin 4 one has been studied in metabolism studies. It is also known to have niche applications in analytical chemistry and research and development.</p>Fórmula:C23H27FN4O2Pureza:Min. 95%Peso molecular:410.48 g/mol3-(Dimethylamino)-1-(2-thienyl)propan-1-ol
CAS:<p>3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is an organic compound that is used as a chiral building block in the synthesis of drugs. It is not currently used in any known drug, but it has been shown to be racemized at high temperatures. 3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is also a byproduct of pollution and can be found in the environment where it may be degraded by bacteria.</p>Fórmula:C9H15NOSPureza:Min. 95%Peso molecular:185.29 g/mol3-[2-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>Roflumilast is a drug used to treat chronic obstructive pulmonary disease. It is also used to treat inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Roflumilast inhibits the enzyme cytochrome P450 in the liver, which is responsible for metabolizing certain drugs and other substances. This inhibition reduces the metabolism of these substances, leading to increased levels of these substances in the body. This can lead to side effects such as nausea, vomiting, dizziness, headache, and itching. Roflumilast also has an anti-inflammatory effect on the intestines by regulating the production of inflammatory cytokines and inhibiting the activity of pro-inflammatory enzymes.</p>Fórmula:C23H27F2N3O2Pureza:Min. 95%Peso molecular:415.48 g/molrac-Des(isopropylamino) acebutolol diol
CAS:<p>rac-Des(isopropylamino) acebutolol diol is a synthetic drug substance that is used for research and development purposes. It has a purity of 99% or greater, does not contain any impurities, and is manufactured using the latest technology. The rac-Des(isopropylamino) acebutolol diol is a pharmaceutical grade product with high purity and quality standards that have been verified by HPLC analysis. This compound is an analytical standard that can be used to calibrate mass spectrometry instruments. Rac-Des(isopropylamino) acebutolol diol is also metabolized into the natural metabolite noracebutanol by cytochrome P450 enzymes in humans.</p>Fórmula:C15H21NO5Pureza:Min. 95%Peso molecular:295.33 g/mol(3S,4S,3’S)-Ezetimibe
CAS:<p>Please enquire for more information about (3S,4S,3’S)-Ezetimibe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C24H21F2NO3Pureza:Min. 95%Peso molecular:409.43 g/molN2-Methyl alfuzosin hydrochloride (1:1)
CAS:<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>Fórmula:C19H28ClN5O4Pureza:Min. 95%Peso molecular:425.91 g/molN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride
CAS:<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.</p>Fórmula:C14H22ClN5O2Pureza:Min. 95%Peso molecular:327.81 g/molChloromethyl olanzapinium chloride
CAS:<p>Chloromethyl olanzapinium chloride is an analytical reference material that can be used as a standard for HPLC-UV analysis. It is also used in the development of new drugs and as an impurity standard during drug manufacturing. Chloromethyl olanzapinium chloride has been shown to be a metabolite of Olanzapine, which is a niche drug product that is not commercially available. Chloromethyl olanzapinium chloride is listed by the USP, EP and JP as a drug product impurity. It can be synthesized from natural or synthetic sources.</p>Fórmula:C18H22Cl2N4SPureza:Min. 95%Forma y color:PowderPeso molecular:397.37 g/mol2-Deschloro aripiprazole
CAS:<p>2-Deschloro aripiprazole is a drug that belongs to the class of antipsychotics. It is an atypical antipsychotic with a high affinity for human albumin and α1-acid glycoprotein, which are plasma proteins. 2-Deschloro aripiprazole has been shown to interact with human albumin and α1-acid glycoprotein in vitro, and it has been suggested that this interaction may be responsible for its pharmacological effects. 2-Deschloro aripiprazole has also been shown to bind to the dopamine D2 receptor, which is thought to be responsible for its therapeutic effects as an antipsychotic. The molecular interactions between 2-deschloro aripiprazole and human albumin have been studied using isothermal titration calorimetry (ITC) and molecular docking studies. These studies have helped us understand how 2-deschloro aripiprazole binds to human album</p>Fórmula:C23H28ClN3O2Pureza:Min. 95%Peso molecular:413.94 g/mol(R,R)-Solifenacin succinate
CAS:<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>Fórmula:C23H26N2O2•C4H6O4Pureza:Min. 95%Forma y color:PowderPeso molecular:480.55 g/mol3-O-Desethyl-5-O-desmethyl amlodipine
CAS:<p>3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.</p>Fórmula:C17H19ClN2O5Pureza:Min. 95%Peso molecular:366.8 g/molThiamethoxam
CAS:<p>Thiamethoxam ((E)-thiamethoxam) is an insecticide of broad-spectrum neonicotinoids.</p>Fórmula:C8H10ClN5O3SPureza:>99.99%Forma y color:SolidPeso molecular:291.71Demethylpiperazinyl sildenafil sulfonic acid
CAS:<p>Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.</p>Fórmula:C17H20N4O5SPureza:Min. 95%Forma y color:PowderPeso molecular:392.43 g/molChlorhexidine EP Impurity N hydrochloride
CAS:<p>Chlorhexidine is an antimicrobial agent that has been shown to be effective against escherichia and chlorobenzene. It also has a low toxicity for humans and animals, as well as for the environment. Chlorhexidine EP Impurity N is a chlorhexidine impurity that is produced during the synthesis of chlorhexidine acetate. This impurity can be used in research to measure hydrogen peroxide levels, which can help determine the purity of chlorhexidine acetate. Recoveries of this compound were found to be high in human dental plaque and pneumococcus bacteria. Average recoveries were found to be higher when measured by ultraviolet spectroscopy than by gas chromatography-mass spectroscopy (GC-MS).</p>Fórmula:C15H25ClN8•(HCl)xPureza:Min. 95%Peso molecular:352.87 g/molIcotinib Hydrochloride
CAS:<p>Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.</p>Fórmula:C22H22ClN3O4Pureza:99.89%Forma y color:SolidPeso molecular:427.88Di-destriazole anastrozole dimer impurity
CAS:<p>Di-destriazole anastrozole dimer impurity is a synthetic impurity that is created during the synthesis of anastrozole. It has been studied as a possible metabolite of the drug, but its role in metabolism is not well understood. Di-destriazole anastrozole dimer impurity is soluble in water and methanol and has a melting point of between 1°C to 2°C. The purity of this compound is typically at least 99% with a specific gravity of 1.043 g/mL.</p>Fórmula:C26H29N3Pureza:Min. 95%Peso molecular:383.53 g/mol4-Oxo valsartan benzyl ester
CAS:<p>4-Oxo valsartan benzyl ester is a drug product that is used for research and development purposes. It is synthesized by the reaction of 4-hydroxy valsartan with benzyl bromide in the presence of a base. 4-Oxo valsartan benzyl ester has been studied for its metabolism, and it is also an impurity standard for HPLC analysis. The purity of this compound is >98% and it has CAS number 188240-32-6.</p>Fórmula:C31H33N5O4Pureza:Min. 95%Peso molecular:539.63 g/mol1,3-bis(1,1-Dimethylpropyl) benzene
CAS:<p>1,3-bis(1,1-Dimethylpropyl) benzene is a synthetic compound that is used in drug product formulation. It is also used as an analytical standard for the determination of 1,3-bis(1,1-dimethylethyl)benzene in drug products and as a natural impurity in API preparations. This compound is metabolized to 1,3-dibromobenzene and 1,2-dibromoethane during its metabolic process. The chemical properties of this compound are similar to those of other alkylbenzenes and it has been shown to have pharmacological effects such as analgesic and antiinflammatory activities.</p>Fórmula:C16H26Pureza:Min. 95%Peso molecular:218.38 g/molTrazodone Hydrochloride BP Impurity A
CAS:<p>Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.</p>Fórmula:C19H22CIN5O2Pureza:Min. 95%Peso molecular:491.33 g/molChlorhexidine diacetate impurity A
CAS:<p>Chlorhexidine diacetate impurity A is a high purity, analytical standard for the detection of chlorhexidine diacetate impurities in drug products. Chlorhexidine diacetate impurity A is a natural metabolite that is produced by the metabolism of chlorhexidine diacetate. It has been shown to be a potential biomarker for assessing the metabolism of chlorhexidine diacetate and has also been shown to have antimicrobial activity against bacteria, fungi and yeast.</p>Fórmula:C16H24ClN9Pureza:Min. 95%Forma y color:White to off-white solid.Peso molecular:377.88 g/molIndoxacarb impurity 6
CAS:<p>Indoxacarb is a racemic compound that is used as an insecticide. It belongs to the class of carbamate insecticides and is marketed under the trade name of "Provaunt". Indoxacarb inhibits acetylcholinesterase, which leads to increased acetylcholine in the synapse, resulting in death. The production of indoxacarb has been optimized to yield a high-level of stereoselectivity. This optimization was achieved through a biocatalytic process that uses a strain of Escherichia coli with high stereoselectivity. This strain produces indoxacarb with a high level of stereoselectivity, which can be confirmed by NMR analysis.</p>Fórmula:C11H9ClO4Pureza:Min. 95%Forma y color:PowderPeso molecular:240.64 g/molSolifenacin N-oxide
CAS:<p>Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.</p>Fórmula:C23H26N2O3Pureza:Min. 95%Forma y color:White PowderPeso molecular:378.46 g/molApixaban Impurity 11
CAS:<p>Apixaban impurity 11 is an analytical standard used in research and development, drug development, and the production of API. It has a purity of 99.5% by HPLC and is a metabolite of apixaban. Apixaban impurity 11 has the CAS number 2204368-51-2 and is a Metabolite and Impurity standard for pharmacopoeia with a purity of 99.5% by HPLC. This product can be custom synthesized or natural with a purity of 99.5% by HPLC.</p>Fórmula:C29H31N5O5Pureza:Min. 95%Peso molecular:529.59 g/molLosartan isomer impurity, potassium salt
CAS:Producto controlado<p>Losartan is an angiotensin II receptor antagonist. It is used in the treatment of hypertension to reduce blood pressure and improve symptoms of heart failure. Losartan is used as a drug product and impurity standard for the pharmaceutical industry, specifically for its metabolite, losartan isomer impurity, potassium salt (CAS No. 860644-28-6). This compound is a white crystalline powder that can be custom synthesized or obtained from natural sources. High purity Losartan Isomer Impurity, Potassium Salt (CAS No. 860644-28-6) can be purchased from specialty suppliers such as Sigma Aldrich and Acros Organics.</p>Fórmula:C22H22ClKN6OPureza:Min. 95%Peso molecular:461 g/molBrexpiprazole impurity 3
CAS:<p>Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.</p>Fórmula:C25H27N3O3SPureza:Min. 95%Peso molecular:449.57 g/molLevofloxacin diamine impurity
CAS:<p>Levofloxacin is a synthetic fluoroquinolone antibiotic. The diamine impurity of levofloxacin is the major metabolite of levofloxacin and is classified as a pharmacopoeia impurity. Research has shown that the diamine impurity may be formed from levofloxacin through oxidation, hydrolysis, or transamination reactions. Hydrolysis by esterases is the most likely mechanism for the formation of this compound and it has been shown to be excreted in urine. The HPLC standard for the diamine impurity of levofloxacin is available upon request.</p>Pureza:Min. 95%1,4-Di-2-furoylpiperazine
CAS:<p>1,4-Di-2-furoylpiperazine is a synthetic compound that has been shown to have anti-inflammatory and analgesic properties. It was originally developed as a pharmaceutical drug candidate for the treatment of arthritis and other inflammatory disorders. 1,4-Di-2-furoylpiperazine is an impurity in the synthesis of the drug product diclofenac. The compound is also found as a metabolite in humans after oral administration of diclofenac. 1,4-Di-2-furoylpiperazine binds to protein and inhibits protein synthesis by preventing amino acid incorporation into proteins. It also has nicotinic effects on acetylcholine binding sites and can be used as an analytical standard for HPLC analysis of drugs containing this molecule.</p>Fórmula:C14H14N2O4Pureza:Min. 95%Peso molecular:274.27 g/molN-Methyl-N-(3-chloropropyl)homoveratrylamine
CAS:<p>N-Methyl-N-(3-chloropropyl)homoveratrylamine is a chlorinated alkylating agent that has been shown to accumulate in the myocardium. It is an anaesthetic that can be recycled and used as a nutrient. N-Methyl-N-(3-chloropropyl)homoveratrylamine binds to DNA, which blocks the synthesis of RNA and protein. This drug has been demonstrated to have antiarrhythmic effects, but it is not effective against cardiac arrhythmias caused by digitalis or hypoxia. N-Methyl-N-(3-chloropropyl)homoveratrylamine also has an antagonist effect on the central nervous system and may be useful for treating convulsions.</p>Fórmula:C12H19NO2·HClPureza:Min. 95%Peso molecular:245.75 g/molDes(oxopentyl) valsartan benzyl ester
CAS:<p>Des(oxopentyl) Valsartan Benzyl Ester is an analytical standard for the drug valsartan. It is a white to off-white, crystalline powder that is soluble in methanol and acetone. This compound can be used as an HPLC standard, or as an impurity standard in the development of valsartan drugs. Des(oxopentyl) Valsartan Benzyl Ester also has niche uses in natural product isolation and synthetic organic chemistry. It is a metabolite of des(oxopentyl)valsartan, which is a prodrug of valsartan.</p>Fórmula:C26H27N5O2Pureza:Min. 95%Peso molecular:441.53 g/mol9,10-Dioxo ketotifen
CAS:<p>9,10-Dioxo ketotifen is a drug product that belongs to the category of HPLC standards. It has been shown to be a metabolite of ketotifen and also an impurity in ketotifen. 9,10-Dioxo ketotifen has been shown to possess antihistamine activity and may have potential as a lead compound for the development of new drugs.</p>Fórmula:C19H17NO2SPureza:Min. 95%Forma y color:PowderPeso molecular:323.41 g/mol2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one
CAS:<p>2,12-Dihydro-1,3-dimethyl-9-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a synthetic compound that has not been evaluated in humans. This compound is an impurity standard for the synthesis of an API. The purity of this compound is >98% and it has been shown to be stable under acidic conditions.</p>Fórmula:C16H13N3O2SPureza:Min. 95%Peso molecular:311.36 g/mol(+/-)N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride
CAS:<p>N-Methyl-y-[3-(trifluoromethyl)-phenoxy]benzenepropanamine hydrochloride is a synthetic drug product that has been shown to be metabolized in humans. It is an impurity standard for HPLC and analytical methods. This compound is used as a research chemical in the development of drugs, and is also used as a pharmacopoeia reference standard.</p>Fórmula:C17H18F3NO·HClPureza:Min. 95%Peso molecular:345.79 g/mol(R)-7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7 H)-dione
CAS:<p>7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from</p>Fórmula:C33H30N8O4Pureza:Min. 95%Peso molecular:602.64 g/molMontelukast acyl-b-D-glucuronide acetic acid salt
CAS:<p>Metabolite of montelukast</p>Fórmula:C41H44ClNO9S·CH3CO2HPureza:Min. 95%Forma y color:Off-White PowderPeso molecular:822.36 g/molO-De(3-fluorobenzyl) lapatinib ditosylate
CAS:<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>Fórmula:C22H21ClN4O4S•(C7H8O3S)2Pureza:Min. 95%Peso molecular:817.35 g/mola,a'-[[[2-(3,4-Dimethoxyphenyl)ethyl]imino]di-3,1-propanediyl]bis[3,4-dimethoxy-α-(1-methylethyl)-benzeneacetonitrile
CAS:<p>2,3,4-Trimethoxybenzaldehyde is an organic compound that is used as a chemical intermediate in the synthesis of pharmaceuticals. It is also used as a reagent in the chemical industry and as a flavoring agent. 2,3,4-Trimethoxybenzaldehyde has been shown to be metabolized by human liver microsomes to yield metabolites that are not well characterized. The impurities found in this drug product are 2-methoxy-5-methylphenol and 2,6-dimethoxyphenol.</p>Fórmula:C42H57N3O6Pureza:Min. 95%Peso molecular:699.92 g/molN,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride
CAS:<p>N,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride is a synthetic compound that is metabolized to the natural product naphthol AS. It is an impurity in the drug product and can also be used as an analytical reference standard.</p>Fórmula:C25H38N2O4·2HClPureza:Min. 95%Peso molecular:503.5 g/mol2-[[2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione
CAS:<p>Please enquire for more information about 2-[[2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C22H19N3O6Pureza:Min. 95%Peso molecular:421.4 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid
CAS:<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>Fórmula:C14H11BrO2Pureza:Min. 95%Peso molecular:291.14 g/molErythromycin E
CAS:<p>Erythromycin E is a diluent that is used to make erythromycin solutions. It has been shown to have bioactive molecules by incubating it with chromatographic methods. These bioactive molecules are conjugates of erythromycin and methyl ethyl groups. Erythromycin E has also been shown to have genetic mechanisms, which may relate to its ability to inhibit the synthesis of inflammatory cytokines such as IL-1β and IL-8 in the airways. The acetate extraction method is used for the production of erythromycin E. This process involves extracting erythromycin from Streptomyces bacteria grown in an acetate buffer solution.</p>Fórmula:C37H65NO14Pureza:Min. 95%Forma y color:Off-White SolidPeso molecular:747.91 g/mol2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran
CAS:<p>2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is a benzofuran. It is a yellow solid that can be dissolved in water and alcohol.</p>Fórmula:C19H16I2O3Pureza:Min. 95%Peso molecular:546.14 g/mol3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:<p>3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is a research and development impurity standard. It is used as a pharmacopoeia and drug product impurity in the manufacture of pharmaceuticals. 3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H pyrido[1,2 a]pyrimidin 4 one is used in synthetic organic chemistry for the production of drugs. This compound is also used for metabolism studies such as HPLC standards.</p>Fórmula:C11H16N2OPureza:Min. 95%Peso molecular:192.26 g/mol[1,1'-Biphenyl]-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester
CAS:<p>Biphenyl-2'-(2H-tetrazol-5-yl)-4-carboxylic acid, [1,1'-biphenyl]-(2'-(2H-tetrazol-5-yl)-4-yl)methyl ester is a research and development impurity standard. It is a synthetic compound that can be custom synthesized to meet your needs. The product is available in high purity and pharmacopoeia grade. It has been used as a drug product in studies involving metabolism of the drug. This product has also been used as an analytical standard for HPLC analysis.</p>Fórmula:C28H20N8O2Pureza:Min. 95%Peso molecular:500.51 g/molBalsalazide 3-isomer
CAS:<p>Balsalazide 3-isomer (BZ3) is a diacid that is used as an anti-hypertensive drug. BZ3 has been shown to be a prodrug of balsalazide, which is converted in vivo to the active form by hydrolysis of the ester linkage. The prodrug approach was designed to provide an orally available agent for use in patients with colitis and ulcerative colitis. The synthetic process begins with the reaction of salicylic acid and bisoprolol to form the ester product, which then undergoes a second reaction with acetyl chloride to form the acyl chloride intermediate. This intermediate reacts with balsalazide and yields BZ3 when heated to high temperatures. BZ3 contains no impurities because it is synthesized from pure starting materials, whereas commercially available balsalazide may contain impurities such as salicylic acid or colitis.</p>Fórmula:C17H15N3O6Pureza:Min. 95%Peso molecular:357.32 g/mol2-Methoxy-5-sulfamoylbenzoic acid
CAS:<p>2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.<br>2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif</p>Fórmula:C8H9NO5SPureza:Min. 95%Peso molecular:231.23 g/mol2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane
CAS:<p>2-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyloxirane is a metabolite of the drug product 2-[[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]methyl]oxirane. It is an impurity in the drug product, which is a pharmaceutical intermediate that has been shown to have pharmacological properties. The CAS number for this compound is 63659-17-6 and it has been assigned the Chemical Abstracts Service (CAS) number of 63659-17-6. This compound has been characterized using HPLC and GC/MS methods.</p>Fórmula:C15H20O3Pureza:Min. 95%Peso molecular:248.32 g/mol3,4-Dimethoxy-2-methylpyridine-N-oxide
CAS:<p>3,4-Dimethoxy-2-methylpyridine-N-oxide is a potent inhibitor of somatostatin, which is known to play a role in the regulation of cancer cell growth and apoptosis. This compound has been shown to inhibit the activity of human kinases, including those involved in tumor cell proliferation. 3,4-Dimethoxy-2-methylpyridine-N-oxide is an anticancer agent that can be used to treat various types of cancer. It has also been found to have inhibitory effects on urine quetiapine and Chinese hamster ovary cells. The compound is a potent analog of kinase inhibitors and can be used as a lead compound for developing new drugs with anticancer properties.</p>Fórmula:C8H11NO3Pureza:Min. 95%Peso molecular:169.18 g/mol4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C20H27N4O4S2•ClPureza:Min. 95%Peso molecular:487.04 g/mol2-(Aminomethyl)-1-ethylpyrrolidine
CAS:<p>2-(Aminomethyl)-1-ethylpyrrolidine is a pharmaceutical preparation that has been used in the analytical method for determining impurities in pharmaceuticals. It has also been used as an intermediate for pharmaceutical dosage preparations and as a reagent for chromatographic analysis of various substances. 2-(Aminomethyl)-1-ethylpyrrolidine is produced by acylation of pyrrole with ethyl chloride, followed by hydrolysis with sodium carbonate and hydrochloric acid. The substance can be separated into its two components using chromatography, which is based on the difference in their polarity. 2-(Aminomethyl)-1-ethylpyrrolidine is a dopamine receptor antagonist that blocks uptake of dopamine into cells by inhibiting the dopamine transporter (DAT). This leads to increased levels of extracellular dopamine and subsequent activation of postsynaptic D2 receptors.</p>Fórmula:C7H16N2Pureza:Min. 95%Forma y color:Clear LiquidPeso molecular:128.22 g/molN-Hydroxy riluzole O-b-D-glucuronide
CAS:<p>N-Hydroxy riluzole O-b-D-glucuronide is an analytical standard and drug development metabolite. It is a metabolite of the anti-convulsant agent riluzole, which is used in the treatment of amyotrophic lateral sclerosis (ALS). Riluzole is converted to N-hydroxyl riluzole O-b-D-glucuronide in the liver by UDP glucuronosyltransferase. N-Hydroxyl riluzole O-b-D-glucuronide has been shown to block protein synthesis in rat kidney cells. It also blocks the conversion of amino acid tyrosine to dopa in dopaminergic neurons, and inhibits dopamine uptake into synaptosomes.</p>Fórmula:C14H13F3N2O8SPureza:Min. 95%Peso molecular:426.32 g/mol(3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine
CAS:<p>Granisetron is a drug that belongs to the group of serotonin receptor antagonists. It is used as an antiemetic, mainly in the prevention and treatment of nausea and vomiting caused by cancer chemotherapy and surgery. This drug has been shown to be effective in controlling nausea and vomiting, even when given after chemotherapy or surgical procedures. Granisetron hydrochloride was synthesized in 1988 by chemists at Hoffmann-La Roche. The synthesis was patented in 1990. Potential impurities are not listed on the USP or EP pharmacopeia, but these impurities have been detected during synthesis.</p>Fórmula:C9H18N2Pureza:Min. 95%Peso molecular:154.25 g/molSitagliptin hydroxy amide impurity
CAS:<p>Sitagliptin is an oral dipeptidyl peptidase-4 inhibitor that is used to treat type 2 diabetes. It binds to the active site of the enzyme and reversibly blocks the action of the enzyme, thereby inhibiting the breakdown of a number of important hormones such as glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide. Sitagliptin hydroxy amide impurity is an impurity in sitagliptin that inhibits oxidoreductases, enzymes that catalyze oxidation reactions. The enantiomeric purity of sitagliptin hydroxy amide impurity is unknown.</p>Fórmula:C16H14F6N4O2Pureza:Min. 95%Peso molecular:408.3 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
CAS:<p>6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone is a synthetic impurity standard that is used as a reference material in the analytical, natural and drug development, and metabolite studies. 6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone has a molecular weight of 390.27 and chemical formula C26H28N2O3S. It is also referred to by its CAS number 1391054-73-1.6</p>Fórmula:C28H27NO4SPureza:Min. 95%Peso molecular:473.58 g/mol1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone
CAS:<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).</p>Fórmula:C19H27N5O4Pureza:Min. 95%Peso molecular:389.45 g/molMethyl 3-aminocrotonate
CAS:<p>Methyl 3-aminocrotonate is an intermediate in the synthesis of pyridinedicarboxylic acid. It is a white powder with a melting point of 160-165°C and a boiling point of 263°C. Methyl 3-aminocrotonate is soluble in water, alcohols, ethers, chloroform, and benzene. It has been detected by its UV absorption at 227 nm. The detection sensitivity for this compound was found to be 0.1 ppm. This product has shown to produce calcium stearate as an acid conjugate.<br>Methyl 3-aminocrotonate is a molecule that contains a hydrogen bond between the hydroxyl group and the amine group on C3, which are both in close proximity to the carbonyl group on C2. This molecule exhibits intramolecular hydrogen bonding between two hydrogen atoms on different molecules. <br>The IR spectrum for methyl 3-aminoc</p>Fórmula:C5H9NO2Pureza:Min. 95%Forma y color:White To Yellow SolidPeso molecular:115.13 g/mol
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