Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65578 productos de "Derivados de Quinazolina y Quinolina"
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ethyl 5-(3-methoxyphenyl)-1H-pyrazole-4-carboxylate
CAS:Fórmula:C13H14N2O3Pureza:95.0%Peso molecular:246.2667-Aminoquinazoline-2,4(1H,3H)-dione
CAS:Fórmula:C8H7N3O2Pureza:97%Forma y color:SolidPeso molecular:177.1631-(6-CHLOROPYRIDIN-3-YL)CYCLOPROPANECARBOXYLIC ACID
CAS:Fórmula:C9H8ClNO2Pureza:97%Peso molecular:197.622-Chloro-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS:Pureza:95+%Peso molecular:253.52999885-(2-tert-Butoxycarbonylamino-ethyl)-1-phenyl-1H-pyrazole-4-carboxylic acid methyl ester
Fórmula:C18H23N3O4Pureza:95.0%Peso molecular:345.3991-(2-Trifluoromethylbenzyl)-1H-pyrazole-4-carboxylic acid
CAS:Fórmula:C12H9F3N2O2Peso molecular:270.2115-Morpholin-4-yl-pyridine-2-carboxylic acid tert-butyl ester
Fórmula:C14H20N2O3Pureza:95.0%Peso molecular:264.3251-(Pyridin-2-ylmethyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
Fórmula:C11H8F3N3O2Peso molecular:271.199Ethyl 3-(hydroxymethyl)-1-methyl-1H-pyrazole-5-carboxylate
CAS:Fórmula:C8H12N2O3Pureza:95%Peso molecular:184.195(4-acetyl-3,5-dimethyl-1H-pyrazol-1-yl)acetic acid
CAS:Fórmula:C9H12N2O3Pureza:95.0%Forma y color:White powderPeso molecular:196.2065-(5-Bromothiophen-2-yl)-1H-tetrazole
CAS:Fórmula:C5H3BrN4SPureza:99.0%Forma y color:Liquid, No data available.Peso molecular:231.075-(isopropoxymethyl)-8-quinolinol
CAS:Fórmula:C13H15NO2Pureza:95.0%Forma y color:SolidPeso molecular:217.268(2-Bromopyridin-4-yl)methanamine
CAS:Fórmula:C6H7BrN2Pureza:97%Forma y color:SolidPeso molecular:187.043-Fluoro-5-(trifluoromethyl)pyridine
CAS:Fórmula:C6H3F4NPureza:98.0%Forma y color:ClearPeso molecular:165.0914-Iodo-1-isopropyl-1H-pyrazole
CAS:Fórmula:C6H9IN2Pureza:98%Forma y color:Liquid, OilPeso molecular:236.0564-Bromo-6-fluoro-2-(trifluoromethyl)quinoline
CAS:Fórmula:C10H4BrF4NPureza:95.0%Peso molecular:294.0475-Bromo-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
CAS:Pureza:97%Peso molecular:286.95999151-(2-METHOXYETHYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
CAS:Fórmula:C7H10N2O3Pureza:95.0%Peso molecular:170.1685-Bromo-2-isopropoxypyridine
CAS:Fórmula:C8H10BrNOPureza:98%Forma y color:LiquidPeso molecular:216.078(4-CHLORO-6-(TRIFLUOROMETHYL)PYRIDIN-2-YL)METHANOL
CAS:Fórmula:C7H5ClF3NOPureza:95.0%Peso molecular:211.576-[2-(pyridin-3-yl)pyrrolidin-1-yl]pyridine-3-carboxylic acid
CAS:Fórmula:C15H15N3O2Pureza:95.0%Peso molecular:269.3041-Hydroxyisoquinoline-6-carboxylic acid
CAS:Fórmula:C10H7NO3Pureza:98%Forma y color:SolidPeso molecular:189.17Ethyl 1-(pyridin-3-yl)-1H-pyrazole-4-carboxylate
CAS:Fórmula:C11H11N3O2Pureza:97%Peso molecular:217.228(4-(2-Morpholinoethyl)phenyl)boronic acid
CAS:Fórmula:C12H18BNO3Pureza:95.0%Forma y color:SolidPeso molecular:235.09Ref: 10-F657698
1g99,00€5g270,00€10g437,00€25g832,00€100g2.066,00€2.5g171,00€100mg36,00€250mg45,00€500mg80,00€5-Chloro-1H-pyrazole-3-carboxylic acid
CAS:Fórmula:C4H3ClN2O2Pureza:98%Forma y color:SolidPeso molecular:146.531-(3-cyclopropyl-1H-pyrazol-5-yl)-N-methylmethanamine
CAS:Fórmula:C8H13N3Pureza:95.0%Peso molecular:151.213methyl 2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylate
CAS:Pureza:98%Peso molecular:221.13Ref: 10-F792875
1g584,00€5g1.565,00€10g2.320,00€2.5g1.134,00€50mg124,00€100mg175,00€250mg262,00€500mg468,00€2-Methyl-2-morpholinopropanal
CAS:Fórmula:C8H15NO2Pureza:95%Forma y color:Solid, AmorphousPeso molecular:157.213(5-Bromo-2-methoxypyridin-4-yl)boronic acid
CAS:Fórmula:C6H7BBrNO3Pureza:98%Forma y color:SolidPeso molecular:231.84tert-Butyl 4-(3-Aminopyridin-4-yl)piperazine-1-carboxylate
CAS:Fórmula:C14H22N4O2Pureza:95.0%Forma y color:SolidPeso molecular:278.356METHYL 2-(3-ETHYL-2,4-DIOXO-3,4-DIHYDROQUINAZOLIN-1(2H)-YL)ACETATE
CAS:Fórmula:C13H14N2O4Pureza:95.0%Peso molecular:262.2652,6-Dichloro-isonicotinic acid ethyl ester
CAS:Fórmula:C8H7Cl2NO2Pureza:97%Forma y color:SolidPeso molecular:220.052-Chloro-3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS:Fórmula:C12H17BClNO3Pureza:98%Forma y color:SolidPeso molecular:269.532-((5-Chloroquinolin-8-yl)oxy)-N,N-diethylethanamine dihydrochloride
CAS:Fórmula:C15H21Cl3N2OPureza:≥99%Peso molecular:351.73-Pyridin-2-yl-[1,2,4]oxadiazole-5-carboxylic acid ethyl ester
CAS:Fórmula:C10H9N3O3Pureza:95.0%Forma y color:Solid, No data available.Peso molecular:219.2ethyl 2-(3-chloropropanamido)-4-(3,4-dimethylphenyl)thiophene-3-carboxylate
CAS:Fórmula:C18H20ClNO3SPureza:95.0%Peso molecular:365.871-(2,2,2-trifluoroethyl)-1H-pyrazole-4-sulfonyl chloride
CAS:Fórmula:C5H4ClF3N2O2SPeso molecular:248.6{[4-(phenoxymethyl)-2-thienyl]methyl}amine hydrochloride
CAS:Fórmula:C12H14ClNOSPureza:95.0%Peso molecular:255.763-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzaldehyde oxime
Fórmula:C15H14F3N3OPureza:95.0%Peso molecular:309.292{2-[(4-Chloro-benzoyl)-(5-trifluoromethyl-pyridin-2-yl)-amino]-ethyl}-trimethyl-ammonium; iodide
Fórmula:C18H20ClF3IN3OPureza:95.0%Forma y color:SolidPeso molecular:513.735-Amino-1-(2,3-dimethyl-phenyl)-3-methyl-1H-pyrazole-4-carbonitrile
Fórmula:C13H14N4Pureza:95.0%Peso molecular:226.2831-(4-chlorophenyl)-2-(3-nitro-1H-pyrazol-1-yl)ethan-1-one
CAS:Fórmula:C11H8ClN3O3Pureza:95.0%Peso molecular:265.651-TERT-BUTYL-3-PHENYL-1H-PYRAZOL-5-AMINE
CAS:Fórmula:C13H17N3Pureza:95.0%Forma y color:SolidPeso molecular:215.32-Fluoro-6-morpholinoaniline
CAS:Fórmula:C10H13FN2OPureza:95.0%Forma y color:SolidPeso molecular:196.2254-Chloro-3-cyclopropylpyridine hydrochloride
CAS:Fórmula:C8H9Cl2NPureza:97%Forma y color:SolidPeso molecular:190.071-isobutyl-4-methyl-1H-pyrazol-5-amine hydrochloride
CAS:Fórmula:C8H16ClN3Pureza:95.0%Peso molecular:189.694-TERT-BUTYL 2-METHYL 2-METHYLMORPHOLINE-2,4-DICARBOXYLATE
CAS:Fórmula:C12H21NO5Pureza:97%Peso molecular:259.3022-Morpholino-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
CAS:Pureza:97%Peso molecular:346.230011Ethyl 4-hydroxyquinoline-3-carboxylate
CAS:Fórmula:C12H11NO3Pureza:98%Forma y color:SolidPeso molecular:217.2245-Hydroxy-nicotinic acid
CAS:Fórmula:C6H5NO3Pureza:97%Forma y color:Solid, Beige crystalline powderPeso molecular:139.112-Methoxy-4-(piperidin-3-yloxy)pyridinedihydrochloride
CAS:Fórmula:C11H18Cl2N2O2Peso molecular:281.184-bromo-1-ethyl-3,5-dimethyl-1H-pyrazole
CAS:Fórmula:C7H11BrN2Pureza:≥95%Forma y color:LiquidPeso molecular:203.0836-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]pyridine-3-carboxylic acid
CAS:Fórmula:C13H19N3O4Pureza:95.0%Peso molecular:281.3125-Bromo-2-ethoxynicotinic acid
CAS:Fórmula:C8H8BrNO3Pureza:≥95%Forma y color:Solid, Brown solidPeso molecular:246.06ETHYL 1-(4-FLUOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE
CAS:Fórmula:C12H11FN2O2Pureza:98%Peso molecular:234.23Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Fórmula:C15H13NO3Forma y color:SolidPeso molecular:255.27Ticlopidine
CAS:<p>Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.</p>Fórmula:C14H14ClNSPureza:99.67%Forma y color:SolidPeso molecular:263.79Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Fórmula:C21H27NOForma y color:Needles From Petroleum Ether SolidPeso molecular:309.45Itopride free base
CAS:<p>Itopride HCl combats dyspepsia and GERD, inhibiting AChE and blocking D2 receptors.</p>Fórmula:C20H26N2O4Forma y color:WhitePeso molecular:358.43Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Forma y color:White SolidPeso molecular:331.15Meclofenamic acid
CAS:<p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>Fórmula:C14H11Cl2NO2Pureza:98%Forma y color:SolidPeso molecular:296.15Prothioconazole
CAS:<p>Prothioconazole (Proline 480 SC Fungicide) is a chiral triazole fungicide in plant pathogen control.</p>Fórmula:C14H15Cl2N3OSPureza:99.77%Forma y color:Un3077 9/Pg 3Peso molecular:344.26Pardoprunox
CAS:<p>Pardoprunox (SLV-308) is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.</p>Fórmula:C12H15N3O2Pureza:98%Forma y color:SolidPeso molecular:233.27Procymidone
CAS:<p>Procymidone is a broad-spectrum fungicide that inhibits fungal glycerol triester synthesis, thereby disrupting hyphal growth. androgen receptor (AR) antagonist</p>Fórmula:C13H11Cl2NO2Pureza:99.86%Forma y color:Colorless SolidPeso molecular:284.14Penbutolol sulfate
CAS:<p>Penbutolol sulfate ((-)-Terbuclomine) is able to bind to both β2-adrenergic receptor and β1-adrenergic receptor, thus making it a non-selective β blocker.</p>Fórmula:C18H29NO2H2O4SPureza:98.55%Forma y color:SolidPeso molecular:340.47Betrixaban
CAS:<p>Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.</p>Fórmula:C23H22ClN5O3Pureza:99.33%Forma y color:SolidPeso molecular:451.91Mephenoxalone
CAS:<p>Mephenoxalone is a muscle relaxant and mild anxiolytic. It inhibits neuron transmission and relaxing skeletal muscles by inhibiting the reflex arc.</p>Fórmula:C11H13NO4Pureza:98%Forma y color:SolidPeso molecular:223.23Icotinib
CAS:<p>Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.</p>Fórmula:C22H21N3O4Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:391.42(3S,4S)-Tofacitinib
CAS:<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Fórmula:C16H20N6OPureza:98%Forma y color:SolidPeso molecular:312.37Diclazuril 6-Carboxylic Acid Butyl Ester
CAS:Producto controlado<p>Applications Diclazuril 6-carboxylic acid butyl ester is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity. Coccidiostat.<br>References Maes, L., et al.: J. Parasitol., 74, 931 (1988),<br></p>Fórmula:C22H17Cl3N4O4Forma y color:NeatPeso molecular:507.75Ethionamide Sulfoxide-D3
CAS:Producto controladoFórmula:C8D3H7N2OSForma y color:NeatPeso molecular:185.263-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin
CAS:Producto controlado<p>Applications 3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)<br></p>Fórmula:C26H23F9N6O2Forma y color:NeatPeso molecular:622.4854Benperidol
CAS:<p>Applications Benperidol is an antipsychotic which can be used for the treatment of schizophrenia, but is primarily used to control antisocial hypersexual behaviour.<br>References Bobon, J., et al.: Acta Neurol Belg, 63, 839-43 (1963);<br></p>Fórmula:C22H24FN3O2Forma y color:White To Off-WhitePeso molecular:381.444-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
CAS:Producto controlado<p>Applications 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug.<br>References Liao, H., et al.: Tetrahedron: Asymmetry, 28, 105, (2017)<br></p>Fórmula:C13H10ClN3O2SForma y color:NeatPeso molecular:307.765-Methyl-5-propyl-2-dioxanone (80%)
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Fórmula:C8H14O3Pureza:80%Forma y color:NeatPeso molecular:158.191-Dehydroxy Terfenadine
CAS:Producto controladoFórmula:C32H41NOForma y color:NeatPeso molecular:455.67Efavirenz Amino Alcohol Ethyl Carbamate
CAS:Producto controlado<p>Applications Efavirenz Amino Alcohol Ethyl Carbamate is used in the synthesis of Efavirenz (E425000), a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Antiviral<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)<br></p>Fórmula:C16H15ClF3NO3Forma y color:NeatPeso molecular:361.74Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride
CAS:Producto controlado<p>Applications Thiazol-5-ylmethyl ((2R,5R)-5-Amino-1,6-diphenylhexan-2-yl)carbamate Hydrochloride is an impurity of Cobicistat (C633150), a HIV protease inhibitor that has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer.<br>References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012)<br></p>Fórmula:C23H27N3O2S·HClForma y color:NeatPeso molecular:446.02-(2-Methoxyethyl)phenol
CAS:Producto controlado<p>Applications 2-(2-Methoxyethyl)phenol is used as a stabilizer in the preparation of polysiloxane based coating compounds with good stability.<br></p>Fórmula:C9H12O2Forma y color:NeatPeso molecular:152.194-{[(p-Fluorophenyl)imino]methyl}phenol
CAS:Producto controlado<p>Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.<br>References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);<br></p>Fórmula:C13H10FNOForma y color:NeatPeso molecular:215.22cis-Hydroxy Solifenacin N-Oxide(Mixture of Diastereomers)
Producto controlado<p>Applications Solifenacin (S676700) metabolite.<br></p>Fórmula:C23H26N2O4Forma y color:NeatPeso molecular:394.464-(Methylamino)-3-nitrobenzoic Acid
CAS:Producto controlado<p>Applications 4-(Methylamino)-3-nitrobenzoic Acid (cas# 41263-74-5) is a compound useful in organic synthesis.<br></p>Fórmula:C8H8N2O4Forma y color:NeatPeso molecular:196.164-O-Des(difluoromethyl) Roflumilast
CAS:Producto controladoFórmula:C16H14Cl2N2O3Forma y color:NeatPeso molecular:353.20N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester
CAS:Producto controlado<p>Impurity Ritonavir EP Impurity J<br>Applications N-[(1S,2S,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]carbamic Acid 5-Thiazolylmethyl Ester (Ritonavir EP Impurity J) is an intermediate in the synthesis of Ritonavir (R535000), a selective HIV protease inhibitor used for the treatment of HIV infections and AIDS.<br>References Hamada, Y., et al.: Bioorg. Med. Chem., 10, 4155 (2002);<br></p>Fórmula:C28H35N3O5SForma y color:White To Off-WhitePeso molecular:525.66Elvitegravir-d6 (Major)
CAS:Producto controlado<p>Applications A novel labelled inhibitor of human immunodeficiency virus type 1 integrase.<br>References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),<br></p>Fórmula:C23H17D6ClFNO5Forma y color:NeatPeso molecular:453.914-(1-Methylethenyl)-2-propyl-1H-imidazole-5-carboxylic Acid Ethyl Ester
CAS:Producto controlado<p>Applications Olmesartan intermediate.<br>References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996),<br></p>Fórmula:C12H18N2O2Forma y color:NeatPeso molecular:222.283-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS:Producto controlado<p>Applications 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a useful synthetic intermediate in the synthesis of Ibrutinib (I124970); a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011); Li, X., et al.: J. Med. Chem., 58, 9625 (2015)<br></p>Fórmula:C17H13N5OForma y color:Light Brown To BrownPeso molecular:303.32(3Z)-2,3-Dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid Methyl Ester
CAS:Producto controladoFórmula:C24H21N3O3Forma y color:NeatPeso molecular:399.44Thalidomide
CAS:Producto controlado<p>Applications Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Fórmula:C13H10N2O4Forma y color:NeatPeso molecular:258.232-N-Propyl Pramipexole
CAS:Producto controlado<p>Impurity Pramipexole EP Impurity B; Pramipexole BP Impurity B<br>Applications 2-N-Propyl Pramipexole (Pramipexole EP Impurity B; Pramipexole BP Impurity B) is a Pramipexole derivative.<br></p>Fórmula:C13H23N3SForma y color:NeatPeso molecular:253.41Ibrutinib Addition Adduct with (R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)
CAS:Fórmula:C47H46N12O3Forma y color:Off-WhitePeso molecular:826.952-Cyano-3-(3-chlorophenylethyl)pyridine
CAS:Producto controladoFórmula:C14H11ClN2Forma y color:NeatPeso molecular:242.70Ivabradine-d3 Hydrochloride
CAS:Producto controlado<p>Stability very hygroscopic<br>Applications Labelled Ivabradine (I940500). Selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),<br></p>Fórmula:C272H3H33N2O5·ClHForma y color:NeatPeso molecular:508.06Tavaborole (>90%)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tavaborole is a topical treatment of toenail onychomycosis.<br>References Toledo-Bahena, M.E. et. al.: J. Drugs Dermatol., 13, 1124 (2014)<br></p>Fórmula:C7H6BFO2Pureza:>90%Forma y color:NeatPeso molecular:151.93(E)-Naftifine
CAS:<p>Applications (E)-Naftifine is an intermediate in synthesizing Naftifine N-Oxide (N213110), which is an impurity or metabolite of Naftifine Hydrochloride (N213100), an allylamine antifungal agent.<br>References Georgopoulos, A., et al.: Antimicrob. Ag. Chemother., 19, 386 (1981); Meingassner, J.C., et al.: J. Invest. Dermatol., 77, 444 (1981); Paltauf, F., et al.: Biochim Biophys. Acta, 712, 268 (1982); Aggarwal, D., et al.: J. Pharm. Pharmacol., 56, 1509 (2004)<br></p>Fórmula:C21H21NForma y color:NeatPeso molecular:287.405-Acetyl-2-propyl-1H-Imidazole-4-carboxylic Acid Ethyl Ester
CAS:Producto controlado<p>Applications 5-Acetyl-2-propyl-1H-Imidazole-4-carboxylic Acid Ethyl Ester is used in the synthetic preparation of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds.<br>References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996);<br></p>Fórmula:C11H16N2O3Forma y color:NeatPeso molecular:224.26Hydroxy Celecoxib
CAS:Producto controlado<p>Applications A metabolite of Celecoxib (C251000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997), Paulson, S., et al.: Drug Metab. Dispos., 28, 308 (2000), Kirchheiner, J., et al.: Clin. Pharmacol. Ther., 71, 286 (2002),<br></p>Fórmula:C17H14F3N3O3SForma y color:NeatPeso molecular:397.37(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl
CAS:Producto controlado<p>Applications Tadalafil (T004500) derivative. Used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity.<br>References Beghyn, T. et al.: Bioorgan. Med. Chem. Lett. 17, 789(2007)<br></p>Fórmula:C20H18N2O4Forma y color:Off White SolidPeso molecular:350.371-Phenyl-2-propen-1-one (Contains ~1% BHT as stabilizer)
CAS:<p>Stability Light and Temperature Sensitive<br>Applications 1-Phenyl-2-propen-1-one is a chemical reagent used in the synthesis of pharmaceutical agents. Used in the preparation of functionalized aminoindolizines as well as pyrano[3,2-x]coumarins.<br>References Wang, D. et al.: Asian J. Org. Chem., 2, 480 (2013); Gohain, M. et al.: Tetrahedron Lett., 54, 3773 (2013);<br></p>Fórmula:C9H8OForma y color:NeatPeso molecular:132.159De(2,3-dihydroxy) Nadolol Hydrochloride
CAS:Producto controlado<p>Applications De(2,3-dihydroxy) Nadolol Hydrochloride is an impurity of Nadolol (N201050), a β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977); Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978); Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980)<br></p>Fórmula:C17H27NO2·ClHForma y color:NeatPeso molecular:313.86Lacidipine Monomethyl Ester
CAS:Producto controlado<p>Applications Lacidipine Monomethyl Ester is an impurity of Lacidipine (L098000); a dihydropyridine calcium channel blocker. Antihypertensive.<br>References Mohan, Arivozhi., et al.: J. AOAC Int., 94(6), 1800-1806 (2011); Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989); Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002); McCormack, A.J., et al.: Drugs, 63, 2327 (2003)<br></p>Fórmula:C25H31NO6Forma y color:NeatPeso molecular:441.52N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Producto controlado<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br></p>Fórmula:C16H15N5Forma y color:NeatPeso molecular:277.32(±)-2-Phenylpropanoic Acid
CAS:<p>Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.<br>References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);<br></p>Fórmula:C9H10O2Forma y color:Light Yellow LiquidPeso molecular:150.17trans-Hydroxy Praziquantel-d5
CAS:Producto controlado<p>Applications Labelled trans-Hydroxy Praziquantel (H952405). The main cis-monohydroxylated metabolite of Praziquantel (P702095).<br>References Buehring, K., et al.: Eur. J. Drug Metab. Pharm., 3, 179 (1978), Moldeus, P., et al.: Methods Enzymol., 52, 60 (1978), Cioli, D., et al.: Pharmacol. Ther., 68, 35 (1995),<br></p>Fórmula:C19H19D5N2O3Forma y color:NeatPeso molecular:333.443-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone Impurity)
CAS:Producto controladoFórmula:C23H27FN4O2Forma y color:NeatPeso molecular:410.484-Butyrylamino-3-methyl-5-nitrobenzoic Acid Methyl Ester
CAS:Producto controlado<p>Applications 4-Butyrylamino-3-methyl-5-nitrobenzoic Acid Methyl Ester is a useful synthetic intermediate in the production of Telmisartan, an antihypertensive drug. 4-Butyrylamino-3-methyl-5-nitrobenzoic Acid Methyl Ester is part of a more efficient process of synthesizing Telmisartan in terms of impurity, yield, cost, and large-scale production.<br>References Reddy, K., et al.: Org. Process Res. Dev., 11, 81 (2007)<br></p>Fórmula:C13H16N2O5Forma y color:NeatPeso molecular:280.28R-Mirtazapine
CAS:Producto controlado<p>Applications R-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects.<br>References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)<br></p>Fórmula:C17H19N3Forma y color:NeatPeso molecular:265.35S-(+)-Atomoxetine Hydrochloride
CAS:Producto controlado<p>Impurity Atomoxetine EP Impurity B<br>Applications ent S-(+)-Atomoxetine Hydrochloride (Atomoxetine EP Impurity B) is an enatiomer of Atomoxetine, a Norepinephrine uptake blocker.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Robertson, D., et al.: J. Med. Chem., 31, 1412 (1988), Hwamg, et al.: Neurosci. Lett., 265, 151 (1999),<br></p>Fórmula:C17H21NO·ClHForma y color:NeatPeso molecular:291.82Everolimus Isomer C (>60%, contains everolimus)
CAS:Producto controlado<p>Stability Unstable in solution, revert back to Everolimus<br>Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Fórmula:C53H83NO14Forma y color:NeatPeso molecular:958.22Methylene-Bis Paroxetine Dihydrochloride
CAS:Producto controlado<p>Impurity Paroxetine EP Impurity F<br>Applications Methylene-Bis Paroxetine Dihydrochloride (Paroxetine EP Impurity F) is used in the chiral HPLC method for chiral purity determination of Paroxetine drug substance.<br>References Zukowski, J., et al.: Chirality, 15, 600 (2003),<br></p>Fórmula:C39H42Cl2F2N2O6Forma y color:NeatPeso molecular:743.66Ofloxacin N-Oxide Hydrochloride
CAS:Producto controladoFórmula:C18H20FN3O5·ClHForma y color:Off-WhitePeso molecular:413.83(2R,5R)-1,6-Diphenylhexane-2,5-diamine Dihydrochloride
CAS:Producto controladoFórmula:C18H24N2·2ClHForma y color:NeatPeso molecular:341.31845-Chloro-6-(piperidin-1-yl)pyrimidine-2,4-diamine
CAS:Producto controlado<p>Applications 5-Chloro-6-(piperidin-1-yl)pyrimidine-2,4-diamine is used for biological studies and has potential use in pharmaceutical compositions.<br>References Xiang, F.: Faming Zhuanli Shenqing. 39 pp. (2019)<br></p>Fórmula:C9H14ClN5Forma y color:NeatPeso molecular:227.691-(6-Methylpyridin-3-yl)-2-((4-(2-(6-methylpyridin-3-yl)-2-oxoethyl)phenyl)sulfonyl)ethanone
CAS:Producto controladoFórmula:C22H20N2O4SForma y color:NeatPeso molecular:408.47Olanzapine Lactam Impurity
CAS:<p>Impurity Olanzapine ketolactam impurity<br>Applications A degradation product of Olanzapine (LY170053) (O253750) in solid oral formulations.<br>References Chakrabarti, J., et al.: J.Med. Chem., 25, 1133 (1982), Chafetz, L., et al.: J. Pharm. Sci., 73, 1186 (1984), Hartauer, K., et al.: Pharm. Dev. Technol., 5, 303 (2000),<br></p>Fórmula:C17H20N4O2Forma y color:NeatPeso molecular:312.37N-Desethyl N-Methyl Rivastigmine
CAS:Producto controlado<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Fórmula:C13H20N2O2Forma y color:NeatPeso molecular:236.32O-De(3-fluorobenzyl) Lapatinib Ditosylate Salt
CAS:Producto controlado<p>Applications A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.<br>References He, K., et al.: Chem. Res. Toxicol., 11, 252 (1998), Rusnuk, D., et al.: Cancer Res., 61, 7196 (2001), Li, X., et al.: Drug Metab. Dispos., 37, 1242 (2009),<br></p>Fórmula:C36H37ClN4O10S3Forma y color:NeatPeso molecular:817.35Paliperidone N-Oxide
CAS:Producto controlado<p>Impurity Paliperidone USP Related Compound D<br>Applications One of the major degradation product of Risperidone in bulk drug and pharmaceutical dosage forms. Paliperidone USP Related Compound D.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leysen, J., et al.: J. Pharmacol. Exp. Ther., 247, 661 (1988), Huang, M., et al.: Pharm. Drug Dispos., 54, 257 (1993), Smyth, W., et al.: Anal. Bioanal. Chem., 378, 1305 (2004),<br></p>Fórmula:C23H27FN4O4Forma y color:NeatPeso molecular:442.48Atazanavir-d9
CAS:Producto controlado<p>Applications Atazanavir-d9 is the deuterated analog of Atazanavir (A790051), a azapeptide HIV protease inhibitor derivative. Atazanavir have been investigated as potential treatment of human immunodeficiency virus (HIV) and for anticancer purposes.<br>References Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),<br></p>Fórmula:C382H15H37N6O7Forma y color:NeatPeso molecular:719.95Hydroxynorketamine Hydrochloride
CAS:Producto controlado<p>Applications Hydroxynorketamine is a metabolite of Ketamine (K165300, HCl salt) which is a medication used mainly for starting and maintaining anesthesia.<br>References Adams, J., et al.: Biomed. Mass Spec., 11, 527 (1981); Sass, W.C., et al.: Anal. Profiles Drug Subs., 6, 297 (1977); Reich, D.L., et al.: Can. J. Anaesth., 36, 186 (1989)<br></p>Fórmula:C12H15Cl2NO2Forma y color:White To Off-WhitePeso molecular:276.166a-Naloxol
CAS:Producto controlado<p>Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.<br>References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Fórmula:C19H23NO4Forma y color:NeatPeso molecular:329.39Olanzapine Dimer Impurity
Producto controlado<p>Applications An impurity of Olanzapine (O253750), a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Neuroprotective product.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C29H28N6S2Forma y color:NeatPeso molecular:524.703N-Des(4-Fluorophenyl)-N-(3-chlorophenyl)-ezetimibe
CAS:Producto controladoFórmula:C24H21ClFNO3Forma y color:NeatPeso molecular:425.88
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