Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65941 productos de "Derivados de Quinazolina y Quinolina"
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Sitagliptin Carbamoyl β-D-Glucuronide Sodium Salt
CAS:Producto controladoFórmula:C23H22F6N5NaO9Forma y color:NeatPeso molecular:649.431-Methyl-3-phenylpiperazine
CAS:Producto controlado<p>Applications Piperazine derivative used as reference materials for forensic laboratories. They affect the central and the autonomic nervous systems, the blood pressure, and smooth muscle.<br>References Brady, J., et al.: Drug Dev. Res., 20, 231 (1990), Winter, J., et al.: J. Pharmacol. Exp. Ther., 262, 682 (1992), Ator, N., et al.: Eur. J. Pharmacol., 241, 237 (1993), Forster, E., et al.: Eur. J. Pharmacol., 281, 81 (1995),<br></p>Fórmula:C11H16N2Forma y color:Off WhitePeso molecular:176.26Pentoxifylline-d6
CAS:Producto controlado<p>Applications A labelled metabolite of Pentifylline. Methylxanthine derivative that improves blood flow by decreasing blood viscosity. Phosphodiesterase inhibitor. Inhibits the synthesis of tumor necrosis factor α (TNF-α).<br>References Ward, A., et al.: Drugs, 34, 50 (1987), Samlaska, C.P., et al.: J. Am. Acad. Dermatol., 30, 603 (1994), Poulakis, et al.: Respir. Med., 93, 52 (1999), Reuter, et al.: Am J. Physiol., 277, 854 (1999),<br></p>Fórmula:C132H6H12N4O3Forma y color:NeatPeso molecular:284.34Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
CAS:Pureza:95.0%Peso molecular:351.45999145507812-(2,6-Dimethylbenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:288.35998535156254’-Hydroxyphenyl Carvedilol
CAS:Producto controlado<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Fórmula:C24H26N2O5Forma y color:Off White SolidPeso molecular:422.471,3-Diphenyl-1 H -pyrazole-4-carboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:264.28399658203125Clozapine N-Oxide
CAS:Producto controlado<p>Impurity CLOZAPINE N-OXIDE IMPURITY<br>Applications Clozapine N-Oxide is a 5-HT2 antagonist. It is a major metabolite of clozapine (C587500) that can be monitored by HPLC.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baldessarini, E., et al.: Neuropsychopharmacol., 9, 117 (1993); Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994); Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)<br></p>Fórmula:C18H19ClN4OForma y color:Light Yellow To YellowPeso molecular:342.82N,O-Dibenzoyl-DL-tyrosyl-N’,N’-dipropylamide
CAS:Producto controlado<p>Applications N,O-Dibenzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B.<br>References Janssen, et al.: J. Pharm. Pharmacol., 9, 381 (1956), Bertaccini, et al.: Br. J. Pharmac., 34, 310 (1968),<br></p>Fórmula:C29H32N2O4Forma y color:White To Light RedPeso molecular:472.585-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:345.4200134277344Desfluoro Ezetimibe
CAS:Producto controlado<p>Impurity Ezetimibe Desfluoroaniline Analog (USP)<br>Stability Hygroscopic<br>Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).<br>References Anon.: IP.com J., 7, 4 (2007);<br></p>Fórmula:C24H22FNO3Forma y color:White To Off-WhitePeso molecular:391.432,3,4-Trimethoxybenzaldehyde
CAS:Producto controlado<p>Applications 2,3,4-Trimethoxybenzaldehyde is a trimethoxylated aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an impurity of the anti-anginal drug Trimetazidine (T795610).<br>References Medenica, M.B. et al.: J. Chrom. Sci., 46, 430 (2008);<br></p>Fórmula:C10H12O4Forma y color:Off-WhitePeso molecular:196.20DL-Fenfluramine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications N-Ethyl-α-methyl-3-(trifluoromethyl)-benzeneethanamine hydrochloride has been used in case studies for the study of impulsivity, motor skills, and anxiogenic effects in the neuroscience community.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whitney, K.N., et al.: Exp. Clin. Psychopharm., 21, 345-54 (2013); Arrant, A.E., et al.: Neuropharmacology, 65, 213-22 (2013)<br></p>Fórmula:C12H16F3N·ClHForma y color:WhitePeso molecular:267.722-methyl-2-(4-morpholinyl)propanoic acid hydrochloride hydrate
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:227.69000244140625Pomalidomide-(d4 major)
CAS:Producto controlado<p>Applications Pomalidomide-d4 is the labeled anaxlogue of Pomalidomide (P688200), a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Fórmula:C13H7D4N3O4Forma y color:NeatPeso molecular:277.27Epinephrine Sulfonic Acid-d3
CAS:Producto controlado<p>Applications A labelled Epinephrine (E588585) derivative formed in injection solutions and eye drops during sterilization and storage of L-Epinephrine Bitartrate.<br>References De Mol, N.J. et al.: Pharmac. Week., 117, 1 (1982); Liu, C. et al.: Yao. Fen. Zaz., 2, 200 (1982);<br></p>Fórmula:C9H10D3NO5SForma y color:Light BrownPeso molecular:250.294-Desmethyl-3-methyl Celecoxib
CAS:Producto controlado<p>Impurity Celecoxib Related Compound A<br>Applications 4-Desmethyl-3-methyl Celecoxib is a meta positional isomer of Celecoxib (C251000) with selective inhibitory activity against human cyclooxygenase-2. USP Celecoxib Related Compound A<br>References Sreenivas, R.D. et al.: J. Pharmac. Biomed. Anal., 25, 21 (2001);<br></p>Fórmula:C17H14F3N3O2SForma y color:White To Light YellowPeso molecular:381.37Brivaracetam related compound D (~85:15 d.r.)
CAS:Producto controlado<p>Applications (αS,4R)-α-Ethyl-2-oxo-4-propyl-1-pyrrolidineacetic Acid is a impurity of Brivaracetam (B677645) which is a 4-n-propyl analog of levetiracetam (L331500), and a racetam derivative with anticonvulsant properties.<br>References Rosenstiel, P., et al.:Neurotherapeutics, 4 (1), 84 (2007); Malawska, B., et al.:, Curr. Opin. Investig. Drugs, 6(7), 740 (2005);<br></p>Fórmula:C11H19NO3Forma y color:NeatPeso molecular:213.273[3-(1H-Pyrazol-1-yl)phenyl]methylamine
CAS:Fórmula:C10H11N3Pureza:95%Forma y color:LiquidPeso molecular:173.2191-Hydroxycyclopentyl 2-chlorophenyl Ketone
CAS:Producto controladoFórmula:C12H13ClO2Forma y color:Colourless To Light YellowPeso molecular:224.685,5-Diphenyl Hydantoin Sodium
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 5,5-Diphenyl Hydantoin Sodium salt reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007), Guo, D., et al.: J. Biol. Chem., 282, 36766 (2007), Merrell, M., et al.: Drug Metab. Dispos., 36, 1716 (2008),<br></p>Fórmula:C15H11N2O2·NaForma y color:NeatPeso molecular:274.255-Amino-1-benzo[1,3]dioxol-5-yl-3-methyl-1H-pyrazole-4-carbonitrile
Pureza:95.0%Peso molecular:242.23800659179688Pyrimethamine-d3
CAS:Producto controlado<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Fórmula:C12H10D3ClN4Forma y color:Off-WhitePeso molecular:251.73Gabapentin-d6 Hydrochloride
CAS:Producto controlado<p>Applications Gabapentin Hydrochloride is a salt analogue of Gabapentin-d6 (G117253), a labelled amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.O. et al.: Arzneim.-Forsch., 36, 830 (1986); Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9H11D6NO2·HClForma y color:NeatPeso molecular:213.73Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Fórmula:C13H13D3NNaO8Forma y color:Off-White To Light BeigePeso molecular:340.283,5-Dimethyl-1H-pyrazole-4-sulfonyl chloride hydrochloride
CAS:Fórmula:C5H8Cl2N2O2SPureza:97%Forma y color:SolidPeso molecular:231.09Propoxyphenyl Thiosildenafil
CAS:Producto controlado<p>Applications Propoxyphenyl-thiosildenafil is an analogue of Thiosildenafil (T371500). Propoxyphenyl-thiosildenafil has been used in the preparation of novel pyrazolopyrimidinethiones as PDE5 inhibitors for treating erectile dysfunction.<br></p>Fórmula:C23H32N6O3S2Forma y color:NeatPeso molecular:504.67Riociguat
CAS:Producto controlado<p>Applications Riociguat is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C20H19FN8O2Forma y color:NeatPeso molecular:422.41572-(4-morpholinyl)-8-quinolinol
CAS:Pureza:95.0%Forma y color:Liquid, OilPeso molecular:230.266998291015622-Hydroxy-6-(trifluoromethyl)nicotinamide
CAS:Fórmula:C7H5F3N2O2Pureza:≥97%Forma y color:SolidPeso molecular:206.124[2'-(5-ethyl-3,4-diphenyl-pyrazol-1-yl)-biphenyl-3-yloxy]acetic acid
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:474.559997558593753-Cyclopropyl-1-phenyl-1H-pyrazol-5-amine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:199.25700378417975-(6-Methoxynaphthalen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:268.2720031738281O-Desmethyl Gefitinib
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A major metabolite of Gefitinib.<br>References Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002), Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003), McKillop, D., et al.: Xenobiotica, 10, 917 (2004),<br></p>Fórmula:C21H22ClFN4O3Forma y color:YellowPeso molecular:432.884-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde
CAS:<p>Impurity Bisoprolol EP Impurity L (Metoprolol EP Impurity C)<br>Stability Hygrscopic<br>Applications 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde (Bisoprolol EP Impurity L (Metoprolol EP Impurity C)) is a Metoprolol impurity .<br>References Baldwin, J.J. , et al.: J. Med. Chem., 29, 1065 (1986), Ravelet, C., et al.: J. Sep. Sci., 29, 1322 (2006),<br></p>Fórmula:C13H19NO3Forma y color:NeatPeso molecular:237.295-Chloro-N-cyclohexylpentanamide
CAS:<p>Stability Hygroscopic<br>Applications 5-Chloro-N-cyclohexylpentanamide (cas# 15865-18-6) is a compound useful in organic synthesis.<br></p>Fórmula:C11H20ClNOForma y color:NeatPeso molecular:217.7366-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (Lornoxicam)
CAS:Pureza:97.0%Peso molecular:371.80999755859375
![5-Methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF358068.webp&w=3840&q=75)
![[3-(1H-Pyrazol-1-yl)phenyl]methylamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF065384.webp&w=3840&q=75)
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![[2'-(5-ethyl-3,4-diphenyl-pyrazol-1-yl)-biphenyl-3-yloxy]acetic acid](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF049791.webp&w=3840&q=75)
![4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH946735.webp&w=3840&q=75)
![6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF069199.webp&w=3840&q=75)