Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65924 productos de "Derivados de Quinazolina y Quinolina"
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3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Producto controlado<p>Impurity Risperidone EP Impurity L<br>Applications 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C11H15ClN2OForma y color:NeatPeso molecular:226.707-(4-Iodobutoxy)-3,4-dihydroquinolin-2-one
CAS:Producto controlado<p>Impurity Aripiprazole Iodobutoxyquinoline Impurity<br>Applications An impurity in the synthesis of Aripiprazole (A771000). A degradation product in Aripiprazole tablets. Aripiprazole Iodobutoxyquinoline Impurity<br>References Shah, V., et al.: J. Pharm. Sci., et al.: 81, 309 (1992), Zuo, X., et al.: Chromatographia, 64, 387 (2006),<br></p>Fórmula:C13H16INO2Forma y color:Off-WhitePeso molecular:345.182,6-Dimethoxypyridine-3,5-diamine hydrochloride
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:205.639999389648442-(3,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:329.190002441406252-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5,6-dimethylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:245.28599548339844Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Fórmula:C21H25N3·2HClPureza:98.45%Forma y color:SolidPeso molecular:392.37Methyl 6-bromo-2-(4-methoxyphenyl)quinoline-4-carboxylate
CAS:Pureza:95.0%Peso molecular:372.2179870605469Chlorobenzene
CAS:Producto controlado<p>Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),<br></p>Fórmula:C6H5ClForma y color:Clear ColourlessPeso molecular:112.568-benzyl-4-(pyridine-3-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:381.4320068359375(S)-Ibrutinib
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications (S)-Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References Pan, Z., et. al.: ChemMedChem, 2, 58 (2007)<br></p>Fórmula:C25H24N6O2Forma y color:NeatPeso molecular:440.5Quinoxyfen
CAS:Producto controlado<p>Applications Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Corrales, M., et al.: Food Chem. Toxicol., 48, 3471 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5897 (2010),<br></p>Fórmula:C15H8Cl2FNOForma y color:Off-WhitePeso molecular:308.13Methomyl
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Methomyl is a carbamate insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Armes, N., et al.: Bull. Entomol. Res., 86, 499 (1996); Shono, T., et al.: Pest. Biochem. Physiol., 75, 1 (2003)<br></p>Fórmula:C5H10N2O2SForma y color:ColourlessPeso molecular:162.211-(2-Methoxyphenyl)piperazine
CAS:Producto controlado<p>Applications A piperazine derivative and a selective antagonist at D3 receptors that influences the expression of cocaine-induced conditioned place preference (CPP).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Byrska, B. et al.: Zagadnien Nauk Sadowych 81, 101 (2010); Cervo, L. et al.: Pharmacol Biochem Be 82, 727 (2005)<br></p>Fórmula:C11H16N2OForma y color:NeatPeso molecular:192.26Norfloxacin Nicotinate
CAS:Producto controlado<p>Applications Norfloxacin nicotinate is a fluoroquinolone antibacterial agent that is a norfloxacin derivative with improved solubility in water.<br></p>Fórmula:C16H18FN3O3·C6H5NO2Forma y color:NeatPeso molecular:319.33 + (123.11)6-ethoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:285.36999511718751-(8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-5-yl)ethanone
CAS:Fórmula:C20H21ClN4OForma y color:White To Off-WhitePeso molecular:368.86Acetaminotadalafil
CAS:Producto controlado<p>Applications Acetaminotadalafil, is a new analogue of Tadalafil (T004500), used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),<br></p>Fórmula:C23H20N4O5Forma y color:NeatPeso molecular:432.434-ethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718752-(4-n-Butoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:332.4100036621094Clozapine N-Oxide
CAS:Producto controlado<p>Impurity CLOZAPINE N-OXIDE IMPURITY<br>Applications Clozapine N-Oxide is a 5-HT2 antagonist. It is a major metabolite of clozapine (C587500) that can be monitored by HPLC.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baldessarini, E., et al.: Neuropsychopharmacol., 9, 117 (1993); Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994); Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)<br></p>Fórmula:C18H19ClN4OForma y color:Light Yellow To YellowPeso molecular:342.823-Hydroxy Citalopram
CAS:<p>Impurity Citalopram EP Impurity B<br>Applications 3-Hydroxy Citalopram (Citalopram EP Impurity B) is a Citalopram (C505000) impurity.<br></p>Fórmula:C20H21FN2O2Forma y color:NeatPeso molecular:340.395-(benzo[d]thiazol-2-yl)thiophene-2-carbonyl chloride
CAS:Pureza:95.0%Peso molecular:279.7600097656254’-Hydroxyphenyl Carvedilol
CAS:Producto controlado<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Fórmula:C24H26N2O5Forma y color:Off White SolidPeso molecular:422.47Mebeverine Alcohol
CAS:Producto controlado<p>Applications A metabolite of Mebeverine (M202490), an antispasmodic.<br>References Greenwood, B., et al.: Eur. J. Pharmacol., 211, 143 (1992), van Outryve, M., et al.: J. Clin. Pharm. Ther., 20, 277 (1995), Kraemer, T., et al.: Drug Metab. Disp., 28, 339 (2000),<br></p>Fórmula:C16H27NO2Forma y color:NeatPeso molecular:265.39Ref: 10-F505379
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarOSI-420, Free Base (Desmethyl Erlotinib)
CAS:Producto controladoFórmula:C21H21N3O4Forma y color:NeatPeso molecular:379.41Ofloxacin
CAS:<p>Applications Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);<br></p>Fórmula:C18H20FN3O4Forma y color:Off-WhitePeso molecular:361.37Argatroban Ethyl Ester
Producto controladoFórmula:C25H40N6O5SForma y color:NeatPeso molecular:536.687Diclazuril
CAS:<p>Applications Nucleotide analog with broad-spectrum anticoccidial activity. Coccidiostat.<br>References Maes, L., et al.: J. Parasitol., 74, 931 (1988);<br></p>Fórmula:C17H9Cl3N4O2Forma y color:Off-WhitePeso molecular:407.64Diclazuril 6-Carboxamide
CAS:Producto controlado<p>Applications Diclazuril 6-Carboxamide is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br></p>Fórmula:C18H10Cl3N5O3Forma y color:NeatPeso molecular:450.665-Chloro-3-(4-chloro-phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde
CAS:Pureza:95.0%Peso molecular:317.17001342773443,6-Diiodo-1H-indazole
CAS:Producto controlado<p>Applications 3,6-Diiodo-1H-indazole is used to prepare aryl-substituted indazole derivatives as modulators and inhibitors of protein kinases in the treatment of tumor growth, cellular proliferation, and angiogenesis.<br>References Kania, R., et al.: PCT Int. Appl., WO 2001002369 A2 20010111 (2001)<br></p>Fórmula:C7H4I2N2Forma y color:NeatPeso molecular:369.932-(2-thienylcarbonyl)-1,2,3,4-tetrahydroisoquinolin-7-amine
CAS:Pureza:95.0%Peso molecular:258.3399963378906(S)-2-(((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)(nitroso)amino)-3-methylbutanoic Acid
CAS:Producto controladoFórmula:C19H20N6O3Forma y color:Light YellowPeso molecular:380.4rac-cis-7-Hydroxy Pramipexole
CAS:Producto controlado<p>Impurity Pramipexole Related Compound G<br>Applications Pramipexole derivative used for the preparation of (S)-Pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives.<br>References Validation of a column liquid chromatographic method for the analysis of pramipexole and its 5 impurities. Journal of AOAC International (2010), 93(4), 1102-1112. Gegoe, Csaba Lehel; Fejes, Imre; Garaczi, Sandor; Kovacs, Imre; Lukacs, Ferenc; Majercsik, Orsolya; Schneider, Geza. Process for preparation of (S)-pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives. Eur. Pat. Appl. (2008), 26pp. CODEN: EPXXDW EP 1878731<br></p>Fórmula:C10H17N3OSForma y color:NeatPeso molecular:227.336-Amino-1,3-dimethyluracil
CAS:Producto controlado<p>Applications 6-Amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. It is also used as a starting material in the synthesis of fused pyrido-pyrimidines.<br>References Abu-Hashem, A., et al.: Lett. Drug. Des. Discov., 12, 471 (2015); Azev, Y., et al.: Mendeleev Commun., 25, 310 (2015)<br></p>Fórmula:C6H9N3O2Forma y color:Light YellowPeso molecular:155.1510H-Phenothiazine 5-Oxide
CAS:<p>Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.<br>References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)<br></p>Fórmula:C12H9NOSForma y color:Light Beige To Light BrownPeso molecular:215.272-(Piperazin-1-yl)acetic acid N-(3-pyridyl)amide trihydrochloride
CAS:Fórmula:C11H19Cl3N4OPureza:97.0%Forma y color:SolidPeso molecular:329.653-Chloro-1,2-propanediol-d5
CAS:Producto controladoFórmula:C32H5H2ClO2Forma y color:ColourlessPeso molecular:115.571-(3-Carboxypropyl)-3,7-dimethylxanthine
CAS:Producto controlado<p>Applications A metabolite of Pentoxifylline (P276500).<br>References Yamaoka, K., et al.: J. Pharmacokin. Biopharm., 6, 165 (1978), Cottam, H.B., et al.: J. Med. Chem., 39, 2 (1996), Janvilisri, T., et al.: J. Biol. Chem., 278, 20645 (2003),<br></p>Fórmula:C11H14N4O4Forma y color:NeatPeso molecular:266.25Rilpivirine HCl
CAS:Rilpivirine HCl (Rilpivirine hydrochloride) is an NNRTI inhibitor with antiviral activity that inhibits the HIV virus.Fórmula:C22H19ClN6Pureza:99.48%Forma y color:SolidPeso molecular:402.88
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