Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65624 productos de "Derivados de Quinazolina y Quinolina"
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Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate
CAS:<p>Applications Methyl 2-Methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate is a nicardipine impurity. Also, it is derived from Methyl Acetoacetate (O848425), which is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Vaghela, B. K., et al.: J. Liq. Chromatogr. Related Technol., 36, 2166-2181 (2013);<br></p>Fórmula:C15H15NO5·C16H17NO5Forma y color:NeatPeso molecular:592.59N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Producto controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Forma y color:NeatPeso molecular:425.43Blonanserin-d5
CAS:Producto controlado<p>Applications Labelled Blonanserin (B595850). A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.<br>References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),<br></p>Fórmula:C23H25D5FN3Forma y color:NeatPeso molecular:372.53Olaquindox
CAS:<p>Applications A growth stimulant.<br>References Barber, R.S., et al.: Anim. Feed Sci. Technol., 4, 117 (1979), Kwaga, J., et al.: Antimicrob. Agents Chemother., 34, 2423 (1990), Hugot, J., et al.: Lancet, 362, 2012 (2003),<br></p>Fórmula:C12H13N3O4Forma y color:NeatPeso molecular:263.254-Chloro-2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine
CAS:Pureza:95%Peso molecular:266.760009765625Nadifloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial (topical).<br>References Kurokawa, I., et al.: J. Am. Acad. Dermatol., 25, 674 (1991),<br></p>Fórmula:C19H21FN2O4Forma y color:White To Off-WhitePeso molecular:360.38Everolimus
CAS:Producto controlado<p>Impurity Everolimus EP Impurity C<br>Stability Hygroscopic<br>Applications Everolimus Macrolide immunosuppressant; Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C53H83NO14Pureza:~90%Forma y color:NeatPeso molecular:958.22Olanzapine
CAS:Producto controlado<p>Applications Olanzapine is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Neuroprotective product.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H20N4SForma y color:Light Yellow CrystallinePeso molecular:312.433-[[[2-[(Diaminomethylene]amino-4-thiazolyl]thio]propionitrile
CAS:Producto controladoFórmula:C8H11N5S2Forma y color:NeatPeso molecular:241.344-phenyl-3-(2-thienyl)-1,2,4-triazoline-5-thione 98%
CAS:Pureza:98.0%Peso molecular:259.35000610351563-(3-([1,1'-biphenyl]-4-yl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid
CAS:Pureza:97%Peso molecular:366.422-Methoxy Phenothiazine
CAS:<p>Applications An impurity of Methotrimeprazine (M260785).A derivative of Phenothiazine (P318040) exhibits tuberculostatic activity.<br>References Waisser, K., et al.: Folia. Pharm. Univ. Carol., 18, 41 (1995)<br></p>Fórmula:C13H11NOSForma y color:Grey To BrownPeso molecular:229.305-p-Tolyl-1H-pyrazole-3-carboxylic acid methyl ester
CAS:Pureza:95.0%Peso molecular:216.24000549316406Loxapine-d8 Hydrochloride (Major)
CAS:Producto controladoFórmula:C18H10D8ClN3O·xHClForma y color:White To Off-WhitePeso molecular:372.32ETHYL 2-(3-METHYL-4-OXO-3,4-DIHYDROPHTHALAZIN-1-YL)ACETATE
CAS:Pureza:95.0%Peso molecular:246.26600646972656Ref: 10-F505729
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar6-Bromo-2-phenylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:328.16500854492193-(5-azetidin-3-yl-1,2,4-oxadiazol-3-yl)pyridine dihydrochloride
CAS:Pureza:95.0%Peso molecular:275.13000488281253-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Forma y color:NeatPeso molecular:252.276-Des(1-methyl-2-benzimidazolyl)-6-carboxy Telmisartan
CAS:Producto controlado<p>Impurity Telmisartan EP Impurity E / Telmisartan Diacid<br>Applications An impurity of Telmisartan (T017000).<br>References Yu, W. et al.: Youji Huaxue, 26, 318 (2006);<br></p>Fórmula:C26H24N2O4Forma y color:NeatPeso molecular:428.49N-(2-chloro-4-methylpyridin-3-yl)-2-(cyclopropylamino)nicotinamide
CAS:Pureza:98%Peso molecular:302.7600097656255-Imino-N,4-bis(4-phenyl)-4,5-dihydro Riluzole
Producto controladoFórmula:C16H10F6N4O2SForma y color:NeatPeso molecular:436.334-Chloro Loratadine
CAS:<p>Impurity Loratadine EP Impurity C<br>Applications 4-Chloro Loratadine (Loratadine EP Impurity C) is an impurity of Loratadine (L469575).<br>References Zhong, D., et al.: Pharmazie, 49, 736 (1994), Squella, J., et al.: Talanta, 43, 2029 (1996), Ruperez, F., et al.: J. Pharm. Biomed. Anal., 29, 35 (2002),<br></p>Fórmula:C22H22Cl2N2O2Forma y color:WhitePeso molecular:417.33S-[5-Chloro-3-(trifluoromethyl)pyrid-2-yl]-S-methylsulfilimine 2,4,6-trimethylbenzenesulfonate
CAS:Fórmula:C16H18ClF3N2O3S2Pureza:95.0%Peso molecular:442.94-Pyrazol-1-ylmethyl-phenylamine
CAS:Fórmula:C10H11N3Pureza:98%Forma y color:SolidPeso molecular:173.219Bupivacaine-d9 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Bupivacaine (B689560). Sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Fórmula:C182H9H19N2O·ClHForma y color:NeatPeso molecular:333.944-Amino-3,5-dichloropyridine
CAS:<p>Applications 4-Amino-3,5-dichloropyridine is a metabolite of the selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br>References Jeffrey, A.D. et al.: Drug Chem. Toxicol., 25, 93 (2002); Cassidy, K.C. et al.: J. Pharmac. Biomed. Anal., 22, 869 (2000);<br></p>Fórmula:C5H4Cl2N2Forma y color:NeatPeso molecular:163.0A77 1726-d4
CAS:Producto controlado<p>Applications The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Fórmula:C122H4H5F3N2O2Forma y color:Off-WhitePeso molecular:274.23Hydroxy Flutamide
CAS:Producto controlado<p>Applications The active metabolite of the widely used non-steroidal antagonist Flutamide (F598850). Shown to be an antianhydrogen.<br>References Katchen, B., et al.: J. Clin. Endocrinol. Metab., 41, 373 (1975), Fau, D., et al.: J. Pharmacol. Exp. Ther., 269, 954 (1994), Anzenbacher, P., et al.: Drug Metab. Dispos., 30, 100 (2002), Norlin, M., et al.: J. Lipid Res., 43, 721 (2002),<br></p>Fórmula:C11H11F3N2O4Forma y color:Off White SolidPeso molecular:292.213-Methyl-1-phenyl-1H-pyrazole-5-carboxylic acid
CAS:Fórmula:C11H10N2O2Pureza:98%Forma y color:SolidPeso molecular:202.2134-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C15H17N3O2SForma y color:White To Light YellowPeso molecular:303.38Sibutramine, Hydrochloride Monohydrate
CAS:Producto controladoFórmula:C17H26ClN·ClH·H2OForma y color:Off White SolidPeso molecular:334.322-CHLORO-6-PYRIDINESULFONYL CHLORIDE
CAS:Fórmula:C5H3Cl2NO2SPureza:97%Forma y color:SolidPeso molecular:212.041-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine
CAS:Producto controlado<p>Applications 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents.<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012)<br></p>Fórmula:C14H18N4Forma y color:NeatPeso molecular:242.32N-Benzoyl-DL-tyrosyl-N',N'-dipropylamide
CAS:Producto controlado<p>Applications N-Benzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity C.<br>References Setnikar, I. et al.: Arzneim.-Forsch., 39, 328 (1989);<br></p>Fórmula:C22H28N2O3Forma y color:Off-WhitePeso molecular:368.474-Phenyl-2-(4-pyridyl)thiazole-5-carboxylic acid
CAS:Forma y color:SolidPeso molecular:282.32000732421875Prochlorperazine
CAS:Producto controlado<p>Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.<br>References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),<br></p>Fórmula:C20H24ClN3SForma y color:YellowPeso molecular:373.94Maropitant Citrate Salt
CAS:<p>Applications Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.<br>References Boscan, P. et al.: Am. J. Vet. Res., 72, 1576 (2011);<br></p>Fórmula:C32H40N2O·C6H8O7Forma y color:Off White SolidPeso molecular:660.8
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