Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65624 productos de "Derivados de Quinazolina y Quinolina"
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Tadalafil-d3
CAS:Producto controlado<p>Stability Unstable in Methanol<br>Applications Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),<br></p>Fórmula:C222H3H16N3O4Forma y color:White SolidPeso molecular:392.422-Methoxynaphthalene
CAS:Producto controlado<p>Impurity Naproxen EP Impurity M<br>Applications 2-Methoxynaphthalene is an impurity of the non-steroidal anti-inflammatory Naproxen (N377525).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Castelli, F. et al.: Int. J. Phamac., 184, 21 (1999); Dong, X. et al.: Hun. Huag., 29, 59 (1999);<br></p>Fórmula:C11H10OForma y color:White To Off-WhitePeso molecular:158.20Tazarotene Thiochromane Dimer
CAS:<p>Applications Tazarotene Thiochromane DImer is an impurity of Tazarotene (T010050), an acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C26H26S2Forma y color:NeatPeso molecular:402.6146Valsartan Ethyl Ester
CAS:Producto controlado<p>Applications Valsartan Ethyl Ester is an impurity of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C26H33N5O3Forma y color:White To Light BeigePeso molecular:463.57Cobicistat
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Cobicistat is a HIV protease inhibitor and has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations.<br>References Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012); Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012); Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012);<br></p>Fórmula:C40H53N7O5S2Forma y color:NeatPeso molecular:776.02Methomyl
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Methomyl is a carbamate insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Armes, N., et al.: Bull. Entomol. Res., 86, 499 (1996); Shono, T., et al.: Pest. Biochem. Physiol., 75, 1 (2003)<br></p>Fórmula:C5H10N2O2SForma y color:ColourlessPeso molecular:162.21rac-5-Bromo Naproxen
CAS:Producto controladoFórmula:C14H13BrO3Forma y color:NeatPeso molecular:309.164-(furan-2-yl)-6-(5-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:257.309997558593752-(3,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS:Pureza:97.0%Peso molecular:329.19000244140625Genfatinib-d3 (Imatinib-d3)
CAS:Producto controlado<p>Applications Genfatinib-d3 (Imatinib-d3) is the labeled analogue of Genfatinib, a treatment of chronic myeloid leukemia (CML). It is a COVID19-related research product.<br>References Helmann, R., et. al.: J. Clin. Oncol., 32, 415 (2014)<br></p>Fórmula:C29D3H28N7OForma y color:NeatPeso molecular:496.622-Hydroxymethyl Loratadine
CAS:Producto controlado<p>Impurity Loratadine 2-Hydroxymethyl Impurity (USP)<br>Applications A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP).<br>References Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959), Eyjolfsson, R., et al.: Pharmazie, 58, 154 (2003),<br></p>Fórmula:C23H25ClN2O3Forma y color:NeatPeso molecular:412.91(S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid
CAS:Pureza:95.0%Peso molecular:296.3229980468754,7-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.3699951171875Mequitazine
CAS:Producto controlado<p>Applications It is an antihistamine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Uzan, A., et al.: Xenobiotica, 6, 633 (1976), Persi, L., et al.: Alergy, 52, 451 (1997), Nakamura, K., et al.: J. Pharmacol. Exp. Ther., 284, 437 (1998), Theunissen, E., et al.: Clin. Exp. Allergy, 34, 250 (2004),<br></p>Fórmula:C20H22N2SForma y color:NeatPeso molecular:322.471-Phenyl-3-(5,6,7,8-tetrahydronaphthalen-2-yl)-1h-pyrazol-5-amine
CAS:Pureza:97%Peso molecular:289.3819885253906Levofloxacin Ethyl Ester
CAS:Producto controlado<p>Impurity Levofloxacin USP Related Compound C<br>Applications Levofloxacin Ethyl Ester (Levofloxacin USP Related Compound C) is an impurity of Levofloxacin (L360000).<br>References Lalitha Devi, M. et al.: J. Pharrm. Biomed. ANal., 50, 710 (2009); Mehta, J. et al.: Int. J. PharmTech Res., 2, 1932 (2010);<br></p>Fórmula:C20H24FN3O4Forma y color:White To Off-WhitePeso molecular:389.423-Picoline
CAS:Producto controlado<p>Applications A useful precursor to agrochemicals and antidotes for organophosphate poisoning.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Qiao, L., et al.: Bioorg. Med. Chem. Lett., 19, 6122 (2009), Giri, A., et al.: Food Chem., 120, 621 (2010), Farrer, N., et al.: Chem. Res. Toxicol., 23, 413 (2010),<br></p>Fórmula:C6H7NForma y color:ColourlessPeso molecular:93.13tau-Fluvalinate (Mixture of Diastereomers)
CAS:<p>Applications τ-Fluvalinate is a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Delaplane, K.S. et al.: J. Econ. Entomol., 88, 1206 (1995); Ferrer-Dufol, M. et al.: J. Apicul. Res., 34, 147 (1995); Lindberg, C.M. et al.: J. Econ. Entomol., 93, 189 (2000);<br></p>Fórmula:C26H22ClF3N2O3Forma y color:Light YellowPeso molecular:502.911-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:309.32101440429693,5,6-Trihydroxy-1-isopropylindole
CAS:Producto controlado<p>Applications 3,5,6-Trihydroxy-1-isopropylindole is an impurity of Isoproterenol (I874200), which is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.<br>References Kikkawa, H. et al.: Biol. Pharmac. Bull., 17, 1047 (1994); Kral, P. et al.: Psychopharmacologia, 26, 79 (1972); Giles, R.E. et al.: J. Pharmacol. Exp. Ther., 186, 472 (1973);<br></p>Fórmula:C11H13NO3Forma y color:NeatPeso molecular:207.226(2R)-2-Hydroxy-N-[2-(4-nitrophenyl)ethyl]-2-phenylacetamide
CAS:Fórmula:C16H16N2O4Forma y color:NeatPeso molecular:300.31(2-CHLOROPYRIDIN-4-YL)(1H-PYRROLO[3,2-C]PYRIDIN-3-YL)METHANONE
CAS:Pureza:95.0%Peso molecular:257.67999267578125Regorafenib-d3
CAS:Producto controlado<p>Applications Regorafenib-d3 is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)<br></p>Fórmula:C21H12D3ClF4N4O3Forma y color:NeatPeso molecular:485.83N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe
CAS:Fórmula:C24H21F2NO3Forma y color:Off White SolidPeso molecular:409.432-Methyl-Celecoxib
CAS:Producto controlado<p>Impurity 2,4-Dimethyl Celecoxib Impurity<br>Applications 2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C18H16F3N3O2SForma y color:Off-White To BeigePeso molecular:395.47-Nitro-4-(pyridin-2-ylmethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
CAS:Pureza:95+%Peso molecular:285.2590026855469Ref: 10-F608382
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarSodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:97%Peso molecular:405.3500061035156cis-Tadalafil
CAS:Producto controlado<p>Impurity Tadalafil EP Impurity A<br>Applications The (6R)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6R,12aS)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Fórmula:C22H19N3O4Forma y color:Off-WhitePeso molecular:389.40Celecoxib-d4
CAS:Producto controlado<p>Applications A labelled selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in the treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C17H10D4F3N3O2SForma y color:White To Light YellowPeso molecular:385.4Valsartan-d9 (Major)
CAS:Producto controlado<p>Applications An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C24H20D9N5O3Forma y color:Off WhitePeso molecular:444.574-fluoro-2-(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)aniline
CAS:Pureza:95.0%Peso molecular:256.2399902343752-[5-chloro-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:308.2099914550781Cyamemazine
CAS:<p>Applications Cyamemazine is an anxiolytic antipsychotic, which reduces ethanol withdrawal symptoms.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Robinson, et al.: J. Pharm. Pharmacol., 18, 19 (1966), Miller, L., et al.: J. Pharmacol. Exp. Ther., 246, 170 (1988), Podhorna, J., et al.: Curr. Pharm. Des., 8, 23 (2002), Hameg, A., et al.: Biochem. Pharmacol., 65, 435 (2003),<br></p>Fórmula:C19H21N3SForma y color:Green YellowPeso molecular:323.464-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxy-benzamide
CAS:<p>Impurity Amisulpride EP Impurity C<br>Applications 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxy-benzamide is an impurity of Amisulpride (A633250), an antipsychotic. Amisulpride is a dopamine receptor antagonist. (Amisulpride EP Impurity C). Dopamine imaging agent<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Fórmula:C15H22IN3O2Forma y color:NeatPeso molecular:403.26Ketoconazole-d8
CAS:Producto controlado<p>Applications Deuterated Ketoconazole, an inhibitor of cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Fórmula:C26H20D8Cl2N4O4Forma y color:White To BeigePeso molecular:539.48Tert-Butyl 1-oxo-4-(pyridin-3-yl)-2,8-diazaspiro[4.5]decane-8-carboxylate
CAS:Pureza:98%Peso molecular:331.4159851074219Amantadine
CAS:Producto controlado<p>Applications Amantadine is useful in biology studies. Particularly it has been used for solid-state NMR and membrane protein studies.<br>References Shigeta, A., et al.: New Developments in NMR, 20, 457 (2019)<br></p>Fórmula:C10H17NForma y color:White To Off-WhitePeso molecular:151.256-chloro-2-(4-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.739990234375Amisulpride-d5 N-Oxide
CAS:Producto controlado<p>Applications Labelled Amisulpride N-Oxide (A633265). Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride.<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Fórmula:C17H22D5N3O5SForma y color:WhitePeso molecular:390.51Riociguat
CAS:Producto controlado<p>Applications Riociguat is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C20H19FN8O2Forma y color:NeatPeso molecular:422.4157(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
CAS:Pureza:97%Forma y color:SolidPeso molecular:428.512-Methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS:Producto controladoFórmula:C11H12F3NOForma y color:NeatPeso molecular:231.21
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