Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65624 productos de "Derivados de Quinazolina y Quinolina"
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Tert-Butyl (R)-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)carbamate
CAS:Pureza:95%Peso molecular:409.48599243164068-[2-(Diphenylmethoxy)-N-methylethylamino]-1,3-dimethylxanthine
CAS:<p>Applications 8-[2-(Diphenylmethoxy)-N-methylethylamino]-1,3-dimethylxanthine is an impurity of Dimenhydrinate (D460520), an antihistamine with antiemetic properties used to prevent nausea and motion sicknes composed of two drugs 8-Chlorotheophylline (C411440) and Diphenhydramine (D486900).<br>References Doege, U., et al.: Pharmazie., 62, 174 (2007); Santoro, R.S., et al.: J. Pharmaceut. Sci., 60, 791 (1971);<br></p>Fórmula:C23H25N5O3Forma y color:White To Off-WhitePeso molecular:419.48ETHYL 1-METHYL-3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLATE
CAS:Pureza:97.0%Peso molecular:298.26501464843754-(Methylsulfonyl)phenylacetic Acid
CAS:Producto controlado<p>Applications 4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.<br>References Eren, G., et al.: Bioorg. Med. Chem., 18, 6467 (2010); Weber, V., et al.: Bioorg. Med. Chem., 13, 4552 (2005)<br></p>Fórmula:C9H10O4SForma y color:NeatPeso molecular:214.242-Ethyl-2-methylsuccinic Acid
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 2-Ethyl-2-methylsuccinic Acid is an inhibitor of plasmid-borne IMP-1 metallo-β-lactamase.<br>References Toney, J., et. al.: J. Biol. Chem., 276, 31913 (2001)<br></p>Fórmula:C7H12O4Forma y color:NeatPeso molecular:160.1682-Hydroxy-6-methylpyridine-3,4-dicarboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:197.14599609375Ranitidine-d6 Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.<br>References Bradshaw, J., et al.: Brit. J. Pharmacol., 66, 464 (1979), Berstad, A., et al.: Scand. J. Gastroenterol, 15, 637 (1980), Hohnjec, M., et al.: Anal. Profiles Drug Subs., 15, 533 (1986),<br></p>Fórmula:C132H6H16N4O3S·ClHPureza:>90%Forma y color:NeatPeso molecular:356.902,6-Dimethyl-quinoline-3-carboxylic acid
CAS:Fórmula:C12H11NO2Pureza:95.0%Forma y color:SolidPeso molecular:201.225Potassium Phthalimide
CAS:Producto controlado<p>Applications Potassium Phthalimide is a green, solid-base organocatalys.<br>References Kiyani, H., Ghiasi, M.: Chinese Chem. Lett., 25, 313 (2014)<br></p>Fórmula:C8H4NO2·KForma y color:NeatPeso molecular:185.222-(1-phenyl-1H-pyrazol-4-yl)cyclopropane-1-carboxylic acid
CAS:Pureza:95.0%Peso molecular:228.25100708007812Acetohydrazide
CAS:Producto controlado<p>Applications Acetohydrazide is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metushi, I.G., et al.: Chem. Res. Toxciol., 25, 2567 (2012); Fukino, K., et al.: J. Toxicol. Sci., 33, 667 (2008);<br></p>Fórmula:C2H6N2OForma y color:Off-WhitePeso molecular:74.084-Dechloro-4-hydroxy Diclazuril
CAS:<p>Applications 4-Dechloro-4-hydroxy Diclazuril is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br>References Fodey, T.L., et al.: J. Immunol. Meth., 323, 31 (2007);<br></p>Fórmula:C17H10Cl2N4O3Forma y color:NeatPeso molecular:389.19Empagliflozin R/S-Furanose
CAS:<p>Applications Empagliflozin R/S-Furanose is a mixture of R and S isomers of Empagliflozin Furanose. Both are byproducts in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012); Wang, X., et al.: Org. Lett., 16, 4090 (2014);<br></p>Fórmula:C23H27ClO7Forma y color:White To Off-WhitePeso molecular:450.909Acetyl Isoniazid-d4
CAS:Producto controlado<p>Applications A labelled metabolite of Isoniazid (I821450) in plasma.<br>References Peloquin, C., et al.: Antimicrob. Agents Chemother., 41, 2670 (1997), Peloquin, C., et al.: Drugs, 62, 2169 (2002),<br></p>Fórmula:C8H5D4N3O2Forma y color:Off-WhitePeso molecular:183.23-(1-benzofuran-2-yl)-1H-pyrazole
CAS:Pureza:95.0%Forma y color:Solid, Beige powderPeso molecular:184.197998046875Aripiprazole Hydrate
CAS:Producto controlado<p>Applications Aripiprazole Hydrate is an agonist at the dopamine autoreceptor and an antagonist at the postsynaptic D2 receptor (1,2,3,4). Aripiprazole is an antipsychotic and a potential drug candidate for treating psychoses such as schizophrenia.<br>References Pan, B., et al.: Psychopharmacology, PagesAhead of Print( 2019), Kim, J. Y., et al.: Anticancer Res., 38, 5101 (2018)<br></p>Fórmula:C23H27Cl2N3O2·xH2OForma y color:NeatPeso molecular:448.39 + 36.022-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Fórmula:C2H3BrO2Forma y color:Light YellowPeso molecular:138.95Famotidine-d4 (Major)
CAS:Producto controlado<p>Applications Famotidine-d4 is the labeled analogue of Famotidine (F102250), a histamine H2-receptor antagonist. Antiulcerative.<br>References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982); Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984); Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985)<br></p>Fórmula:C8H11D4N7O2S3Forma y color:NeatPeso molecular:341.476-Benzyloxy-7-methoxy-2-methyl-quinoline-3-carboxylic acid
Pureza:95.0%Peso molecular:323.3479919433594Dothiepin-d3
CAS:Producto controlado<p>Stability Temperature Sensitive<br>Applications Labelled Dothiepin (D536500). A tricyclic antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Metysova, J., et al.: Arzneim.-Forsch., 13, 1039 (1963), Maguire, K.P., et al.: Br. J. Clin. Pharmacol., 12, 405 (1981), Donovan, S., et al.: Prog. Neuro-Psychopharmacol. Biol. Psychiatry, 18, 1143 (1994),<br></p>Fórmula:C19H18D3NSForma y color:NeatPeso molecular:298.464-(4-Amino-3-chlorophenoxy)-7-methoxyquinoline-6-carboxamide
CAS:Pureza:97%Peso molecular:343.7699890136719Norneo Vardenafil
CAS:Producto controlado<p>Applications Norneo Vardenafil is a related compound of Vardenafil (V098001) as phosphodiesterase inhibitor.<br></p>Fórmula:C18H20N4O4Forma y color:Off White SolidPeso molecular:356.38Ethyl 2-[6-(formamidomethyl)-3-phenyl-2-pyridyl]acetate
CAS:Pureza:97%Peso molecular:298.3420104980469Ref: 10-F625998
1gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultar4-methoxy-7-methyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:285.3699951171875rac-Monepantel
CAS:Producto controlado<p>Applications rac-Monepantel is a recently discovered anthelmitic used in the treatment of parasitic nematodes via stun or kill without damaging the host entity.<br>References Baur, R. et al.: Mol. Pharm., 87, 96 (2015); Stuchlikova, L. et al.: Chemico. Biol. Interact., 227, 63 (2015);<br></p>Fórmula:C20H13F6N3O2SForma y color:Off White SolidPeso molecular:473.392-[3-(4-nitrophenyl)-1-phenyl-1h-pyrazol-4-yl]acetic acid
CAS:Pureza:97%Peso molecular:323.3080139160156Sodium 2-(6-methylpyridin-2-yl)acetate
CAS:Pureza:95.0%Forma y color:Solid, Grey powderPeso molecular:173.147003173828124-(1-Pyrrolidinylsulforylmenthyl)phenylhydrazine Hydrochloride
CAS:Producto controlado<p>Applications Intermediate in the preparation of Almotriptan.<br></p>Fórmula:C11H18ClN3O2SForma y color:NeatPeso molecular:291.8Ref: 10-F505686
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarBrexpiprazole
CAS:Producto controlado<p>Applications Brexpiprazole is a drug candidate useful in treatment and prevention of mental disorders including CNS disorders.<br>References Yamashita, H., et al.: PCT Int. Appl., WO 2006112464 A1 20061026 (2006);<br></p>Fórmula:C25H27N3O2SForma y color:White To Light BrownPeso molecular:433.57Nilotinib-d3
CAS:Producto controlado<p>Applications Labelled analog of Nilotinib (AMN1O7), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Fórmula:C282H3H19F3N7OForma y color:Off-White To Light YellowPeso molecular:532.53(S)-a,a-Diphenyl-3-pyrrolidineacetamide L-Tartrate
CAS:Producto controladoFórmula:C18H20N2O·C4H6O6Forma y color:NeatPeso molecular:430.455-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:232.195007324218751,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS:Producto controlado<p>Applications A carvedilol Impurity.<br></p>Fórmula:C27H22N2O3Forma y color:NeatPeso molecular:422.48p-Nicorandil
CAS:<p>Applications A positional isomeric impurity of the antianginal Nicorandil (N398500).<br>References Fedorov, B.S. et al.: Pharmac. Chem. J., 43, 134 (2009); Tatyanenko, L.V. et al.: Biomed. Khim., 52, 174 (2006);<br></p>Fórmula:C8H9N3O4Forma y color:BeigePeso molecular:211.173-(2-Methoxyphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS:Pureza:98%Peso molecular:294.309997558593755-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
CAS:Pureza:95.0%Peso molecular:367.3699951171875Tranilast
CAS:Producto controlado<p>Applications Antiallergic drug, used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.<br>References Shiota, N., et al.: Brit. J. Pharmacol., 159, 626 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Kawabata, Y., et al.: Eur. J. Pharm. Sci., 39, 256 (2010),<br></p>Fórmula:C18H17NO5Forma y color:NeatPeso molecular:327.33
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