Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65576 productos de "Derivados de Quinazolina y Quinolina"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
N-Formyl Oxcarbazepine
CAS:Producto controlado<p>Applications N-Formyl Oxcarbazepine is an impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Fórmula:C16H12N2O3Forma y color:NeatPeso molecular:280.28Cinnarizine
CAS:<p>Applications Calcium channel blocker with antiallergic and anti-vasoconstricting activity. Antihistaminic.<br>References Barber, J.H., et al.: Pharmatherapeutica, 2, 401 (1980), Spedding, M., et al.: Arch. Pharmacol., 318, 234 (1982), Morad, et al.: Pharmacol. Res., 35, 177 (1997)<br></p>Fórmula:C26H28N2Forma y color:NeatPeso molecular:368.51Omeprazole Sulfide
CAS:Producto controladoFórmula:C17H19N3O2SForma y color:White To Light BrownPeso molecular:329.423-(1,3-benzodioxol-5-yl)-1-methyl-1{H}-pyrazole-5-carboxylic acid
CAS:Pureza:95.0%Peso molecular:246.2220001220703(S)-Mephenytoin
CAS:<p>Applications An anticonvulsant agent.<br>References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),<br></p>Fórmula:C12H14N2O2Forma y color:Off-WhitePeso molecular:218.25Rivastigmine Tartrate Salt
CAS:Producto controladoFórmula:C14H22N2O2·C4H6O6Forma y color:White To Off-WhitePeso molecular:400.42MDV 3100-d3
CAS:Producto controlado<p>Applications Labelled MDV 3100. MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Fórmula:C21H13D3F4N4O2SForma y color:NeatPeso molecular:467.45Ticagrelor Amine Derivative
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Ticagrelor Amine Derivative is a metabolite of Ticagrelor (T437700). Ticagrelor is a reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C23H29F2N7O3SForma y color:White To Off-WhitePeso molecular:521.583,4-Dihydro Naratriptan Oxalate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Fórmula:C17H23N3O2S·C2H2O4Forma y color:White To Light YellowPeso molecular:333.45 + 90.03Ticagrelor-d7
CAS:Producto controlado<p>Applications Labelled Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Fórmula:C232H7H21F2N6O4SForma y color:YellowPeso molecular:529.612,5-Bis(2-hexyldecyl)-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Pureza:99%Peso molecular:749.21002197265621,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline
CAS:<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-1)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Fórmula:C10H13NO2Forma y color:White To Light YellowPeso molecular:179.22Racecadotril
CAS:Producto controlado<p>Applications Antidiarrheal; enkephalinase inhibitor, reducing the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),<br></p>Fórmula:C21H23NO4SForma y color:NeatPeso molecular:385.48C -(4-Chloro-2-ethyl-2 H -pyrazol-3-yl)-methylamine
CAS:Fórmula:C6H10ClN3Pureza:98%Forma y color:SolidPeso molecular:159.62Ranolazine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Ranolazine Dihydrochloride is an anti-ischemic agent which modulates myocardial metabolism. Antianginal.<br>References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004); McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998); Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002)<br></p>Fórmula:C24H35Cl2N3O4Forma y color:NeatPeso molecular:500.462-chloro-6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazoline
CAS:Pureza:97.0%Peso molecular:369.6300048828125Ref: 10-F519250
1gA consultar5gA consultar10gA consultar25gA consultar100mgA consultar250mgA consultar500mgA consultarN-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine
CAS:Producto controlado<p>Applications N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.<br></p>Fórmula:C19H16N2O5Forma y color:NeatPeso molecular:352.342-(4-Methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid
CAS:Pureza:97%Peso molecular:295.294006347656253’-Acetyl-4’-(2,3-epoxypropoxy)butyranilide
CAS:<p>Impurity Acebutolol EP Impurity A<br>Applications 3’-Acetyl-4’-(2,3-epoxypropoxy)butyranilide (Acebutolol EP Impurity A) is a useful intermediate in the preparation of Acebutolol.<br>References Andresen, B., et al.: Drug Metab. Disposition, 7, 360 (1979),<br></p>Fórmula:C15H19NO4Forma y color:Off-WhitePeso molecular:277.321-(4-Chlorophenyl)-5-(furan-2-yl)-1h-pyrazole-3-carboxylic acid
CAS:Pureza:95%Peso molecular:288.69000244140625Phenylephrone Hydrochloride
CAS:<p>Impurity Phenylephrine EP Impurity C; Phenylephrine USP Related Compound C (1-(3-Hydroxyphenyl)-2-(methylamin<br>Applications Phenylephrine Hydrochloride (Phenylephrine EP Impurity C; Phenylephrine USP Related Compound C (1-(3-Hydroxyphenyl)-2-(methylamino)ethan-1-one Hydrochloride)) is an impurity C of Phenylephrine.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988), Goskonda, V., et al.: J. Pharm. Sci., 88, 180 (1999),<br></p>Fórmula:C9H11NO2·ClHForma y color:Off-White To BeigePeso molecular:201.65Propylthiouracil-d5
CAS:Producto controlado<p>Applications Labelled antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Fórmula:C7H5D5N2OSForma y color:Off-WhitePeso molecular:175.267-(Diethylamino)-3-(thiophen-2-yl)-2H-chromen-2-one
CAS:Pureza:98% HPLC,TPeso molecular:299.3900146484375N-(3-Chloro-4-fluorophenyl)-N-(7-methoxy-6-nitroquinazolin-4-yl)acetamide
CAS:Pureza:97.0%Peso molecular:390.760009765625Benidipine 5-(1-Benzylpiperidin-3-yl)
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications Benidipine 5-(1-Benzylpiperidin-3-yl) is an impurity of Benidipine (B157500), a dihydropyridine calcium channel blocker. Antihypertensive.<br>References Suzuki, T., et al.: Cardiovasc. Drug Rev., 7, 25 (1989); Hirayama, N., et al.: Acta Crystallogr., C47, 458 (1991)<br></p>Fórmula:C39H44N4O6Forma y color:NeatPeso molecular:664.79Cilostazol-d11
CAS:Producto controlado<p>Applications A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Fórmula:C20H16D11N5O2Forma y color:NeatPeso molecular:380.52Aripiprazole-d8 (Butyl-d8)
CAS:Producto controladoFórmula:C232H8H19Cl2N3O2Forma y color:White To Off-WhitePeso molecular:456.433,4-Dehydro Cilostazol-d11
CAS:Producto controlado<p>Applications A labelled metabolite of Cilostazol.<br></p>Fórmula:C20H14D11N5O2Forma y color:NeatPeso molecular:378.51rac-Ruxolitinib-d9 (major)
CAS:Producto controlado<p>Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>Fórmula:C17H9D9N6Forma y color:White To Light YellowPeso molecular:315.42N-Nitrosometoprolol
CAS:<p>Applications N-Nitrosometoprolol is an N-nitroso derivative of rac Metoprolol(M338815), which is a β1 selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder. N-Nitrosometoprolol can be used to assess human and rat hepatocytes.<br>References McGourty, J.C., et al.: Br. J. Clin. Pharmacol. 20, 555 (1985); Lennard, M.S., et al.: Biochem. Pharmacol., 35, 2757 (1986); Martelli, A., In Vivo, 11, 189-194, (1997);<br></p>Fórmula:C15H24N2O4Forma y color:Colourless To Light YellowPeso molecular:296.36(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Pureza:95.0%Peso molecular:345.4200134277344rac-trans-Ambroxol-d5
CAS:Producto controlado<p>Applications A labelled metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C13H13D5Br2N2OForma y color:NeatPeso molecular:383.13Methyl 2-Sulfamoylbenzoate
CAS:<p>Applications Methyl 2-Sulfamoylbenzoate is a building block used in various synthetic preparations. It is also classified as a pollutant found in a municipal wastewater treatment plant.<br>References Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009);<br></p>Fórmula:C8H9NO4SForma y color:NeatPeso molecular:215.23
![2,5-Bis(2-hexyldecyl)-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF763029.webp&w=3840&q=75)
![N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH948180.webp&w=3840&q=75)
![(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF448256.webp&w=3840&q=75)
