Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65576 productos de "Derivados de Quinazolina y Quinolina"
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(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:Producto controladoFórmula:C19H18IN3OForma y color:White To Light YellowPeso molecular:431.275-azetidin-3-yl-3-(3-thienyl)-1,2,4-oxadiazole hydrochloride
CAS:Pureza:95.0%Peso molecular:243.7100067138672Telmisartan
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)<br></p>Fórmula:C33H30N4O2Forma y color:NeatPeso molecular:514.62Ombitasvir
CAS:Producto controlado<p>Applications Ombitasvir is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.<br>References Feld, J.J., et al.: New Eng. J. Med., 370, 1594 (2014); Lawitz, E., et al.: J. Hepatol., 57, 24 (2012); Afdhal, N., et al.: New England J. Med., 370, 1889 (2014)<br></p>Fórmula:C50H67N7O8Forma y color:NeatPeso molecular:894.114-Bromoquinoline-6-carbonitrile
CAS:Fórmula:C10H5BrN2Pureza:98%Forma y color:SolidPeso molecular:233.068Pericyazine
CAS:Producto controlado<p>Applications Psychotherapeutic phenothiazine. Antipsychotic.<br>References Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Kaye, J., et al.: Br. J. Clin. Pharmacol., 56, 569 (2003), Tschoner, A., et al.: Pharmacopsychiatry, 42, 29 (2009),<br></p>Fórmula:C21H23N3OSForma y color:Light Yellow To YellowPeso molecular:365.49Vadadustat
CAS:<p>Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.<br>References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);<br></p>Fórmula:C14H11ClN2O4Forma y color:BeigePeso molecular:306.702-(5-azetidin-3-yl-1,2,4-oxadiazol-3-yl)pyridine dihydrochloride
CAS:Pureza:95.0%Peso molecular:275.1300048828125Ref: 10-F214928
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarTert-Butyl 2-(pyridin-4-yl)acetate
CAS:Pureza:95.0%Forma y color:LiquidPeso molecular:193.24600219726562Ref: 10-F335907
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar3-Dehydroxy Salbutamol
CAS:Producto controlado<p>Impurity Levalbuterol USP Related Compound B; Salbutamol EP Impurity C<br>Applications 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C) is an isoprenaline based selective stimulants of β-adrenergic receptors in bronchial muscles.<br>References Hartley, D., et al.: Nature., 219, 5156 (1968);<br></p>Fórmula:C13H21NO2Forma y color:NeatPeso molecular:223.313-Ethyl-2-imine Meloxicam
CAS:Producto controlado<p>Applications Meloxicam (M216100) impurity.<br></p>Fórmula:C16H17N3O4S2Forma y color:Light YellowPeso molecular:379.452-Hydroxy-6-methyl-quinoline-4-carboxylic acid
CAS:Fórmula:C11H9NO3Pureza:95.0%Peso molecular:203.197Clozapine
CAS:Producto controlado<p>Applications An antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Fórmula:C18H19ClN4Forma y color:Off-WhitePeso molecular:326.82Oxcarbazepine-D4 (Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Fórmula:C152H4H8N2O2Forma y color:Light Orange Colour PowderPeso molecular:256.29Lenalidomide-d5
CAS:Producto controlado<p>Applications Lenalidomide-d5, is the labeled analogue of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide.<br>References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),<br></p>Fórmula:C13H8D5N3O3Forma y color:Off-WhitePeso molecular:264.29(S)-Thalidomide
CAS:<p>(S)-Thalidomide ((S)-(-)-Thalidomide) has anti-angiogenic activity and pro-apoptotic activity and can be used in the study of erythema nodosum in leprosy.</p>Fórmula:C13H10N2O4Pureza:99.89%Forma y color:NeedlesPeso molecular:258.237-Bromo-N-(1,3-dimethylpyrazol-4-yl)quinazolin-2-amine
CAS:Pureza:98%Peso molecular:318.17800903320313-Aminopiperidine-2,6-dione Hydrochloride
CAS:Producto controlado<p>Applications 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.<br>References Kronke, J., et al.: Nature 523, 183 (2015); Liu C., et al.: Faming Zhuanli Shenqing CN 105348257 A 20160224 (2016); Rao, R., et al. : PCT Int. Appl. WO 2016024286 A2 20160218 (2016)<br></p>Fórmula:C5H8N2O2·ClHForma y color:Off-WhitePeso molecular:164.590N-Desmethyl 8-Chloro-5H-dibenzo[b,e][1,4]diazepine Clozapine
CAS:Producto controlado<p>Impurity CLOZAPINE EP IMPURITY B<br>Applications N-Desmethyl 8-Chloro-5H-dibenzo[b,e][1,4]diazepine Clozapine is a Clozapine (C587500) impurity, an antipsychotic.<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Fórmula:C30H24Cl2N6Forma y color:NeatPeso molecular:539.46γ-Aminobutyric Acid
CAS:<p>Applications An important inhibitory neurotransmitter. The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.<br>References Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951), Gerlach, M., et al.: Brain Res., 741, 142 (1996), Choi, D., et al.: J Neurobiol 1992, 23, 1261<br></p>Fórmula:C4H9NO2Forma y color:NeatPeso molecular:103.124-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride
CAS:Producto controlado<p>Impurity Paroxetine EP Impurity G<br>Applications 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride (Paroxetine EP Impurity G) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),<br></p>Fórmula:C12H14FN·ClHForma y color:Light YellowPeso molecular:227.71Picloram
CAS:<p>Picloram (Tordon) is an auxin-type herbicide with carcinogenic properties, controlling herbaceous weeds and woody plants.</p>Fórmula:C6H3Cl3N2O2Pureza:99.74%Forma y color:White Powder Physical Description Fine Beige Crystals Or White Powder Odor Of Chlorine (Ntp 1992)Peso molecular:241.46Dolutegravir (0.1 mg/mL in Methanol)
CAS:Fórmula:C20H19F2N3O5Forma y color:ColourlessPeso molecular:419.381,5-Dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:167.16400146484375Ilaprazole
CAS:Producto controlado<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Fórmula:C19H18N4O2SForma y color:NeatPeso molecular:366.44Piperonylic Acid
CAS:Producto controlado<p>Applications Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.<br>References Schalk, M. et al.: Plant Physiol., 118, 209 (1998);<br></p>Fórmula:C8H6O4Forma y color:NeatPeso molecular:166.13(S)-Efavirenz
CAS:<p>Applications A nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995),<br></p>Fórmula:C14H9ClF3NO2Forma y color:NeatPeso molecular:315.68Ketanserin
CAS:<p>Applications An antihypertensive, with affinity for multiple GPCR receptors.<br>References Zhu, Y., et al.: Biol. Pharm. Bull., 32, 1173 (2009), Shen, K., et al.: J. Pharm. Pharmacol., 61, 517 (2009), Brea, J., et al.: Mol. Pharmacol., 75, 1380 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C22H22FN3O3Forma y color:NeatPeso molecular:395.43Anagliptin
CAS:Producto controlado<p>Applications Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.<br>References Ervinna, N., et al.: Endocrinology, 154, 1260 (2013); Furuta, S., et al.: Eur. J. Drug Metab. Ph., 38, 87 (2013)<br></p>Fórmula:C19H25N7O2Forma y color:NeatPeso molecular:383.45rac-cis-N-Desmethyl Sertraline-d4 Hydrochloride
CAS:Producto controlado<p>Applications A labelled metabolite of Sertraline. N-Desmethyl Sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.<br>References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)<br></p>Fórmula:C16H12D4Cl3NForma y color:NeatPeso molecular:332.695-(Naphthalen-2-yl)-1-phenyl-1H-pyrazole-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:314.3439941406253-(3-([1,1'-biphenyl]-4-yl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid
CAS:Pureza:97%Peso molecular:366.42Dasatinib Dimeric Impurity
CAS:Producto controladoFórmula:C36H34Cl2N12O2S2Forma y color:White To BeigePeso molecular:801.77(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid
CAS:Producto controlado<p>Impurity Ambrisentan Hydroxy Acid Impurity<br>Applications (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid is used in analytical studies for chiral discrimination of α-functionalized acids. Ambrisentan Hydroxy Acid Impurity<br>References Jain, N., et al.: Tetrahedron, 70, 4343 (2014)<br></p>Fórmula:C16H16O4Forma y color:NeatPeso molecular:272.30KAD-1229 Calcium Hydrate
CAS:Producto controladoFórmula:C19H24NO3·Ca·2H2OForma y color:NeatPeso molecular:704.91Irbesartan
CAS:Producto controlado<p>Applications An angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997), Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998), Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008), Ren, X., et al.: Pharmacol., 83, 80 (2009),<br></p>Fórmula:C25H28N6OForma y color:NeatPeso molecular:428.53
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