Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65541 productos de "Derivados de Quinazolina y Quinolina"
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Captopril Disulfide
CAS:<p>Impurity Captopril EP Impurity A<br>Applications Captopril Disulfide (Captopril EP Impurity A) is a metabolite of Captopril. A new antihypertensive agent.<br>References Sprague, P., et al.: Perspect. Drug Discovery Des., 3, 21 (1995), Cushman, D., et al.: Nat. Med., 5, 1110 (1999), Jacoby, E., et al.: Drug News Perspect., 16, 93 (2003), Lengauer, T., et al.: Drug Discovery Today, 9, 27 (2004),<br></p>Fórmula:C18H28N2O6S2Forma y color:WhitePeso molecular:432.55Ethyl Ethanesulfonate
CAS:Producto controlado<p>Applications Ethyl Ethanesulfonate is used as a reactant in stereoselective Friedel-Crafts alkylation reactions. Also used in the preparation of 1-alkyl-3-methylimidazolium alkanesulfonate ionic liquids.<br>References Stadler, D., Bach, T.: Chem. Asian J., 3, 272 (2008); Blesic, M., et al.: Phys. Chem. Chem. Phys., 11, 8939 (2009);<br></p>Fórmula:C4H10O3SForma y color:NeatPeso molecular:138.19rac 8,14-Dihydroxy Efavirenz-d4
CAS:Producto controlado<p>Applications A labelled metabolite of Efavirenz (E425000) (secondary metabolism).<br>References Gorski, J., et al.: Biochem. Pharmacol., 47, 1643 (1994), Desta, Z., et al.: J. Pharmacol. Exp. Ther., 285, 428 (1998), Langmann, P., et al.: Eur. J. Med. Res., 7, 309 (2002), Chang, T., et al.: Drug Metab. Dispos., 31, 7 (2003),<br></p>Fórmula:C14H5D4ClF3NO4Forma y color:NeatPeso molecular:351.70Eltenac
CAS:<p>Applications Eltenac is a nonsteroidal anti-inflammatory drug.<br>References Allen, A., et al.: Gut, 21, 249 (1980), Tobin, T., et al.: J. Vet. Pharmacol. Therap., 9, 1 (1986),<br></p>Fórmula:C12H9Cl2NO2SForma y color:NeatPeso molecular:302.18Pibrentasvir
CAS:Producto controlado<p>Applications Pibrentasvir (CAS# 1353900-92-1) is an antiviral used for hepatitis C virus NS3/4A protease inhibition.<br>References Ng, T. I.; et al.: Antimicrob. Agents Chemother., 62, 1 (2018).<br></p>Fórmula:C57H65F5N10O8Forma y color:Off-White To Light YellowPeso molecular:1113.18Firocoxib-d4
CAS:Producto controlado<p>Applications Labelled Firocoxib (F356002). A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.<br>References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),<br></p>Fórmula:C172H4H16O5SForma y color:NeatPeso molecular:340.43Leflunomide
CAS:Producto controlado<p>Applications An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzucco, G., et al.: Clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med. Chem., 52, 2683 (2009),<br></p>Fórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.211-(4-Hydroxy-3-methoxyphenyl)-1-propanone
CAS:<p>Applications 1-(4-Hydroxy-3-methoxyphenyl)-1-propanone is a derivative of Guaiacol, a precursor to various flavorants, such as eugenol and vanillin.<br>References Allen, C., et al.: Org. Synth., 3, 418 (1955); Esposito, L., et al.: Kirk-Othmer Encyclopedia of Chemical Technology, 4th edition, 24, 812 (1997)<br></p>Fórmula:C10H12O3Forma y color:NeatPeso molecular:180.20N-Boc-L-cis-4,5-Methanoprolineamide
CAS:Producto controlado<p>Applications N-Boc-L-cis-4,5-Methanoprolineamide is an intermediate used to prepare methanoprolinenitrile-contg. dipeptide mimetics as DPP-IV inhibitors and as antidiabetic agents.<br>References Magnin, D., et al.: J. Med. Chem., 47, 2587 (2004)<br></p>Fórmula:C11H18N2O3Forma y color:NeatPeso molecular:226.272[3-cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid
CAS:Pureza:95.0%Peso molecular:375.38000488281253,4-Dihydro Naratriptan Oxalate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Fórmula:C17H23N3O2S·C2H2O4Forma y color:White To Light YellowPeso molecular:333.45 + 90.031,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline
CAS:<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-1)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Fórmula:C10H13NO2Forma y color:White To Light YellowPeso molecular:179.22N-Demethyl Olanzapine
CAS:Producto controlado<p>Applications A metabolite of Olanzapine.<br></p>Fórmula:C16H18N4SForma y color:BrownPeso molecular:298.4117α-Dutasteride
CAS:Producto controlado<p>Impurity Dutateride EP Impurity E<br>Applications 17α-Dutasteride (Dutateride EP Impurity E) is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000).<br></p>Fórmula:C27H30F6N2O2Forma y color:Dark Orange Colour SolidPeso molecular:528.532-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:370.4049987792969Ref: 10-F238631
1gA consultar1mgA consultar5mgA consultar10mgA consultar100mgA consultar250mgA consultar1-[3-(Dimethylamino)propyl]-3-ethylurea
CAS:Producto controlado<p>Applications 1-[3-(Dimethylamino)propyl]-3-ethylurea is a reagent used in the preparation of water soluble, multifunctional antibody-porphyrin gold nanoparticles.<br>References Penon, O. et al.: J. Colloid. Inter. Sci., 496, 100 (2017);<br></p>Fórmula:C8H19N3OForma y color:NeatPeso molecular:173.26Thioridazine Hydrochloride
CAS:Producto controlado<p>Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Fórmula:C21H26N2S2·ClHForma y color:Light YellowPeso molecular:407.04Cathine Hydrochloride
CAS:Producto controladoFórmula:C9H13NO·ClHForma y color:Off-WhitePeso molecular:187.67Axitinib
CAS:Producto controladoFórmula:C22H18N4OSForma y color:Off-White To BeigePeso molecular:386.475-Hydroxypyrazine-2-carboxylic Acid
CAS:<p>Applications A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide (P840600).<br>References Wieser, M. et al.: Appl. Microbiol. Biotech., 48, 174 (1997); Lacroix, C. et al.: Eur. J. Clin. Pharmacol., 36, 395 (1989);<br></p>Fórmula:C5H4N2O3Forma y color:Light YellowPeso molecular:140.10Desbutyl Dronedarone Hydrochloride
CAS:<p>Impurity Dronedarone USP Related Compound A<br>Applications A metabolite of Dronedarone (D679445). Dronedarone impurity D. Dronedarone USP Related Compound A.<br>References Bolderman, R.W. et al.: J Chrom. B:Anal. Tech. Biomed. Life Sci., 887, 1727 (2009); Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009);<br></p>Fórmula:C27H36N2O5S·ClHForma y color:NeatPeso molecular:537.112,6-Dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
CAS:Producto controlado<p>Applications An antitumor nucleoside pyrimido pyrimidine.<br>References Shih, C., et al.: Cancer Res., 57, 1116 (1997), Smith, P., et al.: Clin. Cancer Res., 7, 2105 (2001), Cunningham, D., et al.: Eur. J. Cancer, 38, 478 (2002), Hughes, A., et al.: J. Clin. Oncol., 20, 3533 (2002),<br></p>Fórmula:C16H20Cl2N6Forma y color:NeatPeso molecular:367.28(R)-Praziquantel
CAS:Producto controladoFórmula:C19H24N2O2Forma y color:White To Light YellowPeso molecular:312.41ent-Paroxetine Hydrochloride
CAS:Producto controlado<p>Impurity Paroxetine EP Impurity D; Paroxetine USP Related Compound C<br>Applications ent-Paroxetine Hydrochloride (Paroxetine EP Impurity D; Paroxetine USP Related Compound C) is an enantiomeric impurity of Paroxetine (P205750).<br>References Engelstoft, M. et al.: Acta Chem. Scand. , 50, 164 (1996);<br></p>Fórmula:C19H20FNO3·ClHForma y color:Off-WhitePeso molecular:365.832-Amino-5-methylpyridine
CAS:Producto controlado<p>Applications 2-Amino-5-methylpyridine (cas# 1603-41-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Francotte, P., et al.: Bioorg. Med. Chem., 16, 9948 (2008), Sundaraganesan, N., et al.: J. Mol. Struc., 891, 284 (2008), Caleta, I., et al.: J. Med. Chem., 52, 1744 (2009),<br></p>Fórmula:C6H8N2Forma y color:NeatPeso molecular:108.14Methylfelbamate
CAS:Producto controlado<p>Applications Methylfelbamate is a methyl impurity of felbamate (F231000), which is antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Fórmula:C12H16N2O4Forma y color:NeatPeso molecular:252.27Omeprazole-d3 (benzimidazole-4,6,7-d3)
CAS:Producto controlado<p>Applications Omeprazole-d3 (benzimidazole-4,6,7-d3) (CAS# 934293-92-2) is a useful isotopically labeled research compound.<br></p>Fórmula:C17H16D3N3O3SForma y color:Light BrownPeso molecular:348.4410,11-Dihydro-10-hydroxy Carbamazepine-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Oxcarbazepine (O869250).<br>References Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002), Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002), Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2003), Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690 (2004),<br></p>Fórmula:C152H3H11N2O2Forma y color:Off WhitePeso molecular:257.30Vortioxetine Sulfone
CAS:<p>Applications Vortioxetine Sulfone is a derivative of Vortioxetine (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References Paunovic, A. et al.: ACS Chem. Biol., 12, 132 (2017);<br></p>Fórmula:C18H22N2O2SForma y color:NeatPeso molecular:330.44N-Methyl-N,N-bis(2-pyridylethyl)amine
CAS:<p>Impurity Betahistine EP Impurity C (Free Base)<br>Applications N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes.<br>References Mautner, F.A. et al.: Inorg. Chim. Acta, 362, 4073 (2009);<br></p>Fórmula:C15H19N3Forma y color:NeatPeso molecular:241.33Amido Methyl Meloxicam (Meloxicam Impurity)
CAS:Producto controlado<p>Applications Amido Methyl Meloxicam is an impurity of Meloxicam (M216100).<br>References Lazer, E., et al.: J. Med. Chem., 40, 980 (1997),<br></p>Fórmula:C15H15N3O4S2Forma y color:NeatPeso molecular:365.435-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
CAS:Producto controlado<p>Applications Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),<br></p>Fórmula:C4H2ClF3N2OForma y color:NeatPeso molecular:186.52(±)-Bifonazole
CAS:<p>Applications (±)-Bifonazole acts as an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C22H18N2Forma y color:NeatPeso molecular:310.39Vioxx-d5 (Major)
CAS:Producto controlado<p>Applications A selective labelled cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.<br>References Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999), Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999), Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999),<br></p>Fórmula:C172H5H9O4SForma y color:NeatPeso molecular:319.387(S)-Penbutolol Sulfate
CAS:<p>Stability Hygroscopic<br>Applications (S)-Penbutolol Sulfate is an isomer of Penbutolol (P220500), a β-adrenoceptor antagonist. Antihypertensive.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Fórmula:C18H29NO2·H2O4SForma y color:NeatPeso molecular:680.94Benidipine 5-(1-Benzylpiperidin-3-yl)
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications Benidipine 5-(1-Benzylpiperidin-3-yl) is an impurity of Benidipine (B157500), a dihydropyridine calcium channel blocker. Antihypertensive.<br>References Suzuki, T., et al.: Cardiovasc. Drug Rev., 7, 25 (1989); Hirayama, N., et al.: Acta Crystallogr., C47, 458 (1991)<br></p>Fórmula:C39H44N4O6Forma y color:NeatPeso molecular:664.79Citalopram
CAS:<p>Citalopram (Lu 10-171), a serotonin and 5-HT reuptake inhibitor.Citalopram has antidepressant activity and may be used to study dementia.</p>Fórmula:C20H21FN2OPureza:99.78% - 99.89%Forma y color:SolidPeso molecular:324.39rac-Ruxolitinib-d9 (major)
CAS:Producto controlado<p>Applications Labelled racemic analogue of Ruxolitinib (R702000). Ruxolitinib is a selective Janus tyrosine kinase (JAK1 and JAK2) inhibitor used in the treatment of myeloproliferative neoplasms and psoriasis.<br>References Shilling, A.D. et al.: Drug Metab. Disp., 38, 2023 (2010); Mesa, R.A.: IDrugs, 13, 394 (2010); Campas-Moya, C.: Drugs Fut., 35, 457 (2010);<br></p>Fórmula:C17H9D9N6Forma y color:White To Light YellowPeso molecular:315.42(S)-Naproxen Ethyl Ester
CAS:<p>Impurity Naproxen EP Impurity F<br>Applications Naproxen (N377520) ethyl derivative. Naproxen impurity.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Fórmula:C16H18O3Forma y color:NeatPeso molecular:258.31
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