Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65541 productos de "Derivados de Quinazolina y Quinolina"
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Atrazine
CAS:<p>Applications Selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin; dermatitis, skin sensitization; dyspnea, weakness, incoordination, salivation; hypothermia; liver injury.This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dalgaard-Mikkelsen, S., et al.: Pharmacol. Rev., 14, 225 (1962), Muller, K., et al.: J. Environ. Qual., 31, 309 (2002), Backhaus, T., et al.: Environ. Toxicol. Chem., 23, 258 (2004),<br></p>Fórmula:C8H14ClN5Forma y color:ColourlessPeso molecular:215.68Desamino Chloroimiquimod
CAS:Producto controlado<p>Impurity Imiquimod USP Related Compound C<br>Applications Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Fórmula:C14H14ClN3Forma y color:NeatPeso molecular:259.733-Mercapto-2-methylpropanoic Acid
CAS:Producto controlado<p>Impurity Captopril EP Impurity C<br>Applications 3-Mercapto-2-methylpropanoic Acid (Captopril EP Impurity C) is a useful synthetic intermediate.<br>References Lewis, S.N. et al.: J. Het. Chem., 8, 571-580 (1971)<br></p>Fórmula:C4H8O2SForma y color:NeatPeso molecular:120.176-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxide
CAS:Producto controlado<p>Applications Intermediate in the production of Lornoxicam. An analgesic, anti-inflammatory agent.<br></p>Fórmula:C9H8ClNO5S2Forma y color:NeatPeso molecular:309.75O-Desmethyl Carvedilol
CAS:Producto controlado<p>Applications A metabolite of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Fórmula:C23H24N2O4Forma y color:NeatPeso molecular:392.45Reserpic Acid Methyl Ester
CAS:Producto controlado<p>Applications Reserpine (R144600) derivative, an alkaloid found in Rauwolfia.<br>References Itoh, A. et al.: J. Nat. Prod. 68, 848 (2005)<br></p>Fórmula:C23H30N2O5Forma y color:NeatPeso molecular:414.49GLPG-0634 (Filgotinib)
CAS:Producto controlado<p>Applications GLPG-0634 (Filgotinib) is a potent, selective JAK1 inhibitor. Used as an anti-inflammatory agent, it reduces levels of inflammatory cytokines in the bones and tissue of mammals.<br>References Moran, N. et al.: BioWorld Int., 16, 1 (2011);<br></p>Fórmula:C21H23N5O3SForma y color:NeatPeso molecular:425.55-(4-Nitrophenyl)-2-furaldehyde Azine
CAS:Producto controladoFórmula:C22H14N4O6Forma y color:NeatPeso molecular:430.373,6-Bis(5-bromothiophen-2-yl)-2,5-dioctylpyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Pureza:95%Peso molecular:682.57000732421884,6-Dimethyl-2-hydroxypyrimidine
CAS:Producto controlado<p>Applications 4,6-Dimethyl-2-hydroxypyrimidine is a component of Nicarbazine (N394530), a coccidiostat, which is an antiprotozoal agent that acts upon Coccidia parasites.<br>References Ksenija Sinigoj, G., et al.: Slovenski Kemijski Dnevi, (2012); Kyung-Woo, L., et al.: Han'guk Kagum Hakhoechi, 39, 17 (2012);<br></p>Fórmula:C6H8N2OForma y color:NeatPeso molecular:124.142-(4-Chlorophenoxy)aniline
CAS:Producto controlado<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Fórmula:C12H10ClNOForma y color:NeatPeso molecular:219.674-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride
CAS:Producto controladoFórmula:C14H17N3O4·ClHForma y color:NeatPeso molecular:327.76Demethyl Chlorpromazine Hydrochloride
CAS:Producto controlado<p>Impurity Chlorpromazine EP Impurity D<br>Applications A metabolite of Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Neuhoff, E., et al.: Archiv. der Pharmazie, 288, 400 (1955), Tomita, M., et al.: Chem. Pharm. Bull., 16, 688 (1968),<br></p>Fórmula:C16H17ClN2S·ClHForma y color:WhitePeso molecular:341.30rac 7-Hydroxy Efavirenz
CAS:Producto controladoFórmula:C14H9ClF3NO3Forma y color:NeatPeso molecular:331.674-Hydroxy Nisoldipine
CAS:Producto controlado<p>Applications A metabolite of Nisoldipine<br></p>Fórmula:C20H24N2O7Forma y color:NeatPeso molecular:404.411,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Producto controlado<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Fórmula:C14H13NOForma y color:WhitePeso molecular:211.263-(9H-Carbazol-4-yloxy)-1,2-propanediol
CAS:Producto controlado<p>Applications 3-(9H-Carbazol-4-yloxy)-1,2-propanediol is used in the synthesis of carvedilol, a β-adrenergic blocking agent.<br>References Naidu, K. et al.: Org. Chem. An Indian J., 6, 171 (2010);<br></p>Fórmula:C15H15NO3Forma y color:NeatPeso molecular:257.28Methyl 2-(4-aminophenyl)quinoline-4-carboxylate
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:278.3110046386719Amisulpride
CAS:Producto controlado<p>Applications Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Fórmula:C17H27N3O4SForma y color:WhitePeso molecular:369.482-(6-(4-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperazin-1-yl)-4-oxoquinazolin-3(4H)-yl)acetic acid
CAS:Pureza:97%Peso molecular:510.549987792968757-Hydroxy Chlorpromazine-d6 Hydrochloride
CAS:Producto controlado<p>Applications Labelled analogue of 7-Hydroxychlorpromazine, the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);<br></p>Fórmula:C17H14D6Cl2N2OSForma y color:NeatPeso molecular:377.36Empagliflozin Methyl Acetate
CAS:<p>Applications Empagliflozin Methyl Acetate is an impurity of Empagliflozin (E521510), which is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Fórmula:C25H29ClO8Forma y color:White To Off-WhitePeso molecular:492.95Desethylcarbamoyl Cabergoline
CAS:Producto controlado<p>Impurity Cabergoline EP Impurity D<br>Applications A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum<br>References Battaglia, R., et al.: Xenobiotica, 23, 1377 (1993), Miyagi, M., et al.: Biol. Pharm. Bull., 19, 1210 (1996),<br></p>Fórmula:C23H32N4OForma y color:Beige SolidPeso molecular:380.53(R)-Bicalutamide
CAS:Producto controlado<p>Applications (R)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Fórmula:C18H14F4N2O4SForma y color:WhitePeso molecular:430.37γ-Aminobutyric Acid
CAS:<p>Applications An important inhibitory neurotransmitter. The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.<br>References Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951), Gerlach, M., et al.: Brain Res., 741, 142 (1996), Choi, D., et al.: J Neurobiol 1992, 23, 1261<br></p>Fórmula:C4H9NO2Forma y color:NeatPeso molecular:103.12Ilaprazole
CAS:Producto controlado<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Fórmula:C19H18N4O2SForma y color:NeatPeso molecular:366.44Piperonylic Acid
CAS:Producto controlado<p>Applications Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.<br>References Schalk, M. et al.: Plant Physiol., 118, 209 (1998);<br></p>Fórmula:C8H6O4Forma y color:NeatPeso molecular:166.13rac Penbutolol
CAS:<p>Applications A β-adrenoceptor antagonist. Antihypertensive.<br>References Armstrong, D., et al.: Anal. Chem., 66, 1473 (1994), Kato, M., et al.: J. Pharm. Biomed. Anal., 30, 1845 (2003),<br></p>Fórmula:C18H29NO2Forma y color:Off-WhitePeso molecular:291.433-Acetyl-2(1H)-pyridinone
CAS:Fórmula:C7H7NO2Pureza:98%Forma y color:Solid, CrystallinePeso molecular:137.1382-Chloro-N-(3-chloro-2-methylphenyl)nicotinamide
CAS:<p>Applications An impurity of Clonixine (L488530). Clonixine is a nonsteroidal anti-inflammatory agent used as an analgesic.<br>References Esteve, M.H., et al.: J. High Res. Chromatogr., 13, 445 (1990),<br></p>Fórmula:C13H10Cl2N2OForma y color:Off-WhitePeso molecular:281.14(S)-1-(2-Amino-5-chlorophenyl)-1-(trifluoromethyl)-3-cyclopropyl-2-propyn-1-ol
CAS:Producto controlado<p>Applications Intermediate in the preparation of Efavirenz (E425000) impurity.<br></p>Fórmula:C13H11ClF3NOForma y color:NeatPeso molecular:289.68Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C31H38ClN7O7S2•xH2OForma y color:White To Off-WhitePeso molecular:720.26(R)-3-Aminopiperidine Dihydrochloride
CAS:Producto controlado<p>Applications (R)-3-Aminopiperidine Dihydrochloride has been used as a reactant for the preparation of dipeptidyl peptidase IV inhibitors derived from Alogliptin.<br>References Xie, Hui., et. al.: Eur. J. Med. Chem., 68, 312 (2013)<br></p>Fórmula:C5H14Cl2N2Forma y color:NeatPeso molecular:173.08Deferiprone-d3
CAS:Producto controlado<p>Applications A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro.<br>References Kontoghiorghes, G.J.: Lancet I, 817 (1985), Kontoghiorghes, G.J., et al.: Br. J. Haematol., 62, 607 (1986), Kontoghiorghes, G.J., et al.: Biochem. Biophys. Acta, 869, 141 (1986), Kontoghiorghes, G.J., et al.: Arzneim.-Forsch., 37, 1099 (1987),<br></p>Fórmula:C7H6D3NO2Forma y color:White To Off-WhitePeso molecular:142.17Saquinavir
CAS:Producto controlado<p>Applications Saquinavir (CAS# 127779-20-8) is a useful research chemical compound.<br></p>Fórmula:C38H50N6O5Forma y color:White To Off-WhitePeso molecular:670.842,6-Dimethylaniline-d6
CAS:Producto controlado<p>Applications Labelled Bupivacaine (B689560) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lepage, F., et al.: Eur. J. Med. Chem., 27, 581 (1992), Thummel, K.E., et al.: Drug Metab. Dispos., 21, 350 (1993)<br></p>Fórmula:C82H6H5NForma y color:BrownPeso molecular:127.22rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid
CAS:Producto controlado<p>Applications rac N-Propyl-2-cyanimidopyrrolidine-5-acetic Acid is a potent peptidic renin inhibitor. Pramipexole Related Compound<br></p>Fórmula:C10H15N3O2Forma y color:NeatPeso molecular:209.24
![6-Chloro-4-hydroxy-2-methyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxylic Acid Methyl Ester 1,1-Dioxi…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC366630.webp&w=3840&q=75)
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![4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA616975.webp&w=3840&q=75)
