Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65541 productos de "Derivados de Quinazolina y Quinolina"
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Benzophenone-2,3,4,5,6-d5
CAS:Producto controlado<p>Applications Benzophenone-2,3,4,5,6-d5 is derived from Benzene-d6 (B185282), which is an isotope labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>Fórmula:C13D5H5OForma y color:NeatPeso molecular:187.251-Difluoromethyl-3,5-dimethyl-1H-pyrazole-4-sulfonyl chloride
CAS:Fórmula:C6H7ClF2N2O2SForma y color:LiquidPeso molecular:244.641-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide
CAS:Producto controlado<p>Impurity Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite<br>Applications 1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide (Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite) is a metabolite of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Alexandre, V., et. al.: J. Mol. Catal. B-Enzym., 29, 173 (2004); Rao, D.D., et. al.: J. Liq. Chromatogr. R. T., 35, 1973 (2012)<br></p>Fórmula:C25H30N6O2Forma y color:NeatPeso molecular:446.54Dehydro Nifedipine
CAS:Producto controlado<p>Impurity Nifedipine EP Impurity A<br>Applications The main Nifedipine metabolite in human plasma.This compound is a contaminant of emerging concern (CECs).<br>References Guengerich, F., et al.: J. Biol. Chem., 261, 5051 (1986), Bork, R., et al.: J. Biol. Chem., 264, 910 (1989), Kerla, V., et al.: Biochem. Pharmacol., 44, 1745 (1992),<br></p>Fórmula:C17H16N2O6Forma y color:Light YellowPeso molecular:344.32Metaraminol Bitartrate
CAS:Producto controlado<p>Applications Metaraminol Bitartrate is a vasopressor comparable to ephedrine used in the maintenance of arterial pressure during spinal anesthesia. Also used in the treatment of hypotension while under the effect of anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ngan, K. et al.: Anesthes., 95, 307 (2001); Critchley, L. et al.: Br. J. Anaesth., 76, 734 (1996);<br></p>Fórmula:C9H13NO2·C4H6O6Forma y color:WhitePeso molecular:317.29Salsalate-d8
CAS:Producto controlado<p>Applications Isotope labelled Nonacetylated aspirin analog. Analgesic, anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, L.L., et al.: J. Pharm. Sci., 69, 1268 (1980), Dromgoole, S.M., et al.: J. Pharm. Sci., 73, 1657 (1984),<br></p>Fórmula:C14H2D8O5Forma y color:NeatPeso molecular:266.28Riluzole 4-Trifluoromethoxy Isomer
CAS:Producto controlado<p>Applications Riluzole 4-Trifluoromethoxy Isomer is an impurity of Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.<br>References Satyanarayana, B., et. al.: ARKIVOC, 14, 109 (2008); Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSForma y color:NeatPeso molecular:234.20MDV 3100 (Enzalutamide)
CAS:Producto controlado<p>Applications MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br>References Scher, H.I. et al.: Lancet, 375, 1437 (2010); Bellmunt, J. et al.: Ther. Adv. Med. Oncol., 2, 189 (2010); Ryan, C.J. et al.: J. Clin. Oncol., 29, 3651 (2011);<br></p>Fórmula:C21H16F4N4O2SForma y color:WhitePeso molecular:464.444-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole
CAS:Producto controlado<p>Applications 4-Methyl-1-[3-nitro-5-(trifluoromethyl)phenyl]-1H-imidazole, is a 4-methyl-1H-imidazole (4-MEI) derivative.<br></p>Fórmula:C11H8F3N3O2Forma y color:Light YellowPeso molecular:271.20Bicalutamide Sulfide
CAS:Producto controladoFórmula:C18H14F4N2O2SForma y color:WhitePeso molecular:398.37(+/-)-4-Hydroxy Mephenytoin
CAS:Producto controlado<p>Applications CYP2C19 metabolite of Mephenytoin.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980)<br></p>Fórmula:C12H14N2O3Forma y color:White SolidPeso molecular:234.253-(2-Chloroethyl)-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Producto controlado<p>Impurity Paliperidone USP Related Compound C<br>Applications Paliperidone USP Related Compound C<br></p>Fórmula:C11H15ClN2O2Forma y color:Light Yellow To BrownPeso molecular:242.70Bisdionin C
CAS:Producto controlado<p>Applications Bisdionin C is the derivative of Theobromine (T343800), which is a metabolite of Caffeine.<br>References Suto, M., et al.: Anticancer Drug Des., 6, 107 (1991), Burkart, V., et al.: Nat. Med., 5, 314 (1999), Hassa, P., et al.: J. Biol. Chem., 278, 45145 2003), Veres, B., et al.: J. Pharmacol. Exp. Ther., 310, 247(2004)<br></p>Fórmula:C17H20N8O4Forma y color:NeatPeso molecular:400.39Roflumilast-d4 N-Oxide
CAS:Producto controlado<p>Applications Labelled Roflumilast-N-oxide (R639710). Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Fórmula:C17H10D4Cl2F2N2O4Forma y color:NeatPeso molecular:423.23Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate Hydrochloride
<p>Applications Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate is an impurity of Hexamidine Diisetionate (H294205), which is an amidine compound used in the treatment of amyloid-related diseases; it is also used as preservative in cosmetics as an antispetic.<br>References Siddall, T., et al.: J. Org. Chem., 31, 3719 (1966)<br></p>Fórmula:C22H28N2O4·HClForma y color:NeatPeso molecular:384.47 +(36.46)Oxethazaine
CAS:<p>Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain.</p>Fórmula:C28H41N3O3Pureza:99.875% - 99.94%Forma y color:Physical Description White Powder (Ntp 1992)Peso molecular:467.64Desthiazolylmethyl Ritonavir
CAS:Producto controlado<p>Impurity Ritonavir EP Impurity L<br>Applications Desthiazolylmethyl Ritonavir (Ritonavir EP Impurity L) is an analogue of the selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.<br>References Brittain, H., et al.: Pharm. Res., 8, 963 (1991), Sham, H., et al.: J. Med. Chem., 39, 392 (1996), Phadnis, N., et al.: J. Pharm. Sci.,86, 1256 (1997), Bauer, J., et al.: Pharma. Res., 18, 859 (2001),<br></p>Fórmula:C33H43N5O4SForma y color:White To Off-WhitePeso molecular:605.798-methyl-2-(4-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:90.0%Peso molecular:277.322998046875Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS:Pureza:95.0%Peso molecular:367.3999938964844Ethyl 2-(2-(2-fluorophenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS:Pureza:98%Peso molecular:456.489990234375N-Desmethyl Tadalafil
CAS:Producto controlado<p>Applications A N-desmethyl analogue of the human PDE5 inhibitor Tadalafil (T004500). A potential antiplasmodial drug.<br>References Beghyn, T. et al.: Bioorg. Med. Chem. Lett., 17, 789 (2007); Daugan, A. et al.: J. Med. Chem., 46, 4533 (2003);<br></p>Fórmula:C21H17N3O4Forma y color:White SolidPeso molecular:375.38(2-methoxyethyl)(2-thienylmethyl)amine hydrochloride
CAS:Fórmula:C8H14ClNOSForma y color:SolidPeso molecular:207.72Demethyl Benzydamine Hydrochloride
CAS:Producto controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OForma y color:Off White SolidPeso molecular:331.84Risperidone EP Impurity J
CAS:<p>Impurity Risperidone EP Impurity J<br>Applications 3-[2-[4-[(Z)-(4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl)phenyl](hydroxyimino)methyl]piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity J) is a Risperidone (R525000) impurity.<br></p>Fórmula:C35H40F2N6O3Forma y color:White To YellowPeso molecular:630.7273Ref: 10-F521408
1gA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar250mgA consultar2,3-Dichloro-5,6-dicyanobenzoquinone
CAS:<p>Applications An oxidizing agent, especially in steroid synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C8Cl2N2O2Forma y color:NeatPeso molecular:227.0(S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
CAS:Pureza:95.0%Peso molecular:351.92999267578125Ref: 10-F214928
1gA consultar2gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultar6-Iodo-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Pureza:98%Peso molecular:329.0929870605469Tert-Butyl 4-chloro-2-morpholino-5H-pyrrolo[2,3-d]pyrimidine-7(6H)-carboxylate
CAS:Pureza:95.0%Peso molecular:340.809997558593752-[5-fluoro-2-(pyridin-2-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:291.75Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
CAS:Producto controlado<p>Applications Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors.<br>References Gant, T., et.al., PCT Int.Appl., 113,(2008);<br></p>Fórmula:C15D4H10N4OForma y color:NeatPeso molecular:270.3310H-Phenothiazine
CAS:Pureza:95.0%Forma y color:Solid, Crystalline Powder or Flakes or Pellets or PowderPeso molecular:199.27000427246094(1S,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Producto controlado<p>Applications An intermediate in the synthesis of thephosphodiesterase 5 inhibitor Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Fórmula:C20H18N2O4Forma y color:White To YellowPeso molecular:350.371-(4-pyridinyl)-N-(4-pyridinylmethyl)methanamine hydrochloride
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:235.72000122070312[5-Chloro-3-(4-chloro-phenyl)-1-phenyl-1H-pyrazol-4-yl]-methanol
CAS:Pureza:95.0%Peso molecular:319.19000244140625Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Fórmula:C13H16N2Pureza:99.88%Forma y color:SolidPeso molecular:200.28Ethyl 2-phenyl-3-(trifluoromethyl)pyrazole-4-carboxylate
CAS:Fórmula:C13H11F3N2O2Pureza:95.0%Forma y color:LiquidPeso molecular:284.238
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