Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65630 productos de "Derivados de Quinazolina y Quinolina"
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Nateglinide Ethyl Ester
CAS:Producto controlado<p>Applications The ethyl ester of the oral hypoglycemic agent Nateglinide (N379375). It showed no effects on gross behavior in mice.<br>References Maeda, K. et al.: Yak. Chir., 25, S157 (1997);<br></p>Fórmula:C21H31NO3Forma y color:NeatPeso molecular:345.48N-(2-Succinyl) Phenylephrine(Mixture of Diastereomers) ( >85%)
CAS:<p>Impurity N-(2-Succinyl) Phenylephrine Impurity<br>Applications The major degradation product identified in Acetaminophen, Phenylephrine hydrochloride, and Chlorpheniramine maleate.<br>References Wong, J., et al.: Anal. Chem., 78, 7891 (2006),<br></p>Fórmula:C13H17NO6Pureza:>85%Forma y color:NeatPeso molecular:283.28Pyrazinenitrile
CAS:Producto controlado<p>Impurity Pyrazinamide EP Impurity B<br>Applications Pyrazinenitrile (Pyrazinamide EP Impurity) is used as a single-source precursor in the synthesis of metal-free nitrogen-doped carbon nanoparticles (NCNPs). Also, it is an important intermediate in the production of pyrazinamide as an effective anti-tubercular drug.<br>References Panomsuwan, G., et al.: Carbon, 98, 411-420 (2016); Radnik, J., et al.: Catal. Commun., 71, 97-101 (2015);<br></p>Fórmula:C5H3N3Forma y color:ColourlessPeso molecular:105.17-Methoxy-1-naphthaleneethanamine Hydrochloride
CAS:Producto controladoFórmula:C13H15NO·ClHForma y color:NeatPeso molecular:237.731-(3-Nitropyridin-2-yl)piperidine-4-carbonitrile
CAS:Fórmula:C11H12N4O2Pureza:95.0%Peso molecular:232.2435-Aminothiophene-2-carbonitrile
CAS:Fórmula:C5H4N2SPureza:98%Forma y color:SolidPeso molecular:124.164-Hydroxy Omeprazole Preparation Kit
CAS:Producto controladoFórmula:C16H17N3O3SForma y color:Off White SolidPeso molecular:331.395-Amino-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-1H-pyrazole-4-carbonitrile
Pureza:95.0%Peso molecular:242.238006591796888-methyl-4-(pyridine-3-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:305.33401489257816-(Butylamino)-N-(2,6-dimethylphenyl)hexanamide
CAS:Producto controlado<p>Applications 6-(Butylamino)-N-(2,6-dimethylphenyl)hexanamide is a structural isomer of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Fórmula:C18H30N2OForma y color:White To Off-WhitePeso molecular:290.44Loxapine N-Oxide
CAS:<p>Stability Hygroscopic, Light Sensitive<br>Applications Loxapine N-Oxide is a metabolite of Loxapine (L472750), a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Fórmula:C18H18ClN3O2Forma y color:NeatPeso molecular:343.812-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-5,6-dimethylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:287.33999633789064-Phenyl-2-(pyridin-3-yl)thiazole
CAS:Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:238.30999755859375Zaltoprofen
CAS:Producto controlado<p>Applications Zaltoprofen is a non-steroidal anti-inflammatory drug. It inhibits bradykinin-induced pain responses without blocking bradykinin receptors.<br>References Hirate, K., et al.: Nerosci. Res., 54, 288 (2006); Yamamoto, M., et al.: Chirality, 2, 280 (1990); Inoue, M., et al.: J Pharmacol. Exp. Ther., 293, 662 (2000); Graven-Nielsen, T., et al.: Clin. J. Pain, 17, 2 (2001)<br></p>Fórmula:C17H14O3SForma y color:NeatPeso molecular:298.36Thiophene-2-carboximidic acid ethyl ester; hydrochloride
CAS:Pureza:95.0%Peso molecular:191.6699981689453Nizatidine
CAS:Producto controlado<p>Applications Histamine H2-receptor antagonist related to Ranitidine (R120000). Antiulcerative.<br>References Callaghan, J.T., et al.: Clin. Pharmacol. Ther., 37, 162 (1985), Secor, J.W., et al.: Br. J. Clin. Pharmacol., 20, 710 (1985), Knadler, M.P., et al.: Drug Metab. Dispos., 14, 175 (1986), Wozniak, T.J., et al.: Anal. Profiles Drug Subs., 19, 397(1990)<br></p>Fórmula:C12H21N5O2S2Forma y color:Off-White To Light YellowPeso molecular:331.464-(3-fluorophenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:271.30999755859375rac-Methyl Ephedrine-d3 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Ephedrine derivative for controlling respiratory tract goblet cell hyperplasia in respiratory diseases including infection and bronchitis.<br>References Tan, Z., et al.: J. Therm. Anal., 45, 59 (1995), van Berkel, G., et al.: Anal. Chem., 76, 479 (2004), Di, Y., et al.: Chin. Phy., 17, 3276 (2008),<br></p>Fórmula:C112H3H14NO·ClHForma y color:NeatPeso molecular:218.742-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS:Producto controlado<p>Applications An anticoccidal triazine used for the treatment of coccidiosis in chickens. An impurity of Diclazuril (D436200).<br>References McFarland, J. et al.: J. Med. Chem., 35, 2543 (1992);<br></p>Fórmula:C16H10Cl3N3O2Forma y color:NeatPeso molecular:382.63Desmethyl Nintedanib
CAS:Producto controlado<p>Applications Desmethyl Nintedanib is an impurity of Intedanib (I666650), which is an antitumor agent. Desmethyl Nintedanib was used in the study of synthesizing indolinones as triple angiokinase inhibitors.<br>References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009);<br></p>Fórmula:C30H31N5O4Forma y color:NeatPeso molecular:525.6Domperidone-d6
CAS:Producto controlado<p>Applications A novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic.<br>References Baudry, M., et al.: Arch. Pharmacol., 308, 231 (1979), Ennis, C., et al.: J. Pharm. Pharmacol., 31, 14 (1979), Brogden, R.N., Drugs, 24, 360 (1982),<br></p>Fórmula:C22H18D6ClN5O2Forma y color:NeatPeso molecular:431.95Ethyl 6-ethynylpicolinate
CAS:Fórmula:C10H9NO2Pureza:98%Forma y color:Liquid, No data available.Peso molecular:175.187Propoxyphenyl Thioaildenafil
CAS:Producto controlado<p>Applications Propoxyphenyl Thioaildenafil is an analogue of Thioaildenafil (T344365). Propoxyphenyl Thioaildenafil is a phosphodiesterase-5 inhibitor (PDE-5) that has been found in health supplements.<br>References Kee, C., Ge, X., Koh, H., Low, M.: J. Pharmaceut. Biomed., 70, 265 (2012)<br></p>Fórmula:C24H34N6O3S2Forma y color:NeatPeso molecular:518.71-(1-Propyl-1H-pyrazol-4-yl)ethylamine
CAS:Fórmula:C8H15N3Pureza:97%Forma y color:SolidPeso molecular:153.229[4-(5-pyridin-3-yl-1H-1,2,4-triazol-3-yl)phenyl]amine
CAS:Pureza:95.0%Peso molecular:237.266006469726568-methyl-2-(5-methyl-2-thienyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:283.3500061035156diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylidene}malonate
CAS:Peso molecular:281.312011718751-Benzhydrylpiperazine
CAS:Producto controladoFórmula:C17H20N2Forma y color:White To BeigePeso molecular:252.35Cabozantinib Des-O-fluoroaniline
CAS:Producto controlado<p>Applications Cabozantinib Des-O-fluoroaniline is a degradation product of Cabozantinib(C051500). Cabozantinib is a small molecule C-Met modulator. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.<br>References Camp, R., et al.: Cancer, 86, 2259 (1999), Morello, S., et al.: J. Cell Physiol., 189, 285 (2001), Zhang, Y., et al.: Oncogene, 21, 217 (2002), Wells, S., et al.: J. Clin. Oncol., 28, 767 (2010); Wu, C., et al.: J. Pharm. Biomed. Anal., 98, 356 (2014)<br></p>Fórmula:C22H20N2O6Forma y color:NeatPeso molecular:408.42-Chloropyridine
CAS:Producto controlado<p>Applications 2-Chloropyridine (2-CPY) has been identified as a trace organic chemical in process streams, wastewater and even drinking water. Furthermore, it appears to be formed as a secondary pollutant during the decomposition of specific insecticides. 2-CPY was found to be genotoxic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Demsia, G., et al.: Mutat. Res., 634, 32 (2007), Stapleton, D., et al.: Water Res., 43, 3964 (2009),<br></p>Fórmula:C5H4ClNForma y color:NeatPeso molecular:113.54Meclizine
CAS:Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptorsFórmula:C25H27ClN2Pureza:99.55%Forma y color:SolidPeso molecular:390.952,2-Diphenylhydantoic Acid
CAS:<p>Impurity Phenytoin USP Related Compound B<br>Applications 2,2-Diphenylhydantoic Acid is metabolite of Phenytoin, an anticonvulsant. Phenytoin USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Van Espen, J., et al.: J. De. Pharma. De. Belgique., 7, 451 (1952); Stella, V., et al.: J. Org. Chem., 38, 1527 (1973);<br></p>Fórmula:C15H14N2O3Forma y color:NeatPeso molecular:270.283-(3,5-Dimethyl-pyrazol-1-ylmethyl)-phenylamine
CAS:Fórmula:C12H15N3Pureza:98%Forma y color:Low Melting SolidPeso molecular:201.273Hydroxy-2-phenylpropyl Carbamate
CAS:Producto controlado<p>Applications Hydroxy-2-phenylpropyl Carbamate is an impurity in the synthesis of Felbamate (F231000), an antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Fórmula:C10H13NO3Forma y color:NeatPeso molecular:195.22Valsartan Methyl Ester
CAS:Producto controlado<p>Impurity Valsartan USP Related Compound E<br>Applications Valsartan Methyl Ester (Valsartan USP Related Compound E) is an analog of Valsartan (V095750), is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C25H31N5O3Forma y color:NeatPeso molecular:449.55
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