Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65630 productos de "Derivados de Quinazolina y Quinolina"
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rac-Talinolol
CAS:Producto controlado<p>Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Fórmula:C20H33N3O3Forma y color:White To Light PinkPeso molecular:363.49Ref: 10-F625925
1gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarDomperidone N-Oxide
CAS:Producto controlado<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Fórmula:C22H24ClN5O3Forma y color:White To Off-WhitePeso molecular:441.91(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)methanol
CAS:Fórmula:C12H18BNO3Pureza:96.0%Forma y color:SolidPeso molecular:235.09Nizatidine Sulfoxide
CAS:Producto controladoFórmula:C12H21N5O3S2Forma y color:NeatPeso molecular:347.46N-[1-(1H-1,2,3-Benzotriazol-1-yl)-3-phenylpropyl]pyridine-4-carboxamide
Peso molecular:357.4169921875A77 1726-d4
CAS:Producto controlado<p>Applications The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function.<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Fórmula:C122H4H5F3N2O2Forma y color:Off-WhitePeso molecular:274.23N-Formyl Lenalidomide
CAS:Producto controladoFórmula:C14H13N3O4Forma y color:NeatPeso molecular:287.273-Desamino-3,4-dehydro Sitagliptin
CAS:<p>Impurity Sitagliptin Tablets EP Impurity FP-C<br>Applications 3-Desamino-3,4-dehydro Sitagliptin is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.<br>References Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005); Bergman, A., et al: Clin. Ther. 28, 55 (2006)<br></p>Fórmula:C16H12F6N4OForma y color:White To Off-WhitePeso molecular:390.28Blonanserin-d5
CAS:Producto controlado<p>Applications Labelled Blonanserin (B595850). A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.<br>References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),<br></p>Fórmula:C23H25D5FN3Forma y color:NeatPeso molecular:372.53Amido Methyl Meloxicam (Meloxicam Impurity)
CAS:Producto controlado<p>Applications Amido Methyl Meloxicam is an impurity of Meloxicam (M216100).<br>References Lazer, E., et al.: J. Med. Chem., 40, 980 (1997),<br></p>Fórmula:C15H15N3O4S2Forma y color:NeatPeso molecular:365.434-Diphenylmethoxypiperidine hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Fórmula:C18H21NO·ClHForma y color:WhitePeso molecular:303.833-Hydroxy-2-pyrone
CAS:Producto controlado<p>Applications 3-Hydroxy-2-pyrone<br></p>Fórmula:C5H4O3Forma y color:NeatPeso molecular:112.08Norfloxacin Nicotinate
CAS:Producto controlado<p>Applications Norfloxacin nicotinate is a fluoroquinolone antibacterial agent that is a norfloxacin derivative with improved solubility in water.<br></p>Fórmula:C16H18FN3O3·C6H5NO2Forma y color:NeatPeso molecular:319.33 + (123.11)(±)-Bifonazole
CAS:<p>Applications (±)-Bifonazole acts as an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C22H18N2Forma y color:NeatPeso molecular:310.39Cilnidipine
CAS:Producto controlado<p>Applications A dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992), Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992), Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993),<br></p>Fórmula:C27H28N2O7Forma y color:NeatPeso molecular:492.524-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}benzaldehyde
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:267.2070007324219Prochlorperazine Edisylate
CAS:Producto controladoFórmula:C20H24ClN3S·C2H6O6S2Forma y color:NeatPeso molecular:564.145-azetidin-3-yl-3-(3-thienyl)-1,2,4-oxadiazole hydrochloride
CAS:Pureza:95.0%Peso molecular:243.7100067138672N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)-3-(trifluoromethyl)pyridine-2-sulfonamide
CAS:Pureza:98%Forma y color:SolidPeso molecular:407.3200073N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Producto controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Forma y color:NeatPeso molecular:425.43(3S,3'S)-4,4'-(7-Chloropyrido[2,3-d]pyrimidine-2,4-diyl)bis(3-methylmorpholine)
CAS:Pureza:95.0%Peso molecular:363.85000610351561-Benzyl-3-(2,4-dimethylphenyl)-1H-pyrazole-5-carboxylic acid
Pureza:95.0%Peso molecular:306.364990234375(R)-1-Boc-3-hydroxypiperidine
CAS:Producto controlado<p>Applications (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. (R)-1-Boc-3-hydroxypiperidine has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et. al.: J. Labelled Comptd. Rad., 44, 31 (2001); Isakovic, L., et. al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009)<br></p>Fórmula:C10H19NO3Forma y color:NeatPeso molecular:201.26Methyl 4-(((4-(pyridin-3-yl)pyrimidin-2-yl)amino)methyl)benzoate
CAS:Pureza:95+%Peso molecular:320.35198974609375Desethylene Aripiprazole
CAS:<p>Impurity Aripiprazole Desethylene Impurity<br>Applications Desethylene Aripiprazole is an Aripiprazole derivative. Aripiprazole Desethylene Impurity<br></p>Fórmula:C21H25Cl2N3O2Forma y color:NeatPeso molecular:422.35(E)-N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE
CAS:Pureza:95.0%Peso molecular:391.5150146484375(S)-Naproxen Ethyl Ester
CAS:<p>Impurity Naproxen EP Impurity F<br>Applications Naproxen (N377520) ethyl derivative. Naproxen impurity.<br>References Haddock, R., et al.: Xenobiotica, 14, 327 (1984), Jeremy, J., et al.: Drugs, 40, 53 (1990), Wadhwa, L., et al.: Int. J. Pharm., 118, 31 (1995),<br></p>Fórmula:C16H18O3Forma y color:NeatPeso molecular:258.31Thiazolylmethyl-4-nitrophenylcarbonate
CAS:Producto controlado<p>Applications Retinovir intermediate.<br>References Randad, R., et al.: Bioorg. Med. Chem. Lett., 4, 1247 (1994), Scholz, et al.: J. Med. Chem., 37, 3079 (1994), Vacca, J., et al.: Bioorg. Med. Chem. Lett., 4, 499 (1994),<br></p>Fórmula:C11H8N2O5SForma y color:Light YellowPeso molecular:280.262-((3-(4-Cyanonaphthalen-1-yl)pyridin-4-yl)thio)-N-(methylsulfonyl)acetamide 2,2,2-trifluoroacetate
Pureza:97%Peso molecular:511.491-(4-Chlorophenyl)-3-(1-methyl-1H-pyrazol-4-yl)propane-1,3-dione
CAS:Pureza:97.0%Peso molecular:262.69000244140625Gabapentin-d4 (100 μg/mL in Methanol)
CAS:Producto controladoFórmula:C9D4H13NO2Forma y color:Single SolutionPeso molecular:175.26(S)-O-Desmethyl Naproxen
CAS:Producto controlado<p>Applications A metabolite of Naproxen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),<br></p>Fórmula:C13H12O3Forma y color:WhitePeso molecular:216.23Oxaprozin-d10
CAS:Producto controlado<p>Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).<br>References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)<br></p>Fórmula:C18H5D10NO3Forma y color:NeatPeso molecular:303.38Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:Producto controlado<p>Applications Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Nevuluri, N. et al.: Monat. fuer Chem., 148, 1477 (2017);<br></p>Fórmula:C22H22N4O4Forma y color:NeatPeso molecular:406.434-[6-(2-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.315002441406254-Chloromethyl-5-methyl-1,3-dioxol-2-one
CAS:Producto controlado<p>Applications 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.<br>References Ikeda, S. et al.: Chem. Pharmac. Bull., 32, 4316 (1984); Wu, T. Yaox. Xueb., 41, 537 (2006);<br></p>Fórmula:C5H5ClO3Forma y color:NeatPeso molecular:148.543-Methoxy-4-nitro-1H-pyrazole-5-carboxylic acid
CAS:Fórmula:C5H5N3O5Pureza:95.0%Forma y color:SolidPeso molecular:187.111Prochlorperazine Sulfoxide-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Prochlorperazine.<br>References Finn, A., et al.: J. Clin. Pharmacol., 45, 1383 (2005),<br></p>Fórmula:C202H3H21ClN3OSForma y color:Off WhitePeso molecular:392.96Des(methoxycarbonyl) Febantel
CAS:Producto controlado<p>Applications Febantel (F227000) impurity. Anthelmintic.<br>References Wollweber, H., et al.: Arzneim.-Forsch., 34, 531 (1984),<br></p>Fórmula:C18H20N4O4SForma y color:NeatPeso molecular:388.445- tert -Butyl-2-methyl-4-nitro-2 H -pyrazole-3-carboxylic acid
CAS:Fórmula:C9H13N3O4Pureza:97%Forma y color:SolidPeso molecular:227.22
![N-[1-(1H-1,2,3-Benzotriazol-1-yl)-3-phenylpropyl]pyridine-4-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF183221.webp&w=3840&q=75)
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![(3S,3'S)-4,4'-(7-Chloropyrido[2,3-d]pyrimidine-2,4-diyl)bis(3-methylmorpholine)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF229684.webp&w=3840&q=75)
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