Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4964 productos de "Esteroides y derivados"
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a-Epoxyabiraterone Acetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H33NO3Forma y color:NeatPeso molecular:407.55Des[[N-(1,1-Dimethylethyl)amino]carbonyl] 17-(Propionyl) Finasteride
CAS:Producto controlado<p>Applications An impurity of Finasteride (F342000).<br></p>Fórmula:C21H31NO2Forma y color:NeatPeso molecular:329.48D-Homoanalog of Triamcinolone
CAS:Producto controlado<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Fórmula:C21H27FO6Forma y color:NeatPeso molecular:394.43Desisobutyryl Ciclesonide
CAS:Producto controlado<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Fórmula:C28H38O6Forma y color:White To Off-WhitePeso molecular:470.60N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Producto controlado<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Fórmula:C25H38N2O2Forma y color:NeatPeso molecular:398.582-Hydroxy Atorvastatin Lactone
CAS:Producto controlado<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Fórmula:C33H33FN2O5Forma y color:Off White SolidPeso molecular:556.62Testosterone-16,16,17-d3 Benzoate
CAS:Producto controladoFórmula:C26H29D3O3Forma y color:NeatPeso molecular:395.5617β-Dihydro Equilin-16,16,17-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C182H3H17O2Forma y color:NeatPeso molecular:271.37Obeticholic Acid Methyl Ester
CAS:Producto controlado<p>Applications Obeticholic Acid Methyl Ester is a bile acid derivative useful in research.<br>References Pellicciari, R., et al.: Journal of Medicinal Chemistry, 50, 4265 (2007)<br></p>Fórmula:C27H46O4Forma y color:NeatPeso molecular:434.6525-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS:<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Fórmula:C40H65N3O4SForma y color:NeatPeso molecular:684.03Testosterone Cypionate-d3 (1 mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C27D3H37O3Forma y color:Single SolutionPeso molecular:415.62(2Z)-2,3-Dehydroxy Atorvastatin (>90% Z)
CAS:<p>Applications (2Z)-2,3-Dehydroxy Atorvastatin is an intermediate in synthesizing (2E)-2,3-Dehydroxy Atorvastatin (D230045), which is an impurity in the synthesis of Atorvastatin (A791750).<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);<br></p>Fórmula:C33H33FN2O4Forma y color:NeatPeso molecular:540.621,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS:<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C28H39FO7Forma y color:NeatPeso molecular:506.60δ6-Gestodene
Producto controlado<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.416-Keto Dexamethasone
Producto controlado<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Fórmula:C22H27FO6Forma y color:NeatPeso molecular:406.44δ6-Fulvestrant
CAS:Producto controlado<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Fórmula:C32H45F5O3SForma y color:NeatPeso molecular:604.756-Dehydro Nandrolone Acetate
CAS:Producto controladoFórmula:C20H26O3Forma y color:NeatPeso molecular:314.42Testosterone 17-O-Acetate-d3 (1mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C21H27D3O3Forma y color:ColourlessPeso molecular:333.48
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